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The map label for this gene is purN [H]

Identifier: 159897474

GI number: 159897474

Start: 1081793

End: 1082413

Strand: Reverse

Name: purN [H]

Synonym: Haur_0945

Alternate gene names: 159897474

Gene position: 1082413-1081793 (Counterclockwise)

Preceding gene: 159897475

Following gene: 159897473

Centisome position: 17.06

GC content: 52.01

Gene sequence:

>621_bases
ATGATGCGGCTTGCCGTGATGGTATCGGGCAGTGGCTCCAATTTACAAGCCTTGATCGATGCTCAAAAATCGCACCAACT
CAACGCCACAATCAAGGTGGTGATTTGCGACCAACCCAAAGCCCAAGCGATTAGTCGCACCTTGGAAGCACGGATTCCAG
TGATCTGTGTGCCATTGGCAAAAAAAGCCAGCCGCGAGCAATGGGCCGCCCAAATTAGCGAATTACTGGCCGCTTTCAAA
CCCGATTTAGTTGTGATGGCAGGCTGGATGCGGGTAATGCCAGCCTCGTTTGTTGAACGCTGGACACCGAATATTATCAA
TCAGCACCCAGCTTTGTTGCCCCACGATGGCGGCGAATGCTATACGCTCAGCGATGGCCGCCAAATTCCGGCGATTCGCG
GGGCGCATGCAGTACGCGATGCCTTGGCGCTGGGCGTGCCAGTTACTGGTTGCACGGTGCATCAAATTACGCCAATCGTT
GATGTTGGCCCCGTTTTGGCGCAAGTTGAAGTTGCGGTCTTGCCCGACGATGATCAAGACAGTTTGCACGAACGAATCAA
ACAAGCTGAACGACGGATTTTAGTTGAAGTAATTAACAATTTAGCCCAAACAGTTGCCTAA

Upstream 100 bases:

>100_bases
CATTGCGCGAAGCCCGCGATAAAGCCTACGCCGCAACCGAATTGGTCGAATTTGCTGGCAAATATCAACGCAGCGATATC
GCCGCACGGGGGTTAGCAGA

Downstream 100 bases:

>100_bases
ATTCCGCCCTAGCCGTAGTAATTTCCGCTGGCACTCTTGCCTGCTACGGCTAGCGCTATTCTGTGGGAGATATGTCAATG
ACGACAACAGCAGAAAAAAT

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MMRLAVMVSGSGSNLQALIDAQKSHQLNATIKVVICDQPKAQAISRTLEARIPVICVPLAKKASREQWAAQISELLAAFK
PDLVVMAGWMRVMPASFVERWTPNIINQHPALLPHDGGECYTLSDGRQIPAIRGAHAVRDALALGVPVTGCTVHQITPIV
DVGPVLAQVEVAVLPDDDQDSLHERIKQAERRILVEVINNLAQTVA

Sequences:

>Translated_206_residues
MMRLAVMVSGSGSNLQALIDAQKSHQLNATIKVVICDQPKAQAISRTLEARIPVICVPLAKKASREQWAAQISELLAAFK
PDLVVMAGWMRVMPASFVERWTPNIINQHPALLPHDGGECYTLSDGRQIPAIRGAHAVRDALALGVPVTGCTVHQITPIV
DVGPVLAQVEVAVLPDDDQDSLHERIKQAERRILVEVINNLAQTVA
>Mature_206_residues
MMRLAVMVSGSGSNLQALIDAQKSHQLNATIKVVICDQPKAQAISRTLEARIPVICVPLAKKASREQWAAQISELLAAFK
PDLVVMAGWMRVMPASFVERWTPNIINQHPALLPHDGGECYTLSDGRQIPAIRGAHAVRDALALGVPVTGCTVHQITPIV
DVGPVLAQVEVAVLPDDDQDSLHERIKQAERRILVEVINNLAQTVA

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=192, Percent_Identity=34.8958333333333, Blast_Score=121, Evalue=5e-28,
Organism=Homo sapiens, GI209869995, Length=192, Percent_Identity=34.8958333333333, Blast_Score=121, Evalue=5e-28,
Organism=Homo sapiens, GI209869993, Length=192, Percent_Identity=34.8958333333333, Blast_Score=121, Evalue=5e-28,
Organism=Escherichia coli, GI1788846, Length=201, Percent_Identity=32.3383084577114, Blast_Score=113, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17567511, Length=193, Percent_Identity=30.5699481865285, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320616, Length=225, Percent_Identity=31.1111111111111, Blast_Score=89, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24582400, Length=206, Percent_Identity=37.8640776699029, Blast_Score=134, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 22336; Mature: 22336

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRLAVMVSGSGSNLQALIDAQKSHQLNATIKVVICDQPKAQAISRTLEARIPVICVPLA
CEEEEEEEECCCCCHHHHHCCHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCEEEECCC
KKASREQWAAQISELLAAFKPDLVVMAGWMRVMPASFVERWTPNIINQHPALLPHDGGEC
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCE
YTLSDGRQIPAIRGAHAVRDALALGVPVTGCTVHQITPIVDVGPVLAQVEVAVLPDDDQD
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHCCHHHHEEEEEEECCCCHH
SLHERIKQAERRILVEVINNLAQTVA
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMRLAVMVSGSGSNLQALIDAQKSHQLNATIKVVICDQPKAQAISRTLEARIPVICVPLA
CEEEEEEEECCCCCHHHHHCCHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCEEEECCC
KKASREQWAAQISELLAAFKPDLVVMAGWMRVMPASFVERWTPNIINQHPALLPHDGGEC
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCE
YTLSDGRQIPAIRGAHAVRDALALGVPVTGCTVHQITPIVDVGPVLAQVEVAVLPDDDQD
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHCCHHHHEEEEEEECCCCHH
SLHERIKQAERRILVEVINNLAQTVA
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3301838; 9205837; 9278503; 10954745; 2204419; 1522592; 1631098; 9698564; 10606510 [H]