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The map label for this gene is cvrA [H]

Identifier: 159897991

GI number: 159897991

Start: 1708826

End: 1710289

Strand: Reverse

Name: cvrA [H]

Synonym: Haur_1466

Alternate gene names: 159897991

Gene position: 1710289-1708826 (Counterclockwise)

Preceding gene: 159897992

Following gene: 159897986

Centisome position: 26.95

GC content: 50.2

Gene sequence:

>1464_bases
ATGAGCACAGAAAGCATTTTTGTCATCGCCGGAAGTTTGGTGCTAATTAGCATTATTGTCAGCACCTTATCGGATCGCTG
GGGGATTCCGGCCTTGGTGCTGTTTATGGGCATTGGCATGCTCGCTGGCTCTGACGGCCCTGGCGATATCAATTTCGATA
ATGCGGCAGTTGCCCAAGTAGTCGGGATTGTCGCGCTGATTTATATTTTGTTCTCGGGTGGCCTTGAAACCCATTGGCAT
CGAATTCGAGCAGTCATTGGCCCAGGCTTATTGCTAGCCAACATTGGAGTGGTGATTAGCGCCAGTATGGTAGCAGCAAT
TGCAGTTTGGCTGTTTGATTTGCCACCAGTTGTTGGCTTATTGTTGGGGGCAATTATTTCCTCAACTGATGCCGCAGCCG
TGTTCAATGTGCTTCGCACGCGGGGAGTACGCCTGCCTGAGCCAGTTGAATCGCTGATCGAGCTAGAATCGGGCAGCAAT
GATCCAATCGCCGTGTTTTTAACGATTGGGCTGACGAGTTATCTAACCAGTAGCGGCCATTCGGTGGGCGCGTTGGCCAT
CGAGTTTGTGCTCGAAATGGTTTTAGGGGTGGTGATTGGTGGGCTTGGTGGCTACCTAATCACATGGCTGATCAATCGGT
TACGTCTGCAAGATGGGCTTTATCCAGTCTTGACCTTATCGATGACGATTATGGTGTATGGGGCGGCCATGTTGGTGCAT
GGCAATGGCTTCTTGGCGGTGTATGTGGCAGGTTTGGTGGTTGGCAATCGGCCAATTATTCACCGCCGCAGTTTAATTCG
CTTTCACGAGGGGATTGCCTGGCTGATGCAAATTGCCATGTTCTTAACTTTGGGATTGTTGGTTTACCCATCACAACTTG
TCCCATTAATTGGCAAAGGCCTGTTGCTGGCAATCTTTTTGATGTTTATTGCACGACCAATCAGCGTGATTGTGGCACTC
GGCTGGACGCGCTTCAAGTTGCGCGAACGCTTGATGATTAGCTGGGCAGGCCTACGCGGAGCTGTGCCAATTGTGTTGGC
AACATTTCCATTGATAGCGGGAGTTCCCCAAGCCAACGATATGTTTCATTTAATTTTCTTCGTCGTGCTGGCCTCAGTTA
CGGTGCAGGGAATGAGCATTGGTTGGGTGGCTGATCGGCTAAAACTCAATTCACATGATATTCAAATCAACAGCATGCCC
TTGGATTTTATTCCTGAGATCAGCCCTGAGAGTACCGTTTACGAGGTGGTTGTGCCTGATGATGCCCGTTTAGCTGGGCG
CAACATTATGGAATTGCAACTGCCACGCGGCGCGTTAGTTGTGCTAATTCGGCGTGGGCGTGAGACGATTGTGCCCAGCG
GCAACACGCGGGTTCAAGCCAACGACAAAATTCTGATGTTGGCCGATCAACAGGCGCTTGAGGTAATTAACCAACGCCTA
AATATTGCCAACCAAGCTGCATAA

Upstream 100 bases:

>100_bases
GGCAGGCTTGTATCCAGCGTGGAAAATGGGGCGTACCTCGCCAGCGTTGGCGTTGCGGGAAGAATAGCATTCGGGCACAG
GCGTGCTCAAAAGGAGGCCA

Downstream 100 bases:

>100_bases
TGCCAAACACTGACCCCTTGCTCAACCATGTGGGCAAGGGGTCAAATCGGCTATTGTTCGATGACGGTAATCGCTTCGGC
AGGCGTTTTCTCGCCATACA

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MSTESIFVIAGSLVLISIIVSTLSDRWGIPALVLFMGIGMLAGSDGPGDINFDNAAVAQVVGIVALIYILFSGGLETHWH
RIRAVIGPGLLLANIGVVISASMVAAIAVWLFDLPPVVGLLLGAIISSTDAAAVFNVLRTRGVRLPEPVESLIELESGSN
DPIAVFLTIGLTSYLTSSGHSVGALAIEFVLEMVLGVVIGGLGGYLITWLINRLRLQDGLYPVLTLSMTIMVYGAAMLVH
GNGFLAVYVAGLVVGNRPIIHRRSLIRFHEGIAWLMQIAMFLTLGLLVYPSQLVPLIGKGLLLAIFLMFIARPISVIVAL
GWTRFKLRERLMISWAGLRGAVPIVLATFPLIAGVPQANDMFHLIFFVVLASVTVQGMSIGWVADRLKLNSHDIQINSMP
LDFIPEISPESTVYEVVVPDDARLAGRNIMELQLPRGALVVLIRRGRETIVPSGNTRVQANDKILMLADQQALEVINQRL
NIANQAA

Sequences:

>Translated_487_residues
MSTESIFVIAGSLVLISIIVSTLSDRWGIPALVLFMGIGMLAGSDGPGDINFDNAAVAQVVGIVALIYILFSGGLETHWH
RIRAVIGPGLLLANIGVVISASMVAAIAVWLFDLPPVVGLLLGAIISSTDAAAVFNVLRTRGVRLPEPVESLIELESGSN
DPIAVFLTIGLTSYLTSSGHSVGALAIEFVLEMVLGVVIGGLGGYLITWLINRLRLQDGLYPVLTLSMTIMVYGAAMLVH
GNGFLAVYVAGLVVGNRPIIHRRSLIRFHEGIAWLMQIAMFLTLGLLVYPSQLVPLIGKGLLLAIFLMFIARPISVIVAL
GWTRFKLRERLMISWAGLRGAVPIVLATFPLIAGVPQANDMFHLIFFVVLASVTVQGMSIGWVADRLKLNSHDIQINSMP
LDFIPEISPESTVYEVVVPDDARLAGRNIMELQLPRGALVVLIRRGRETIVPSGNTRVQANDKILMLADQQALEVINQRL
NIANQAA
>Mature_486_residues
STESIFVIAGSLVLISIIVSTLSDRWGIPALVLFMGIGMLAGSDGPGDINFDNAAVAQVVGIVALIYILFSGGLETHWHR
IRAVIGPGLLLANIGVVISASMVAAIAVWLFDLPPVVGLLLGAIISSTDAAAVFNVLRTRGVRLPEPVESLIELESGSND
PIAVFLTIGLTSYLTSSGHSVGALAIEFVLEMVLGVVIGGLGGYLITWLINRLRLQDGLYPVLTLSMTIMVYGAAMLVHG
NGFLAVYVAGLVVGNRPIIHRRSLIRFHEGIAWLMQIAMFLTLGLLVYPSQLVPLIGKGLLLAIFLMFIARPISVIVALG
WTRFKLRERLMISWAGLRGAVPIVLATFPLIAGVPQANDMFHLIFFVVLASVTVQGMSIGWVADRLKLNSHDIQINSMPL
DFIPEISPESTVYEVVVPDDARLAGRNIMELQLPRGALVVLIRRGRETIVPSGNTRVQANDKILMLADQQALEVINQRLN
IANQAA

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG3263

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=478, Percent_Identity=42.6778242677824, Blast_Score=316, Evalue=2e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018421
- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 52392; Mature: 52261

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTESIFVIAGSLVLISIIVSTLSDRWGIPALVLFMGIGMLAGSDGPGDINFDNAAVAQV
CCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
VGIVALIYILFSGGLETHWHRIRAVIGPGLLLANIGVVISASMVAAIAVWLFDLPPVVGL
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGAIISSTDAAAVFNVLRTRGVRLPEPVESLIELESGSNDPIAVFLTIGLTSYLTSSGH
HHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHCCCC
SVGALAIEFVLEMVLGVVIGGLGGYLITWLINRLRLQDGLYPVLTLSMTIMVYGAAMLVH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEE
GNGFLAVYVAGLVVGNRPIIHRRSLIRFHEGIAWLMQIAMFLTLGLLVYPSQLVPLIGKG
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCH
LLLAIFLMFIARPISVIVALGWTRFKLRERLMISWAGLRGAVPIVLATFPLIAGVPQAND
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCH
MFHLIFFVVLASVTVQGMSIGWVADRLKLNSHDIQINSMPLDFIPEISPESTVYEVVVPD
HHHHHHHHHHHHHHHCCCEEEHHHHHHEECCCEEEEECCCHHHCCCCCCCCEEEEEEECC
DARLAGRNIMELQLPRGALVVLIRRGRETIVPSGNTRVQANDKILMLADQQALEVINQRL
CCCCCCCCEEEEECCCCEEEEEEECCCCEECCCCCCEEEECCCEEEEECHHHHHHHHHHH
NIANQAA
HHHHCCC
>Mature Secondary Structure 
STESIFVIAGSLVLISIIVSTLSDRWGIPALVLFMGIGMLAGSDGPGDINFDNAAVAQV
CCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
VGIVALIYILFSGGLETHWHRIRAVIGPGLLLANIGVVISASMVAAIAVWLFDLPPVVGL
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGAIISSTDAAAVFNVLRTRGVRLPEPVESLIELESGSNDPIAVFLTIGLTSYLTSSGH
HHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHCCCC
SVGALAIEFVLEMVLGVVIGGLGGYLITWLINRLRLQDGLYPVLTLSMTIMVYGAAMLVH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEE
GNGFLAVYVAGLVVGNRPIIHRRSLIRFHEGIAWLMQIAMFLTLGLLVYPSQLVPLIGKG
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCH
LLLAIFLMFIARPISVIVALGWTRFKLRERLMISWAGLRGAVPIVLATFPLIAGVPQAND
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCH
MFHLIFFVVLASVTVQGMSIGWVADRLKLNSHDIQINSMPLDFIPEISPESTVYEVVVPD
HHHHHHHHHHHHHHHCCCEEEHHHHHHEECCCEEEEECCCHHHCCCCCCCCEEEEEEECC
DARLAGRNIMELQLPRGALVVLIRRGRETIVPSGNTRVQANDKILMLADQQALEVINQRL
CCCCCCCCEEEEECCCCEEEEEEECCCCEECCCCCCEEEECCCEEEEECHHHHHHHHHHH
NIANQAA
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA