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The map label for this gene is yciL [C]

Identifier: 159897316

GI number: 159897316

Start: 886965

End: 889151

Strand: Reverse

Name: yciL [C]

Synonym: Haur_0787

Alternate gene names: 159897316

Gene position: 889151-886965 (Counterclockwise)

Preceding gene: 159897317

Following gene: 159897315

Centisome position: 14.01

GC content: 59.4

Gene sequence:

>2187_bases
ATGGAACGTTTACATAAGTTTTTGGCGCGGGCCGGCGTAGATTCACGTCGGGCTTGCGAAGAGTTGATGTTGGCTGGGCG
CGTATCGGTTAATGGACGAGTTCAACGCGAATTAGGAACCCAGATCGACCCCGATAAAGATGACATTCGAGTTGATGGCG
AACAAATTACACCTCCAACCGAGCTTCATTACGTCTTATTGCACAAACCAAGCAGCGTCATGACCACGTTGCATGACCCT
GAAGGCCGCCAAACCGTCGCCGATTTAGTCAAATCGCACAATCGTTTATTTCCCGTAGGCCGCCTCGATTACGATAGCGA
AGGGCTATTGTTGCTGACCGATGATGGTGATCTCACGTTCCGTTTGACCCACCCATCGTTCGAAGTCGAAAAAGAATATC
AGGCCTTGTTAAACCAAACACCATCAGTTGAGCAATTGCGCGAGTGGCGCAATGGGGTTGAGCTTGACGATGGCAAAACA
GCACCTGCATGGATCGAATTGTTAAATGAAACCGCCGATGGAACTTGGGTTCGGGTGGTTATTCACGAAGGTCGCAACCG
CCAAATTCGGCGGGTTGCCGAAGCATTAGGCTTAGAAGTCCGCCGCTTGATCCGGTTGCGCGAAGGCCCACTAACTTTAG
GTGAATTACAAGCAGGCCAATGGCGAGCATTAACACCCACCGAAATTGATCGTTTGCGTATGCACGGCAAGCAAAGCAAA
GCATGGACACCAGTACGCCCACAAGAAAACGCCGAGGGTGGCAAACCACGCCGTCAAGTTCGGCGGATTGATCGGTCTGG
ACAGTTGGTAGAACGTCGGGCTGATGTTGAACCGCGCTTACAACGAGCGCCTCACTTTACTTCACAGGAAAATACAATGT
CATTTGAAGATTTCTCAATCGAAGAAGAACGCTCCACCGATCGCCCACGCCGTCGCCCAGAACCTCGCCGCGAAGGTGGA
TTTAGCGACCGTGGCCCCCGCCGTGATGGCGGCAGCCCTAGCGACGACCGTGGCCCCCGCCGCGAAGGTGGATTTAGCGA
ACGCGGTCCGCGCCGTGAAGCTGGCGATTTTGGCGACCGTGGTCCACGCCGCGAAGCTGGTTTCGGCGAACGTGGTCCAC
GCCGCGATGGCGGTGGCTTTGGTGAACGCGGCCCGCGCCGCGATGGTGACGGCCCGCGCCGCGATTTTGGCGACCGTGGC
CCACGTCGTGAAGGTGGCGATTTTGGTGACCGTGGCCCACGTCGTGAAGGTGGTGGTTTCGGCGAACGCGGTCCGCGCCG
CGATGGTGACGGCCCGCGCCGCGATTTTGGTGACCGTAGTCCTCGTCGCGATGGCGATTTTGGTGACCGTGGCTCACGTC
GTGAAGGTGGCGATTTTGGTGACCGTGGTCCACGCCGTGAAGGTGGCTTTGGCGAACGCGGCCCGCGCCGTGAAGGCGAC
GGCCCACGCCGCGATTTCGGTGACCGTGGCCCACGCCGTGAAGGTGGCGGTTTTGGCGAACGTGGTCCACGCCGTGAAGG
TGGCGGTTTTGGCGAACGCGGCCCACGCCGTGAAGGTGGCGGTTTTGGCGAACGCAGTCCGCGCCGCGATGGTGGCGGCT
TTGGCGAACGCAGTCCGCGCCGTGAAGGTGGCGGCTTTGGCGAACGCGGCCCGCGCCGTGAAGGTGGCGGTTTTGGTGAC
CGTGGTCCGCGCCGTGAAGGCGGCGGTTTCGGCGAACGTGGCCCACGCCGTGAAGGTGGCGGTTTCGGCGAACGTGGCCC
ACGTCGCGATGCAAGTGGCTTCGATCGTACCAATCGTCGCGAAGAATTTTTTGATGATCGACCACGTGGCGAACGTGGCT
TGGCGCTTGATCGCGCCCATCGTGGCGATGATCGCCCTAAAAACACCTTTGGCGGTCGCCGCCCAAGCAACCAAGGCTCG
TTTGATCGCCGTGGTTTTGACAACCGTGGTCGCGACGACCGTCGTGGTTTCGATAACCGTGGCCGCGATGACCGTCGTGG
TTTCGATGATCGCGCATCAGCTCCACGCGACAAAATGGTTGAACGCGGGCCAATTTCAGCCCGCAATACGCCAGCGCCAA
CGCCAGCACCTACGCCGGCCCCAGTTGCCGAGCAAGCAGCTCAGCCAGCCCGTCGGATGCGCGTGGTACGGCGTTTGAAA
AAGGCAGGCGGTGATGAACAAGCTTAA

Upstream 100 bases:

>100_bases
GCTTGATGCACGTATTATCGTTCGGATGTCCGCTGTACTCCCGATCATTCAAGCATGCACTGACGACCCCAACAGTAGAA
CCACGACCTGTGGAGTAATA

Downstream 100 bases:

>100_bases
ACAGGCCTATCTCCAATTAGCAGTTGAACGTGATCGCACACGTCGTCAAGCCGAACGCTACGCCCATGAATCGCAGCGTT
GGACAGAACGGCTTGCCCTA

Product: pseudouridine synthase

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 728; Mature: 728

Protein sequence:

>728_residues
MERLHKFLARAGVDSRRACEELMLAGRVSVNGRVQRELGTQIDPDKDDIRVDGEQITPPTELHYVLLHKPSSVMTTLHDP
EGRQTVADLVKSHNRLFPVGRLDYDSEGLLLLTDDGDLTFRLTHPSFEVEKEYQALLNQTPSVEQLREWRNGVELDDGKT
APAWIELLNETADGTWVRVVIHEGRNRQIRRVAEALGLEVRRLIRLREGPLTLGELQAGQWRALTPTEIDRLRMHGKQSK
AWTPVRPQENAEGGKPRRQVRRIDRSGQLVERRADVEPRLQRAPHFTSQENTMSFEDFSIEEERSTDRPRRRPEPRREGG
FSDRGPRRDGGSPSDDRGPRREGGFSERGPRREAGDFGDRGPRREAGFGERGPRRDGGGFGERGPRRDGDGPRRDFGDRG
PRREGGDFGDRGPRREGGGFGERGPRRDGDGPRRDFGDRSPRRDGDFGDRGSRREGGDFGDRGPRREGGFGERGPRREGD
GPRRDFGDRGPRREGGGFGERGPRREGGGFGERGPRREGGGFGERSPRRDGGGFGERSPRREGGGFGERGPRREGGGFGD
RGPRREGGGFGERGPRREGGGFGERGPRRDASGFDRTNRREEFFDDRPRGERGLALDRAHRGDDRPKNTFGGRRPSNQGS
FDRRGFDNRGRDDRRGFDNRGRDDRRGFDDRASAPRDKMVERGPISARNTPAPTPAPTPAPVAEQAAQPARRMRVVRRLK
KAGGDEQA

Sequences:

>Translated_728_residues
MERLHKFLARAGVDSRRACEELMLAGRVSVNGRVQRELGTQIDPDKDDIRVDGEQITPPTELHYVLLHKPSSVMTTLHDP
EGRQTVADLVKSHNRLFPVGRLDYDSEGLLLLTDDGDLTFRLTHPSFEVEKEYQALLNQTPSVEQLREWRNGVELDDGKT
APAWIELLNETADGTWVRVVIHEGRNRQIRRVAEALGLEVRRLIRLREGPLTLGELQAGQWRALTPTEIDRLRMHGKQSK
AWTPVRPQENAEGGKPRRQVRRIDRSGQLVERRADVEPRLQRAPHFTSQENTMSFEDFSIEEERSTDRPRRRPEPRREGG
FSDRGPRRDGGSPSDDRGPRREGGFSERGPRREAGDFGDRGPRREAGFGERGPRRDGGGFGERGPRRDGDGPRRDFGDRG
PRREGGDFGDRGPRREGGGFGERGPRRDGDGPRRDFGDRSPRRDGDFGDRGSRREGGDFGDRGPRREGGFGERGPRREGD
GPRRDFGDRGPRREGGGFGERGPRREGGGFGERGPRREGGGFGERSPRRDGGGFGERSPRREGGGFGERGPRREGGGFGD
RGPRREGGGFGERGPRREGGGFGERGPRRDASGFDRTNRREEFFDDRPRGERGLALDRAHRGDDRPKNTFGGRRPSNQGS
FDRRGFDNRGRDDRRGFDNRGRDDRRGFDDRASAPRDKMVERGPISARNTPAPTPAPTPAPVAEQAAQPARRMRVVRRLK
KAGGDEQA
>Mature_728_residues
MERLHKFLARAGVDSRRACEELMLAGRVSVNGRVQRELGTQIDPDKDDIRVDGEQITPPTELHYVLLHKPSSVMTTLHDP
EGRQTVADLVKSHNRLFPVGRLDYDSEGLLLLTDDGDLTFRLTHPSFEVEKEYQALLNQTPSVEQLREWRNGVELDDGKT
APAWIELLNETADGTWVRVVIHEGRNRQIRRVAEALGLEVRRLIRLREGPLTLGELQAGQWRALTPTEIDRLRMHGKQSK
AWTPVRPQENAEGGKPRRQVRRIDRSGQLVERRADVEPRLQRAPHFTSQENTMSFEDFSIEEERSTDRPRRRPEPRREGG
FSDRGPRRDGGSPSDDRGPRREGGFSERGPRREAGDFGDRGPRREAGFGERGPRRDGGGFGERGPRRDGDGPRRDFGDRG
PRREGGDFGDRGPRREGGGFGERGPRRDGDGPRRDFGDRSPRRDGDFGDRGSRREGGDFGDRGPRREGGFGERGPRREGD
GPRRDFGDRGPRREGGGFGERGPRREGGGFGERGPRREGGGFGERSPRRDGGGFGERSPRREGGGFGERGPRREGGGFGD
RGPRREGGGFGERGPRREGGGFGERGPRRDASGFDRTNRREEFFDDRPRGERGLALDRAHRGDDRPKNTFGGRRPSNQGS
FDRRGFDNRGRDDRRGFDNRGRDDRRGFDDRASAPRDKMVERGPISARNTPAPTPAPTPAPVAEQAAQPARRMRVVRRLK
KAGGDEQA

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=240, Percent_Identity=40.8333333333333, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1790453, Length=241, Percent_Identity=33.195020746888, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI87081838, Length=176, Percent_Identity=36.9318181818182, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788510, Length=234, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 81710; Mature: 81710

Theoretical pI: Translated: 11.40; Mature: 11.40

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLHKFLARAGVDSRRACEELMLAGRVSVNGRVQRELGTQIDPDKDDIRVDGEQITPPT
CHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCEEECCCCCCCCC
ELHYVLLHKPSSVMTTLHDPEGRQTVADLVKSHNRLFPVGRLDYDSEGLLLLTDDGDLTF
CEEEEEEECCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEE
RLTHPSFEVEKEYQALLNQTPSVEQLREWRNGVELDDGKTAPAWIELLNETADGTWVRVV
EEECCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEE
IHEGRNRQIRRVAEALGLEVRRLIRLREGPLTLGELQAGQWRALTPTEIDRLRMHGKQSK
EECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCCCC
AWTPVRPQENAEGGKPRRQVRRIDRSGQLVERRADVEPRLQRAPHFTSQENTMSFEDFSI
CCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCC
EEERSTDRPRRRPEPRREGGFSDRGPRRDGGSPSDDRGPRREGGFSERGPRREAGDFGDR
CHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GPRREAGFGERGPRRDGGGFGERGPRRDGDGPRRDFGDRGPRREGGDFGDRGPRREGGGF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCC
GERGPRRDGDGPRRDFGDRSPRRDGDFGDRGSRREGGDFGDRGPRREGGFGERGPRREGD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GPRRDFGDRGPRREGGGFGERGPRREGGGFGERGPRREGGGFGERSPRRDGGGFGERSPR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
REGGGFGERGPRREGGGFGDRGPRREGGGFGERGPRREGGGFGERGPRRDASGFDRTNRR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
EEFFDDRPRGERGLALDRAHRGDDRPKNTFGGRRPSNQGSFDRRGFDNRGRDDRRGFDNR
HHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHCCCCCC
GRDDRRGFDDRASAPRDKMVERGPISARNTPAPTPAPTPAPVAEQAAQPARRMRVVRRLK
CCHHHCCCCHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KAGGDEQA
HCCCCCCC
>Mature Secondary Structure
MERLHKFLARAGVDSRRACEELMLAGRVSVNGRVQRELGTQIDPDKDDIRVDGEQITPPT
CHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCEEECCCCCCCCC
ELHYVLLHKPSSVMTTLHDPEGRQTVADLVKSHNRLFPVGRLDYDSEGLLLLTDDGDLTF
CEEEEEEECCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEE
RLTHPSFEVEKEYQALLNQTPSVEQLREWRNGVELDDGKTAPAWIELLNETADGTWVRVV
EEECCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEE
IHEGRNRQIRRVAEALGLEVRRLIRLREGPLTLGELQAGQWRALTPTEIDRLRMHGKQSK
EECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCCCC
AWTPVRPQENAEGGKPRRQVRRIDRSGQLVERRADVEPRLQRAPHFTSQENTMSFEDFSI
CCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCC
EEERSTDRPRRRPEPRREGGFSDRGPRRDGGSPSDDRGPRREGGFSERGPRREAGDFGDR
CHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GPRREAGFGERGPRRDGGGFGERGPRRDGDGPRRDFGDRGPRREGGDFGDRGPRREGGGF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCC
GERGPRRDGDGPRRDFGDRSPRRDGDFGDRGSRREGGDFGDRGPRREGGFGERGPRREGD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GPRRDFGDRGPRREGGGFGERGPRREGGGFGERGPRREGGGFGERSPRRDGGGFGERSPR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
REGGGFGERGPRREGGGFGDRGPRREGGGFGERGPRREGGGFGERGPRRDASGFDRTNRR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
EEFFDDRPRGERGLALDRAHRGDDRPKNTFGGRRPSNQGSFDRRGFDNRGRDDRRGFDNR
HHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHCCCCCC
GRDDRRGFDDRASAPRDKMVERGPISARNTPAPTPAPTPAPVAEQAAQPARRMRVVRRLK
CCHHHCCCCHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KAGGDEQA
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]