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The map label for this gene is cobO [H]

Identifier: 159897589

GI number: 159897589

Start: 1212137

End: 1213168

Strand: Reverse

Name: cobO [H]

Synonym: Haur_1060

Alternate gene names: 159897589

Gene position: 1213168-1212137 (Counterclockwise)

Preceding gene: 159897594

Following gene: 159897588

Centisome position: 19.12

GC content: 50.48

Gene sequence:

>1032_bases
ATGAGCGATGCCCCACTGACGATGCGAGCCTATGGCCGCCATTTATTTATTTGTACTGGTGATCAATGTAATGGCGACGC
TGACGGCGCGGCCTTAGCCCAACATGCGCTTGAGCAACTCGGCGATCGGCGCAAATTACGCAATCCCGAACGGGTCAAAT
GCTCTACGGTCAGTTGTTTGGGTGTTTGCCAACGCGGCCCGATTGCGGTGGTTTATCCCGAAGGCATTTGGTATCAGCAG
CTTGATCACGATTTAGTTGAACAAATTGTGCAAGAGCATTTGATCAATGGCGAGCCAGTTGAGGCAGCGATTTTCCATCG
GCTGTATCCAGCGGGCCAAGAGCCAGAATATGCCCCAGCAGTGCGCGGCGATCAAGCATTTAATCCAATTGAATTACAAC
CCGATGATGCGGTTGAGCAATTGGAACCAATCGTCGTTGCTGGCACGCAACTGCATTCAACCGAAGAAAAACAGCGCTAT
CGCGAACAAGTACGCAAATTGCGCAAAGGCAAAAAAGGCCTTGTGATCGTCAATACCGGTAATGGCAAGGGCAAAACGTC
AGCGGCATTGGGTGTCATGACTAGGGCGTGGGGTCGCGATCTCAAGGTTAAAGTCATTCAATTTCTCAAACACGAAAATG
CCAAGTTTGGCGAATCGCGGGCGGCTGCCAAGATGGAAATTGAGTTTGGTGGCACTGGCGATGGCTTCACGTGGACCTCG
AAAGATCTTGATGCGACCAAAGCCAAAGCCTTACATGGCTGGGAATTGGCTAAAACCGCGATTAGCTCGAATCAATATCA
GATTGTCATTCTCGATGAATTTACCTATGTGATGGCTTTTGGTTGGCTCGATGTCAACGAGGTTGTGGCTTGGTTGGCGG
CCAACAAGCCTGAATTATTGCATGTGATTATTACAGGCCGCGATGCACCTGCTGCCCTGATCGAACACGCCGACCTTGTA
ACCGAGATGCGCGAAATTAAACACCCGTTTACGACTCAAGGCATTCGTGCCCAGATCGGGATTGACTTCTGA

Upstream 100 bases:

>100_bases
AGACCCTGCTGGGTTTAGCGCCTCTTTTCCTCTTTGGCATGAGCCGAAGAGGTTTTTTCTTGGCTGTTTGCATGCTGGTG
TGTCGTCCAACGGAGCCAGC

Downstream 100 bases:

>100_bases
TGACTGAACGTTTGCAACGCAATATGGTCGAGCGCATCGATGGACGCATGGTCAACGCTGGTTATAAACGCGGCATGTTG
TTTATCTGCGCTCATGGCTG

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSDAPLTMRAYGRHLFICTGDQCNGDADGAALAQHALEQLGDRRKLRNPERVKCSTVSCLGVCQRGPIAVVYPEGIWYQQ
LDHDLVEQIVQEHLINGEPVEAAIFHRLYPAGQEPEYAPAVRGDQAFNPIELQPDDAVEQLEPIVVAGTQLHSTEEKQRY
REQVRKLRKGKKGLVIVNTGNGKGKTSAALGVMTRAWGRDLKVKVIQFLKHENAKFGESRAAAKMEIEFGGTGDGFTWTS
KDLDATKAKALHGWELAKTAISSNQYQIVILDEFTYVMAFGWLDVNEVVAWLAANKPELLHVIITGRDAPAALIEHADLV
TEMREIKHPFTTQGIRAQIGIDF

Sequences:

>Translated_343_residues
MSDAPLTMRAYGRHLFICTGDQCNGDADGAALAQHALEQLGDRRKLRNPERVKCSTVSCLGVCQRGPIAVVYPEGIWYQQ
LDHDLVEQIVQEHLINGEPVEAAIFHRLYPAGQEPEYAPAVRGDQAFNPIELQPDDAVEQLEPIVVAGTQLHSTEEKQRY
REQVRKLRKGKKGLVIVNTGNGKGKTSAALGVMTRAWGRDLKVKVIQFLKHENAKFGESRAAAKMEIEFGGTGDGFTWTS
KDLDATKAKALHGWELAKTAISSNQYQIVILDEFTYVMAFGWLDVNEVVAWLAANKPELLHVIITGRDAPAALIEHADLV
TEMREIKHPFTTQGIRAQIGIDF
>Mature_342_residues
SDAPLTMRAYGRHLFICTGDQCNGDADGAALAQHALEQLGDRRKLRNPERVKCSTVSCLGVCQRGPIAVVYPEGIWYQQL
DHDLVEQIVQEHLINGEPVEAAIFHRLYPAGQEPEYAPAVRGDQAFNPIELQPDDAVEQLEPIVVAGTQLHSTEEKQRYR
EQVRKLRKGKKGLVIVNTGNGKGKTSAALGVMTRAWGRDLKVKVIQFLKHENAKFGESRAAAKMEIEFGGTGDGFTWTSK
DLDATKAKALHGWELAKTAISSNQYQIVILDEFTYVMAFGWLDVNEVVAWLAANKPELLHVIITGRDAPAALIEHADLVT
EMREIKHPFTTQGIRAQIGIDF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=192, Percent_Identity=39.0625, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 38034; Mature: 37903

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAPLTMRAYGRHLFICTGDQCNGDADGAALAQHALEQLGDRRKLRNPERVKCSTVSCL
CCCCCEEHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHH
GVCQRGPIAVVYPEGIWYQQLDHDLVEQIVQEHLINGEPVEAAIFHRLYPAGQEPEYAPA
HHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
VRGDQAFNPIELQPDDAVEQLEPIVVAGTQLHSTEEKQRYREQVRKLRKGKKGLVIVNTG
CCCCCCCCCCCCCCCHHHHHCCCEEEECCCHHCHHHHHHHHHHHHHHHCCCCCEEEEECC
NGKGKTSAALGVMTRAWGRDLKVKVIQFLKHENAKFGESRAAAKMEIEFGGTGDGFTWTS
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCEECC
KDLDATKAKALHGWELAKTAISSNQYQIVILDEFTYVMAFGWLDVNEVVAWLAANKPELL
CCCCHHHHHHHCCHHHHHHHHCCCCEEEEEEECEEEEHHCCCCCHHHHHHHHHCCCCCEE
HVIITGRDAPAALIEHADLVTEMREIKHPFTTQGIRAQIGIDF
EEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCC
>Mature Secondary Structure 
SDAPLTMRAYGRHLFICTGDQCNGDADGAALAQHALEQLGDRRKLRNPERVKCSTVSCL
CCCCEEHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHH
GVCQRGPIAVVYPEGIWYQQLDHDLVEQIVQEHLINGEPVEAAIFHRLYPAGQEPEYAPA
HHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
VRGDQAFNPIELQPDDAVEQLEPIVVAGTQLHSTEEKQRYREQVRKLRKGKKGLVIVNTG
CCCCCCCCCCCCCCCHHHHHCCCEEEECCCHHCHHHHHHHHHHHHHHHCCCCCEEEEECC
NGKGKTSAALGVMTRAWGRDLKVKVIQFLKHENAKFGESRAAAKMEIEFGGTGDGFTWTS
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCEECC
KDLDATKAKALHGWELAKTAISSNQYQIVILDEFTYVMAFGWLDVNEVVAWLAANKPELL
CCCCHHHHHHHCCHHHHHHHHCCCCEEEEEEECEEEEHHCCCCCHHHHHHHHHCCCCCEE
HVIITGRDAPAALIEHADLVTEMREIKHPFTTQGIRAQIGIDF
EEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]