BacMap

Definition	Herpetosiphon aurantiacus ATCC 23779 chromosome, complete genome.
Accession	NC_009972
Length	6,346,587

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The map label for this gene is paaF [C]

Identifier: 159897368

GI number: 159897368

Start: 950266

End: 951057

Strand: Reverse

Name: paaF [C]

Synonym: Haur_0839

Alternate gene names: 159897368

Gene position: 951057-950266 (Counterclockwise)

Preceding gene: 159897369

Following gene: 159897364

Centisome position: 14.99

GC content: 54.42

Gene sequence:

>792_bases
GTGAGTGGTTTAGTCACAACTGAACAAACTGGCGCGATTTTTCGCATTACCCTCAATCGGCCCGAAAAGCGCAATGCGAT
TAGTTGGCAAGTTGGCCAGGATTTACGCGCGGCGATCGATCAGGCTGCCAGTGCCTCGGGCGTGCGGGTAGTTGTGTTGA
GCGGAGCAGGCTCGGTCTTTTCGGCAGGCATCGATCTTGGCGATTTGATGGATTTGCCCAATCGTTATGGTGAGCACTGG
TTGCGCCAAATGCGCACGATCACCGACGATTGGCAAGCCTTGACCACTCGCCTCGAACGTTTGGAAATTCCTACTATCGC
TGCCTTGCATGGCATGTGCCTTGGTTTGGGCTTGGAAATCGCCTTAGCCTGCGATTTTCGGATTGCTGCTCAAGGCACGA
AATTGGCCTTGCCTGAAACTCGCTTGGGCATTGTGCCCGATGTTGGCGGTACAACCCGTTTAACCCGTTTGGTCGGGGTT
GGTCGCGCCAAAGAATTGATTATGACAGGCCGAACCTTCAGCGCCACCGATGCCGAGCGCTGGGGAGTTGTCAATCAATT
GGCTGATGCTGATGATTTAAATACCGTGGTACAAGCGTTTGCCGATGAGCTGATTTTGGCAGCGCCATTGGCCGTTGGCA
TGGCCAAACGAGTGATTGATGGCATGTTTGATGTCGATCGGGGCTTGTTGCTCGAAGGTTGGGCGCAAAGCCAATTGATT
CGCACCGCCGATTTTAGCGAGGGTGTGCAAGCAGCAATCGCCCGCCGCGCCGCCGAATTTAAGGGCGAGTAA

Upstream 100 bases:

>100_bases
CTTTTACGGCGGCAATCGCCACGCCACAGCTGAAGCATAAGCGGTACAATCGACGTTGCATCAACGATGCAGCGTCTTTT
TTTGTGCAAAGGAGCATGCT

Downstream 100 bases:

>100_bases
AACTAGGGGATGCGGCTATAGGCTGAAGGCTTTTGACTAACGGAACATTTTTTGGATTTTCTAATAAGTTCCCAATCCAA
AAGATGTAATGGCTCATTAG

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSGLVTTEQTGAIFRITLNRPEKRNAISWQVGQDLRAAIDQAASASGVRVVVLSGAGSVFSAGIDLGDLMDLPNRYGEHW
LRQMRTITDDWQALTTRLERLEIPTIAALHGMCLGLGLEIALACDFRIAAQGTKLALPETRLGIVPDVGGTTRLTRLVGV
GRAKELIMTGRTFSATDAERWGVVNQLADADDLNTVVQAFADELILAAPLAVGMAKRVIDGMFDVDRGLLLEGWAQSQLI
RTADFSEGVQAAIARRAAEFKGE

Sequences:

>Translated_263_residues
MSGLVTTEQTGAIFRITLNRPEKRNAISWQVGQDLRAAIDQAASASGVRVVVLSGAGSVFSAGIDLGDLMDLPNRYGEHW
LRQMRTITDDWQALTTRLERLEIPTIAALHGMCLGLGLEIALACDFRIAAQGTKLALPETRLGIVPDVGGTTRLTRLVGV
GRAKELIMTGRTFSATDAERWGVVNQLADADDLNTVVQAFADELILAAPLAVGMAKRVIDGMFDVDRGLLLEGWAQSQLI
RTADFSEGVQAAIARRAAEFKGE
>Mature_262_residues
SGLVTTEQTGAIFRITLNRPEKRNAISWQVGQDLRAAIDQAASASGVRVVVLSGAGSVFSAGIDLGDLMDLPNRYGEHWL
RQMRTITDDWQALTTRLERLEIPTIAALHGMCLGLGLEIALACDFRIAAQGTKLALPETRLGIVPDVGGTTRLTRLVGVG
RAKELIMTGRTFSATDAERWGVVNQLADADDLNTVVQAFADELILAAPLAVGMAKRVIDGMFDVDRGLLLEGWAQSQLIR
TADFSEGVQAAIARRAAEFKGE

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=250, Percent_Identity=31.2, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI4502327, Length=263, Percent_Identity=33.4600760456274, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI70995211, Length=263, Percent_Identity=30.4182509505703, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI20127408, Length=183, Percent_Identity=31.1475409836066, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI68989263, Length=174, Percent_Identity=32.183908045977, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI150378541, Length=258, Percent_Identity=30.2325581395349, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI31542718, Length=260, Percent_Identity=23.4615384615385, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI37594469, Length=241, Percent_Identity=25.3112033195021, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI37594471, Length=242, Percent_Identity=25.6198347107438, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI213417737, Length=227, Percent_Identity=26.431718061674, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI157694516, Length=227, Percent_Identity=26.431718061674, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI25453481, Length=173, Percent_Identity=27.1676300578035, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI51538573, Length=173, Percent_Identity=27.1676300578035, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4757966, Length=173, Percent_Identity=27.1676300578035, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI51538581, Length=173, Percent_Identity=27.1676300578035, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4757968, Length=176, Percent_Identity=25.5681818181818, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI49355787, Length=176, Percent_Identity=25.5681818181818, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI221136756, Length=227, Percent_Identity=24.2290748898678, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI221136753, Length=227, Percent_Identity=24.2290748898678, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI221307494, Length=227, Percent_Identity=24.2290748898678, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI45643119, Length=220, Percent_Identity=25, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI260275230, Length=220, Percent_Identity=25, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI260274832, Length=220, Percent_Identity=25, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI261878539, Length=87, Percent_Identity=37.9310344827586, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787659, Length=264, Percent_Identity=32.9545454545455, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI221142681, Length=224, Percent_Identity=34.375, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787660, Length=265, Percent_Identity=31.3207547169811, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788682, Length=174, Percent_Identity=36.7816091954023, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1790281, Length=184, Percent_Identity=30.9782608695652, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788597, Length=264, Percent_Identity=26.5151515151515, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87082183, Length=255, Percent_Identity=26.2745098039216, Blast_Score=74, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17540714, Length=227, Percent_Identity=34.8017621145374, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17536985, Length=274, Percent_Identity=27.3722627737226, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17534483, Length=265, Percent_Identity=30.188679245283, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17560910, Length=186, Percent_Identity=32.258064516129, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17554946, Length=250, Percent_Identity=27.2, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI25145438, Length=268, Percent_Identity=27.9850746268657, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25144276, Length=232, Percent_Identity=30.1724137931034, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17508951, Length=232, Percent_Identity=30.1724137931034, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17508953, Length=232, Percent_Identity=30.1724137931034, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17558304, Length=247, Percent_Identity=29.9595141700405, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17549921, Length=270, Percent_Identity=25.5555555555556, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25141363, Length=178, Percent_Identity=28.6516853932584, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25144157, Length=183, Percent_Identity=28.9617486338798, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25144160, Length=183, Percent_Identity=28.9617486338798, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17535521, Length=220, Percent_Identity=23.1818181818182, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320241, Length=198, Percent_Identity=25.7575757575758, Blast_Score=86, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24653139, Length=255, Percent_Identity=36.4705882352941, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI20129971, Length=250, Percent_Identity=31.6, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24653477, Length=250, Percent_Identity=31.6, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI19920382, Length=212, Percent_Identity=33.4905660377358, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24650670, Length=183, Percent_Identity=34.4262295081967, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24583077, Length=187, Percent_Identity=35.2941176470588, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24583079, Length=187, Percent_Identity=35.2941176470588, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19921000, Length=187, Percent_Identity=35.2941176470588, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24654903, Length=190, Percent_Identity=24.7368421052632, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357171, Length=183, Percent_Identity=28.9617486338798, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19922422, Length=265, Percent_Identity=20, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583165, Length=214, Percent_Identity=26.1682242990654, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI19921018, Length=211, Percent_Identity=24.6445497630332, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28301; Mature: 28170

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLVTTEQTGAIFRITLNRPEKRNAISWQVGQDLRAAIDQAASASGVRVVVLSGAGSVF
CCCCCCCCCCCEEEEEEECCCCCCCCEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCHH
SAGIDLGDLMDLPNRYGEHWLRQMRTITDDWQALTTRLERLEIPTIAALHGMCLGLGLEI
HCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEE
ALACDFRIAAQGTKLALPETRLGIVPDVGGTTRLTRLVGVGRAKELIMTGRTFSATDAER
EEEECEEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHEECCCCCCCCHHH
WGVVNQLADADDLNTVVQAFADELILAAPLAVGMAKRVIDGMFDVDRGLLLEGWAQSQLI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHH
RTADFSEGVQAAIARRAAEFKGE
HHCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SGLVTTEQTGAIFRITLNRPEKRNAISWQVGQDLRAAIDQAASASGVRVVVLSGAGSVF
CCCCCCCCCCEEEEEEECCCCCCCCEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCHH
SAGIDLGDLMDLPNRYGEHWLRQMRTITDDWQALTTRLERLEIPTIAALHGMCLGLGLEI
HCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEE
ALACDFRIAAQGTKLALPETRLGIVPDVGGTTRLTRLVGVGRAKELIMTGRTFSATDAER
EEEECEEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHEECCCCCCCCHHH
WGVVNQLADADDLNTVVQAFADELILAAPLAVGMAKRVIDGMFDVDRGLLLEGWAQSQLI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHH
RTADFSEGVQAAIARRAAEFKGE
HHCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA