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The map label for this gene is aroK [H]

Identifier: 159897547

GI number: 159897547

Start: 1164919

End: 1165431

Strand: Direct

Name: aroK [H]

Synonym: Haur_1018

Alternate gene names: 159897547

Gene position: 1164919-1165431 (Clockwise)

Preceding gene: 159897546

Following gene: 159897549

Centisome position: 18.36

GC content: 47.56

Gene sequence:

>513_bases
ATGGCGCAGCATCGCAATGTGATTTTAATTGGCATGCCTGGATCGGGCAAAAGTACGCTGGGCATTTTATTAGCTAAAGC
CTTAGTTTTTGATTTTATTGATACCGATGTGGTGATTCAAACCCGCCAGCATGGCCGCTTGATTGAGATTCTCGAACGGC
TAGGCGCTGAGCAATTTTGTGCGGTCGAAAATCAATATTGCGCTGAGCTAGAGCTTGATCAATATGTGGTGGCGACTGGT
GGCAGCGTGATTTATAGCCCCGATGCTATGGCCAATTTCCAGCGGCTTGGCACAATCGTCTATCTTTCAATCGCATTCGA
TGAACTGTTGCCACGCATCACCGATATGGATTCGCGGGGAATTGTGATGCAGCCAGGCCAAAGTTTTGCCGATTTATATG
CCGAGCGCGTGCCGCTGTATCGCCAATTTGCCAATATCACCGTAGATTGCACTGGCGAAGATCATGAACACACCGTTAGC
CAAATTATGGCTGCATTAAACGCCGATAATTAA

Upstream 100 bases:

>100_bases
TCGCACCGCGCCGATCTCTCCCTGATCGCGGTGCGAGCTTTTTTGTATTTACGCTGCTTGGCGTATAATACAGCCCACGC
TTGTGTTTGGAGATTTGGCA

Downstream 100 bases:

>100_bases
TCTGGCTATGCTCAACCGTAATTGTGCCATCAGCGCCAAAGAAACGCTCGCCACTGTCAGCCGGGATCGAAAGCAGATCA
ATCGGGGCTGAGCGTTTGAT

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MAQHRNVILIGMPGSGKSTLGILLAKALVFDFIDTDVVIQTRQHGRLIEILERLGAEQFCAVENQYCAELELDQYVVATG
GSVIYSPDAMANFQRLGTIVYLSIAFDELLPRITDMDSRGIVMQPGQSFADLYAERVPLYRQFANITVDCTGEDHEHTVS
QIMAALNADN

Sequences:

>Translated_170_residues
MAQHRNVILIGMPGSGKSTLGILLAKALVFDFIDTDVVIQTRQHGRLIEILERLGAEQFCAVENQYCAELELDQYVVATG
GSVIYSPDAMANFQRLGTIVYLSIAFDELLPRITDMDSRGIVMQPGQSFADLYAERVPLYRQFANITVDCTGEDHEHTVS
QIMAALNADN
>Mature_169_residues
AQHRNVILIGMPGSGKSTLGILLAKALVFDFIDTDVVIQTRQHGRLIEILERLGAEQFCAVENQYCAELELDQYVVATGG
SVIYSPDAMANFQRLGTIVYLSIAFDELLPRITDMDSRGIVMQPGQSFADLYAERVPLYRQFANITVDCTGEDHEHTVSQ
IMAALNADN

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=173, Percent_Identity=30.0578034682081, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786587, Length=165, Percent_Identity=32.1212121212121, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 18812; Mature: 18681

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQHRNVILIGMPGSGKSTLGILLAKALVFDFIDTDVVIQTRQHGRLIEILERLGAEQFC
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCHHHH
AVENQYCAELELDQYVVATGGSVIYSPDAMANFQRLGTIVYLSIAFDELLPRITDMDSRG
HHCCCHHCCCCCCEEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IVMQPGQSFADLYAERVPLYRQFANITVDCTGEDHEHTVSQIMAALNADN
EEECCCCHHHHHHHHHCHHHHHHHCEEEEECCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AQHRNVILIGMPGSGKSTLGILLAKALVFDFIDTDVVIQTRQHGRLIEILERLGAEQFC
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCHHHH
AVENQYCAELELDQYVVATGGSVIYSPDAMANFQRLGTIVYLSIAFDELLPRITDMDSRG
HHCCCHHCCCCCCEEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IVMQPGQSFADLYAERVPLYRQFANITVDCTGEDHEHTVSQIMAALNADN
EEECCCCHHHHHHHHHCHHHHHHHCEEEEECCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA