| Definition | Herpetosiphon aurantiacus ATCC 23779 chromosome, complete genome. |
|---|---|
| Accession | NC_009972 |
| Length | 6,346,587 |
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The map label for this gene is lvr [H]
Identifier: 159897503
GI number: 159897503
Start: 1117176
End: 1117940
Strand: Direct
Name: lvr [H]
Synonym: Haur_0974
Alternate gene names: 159897503
Gene position: 1117176-1117940 (Clockwise)
Preceding gene: 159897502
Following gene: 159897504
Centisome position: 17.6
GC content: 55.82
Gene sequence:
>765_bases ATGCGTTTACACGACAACGTTGTCATCATTACCGGAGCCGCCTCAGGGATGGGCCTTGCGATGGCTACCCGCTTTGCTGC CGAAGGAGCTAAATTAGTACTTGGCGATTGGAATGCTCAGCGGCTCGAAGCAGCCGTCGCCACGATTCAAGCCAGCGGGG CCGCCGTGGTGGGTGCACAAGGGAACATTGCCGATCAAGCGACTGCCGAGGCCTTAGTTGATTTAGCCATCAGCAGCTAC GGCCAACTCGATGTGCTCTGCAACAACGCCGGGGTTATGGATTCGATGCAAGGAGTCGCCGAAGTTTCCGATGATATGTG GCGACGAGTCTTGGGCATCAATCTCGAAGGCCCGATGTTTACTAGTCGGCGGGCACTCAAATATATGTTGGAGCGTGGCA GCGGCGTGATTGTTAATGTTGCTTCGACGGCAGGAATTCATGGTGGTTCAGCTGGCGCAGCCTACACCGCCTCGAAACAT GCCTTGGTTGGCCTAACCCGTAACACCGCATGGATTTACGCCAAACGCAACATTCGCTGTAACGCAATTTGCCCAGGCGG CACGATCACCAACATCGTCGAATCGATGGATCGCAACGCGATTGCTCCAGCCGATGCTGCTCGCGTTGGCGAGTTTACTG CGCTGGCTCCGGCCTACCTCGAACCCTCGGATATTGCCAATTTGGCCTTATTCTTGGCTTCGGATGAGTCGCGGCATATC AATGGGGCAATTATTCCAGCCGATGCTGGTTGGGCCGCCGTTTAG
Upstream 100 bases:
>100_bases TGGCGCGATAACGTGAATTTACGGGGTCTCAAAGCCCTCCCTGTGATCTTCTAGATCACTTTTTCGATCAACCATTCATT CTTACCACAGGAGTCGATCA
Downstream 100 bases:
>100_bases CTAGATTATTCGCTTGGATTCAGCCCCACGCCCAACGCCTTGGACGTGGGGTTTTCGTATTGATCAGGCAATGAGTTCTG ATGCCGAAACGCTATTTGCT
Product: short-chain dehydrogenase/reductase SDR
Products: @DEHY06.txt*3-Dehydro-2- Deoxy-D-Gluconate!; NADH. [C]
Alternate protein names: (6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase [H]
Number of amino acids: Translated: 254; Mature: 254
Protein sequence:
>254_residues MRLHDNVVIITGAASGMGLAMATRFAAEGAKLVLGDWNAQRLEAAVATIQASGAAVVGAQGNIADQATAEALVDLAISSY GQLDVLCNNAGVMDSMQGVAEVSDDMWRRVLGINLEGPMFTSRRALKYMLERGSGVIVNVASTAGIHGGSAGAAYTASKH ALVGLTRNTAWIYAKRNIRCNAICPGGTITNIVESMDRNAIAPADAARVGEFTALAPAYLEPSDIANLALFLASDESRHI NGAIIPADAGWAAV
Sequences:
>Translated_254_residues MRLHDNVVIITGAASGMGLAMATRFAAEGAKLVLGDWNAQRLEAAVATIQASGAAVVGAQGNIADQATAEALVDLAISSY GQLDVLCNNAGVMDSMQGVAEVSDDMWRRVLGINLEGPMFTSRRALKYMLERGSGVIVNVASTAGIHGGSAGAAYTASKH ALVGLTRNTAWIYAKRNIRCNAICPGGTITNIVESMDRNAIAPADAARVGEFTALAPAYLEPSDIANLALFLASDESRHI NGAIIPADAGWAAV >Mature_254_residues MRLHDNVVIITGAASGMGLAMATRFAAEGAKLVLGDWNAQRLEAAVATIQASGAAVVGAQGNIADQATAEALVDLAISSY GQLDVLCNNAGVMDSMQGVAEVSDDMWRRVLGINLEGPMFTSRRALKYMLERGSGVIVNVASTAGIHGGSAGAAYTASKH ALVGLTRNTAWIYAKRNIRCNAICPGGTITNIVESMDRNAIAPADAARVGEFTALAPAYLEPSDIANLALFLASDESRHI NGAIIPADAGWAAV
Specific function: Catalyzes the regio- and stereoselective reversible NAD- dependent reduction of (6R)-2,2,6-trimethyl-1,4-cyclohexanedione (levodione) to (4R,6R)-4-hydroxy-2,2,6-trimethylcyclohexanone (actinol) [H]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=30.8641975308642, Blast_Score=123, Evalue=2e-28, Organism=Homo sapiens, GI5031737, Length=256, Percent_Identity=30.859375, Blast_Score=109, Evalue=2e-24, Organism=Homo sapiens, GI31542939, Length=257, Percent_Identity=32.295719844358, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=32.0441988950276, Blast_Score=104, Evalue=8e-23, Organism=Homo sapiens, GI4504505, Length=262, Percent_Identity=30.5343511450382, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI33667109, Length=184, Percent_Identity=33.1521739130435, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI15277342, Length=261, Percent_Identity=26.4367816091954, Blast_Score=95, Evalue=7e-20, Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=29.7619047619048, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=26.8774703557312, Blast_Score=88, Evalue=6e-18, Organism=Homo sapiens, GI224922801, Length=178, Percent_Identity=33.1460674157303, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=28, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI7706318, Length=200, Percent_Identity=31.5, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI20149619, Length=215, Percent_Identity=33.0232558139535, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI10190704, Length=257, Percent_Identity=29.1828793774319, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI19923817, Length=267, Percent_Identity=25.0936329588015, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI40807363, Length=193, Percent_Identity=26.9430051813472, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=31.0077519379845, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI59889578, Length=211, Percent_Identity=26.5402843601896, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI157739938, Length=169, Percent_Identity=31.3609467455621, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI302344755, Length=109, Percent_Identity=32.1100917431193, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI142976729, Length=225, Percent_Identity=28, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI83715985, Length=172, Percent_Identity=33.1395348837209, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI210032110, Length=185, Percent_Identity=29.1891891891892, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI25282469, Length=210, Percent_Identity=28.0952380952381, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=32.6771653543307, Blast_Score=119, Evalue=3e-28, Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=29.3877551020408, Blast_Score=111, Evalue=5e-26, Organism=Escherichia coli, GI87082100, Length=247, Percent_Identity=34.0080971659919, Blast_Score=111, Evalue=5e-26, Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=32.6771653543307, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1787335, Length=256, Percent_Identity=28.515625, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=29.0836653386454, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI1787526, Length=254, Percent_Identity=29.1338582677165, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=28.8537549407115, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=29.5275590551181, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=25.1012145748988, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1788891, Length=260, Percent_Identity=28.4615384615385, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=27.2222222222222, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI2367365, Length=251, Percent_Identity=29.8804780876494, Blast_Score=72, Evalue=5e-14, Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=30.2788844621514, Blast_Score=66, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17561402, Length=246, Percent_Identity=32.520325203252, Blast_Score=122, Evalue=1e-28, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=26.5873015873016, Blast_Score=110, Evalue=8e-25, Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=32.9545454545455, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=33.5849056603774, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=32.3308270676692, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=31.7164179104478, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=32.5757575757576, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17555706, Length=252, Percent_Identity=29.7619047619048, Blast_Score=99, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17568967, Length=262, Percent_Identity=29.0076335877863, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562904, Length=274, Percent_Identity=31.7518248175182, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI193203117, Length=187, Percent_Identity=31.5508021390374, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI193203115, Length=180, Percent_Identity=32.7777777777778, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=30.8550185873606, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=30.0380228136882, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=30.3703703703704, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=30.8270676691729, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=30.1020408163265, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=28.4090909090909, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=27.9527559055118, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=28.1368821292776, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=27.0676691729323, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=28.968253968254, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=29.7397769516729, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=25.3012048192771, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17538480, Length=272, Percent_Identity=30.1470588235294, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=26.3157894736842, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=29.1044776119403, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17567345, Length=161, Percent_Identity=34.7826086956522, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17564282, Length=181, Percent_Identity=28.1767955801105, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17538182, Length=207, Percent_Identity=31.8840579710145, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17562910, Length=281, Percent_Identity=27.0462633451957, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17551412, Length=277, Percent_Identity=28.5198555956679, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17536651, Length=264, Percent_Identity=26.1363636363636, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=260, Percent_Identity=30.3846153846154, Blast_Score=107, Evalue=2e-24, Organism=Saccharomyces cerevisiae, GI6323882, Length=190, Percent_Identity=28.9473684210526, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=8e-27, Organism=Drosophila melanogaster, GI24644339, Length=262, Percent_Identity=32.824427480916, Blast_Score=107, Evalue=8e-24, Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=27.2727272727273, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI18859837, Length=263, Percent_Identity=29.6577946768061, Blast_Score=100, Evalue=8e-22, Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=29.296875, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=28.90625, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=27.6264591439689, Blast_Score=81, Evalue=5e-16, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=28.7179487179487, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI17737361, Length=262, Percent_Identity=29.7709923664122, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI221510726, Length=234, Percent_Identity=27.3504273504274, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24640492, Length=186, Percent_Identity=29.5698924731183, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI221331218, Length=200, Percent_Identity=25, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24665243, Length=200, Percent_Identity=25, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI161076933, Length=201, Percent_Identity=26.865671641791, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24584748, Length=201, Percent_Identity=26.865671641791, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=26.8, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24644337, Length=247, Percent_Identity=29.9595141700405, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI221331216, Length=201, Percent_Identity=25.3731343283582, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24665247, Length=201, Percent_Identity=25.3731343283582, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI116007236, Length=204, Percent_Identity=28.4313725490196, Blast_Score=66, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.125 [C]
Molecular weight: Translated: 26254; Mature: 26254
Theoretical pI: Translated: 5.26; Mature: 5.26
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 4.7 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 3.5 %Met (Mature Protein) 4.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRLHDNVVIITGAASGMGLAMATRFAAEGAKLVLGDWNAQRLEAAVATIQASGAAVVGAQ CEECCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHEECCCEEEEECC GNIADQATAEALVDLAISSYGQLDVLCNNAGVMDSMQGVAEVSDDMWRRVLGINLEGPMF CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC TSRRALKYMLERGSGVIVNVASTAGIHGGSAGAAYTASKHALVGLTRNTAWIYAKRNIRC HHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEECCCCEEEEEECCEEEEEEECCEEE NAICPGGTITNIVESMDRNAIAPADAARVGEFTALAPAYLEPSDIANLALFLASDESRHI EEECCCCHHHHHHHHHCCCCCCCCCHHHCCCHHCCCCCCCCCHHHCEEEEEEECCCCCCC NGAIIPADAGWAAV CCEEEECCCCCCCC >Mature Secondary Structure MRLHDNVVIITGAASGMGLAMATRFAAEGAKLVLGDWNAQRLEAAVATIQASGAAVVGAQ CEECCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHEECCCEEEEECC GNIADQATAEALVDLAISSYGQLDVLCNNAGVMDSMQGVAEVSDDMWRRVLGINLEGPMF CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC TSRRALKYMLERGSGVIVNVASTAGIHGGSAGAAYTASKHALVGLTRNTAWIYAKRNIRC HHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEECCCCEEEEEECCEEEEEEECCEEE NAICPGGTITNIVESMDRNAIAPADAARVGEFTALAPAYLEPSDIANLALFLASDESRHI EEECCCCHHHHHHHHHCCCCCCCCCHHHCCCHHCCCCCCCCCHHHCEEEEEEECCCCCCC NGAIIPADAGWAAV CCEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NAD+ [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 15.4 {2-deoxygluconate}} [C]
Substrates: @DEOX03.txt*2-Deoxy-D-Gluconate!; NAD(+) [C]
Specific reaction: @DEOX03.txt*2-Deoxy-D-Gluconate! + NAD(+) = @DEHY06.txt*3-Dehydro-2- Deoxy-D-Gluconate! + NADH. [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11388460; 10508066 [H]