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The map label for this gene is pksS [H]

Identifier: 159897502

GI number: 159897502

Start: 1115891

End: 1117129

Strand: Direct

Name: pksS [H]

Synonym: Haur_0973

Alternate gene names: 159897502

Gene position: 1115891-1117129 (Clockwise)

Preceding gene: 159897501

Following gene: 159897503

Centisome position: 17.58

GC content: 53.03

Gene sequence:

>1239_bases
ATGACACAATCACAAGTGCACATATATGCCGATGATCCAACGGCGCAGATTTTTCAGTCCAGCGCAATTGAAAATCCGTA
TCCGTTGTTTGCCCAAATGCGGGCCAAAGCGGCGGTGCTGGCGGTTCCCTCGCCCTATGAATTTGTCAAAGCCGATGCGT
GGCTGGTAACGCGCTATGCCGAAGCAGTCCAAGTATTAAAGGATAGCCGCTTCACGGTCGATGCAACGATCCTCAACCCT
GAGGCTGGCGTATTTGGCCAAACTGCCTCGGAAGGAGCCGAAGATCGCAGCTTCTTGGGCGCAAAATCGATGGTTAGCGC
CGATGGAGCCGAACACTCGCGCTTACGCAGTTTGGTGGCCAAAGCCTTTACCCCGCGCTATATCGAACAGCTGCGCCCAC
GCATCCAAGAGCTTGCCGATGAATTGCTTGATCAGGTGCAGGCTCACGGCACGATGGATTTGGTGCAAGATTACGCCTAT
CCTTTGCCAATTAACGTTATCTCCGAAATGCTGGGCGTACCAACCCATGAACGCGACCAGATGCGCGAATGGTCGGACGC
ATTGACCAGCCATAGCCCTGAAAGCCAAGGCCAGTTGCGCGAATTTGCCATGTATGTGCAAAAGCTGATCGCTGATAAAC
GCCGCAATCCGCAAGCTGATCTGATTAGTAAATTGGTCGAGTTGGAAGCCACAGGCGATGCCCTCAGCGAATCAGAATTA
TTGGCAACCGCAGGCTTGTTAATTTTTGCGGGCCACGAAACCACCTCGAATTTAATCAGCATTGGCTCGTTGATGTTGCT
TGATCATCCTGAGCAACGCGCTCGCTTGCAAGCCGATCCCAGCCTTATTCCAACAGCCGTCGAAGAATTATTGCGCTTCA
ATGGGCCAATCTTTAGCCCTGCCCCACGTTTTGCGCTCGAAGATGTGGAGATCGCAGGTCAGCCGATTCGCCGTGGCGAT
TTGGTGTTGGTGGCGCTTGGCTCGGCCAACCACGATCAAAGCGTTTTCAACGATCCTGAATCATTGGATGTGGCGCGTGA
AATTAGCCGCCAACTCGCTTTTGGCCATGGCGTGCACTTCTGTTTGGGTGCGCCGCTCGCTCGCTTAGAAGCTGAAATCG
CTTTCACCAGCTTATTGAAACGCATGCCCAACTTACAGTTAGCTGTGCCACGCGAACACATTCAGTGGCGCGATAACGTG
AATTTACGGGGTCTCAAAGCCCTCCCTGTGATCTTCTAG

Upstream 100 bases:

>100_bases
GCCCTGCCGACTTGATTCCCCATATTAGCCAGATCTTCTTTCGCGGCATTGTCGCACCAACTGGAAGTTAAGTTAATTGA
TAGCAAGGAATCATACAACA

Downstream 100 bases:

>100_bases
ATCACTTTTTCGATCAACCATTCATTCTTACCACAGGAGTCGATCAATGCGTTTACACGACAACGTTGTCATCATTACCG
GAGCCGCCTCAGGGATGGGC

Product: cytochrome P450

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MTQSQVHIYADDPTAQIFQSSAIENPYPLFAQMRAKAAVLAVPSPYEFVKADAWLVTRYAEAVQVLKDSRFTVDATILNP
EAGVFGQTASEGAEDRSFLGAKSMVSADGAEHSRLRSLVAKAFTPRYIEQLRPRIQELADELLDQVQAHGTMDLVQDYAY
PLPINVISEMLGVPTHERDQMREWSDALTSHSPESQGQLREFAMYVQKLIADKRRNPQADLISKLVELEATGDALSESEL
LATAGLLIFAGHETTSNLISIGSLMLLDHPEQRARLQADPSLIPTAVEELLRFNGPIFSPAPRFALEDVEIAGQPIRRGD
LVLVALGSANHDQSVFNDPESLDVAREISRQLAFGHGVHFCLGAPLARLEAEIAFTSLLKRMPNLQLAVPREHIQWRDNV
NLRGLKALPVIF

Sequences:

>Translated_412_residues
MTQSQVHIYADDPTAQIFQSSAIENPYPLFAQMRAKAAVLAVPSPYEFVKADAWLVTRYAEAVQVLKDSRFTVDATILNP
EAGVFGQTASEGAEDRSFLGAKSMVSADGAEHSRLRSLVAKAFTPRYIEQLRPRIQELADELLDQVQAHGTMDLVQDYAY
PLPINVISEMLGVPTHERDQMREWSDALTSHSPESQGQLREFAMYVQKLIADKRRNPQADLISKLVELEATGDALSESEL
LATAGLLIFAGHETTSNLISIGSLMLLDHPEQRARLQADPSLIPTAVEELLRFNGPIFSPAPRFALEDVEIAGQPIRRGD
LVLVALGSANHDQSVFNDPESLDVAREISRQLAFGHGVHFCLGAPLARLEAEIAFTSLLKRMPNLQLAVPREHIQWRDNV
NLRGLKALPVIF
>Mature_411_residues
TQSQVHIYADDPTAQIFQSSAIENPYPLFAQMRAKAAVLAVPSPYEFVKADAWLVTRYAEAVQVLKDSRFTVDATILNPE
AGVFGQTASEGAEDRSFLGAKSMVSADGAEHSRLRSLVAKAFTPRYIEQLRPRIQELADELLDQVQAHGTMDLVQDYAYP
LPINVISEMLGVPTHERDQMREWSDALTSHSPESQGQLREFAMYVQKLIADKRRNPQADLISKLVELEATGDALSESELL
ATAGLLIFAGHETTSNLISIGSLMLLDHPEQRARLQADPSLIPTAVEELLRFNGPIFSPAPRFALEDVEIAGQPIRRGDL
VLVALGSANHDQSVFNDPESLDVAREISRQLAFGHGVHFCLGAPLARLEAEIAFTSLLKRMPNLQLAVPREHIQWRDNVN
LRGLKALPVIF

Specific function: Involved in the metabolism of the antibiotic polyketide bacillaene which is involved in secondary metabolism. The substrate is dihydrobacillaene [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI310125128, Length=178, Percent_Identity=32.0224719101124, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI14550409, Length=178, Percent_Identity=32.0224719101124, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI310125130, Length=178, Percent_Identity=32.0224719101124, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI190570174, Length=178, Percent_Identity=32.0224719101124, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 45547; Mature: 45416

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSQVHIYADDPTAQIFQSSAIENPYPLFAQMRAKAAVLAVPSPYEFVKADAWLVTRYA
CCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHH
EAVQVLKDSRFTVDATILNPEAGVFGQTASEGAEDRSFLGAKSMVSADGAEHSRLRSLVA
HHHHHHHCCCEEEEEEEECCCCCCCCCCHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
KAFTPRYIEQLRPRIQELADELLDQVQAHGTMDLVQDYAYPLPINVISEMLGVPTHERDQ
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHCCCCCCHHH
MREWSDALTSHSPESQGQLREFAMYVQKLIADKRRNPQADLISKLVELEATGDALSESEL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHH
LATAGLLIFAGHETTSNLISIGSLMLLDHPEQRARLQADPSLIPTAVEELLRFNGPIFSP
HHHHCEEEEECCCCHHHHHHHHHHHEECCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCC
APRFALEDVEIAGQPIRRGDLVLVALGSANHDQSVFNDPESLDVAREISRQLAFGHGVHF
CCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCHHH
CLGAPLARLEAEIAFTSLLKRMPNLQLAVPREHIQWRDNVNLRGLKALPVIF
HHCCCHHHHHHHHHHHHHHHHCCCCEEECCHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TQSQVHIYADDPTAQIFQSSAIENPYPLFAQMRAKAAVLAVPSPYEFVKADAWLVTRYA
CCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHH
EAVQVLKDSRFTVDATILNPEAGVFGQTASEGAEDRSFLGAKSMVSADGAEHSRLRSLVA
HHHHHHHCCCEEEEEEEECCCCCCCCCCHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
KAFTPRYIEQLRPRIQELADELLDQVQAHGTMDLVQDYAYPLPINVISEMLGVPTHERDQ
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHCCCCCCHHH
MREWSDALTSHSPESQGQLREFAMYVQKLIADKRRNPQADLISKLVELEATGDALSESEL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHH
LATAGLLIFAGHETTSNLISIGSLMLLDHPEQRARLQADPSLIPTAVEELLRFNGPIFSP
HHHHCEEEEECCCCHHHHHHHHHHHEECCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCC
APRFALEDVEIAGQPIRRGDLVLVALGSANHDQSVFNDPESLDVAREISRQLAFGHGVHF
CCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCHHH
CLGAPLARLEAEIAFTSLLKRMPNLQLAVPREHIQWRDNVNLRGLKALPVIF
HHCCCHHHHHHHHHHHHHHHHCCCCEEECCHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]