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The map label for this gene is hldE [H]

Identifier: 159897558

GI number: 159897558

Start: 1174960

End: 1175940

Strand: Reverse

Name: hldE [H]

Synonym: Haur_1029

Alternate gene names: 159897558

Gene position: 1175940-1174960 (Counterclockwise)

Preceding gene: 159897559

Following gene: 159897557

Centisome position: 18.53

GC content: 52.7

Gene sequence:

>981_bases
GTGCATGAATTAACTGCCACGCTAGCCAAATTAAGCCAACAACGGGTCTTAATTGTTGGCGATGTTATGCTCGATGAATA
TATTTGGGGCGATGTGACCCGCATTTCGCCTGAAGCGCCAGTGCCAATCGTCAATGTGCGTTCGCGCAGCTATCGGCCAG
GCGGAGCTAGCAACGTTGCCGCCAGTATTGCCGCACTGAATGCCGAGGTGCTGCTTGGCGGGGTGATCGGCGACGATTTG
GCAGGCCAACAGCTCAAAATTGCCCTCCAACAGGCGGGCGTTGCTGATAGCACAGGCTTGATCAGTGCTCAACGCCCAAC
CACGCTCAAAACCCGCATCATCGCCCATAACCAACAGATGTTGCGCTATGATAGCGAGGTCAGCACGGCGCTTGATGAAG
CGAGCGAAGCAGCACTGTGCGCTTGGGTTGATCAACAGATTGCTAATTGCCAAGTTTGTATTCTCTCGGATTATGCCAAG
GGGGTGCTGACTGAGCGAATTTGCCAGCATGTGATTCAACAGGCACGGTATTACAACATTCCGGTGGTGGTTGATCCCAA
GGGCATCAATTATCAGCGTTATGCCCAAGCCAGCGTAATTACGCCTAATCTGCAAGAAACCCAAGTTGTGACTGGGCTAA
GCCTCCAAACGCTTGAACAACTGCACCATGCTGCTGATCAATTGTTGGATTTGCTGCAAGGTGCAGCGCTGATTATTACC
CGCAGCGCTGATGGCATGGCGCTCTATCGCAACGACCATGCCCCTGTCTTTTTGCCAACCCATGCCCGCAACGTCTACGA
TGTGACTGGAGCAGGTGATACGGTTGTAGCAATTTTGGCCTTGGCGCTAGCTAGCGGTAGCAGTTTGGAGCATGCCATGC
AATTGGCCAATCTAGCAGCCGGAATTGTGGTGGGCAAAGTTGGCACGGCTACCGTCGATCTGGCCGAATTATCGCAAGCA
GTTACCAGCCTTTATTTGTAA

Upstream 100 bases:

>100_bases
GCGGCGGTCGAAGAACAATTAGGCTTAGTTGGCCAGCCATTGAAAATCGATTATATCAAGCCCCGCCCAGCCCATGAATT
GATCGAATTGGAGATTCATT

Downstream 100 bases:

>100_bases
TGGATTATGAGGTTCGCAACCAGTTTCGCCGTACCCTCACCCCCAACCCCTCGCCCACTGTGGCGGGCGAGGGGTGTATT
TCCAGAGTGATTCCCCCTCG

Product: rfaE bifunctional protein

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MHELTATLAKLSQQRVLIVGDVMLDEYIWGDVTRISPEAPVPIVNVRSRSYRPGGASNVAASIAALNAEVLLGGVIGDDL
AGQQLKIALQQAGVADSTGLISAQRPTTLKTRIIAHNQQMLRYDSEVSTALDEASEAALCAWVDQQIANCQVCILSDYAK
GVLTERICQHVIQQARYYNIPVVVDPKGINYQRYAQASVITPNLQETQVVTGLSLQTLEQLHHAADQLLDLLQGAALIIT
RSADGMALYRNDHAPVFLPTHARNVYDVTGAGDTVVAILALALASGSSLEHAMQLANLAAGIVVGKVGTATVDLAELSQA
VTSLYL

Sequences:

>Translated_326_residues
MHELTATLAKLSQQRVLIVGDVMLDEYIWGDVTRISPEAPVPIVNVRSRSYRPGGASNVAASIAALNAEVLLGGVIGDDL
AGQQLKIALQQAGVADSTGLISAQRPTTLKTRIIAHNQQMLRYDSEVSTALDEASEAALCAWVDQQIANCQVCILSDYAK
GVLTERICQHVIQQARYYNIPVVVDPKGINYQRYAQASVITPNLQETQVVTGLSLQTLEQLHHAADQLLDLLQGAALIIT
RSADGMALYRNDHAPVFLPTHARNVYDVTGAGDTVVAILALALASGSSLEHAMQLANLAAGIVVGKVGTATVDLAELSQA
VTSLYL
>Mature_326_residues
MHELTATLAKLSQQRVLIVGDVMLDEYIWGDVTRISPEAPVPIVNVRSRSYRPGGASNVAASIAALNAEVLLGGVIGDDL
AGQQLKIALQQAGVADSTGLISAQRPTTLKTRIIAHNQQMLRYDSEVSTALDEASEAALCAWVDQQIANCQVCILSDYAK
GVLTERICQHVIQQARYYNIPVVVDPKGINYQRYAQASVITPNLQETQVVTGLSLQTLEQLHHAADQLLDLLQGAALIIT
RSADGMALYRNDHAPVFLPTHARNVYDVTGAGDTVVAILALALASGSSLEHAMQLANLAAGIVVGKVGTATVDLAELSQA
VTSLYL

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=319, Percent_Identity=43.2601880877743, Blast_Score=246, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.-

Molecular weight: Translated: 34740; Mature: 34740

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELTATLAKLSQQRVLIVGDVMLDEYIWGDVTRISPEAPVPIVNVRSRSYRPGGASNVA
CCHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCEEECCCCCCCEEECCCCCCCCCCCHHHH
ASIAALNAEVLLGGVIGDDLAGQQLKIALQQAGVADSTGLISAQRPTTLKTRIIAHNQQM
HHHHHHHHHHEEEEHHCCCCCCHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHCCHHH
LRYDSEVSTALDEASEAALCAWVDQQIANCQVCILSDYAKGVLTERICQHVIQQARYYNI
HHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCC
PVVVDPKGINYQRYAQASVITPNLQETQVVTGLSLQTLEQLHHAADQLLDLLQGAALIIT
CEEECCCCCCHHHHCCCEEECCCCCHHHEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEE
RSADGMALYRNDHAPVFLPTHARNVYDVTGAGDTVVAILALALASGSSLEHAMQLANLAA
ECCCCEEEEECCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GIVVGKVGTATVDLAELSQAVTSLYL
HHEEECCCCCEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MHELTATLAKLSQQRVLIVGDVMLDEYIWGDVTRISPEAPVPIVNVRSRSYRPGGASNVA
CCHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCEEECCCCCCCEEECCCCCCCCCCCHHHH
ASIAALNAEVLLGGVIGDDLAGQQLKIALQQAGVADSTGLISAQRPTTLKTRIIAHNQQM
HHHHHHHHHHEEEEHHCCCCCCHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHCCHHH
LRYDSEVSTALDEASEAALCAWVDQQIANCQVCILSDYAKGVLTERICQHVIQQARYYNI
HHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCC
PVVVDPKGINYQRYAQASVITPNLQETQVVTGLSLQTLEQLHHAADQLLDLLQGAALIIT
CEEECCCCCCHHHHCCCEEECCCCCHHHEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEE
RSADGMALYRNDHAPVFLPTHARNVYDVTGAGDTVVAILALALASGSSLEHAMQLANLAA
ECCCCEEEEECCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GIVVGKVGTATVDLAELSQAVTSLYL
HHEEECCCCCEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA