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The map label for this gene is mtnP [H]

Identifier: 159897660

GI number: 159897660

Start: 1294201

End: 1294962

Strand: Direct

Name: mtnP [H]

Synonym: Haur_1131

Alternate gene names: 159897660

Gene position: 1294201-1294962 (Clockwise)

Preceding gene: 159897659

Following gene: 159897661

Centisome position: 20.39

GC content: 53.54

Gene sequence:

>762_bases
ATGATTTTATTGCTCGGTGGCACAGGAACTTATTTTCTTGAGCTTGAGGCCACGCTGGGAGCTGGCAATTACCAAACGAT
TGAAACGCCCTACGGCACAGCTGGCTCGATCTATCAACCAGAGCGTTTTGCTGGCAAAATTGGCCTTGCTTCGCGCCACG
GTTGGGGCCGTTTGGATGTTTCGCCGCCCTTCGTCAATAGTCGCGCTAATATTTGGGCCGCCAAAGAGCTGGGCTACCAA
AACATTCTTAGCTGGAACGGGGTCGGGGCAATCAATCAATTATTGCAAGTACACGATTTGGTCGTGCTCAACCATGTGCT
GAATGGCACCAAAACCCGCCCGATCAATTTTGCTGGCGATCTGCCCAACGCCAGTGCTTGGCAGATTGCTCAGCGGGTGT
TTGATCCAGCCAGCGCCAGCGTGCTTTACCAGCAGGCGCGACGCTATCAAGCCCGCAGCTTCGATTGTGGCACCTATGCC
TGTTCAGAAGGGCCACGCCTCGAAACCGCCGCCGAAATTCGGGCTTGGGCCAATTTTGGAGCCGATGTGGTGGGCATGAC
GCTGGTGCCAGAAGTATTATTGGCCTACGAATTAGGCATTAAATTTGCCTCGTTGGCCTATGTGACCAATTTTGCCACTG
GCGTGGAACCAAGCACTGGCGCACCACGTTTCTTTGGAGTCGAAGTCGCCCAAACTTGTCTGCAAATTGTGCTAGCGACT
GCCGAGCAATTGTTGGCAACTAACGAGGTGAGCACCCAATGA

Upstream 100 bases:

>100_bases
CTGGCCATCTAATTGAGTATGCTGATGCTGAATTTTTGGATGAATCAGCGCCGAGCAATGAGCATGATGATGACGATGAT
TTGATGTATTTGGGGGGCGC

Downstream 100 bases:

>100_bases
GCTTTACCATAACCTCACTCAATACCCCGTTTGGGCTGGCGATGTTTGCCACCAAAAGCAGCGCTGGCGGCTCCTTGGCA
ATTCTGCTTGATGAACCAAA

Product: purine phosphorylase family 2

Products: NA

Alternate protein names: 5'-methylthioadenosine phosphorylase; MTA phosphorylase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MILLLGGTGTYFLELEATLGAGNYQTIETPYGTAGSIYQPERFAGKIGLASRHGWGRLDVSPPFVNSRANIWAAKELGYQ
NILSWNGVGAINQLLQVHDLVVLNHVLNGTKTRPINFAGDLPNASAWQIAQRVFDPASASVLYQQARRYQARSFDCGTYA
CSEGPRLETAAEIRAWANFGADVVGMTLVPEVLLAYELGIKFASLAYVTNFATGVEPSTGAPRFFGVEVAQTCLQIVLAT
AEQLLATNEVSTQ

Sequences:

>Translated_253_residues
MILLLGGTGTYFLELEATLGAGNYQTIETPYGTAGSIYQPERFAGKIGLASRHGWGRLDVSPPFVNSRANIWAAKELGYQ
NILSWNGVGAINQLLQVHDLVVLNHVLNGTKTRPINFAGDLPNASAWQIAQRVFDPASASVLYQQARRYQARSFDCGTYA
CSEGPRLETAAEIRAWANFGADVVGMTLVPEVLLAYELGIKFASLAYVTNFATGVEPSTGAPRFFGVEVAQTCLQIVLAT
AEQLLATNEVSTQ
>Mature_253_residues
MILLLGGTGTYFLELEATLGAGNYQTIETPYGTAGSIYQPERFAGKIGLASRHGWGRLDVSPPFVNSRANIWAAKELGYQ
NILSWNGVGAINQLLQVHDLVVLNHVLNGTKTRPINFAGDLPNASAWQIAQRVFDPASASVLYQQARRYQARSFDCGTYA
CSEGPRLETAAEIRAWANFGADVVGMTLVPEVLLAYELGIKFASLAYVTNFATGVEPSTGAPRFFGVEVAQTCLQIVLAT
AEQLLATNEVSTQ

Specific function: Catalyzes the formation of methylthio-D-ribose 1- phosphate (MTR-1-P) from methylthioadenosine (MTA) [H]

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI47132622, Length=219, Percent_Identity=32.4200913242009, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI71980569, Length=213, Percent_Identity=30.9859154929577, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI20130079, Length=214, Percent_Identity=28.0373831775701, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI221459247, Length=188, Percent_Identity=32.9787234042553, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010044
- InterPro:   IPR000845
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.28 [H]

Molecular weight: Translated: 27306; Mature: 27306

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLLGGTGTYFLELEATLGAGNYQTIETPYGTAGSIYQPERFAGKIGLASRHGWGRLDV
CEEEEECCCEEEEEEEEEECCCCCEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCEECC
SPPFVNSRANIWAAKELGYQNILSWNGVGAINQLLQVHDLVVLNHVLNGTKTRPINFAGD
CCCCCCCCCCEEEHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCC
LPNASAWQIAQRVFDPASASVLYQQARRYQARSFDCGTYACSEGPRLETAAEIRAWANFG
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHCC
ADVVGMTLVPEVLLAYELGIKFASLAYVTNFATGVEPSTGAPRFFGVEVAQTCLQIVLAT
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEECHHHHHHHHHHHHHH
AEQLLATNEVSTQ
HHHHHHCCCCCCC
>Mature Secondary Structure
MILLLGGTGTYFLELEATLGAGNYQTIETPYGTAGSIYQPERFAGKIGLASRHGWGRLDV
CEEEEECCCEEEEEEEEEECCCCCEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCEECC
SPPFVNSRANIWAAKELGYQNILSWNGVGAINQLLQVHDLVVLNHVLNGTKTRPINFAGD
CCCCCCCCCCEEEHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCC
LPNASAWQIAQRVFDPASASVLYQQARRYQARSFDCGTYACSEGPRLETAAEIRAWANFG
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHCC
ADVVGMTLVPEVLLAYELGIKFASLAYVTNFATGVEPSTGAPRFFGVEVAQTCLQIVLAT
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEECHHHHHHHHHHHHHH
AEQLLATNEVSTQ
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]