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The map label for this gene is sphR [H]

Identifier: 159897333

GI number: 159897333

Start: 908797

End: 909507

Strand: Reverse

Name: sphR [H]

Synonym: Haur_0804

Alternate gene names: 159897333

Gene position: 909507-908797 (Counterclockwise)

Preceding gene: 159897334

Following gene: 159897332

Centisome position: 14.33

GC content: 50.63

Gene sequence:

>711_bases
ATGTCCACAATATTGCTTGTAGAAGATGAAGCCCTGCTCGCCGATACGCTCCGTTACAACCTTGAACGCGAAGGCTACAC
CGTGCTTTCTGCTTCCGATGGAGTTACCGGGCTGGATTTAGCCCGCGCCGAACAGCCCGATTTGCTGATTTTAGATGTGA
TGTTGCCCAAACTCGACGGCTTTTCAGTCTGTCGAATTTTACGGCGTGAAACCAATATCCCGATTATGATGCTGACTGCC
CGCCAAGATGAAGTTGATCGGATCGCTGGCTTGGAATTGGGCGCTGATGATTATGTGATTAAGCCATTTAGCCTTGGTGA
ATTACTGGCCCGCGTTCGAGCGATTTTGCGTCGTACCGACCGCCAACCAACCGGAGTTGAACGCGAATTGCTGACCGCCG
CCAATCTTAAGGTCGATACTGGCAGTCGTCGGGTGTTTCGTGATAACAACGAAATTACGCTCGCTCAGAAGGAATTCGAC
TTGTTGGTGTGTTTGATGCGCAACCGTGGCATGGCGCTTTCGCGCGATTTGCTGCTCGAACGAGTTTGGGGTTACGATTT
TCCAGGCGATTCGCGCACGGTCGATGTGCATGTGCGTTGGCTGCGTGAGAAAGTTGAAGTAGACCCCAGCAACCCAATTT
ATATTCAAACTGTGCGTGGGATTGGCTATCGTTTTAATGATCAACTTAGCCGTAGCGAGCGCAAAAACTAA

Upstream 100 bases:

>100_bases
TCGTGGATCAATCTGCATATCTCATACTTACGATAATGGTACAATAGCAGCGGGCATTCGCCCCTTGCTGATTGTATATA
CCCAATGGTGCTGACAATCT

Downstream 100 bases:

>100_bases
TGACTTGGATTGTGTTGTTGGCGTTGACAACGATGATCGCGTTGCTTTGGGGTTGGCGTGGTCAACGCAATCTCCGCCGT
GAACTGGCCTATTTACGCAA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSTILLVEDEALLADTLRYNLEREGYTVLSASDGVTGLDLARAEQPDLLILDVMLPKLDGFSVCRILRRETNIPIMMLTA
RQDEVDRIAGLELGADDYVIKPFSLGELLARVRAILRRTDRQPTGVERELLTAANLKVDTGSRRVFRDNNEITLAQKEFD
LLVCLMRNRGMALSRDLLLERVWGYDFPGDSRTVDVHVRWLREKVEVDPSNPIYIQTVRGIGYRFNDQLSRSERKN

Sequences:

>Translated_236_residues
MSTILLVEDEALLADTLRYNLEREGYTVLSASDGVTGLDLARAEQPDLLILDVMLPKLDGFSVCRILRRETNIPIMMLTA
RQDEVDRIAGLELGADDYVIKPFSLGELLARVRAILRRTDRQPTGVERELLTAANLKVDTGSRRVFRDNNEITLAQKEFD
LLVCLMRNRGMALSRDLLLERVWGYDFPGDSRTVDVHVRWLREKVEVDPSNPIYIQTVRGIGYRFNDQLSRSERKN
>Mature_235_residues
STILLVEDEALLADTLRYNLEREGYTVLSASDGVTGLDLARAEQPDLLILDVMLPKLDGFSVCRILRRETNIPIMMLTAR
QDEVDRIAGLELGADDYVIKPFSLGELLARVRAILRRTDRQPTGVERELLTAANLKVDTGSRRVFRDNNEITLAQKEFDL
LVCLMRNRGMALSRDLLLERVWGYDFPGDSRTVDVHVRWLREKVEVDPSNPIYIQTVRGIGYRFNDQLSRSERKN

Specific function: Member of the two-component regulatory system sphR/sphS. Response regulator. Involved in inducible production of alkaline phosphatase in response to phosphate limitation as it is directly involved in the regulation of phoA transcription in response to pho

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=41.5929203539823, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=43.4389140271493, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=42.3423423423423, Blast_Score=163, Evalue=8e-42,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=40.6113537117904, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=40.4444444444444, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=40.5405405405405, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=38.4955752212389, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=37.8854625550661, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=38.5281385281385, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=39.5555555555556, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=39.647577092511, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=33.6322869955157, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=35.5555555555556, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=32.618025751073, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=34.9056603773585, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787487, Length=100, Percent_Identity=33, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26978; Mature: 26847

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTILLVEDEALLADTLRYNLEREGYTVLSASDGVTGLDLARAEQPDLLILDVMLPKLDG
CCEEEEEECCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHCCCCCCEEEEEEECCCCCC
FSVCRILRRETNIPIMMLTARQDEVDRIAGLELGADDYVIKPFSLGELLARVRAILRRTD
HHHHHHHHHCCCCCEEEEECCCCHHHHHHCCEECCCCEEECCCCHHHHHHHHHHHHHHCC
RQPTGVERELLTAANLKVDTGSRRVFRDNNEITLAQKEFDLLVCLMRNRGMALSRDLLLE
CCCCCCHHHHHHHCCEEEECCCCEEEECCCEEEEEHHHHHHHHEEHHCCCCCHHHHHHHH
RVWGYDFPGDSRTVDVHVRWLREKVEVDPSNPIYIQTVRGIGYRFNDQLSRSERKN
HHHCCCCCCCCEEEEEEEEEHHHHHCCCCCCCEEEEEECCCCEECCCHHHHHHCCC
>Mature Secondary Structure 
STILLVEDEALLADTLRYNLEREGYTVLSASDGVTGLDLARAEQPDLLILDVMLPKLDG
CEEEEEECCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHCCCCCCEEEEEEECCCCCC
FSVCRILRRETNIPIMMLTARQDEVDRIAGLELGADDYVIKPFSLGELLARVRAILRRTD
HHHHHHHHHCCCCCEEEEECCCCHHHHHHCCEECCCCEEECCCCHHHHHHHHHHHHHHCC
RQPTGVERELLTAANLKVDTGSRRVFRDNNEITLAQKEFDLLVCLMRNRGMALSRDLLLE
CCCCCCHHHHHHHCCEEEECCCCEEEECCCEEEEEHHHHHHHHEEHHCCCCCHHHHHHHH
RVWGYDFPGDSRTVDVHVRWLREKVEVDPSNPIYIQTVRGIGYRFNDQLSRSERKN
HHHCCCCCCCCEEEEEEEEEHHHHHCCCCCCCEEEEEECCCCEECCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8497200; 8157591 [H]