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The map label for this gene is map [H]

Identifier: 159897663

GI number: 159897663

Start: 1296379

End: 1297131

Strand: Direct

Name: map [H]

Synonym: Haur_1134

Alternate gene names: 159897663

Gene position: 1296379-1297131 (Clockwise)

Preceding gene: 159897662

Following gene: 159897664

Centisome position: 20.43

GC content: 50.6

Gene sequence:

>753_bases
ATGGCAATCAGAATCTACAATCAATCGCAAATTAATGAAATGCGCAAAGCTGGCCAATTGGTTGCCAAAGCCCATGCGAT
GTTGCGCGAATATGTGGTGGCTGGAGCAGTCTTACTGGAGCTTGATCAGCGGGTCGAGCAATTTTTGCGTGATCATGGCG
CAACCCCATCATTCAAAGGCCATGGCGGTTTTCCAGCCTCAACCTGTATCTCGGTCAACGATGTAGTATGTCATGGCATT
CCTGATAAATCGCGGCTGAGCAATGGTGATATTGTTTCAATCGATATTGGAGCATGTTTAGATGGCTGGCATGGCGATTC
GTGTGTAACCTACGCGGTAGGCAAGCTCGATTCGCAAAGCGCCAAGTTGATGAAGGTAACTGAGGAAGCGATGTGGCGTG
GGATCGCCCAAGCCCGCGCCGGCAAAACCATCGGCGATATTGGCGCAGCAATGCAAGAATACACCGAAAGCCAAGGGTTT
TCGGTGGTGCGCGAATACACGGGCCATGGTATTGGCCGCAAAATGCATGAAACGCCACCTGATGTTTTTAATTTTGGCGA
ATGGGGCAAAGGGCTAAAACTGCGAGCAGGCATGACGCTCACAATCGAACCAATTGTCAACATCGGCTCGGCCCGCACTC
GCTTGCTACGCGATGGCTGGACTGCCAAAACCGCCGATGGCTCTCGTTCGGCTCAATTTGAACATCAACTAGCGATCACC
ACTGGTGATCCGGAAATTTTAACCAAATTATGA

Upstream 100 bases:

>100_bases
CTGGACGGTTAAAACGGTCGATGGCTCACGCTCAGCTCAATTTGAACATCAACTAGCGGTCACCGATGGTGAACCAGATA
TTTTAACGGTGCTTTAAACA

Downstream 100 bases:

>100_bases
AATTAACCAAACGCTATCTAAGCCTTGGAATAATGGTTTTGGCGATTTTGGCGCTTGATCGCTGGGTCAAATGGTGGGCG
CTCGACACGCTTACGCCCTT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MAIRIYNQSQINEMRKAGQLVAKAHAMLREYVVAGAVLLELDQRVEQFLRDHGATPSFKGHGGFPASTCISVNDVVCHGI
PDKSRLSNGDIVSIDIGACLDGWHGDSCVTYAVGKLDSQSAKLMKVTEEAMWRGIAQARAGKTIGDIGAAMQEYTESQGF
SVVREYTGHGIGRKMHETPPDVFNFGEWGKGLKLRAGMTLTIEPIVNIGSARTRLLRDGWTAKTADGSRSAQFEHQLAIT
TGDPEILTKL

Sequences:

>Translated_250_residues
MAIRIYNQSQINEMRKAGQLVAKAHAMLREYVVAGAVLLELDQRVEQFLRDHGATPSFKGHGGFPASTCISVNDVVCHGI
PDKSRLSNGDIVSIDIGACLDGWHGDSCVTYAVGKLDSQSAKLMKVTEEAMWRGIAQARAGKTIGDIGAAMQEYTESQGF
SVVREYTGHGIGRKMHETPPDVFNFGEWGKGLKLRAGMTLTIEPIVNIGSARTRLLRDGWTAKTADGSRSAQFEHQLAIT
TGDPEILTKL
>Mature_249_residues
AIRIYNQSQINEMRKAGQLVAKAHAMLREYVVAGAVLLELDQRVEQFLRDHGATPSFKGHGGFPASTCISVNDVVCHGIP
DKSRLSNGDIVSIDIGACLDGWHGDSCVTYAVGKLDSQSAKLMKVTEEAMWRGIAQARAGKTIGDIGAAMQEYTESQGFS
VVREYTGHGIGRKMHETPPDVFNFGEWGKGLKLRAGMTLTIEPIVNIGSARTRLLRDGWTAKTADGSRSAQFEHQLAITT
GDPEILTKL

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=249, Percent_Identity=38.1526104417671, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI164420681, Length=247, Percent_Identity=36.4372469635627, Blast_Score=164, Evalue=6e-41,
Organism=Escherichia coli, GI1786364, Length=250, Percent_Identity=43.2, Blast_Score=216, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI71996291, Length=217, Percent_Identity=41.9354838709677, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6323273, Length=250, Percent_Identity=36.8, Blast_Score=161, Evalue=9e-41,
Organism=Drosophila melanogaster, GI24583427, Length=245, Percent_Identity=36.734693877551, Blast_Score=178, Evalue=3e-45,
Organism=Drosophila melanogaster, GI21355531, Length=247, Percent_Identity=38.8663967611336, Blast_Score=171, Evalue=3e-43,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 27144; Mature: 27013

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIRIYNQSQINEMRKAGQLVAKAHAMLREYVVAGAVLLELDQRVEQFLRDHGATPSFKG
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
HGGFPASTCISVNDVVCHGIPDKSRLSNGDIVSIDIGACLDGWHGDSCVTYAVGKLDSQS
CCCCCHHHEEEECCEEEECCCCHHHCCCCCEEEEECCCCCCCCCCCCEEEHEECCCCCCH
AKLMKVTEEAMWRGIAQARAGKTIGDIGAAMQEYTESQGFSVVREYTGHGIGRKMHETPP
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCC
DVFNFGEWGKGLKLRAGMTLTIEPIVNIGSARTRLLRDGWTAKTADGSRSAQFEHQLAIT
CCCCCCCCCCCEEEECCCEEEEHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEE
TGDPEILTKL
CCCHHHHHCC
>Mature Secondary Structure 
AIRIYNQSQINEMRKAGQLVAKAHAMLREYVVAGAVLLELDQRVEQFLRDHGATPSFKG
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
HGGFPASTCISVNDVVCHGIPDKSRLSNGDIVSIDIGACLDGWHGDSCVTYAVGKLDSQS
CCCCCHHHEEEECCEEEECCCCHHHCCCCCEEEEECCCCCCCCCCCCEEEHEECCCCCCH
AKLMKVTEEAMWRGIAQARAGKTIGDIGAAMQEYTESQGFSVVREYTGHGIGRKMHETPP
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCC
DVFNFGEWGKGLKLRAGMTLTIEPIVNIGSARTRLLRDGWTAKTADGSRSAQFEHQLAIT
CCCCCCCCCCCEEEECCCEEEEHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEE
TGDPEILTKL
CCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842; 7559358 [H]