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The map label for this gene is pkn1 [H]

Identifier: 159898158

GI number: 159898158

Start: 1891530

End: 1892321

Strand: Reverse

Name: pkn1 [H]

Synonym: Haur_1634

Alternate gene names: 159898158

Gene position: 1892321-1891530 (Counterclockwise)

Preceding gene: 159898160

Following gene: 159898157

Centisome position: 29.82

GC content: 53.79

Gene sequence:

>792_bases
ATGAAGGAAGCCCAATTGAAGCAAATTCGTGATCTCTTGCCCAAGTTTTGCCCAATTCCACGGGGCATCGTGCTAATGGG
CACGCCTAACGAGCAATTAAGTGATTTGGCTAAACGTTTTGGTGGCACGCGTGAGTCATATGCGGAAGAAGCGCCCCAGC
ATCCAGTCGAAATTGCCGCCTTTGCCATGGCCCAAGTTCCGGTAACCAACGCCCTATATGCCGAATGGATCAAGCATTCA
GGCCAGCGTGCGCCAATTGTCTGGCATGGTTCGCAACCACCTGCCGAATTAGCCGACTATCCAGTGGTTGATGTAACTTG
GGATGAAGCGGTAGCATGTTGCGATTGGCTCAGCAGCGAAGTTAATTTGGCTTTGCGCTTGCCTAGCGAGGCCGAGTGGG
AACGCGCTGCACGTGGCGATGATACGCGGATCTATCCTTGGGGCGATCAGGCTGACTCAACAATGATGAATATCAAAGAA
AGCATGCGCGGCGGCTTAGCTCCGGTTGGCAGTTATCCCCAAGCAGCCAGCCCATTCGGGGTTTACGATCTGGCGGGCAA
TATTTGGGAATGGACAAGTTCGCTGCAAAAATCGTATCCCTATAATGCTGATGATGGCCGCGAAGCTCGCCAACCAGCGC
CAGAGGCTGATCGACGGCGGATTATGCGCGGCGGTTGTTGGGGTAACCCCGGCCATTTTGCCCGCAATACCTGTCGTTTC
CGCCTGCATCCCGAGCGTTCAACCCATTTATTGGGCTTTCGGCTGGCCTATAGCTTGCTAGAGAGTGATTAA

Upstream 100 bases:

>100_bases
CCACCAGCCATTGCCAACGAATCTGTTGCAACATACAAACTCCTTTCGATCAGTATGCAAAATCTGGTATCTTTAGAGCC
ACAAACAAGCATTTTTTGGC

Downstream 100 bases:

>100_bases
ATACTGGCTCAATTCAATCGAAAAAAAAGCCAAAAGCGTGGTATAATCGCAGGCTATTCACGGGTAGCTAATCTAGCATC
CAGCTAGCATATCGAGCAGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MKEAQLKQIRDLLPKFCPIPRGIVLMGTPNEQLSDLAKRFGGTRESYAEEAPQHPVEIAAFAMAQVPVTNALYAEWIKHS
GQRAPIVWHGSQPPAELADYPVVDVTWDEAVACCDWLSSEVNLALRLPSEAEWERAARGDDTRIYPWGDQADSTMMNIKE
SMRGGLAPVGSYPQAASPFGVYDLAGNIWEWTSSLQKSYPYNADDGREARQPAPEADRRRIMRGGCWGNPGHFARNTCRF
RLHPERSTHLLGFRLAYSLLESD

Sequences:

>Translated_263_residues
MKEAQLKQIRDLLPKFCPIPRGIVLMGTPNEQLSDLAKRFGGTRESYAEEAPQHPVEIAAFAMAQVPVTNALYAEWIKHS
GQRAPIVWHGSQPPAELADYPVVDVTWDEAVACCDWLSSEVNLALRLPSEAEWERAARGDDTRIYPWGDQADSTMMNIKE
SMRGGLAPVGSYPQAASPFGVYDLAGNIWEWTSSLQKSYPYNADDGREARQPAPEADRRRIMRGGCWGNPGHFARNTCRF
RLHPERSTHLLGFRLAYSLLESD
>Mature_263_residues
MKEAQLKQIRDLLPKFCPIPRGIVLMGTPNEQLSDLAKRFGGTRESYAEEAPQHPVEIAAFAMAQVPVTNALYAEWIKHS
GQRAPIVWHGSQPPAELADYPVVDVTWDEAVACCDWLSSEVNLALRLPSEAEWERAARGDDTRIYPWGDQADSTMMNIKE
SMRGGLAPVGSYPQAASPFGVYDLAGNIWEWTSSLQKSYPYNADDGREARQPAPEADRRRIMRGGCWGNPGHFARNTCRF
RLHPERSTHLLGFRLAYSLLESD

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=280, Percent_Identity=29.2857142857143, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI194248087, Length=254, Percent_Identity=30.7086614173228, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI194248088, Length=177, Percent_Identity=35.5932203389831, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI226437577, Length=177, Percent_Identity=35.5932203389831, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI38202250, Length=305, Percent_Identity=27.8688524590164, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI257470977, Length=234, Percent_Identity=29.0598290598291, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI20130397, Length=297, Percent_Identity=24.9158249158249, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 29472; Mature: 29472

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEAQLKQIRDLLPKFCPIPRGIVLMGTPNEQLSDLAKRFGGTRESYAEEAPQHPVEIAA
CCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHCCCCCHHHHH
FAMAQVPVTNALYAEWIKHSGQRAPIVWHGSQPPAELADYPVVDVTWDEAVACCDWLSSE
HHHHHCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHCCCEEEECHHHHHHHHHHHCCC
VNLALRLPSEAEWERAARGDDTRIYPWGDQADSTMMNIKESMRGGLAPVGSYPQAASPFG
CEEEEECCCHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
VYDLAGNIWEWTSSLQKSYPYNADDGREARQPAPEADRRRIMRGGCWGNPGHFARNTCRF
HHHHHCHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHHHCCCCCCCCHHHCCCEEE
RLHPERSTHLLGFRLAYSLLESD
EECCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEAQLKQIRDLLPKFCPIPRGIVLMGTPNEQLSDLAKRFGGTRESYAEEAPQHPVEIAA
CCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHCCCCCHHHHH
FAMAQVPVTNALYAEWIKHSGQRAPIVWHGSQPPAELADYPVVDVTWDEAVACCDWLSSE
HHHHHCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHCCCEEEECHHHHHHHHHHHCCC
VNLALRLPSEAEWERAARGDDTRIYPWGDQADSTMMNIKESMRGGLAPVGSYPQAASPFG
CEEEEECCCHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
VYDLAGNIWEWTSSLQKSYPYNADDGREARQPAPEADRRRIMRGGCWGNPGHFARNTCRF
HHHHHCHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHHHCCCCCCCCHHHCCCEEE
RLHPERSTHLLGFRLAYSLLESD
EECCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]