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The map label for this gene is frzE [H]

Identifier: 159897254

GI number: 159897254

Start: 833061

End: 835349

Strand: Direct

Name: frzE [H]

Synonym: Haur_0725

Alternate gene names: 159897254

Gene position: 833061-835349 (Clockwise)

Preceding gene: 159897253

Following gene: 159897255

Centisome position: 13.13

GC content: 54.7

Gene sequence:

>2289_bases
ATGGGCGGTTTTGATTTATCAGCATTTTTTGGCCAGTTTCGCGAAGAAACTGAAGAGAATGTGCGGGCCTTGACCACAGG
CTTATTGGCCTTGGAGTCAAACCCAGGCGATCGCGAAGCGATTGATACGATTTTTCGGGCGGCGCATACGATCAAAGGTT
CGGCGCGTATGCTGGGTCAAGTCGATATGGGGCGGTTGGCGCATACCATGGAAAGTTTGCTTTCGGCCTTGCGCAGTGGC
ATGCTAGCCATGAATTCGAGCATTAACGATGTGCTACTGGCCAGTGTTGATGTATTGCTGGTGTTGAATTCCCAAGTCAA
CGAGCCACCGCCAACCGACCCCAACGTTGATCGTTTGGTTGAGCAACTGAATGCCTTGGCTGCTGGCGAAAGCTTGCCTG
CTGCGCCGATTGTCGCGCCAGTAACCGAACCAGAACCAGAGCCTGAGCCAGTAGTGCTTGAGCAACCCAAGCCCGAACCA
GCGGTTGCTAAGCCAGCCGCGCCTGCCAAACCCAAAAAATCAGCCTCAGCCGAAGCCCCCAAGTCGGTGAGTAGCACCCG
TTCAACCGTGCGTGTGCCAATTTCGCGCTTAGATCGTTTGTTGAATACCGCTGGCGAGTTGGTCGTAACCCGCCAATTGC
ACCTTGAGCATGTCGCTGATCTTGAGGCTTTGGATAAATTGCTGACCAAAAGTGAGCGCCTGAGCCAACAATTGAGCGAA
CGCTTGACGGGTCAACGGGTGACCTTTCAGCAACGGCGCGAGGCCAGCGAATTAGCCAGCCAATTGCAAAATCTGGCCCA
ATCGACCCGCAATCAGTTGCGTTTGCTAACCGAGCGTTGGAGCAGCCATAGCGCCGCCAGTGAGGCCTTGGTCGATGAAC
TTGAGGCTGAGGTGATGGCGACCCGTTTGCAACCAGTCGCTGGTTTGTTTGCACCAATTCCTCGGGCCGTGCGCGAGCTG
GCTCGTTCGTTGGGCAAAGAAGTTAACTTAATCACCGAAGGCGAAACCACCGAGGCCGATCGCAAAGTGATTGAGTTAAT
GGCTGATCCGTTGGTGCATTTGGTGCGCAACGCGCTTGATCATGGCATCGAAAGCCCCGATGAGCGGGTGAAAGCCCACA
AGCCTGCCGAAGCAAGCTTGCGTTTAGAAGCTCGCTCGTTGGGCGGCACGATTGAAATTATTATTAGCGACGATGGCCGT
GGCATCGATCCAGCGGTGATTCGGGCAACTGCAATTAAACGCGGAATTATCGAGGCTGATACAGCGGCTCGCTTGCGTGA
TGAAGAAGCTTTGGAGTTGATCTGGCAGCCTGGTTTTTCCACCAGCGCAATCATCACCGATGTTTCAGGCCGTGGCGTTG
GCATGGACGTGGTACGGGCAGCAGTGACCGAGGTTGGTGGGCGGGTCGATGTGCATTCGGTGCTTGGCCAAGGCACGACC
TTCACGCTGATTTTGCCAATTACCTTGCTAACCACCCGCGTGTTGTTGTTTGATGTGGCTGGCACAACCTATGCCTTGCC
TTCGACTGCTTGTCTAGGTGGGCGGCGGGTTGCTGGCGGGCAAATTCAGACCGTCGAAGGGCGACCAACCGTGCGGGTTG
ATGAGCGCAGCGTGAGCATTGTAGCGCTTGCGCCCTTGCTTGAGCAGCGTGGCCCCTTGCCGCAACCATCGGATATTTCC
AATTTGGTGATTTTGGGGCCAGCTAATCGCCCATTGGCCTTGTTGGTCGATAAATTGGTCGATGAACGTGAGGTGGTGGT
TAAATCGTTGGGCGCATTGTTGCATGAACAACGTTTGTGTACTGGCGCGATTGCCCTGCCTGATGGGCGTTTGGTGTTAG
TGCTCAATCCCTTGGCGATTGCGGCGCGGGCACGTGAATGGGGCAAACCAGTTGCCTTGCCAGCGCCAACCAAGCTCCAG
CCTGCCAAATTATTGGTCGCGGAAGATTCATTTACCACCCGCGAACTGCTCCGATCCATGCTGCAATCGGCGGGCTATGT
GGTTGAAACGGCGATTAACGGCCAAGATGCGCTTGACAAGCTCAATCACAATTCCTACGATCTGCTGGTAAGCGATGTTG
AAATGCCGTTGCTAACTGGCTTTGAGCTAACCCGCCGTGTGCGTGCCCATGACCGTTTGCGCCAACTGCCAATTATCATT
ATCACCAGCTTGGCCCGCGATAGCGATCGGCGTGAAGGCTTGTTGGCTGGTGCGCAAGCCTATATCGTCAAAAGCCAGTT
TGATCAAAGCAACTTGCTCGAAACGATTCATCAATTACTTGGCCGCTAA

Upstream 100 bases:

>100_bases
CCAAACTGCCGATGCCGCATCCAAACTCACCGCGATTGCAAATCGCTTGCATTCGTTGGTCAACATCGAGGCACATACAC
GCTAAGCGAGGAGCTATCGC

Downstream 100 bases:

>100_bases
AATAGCGCAGCCCTGAAGGCCTATATTCCCCTGCGAGGAGTTTTTCAATGAGTGAACGCATCTTAGTTGTTGACGATAGC
AAACTGGTTACCGATATTGT

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 762; Mature: 761

Protein sequence:

>762_residues
MGGFDLSAFFGQFREETEENVRALTTGLLALESNPGDREAIDTIFRAAHTIKGSARMLGQVDMGRLAHTMESLLSALRSG
MLAMNSSINDVLLASVDVLLVLNSQVNEPPPTDPNVDRLVEQLNALAAGESLPAAPIVAPVTEPEPEPEPVVLEQPKPEP
AVAKPAAPAKPKKSASAEAPKSVSSTRSTVRVPISRLDRLLNTAGELVVTRQLHLEHVADLEALDKLLTKSERLSQQLSE
RLTGQRVTFQQRREASELASQLQNLAQSTRNQLRLLTERWSSHSAASEALVDELEAEVMATRLQPVAGLFAPIPRAVREL
ARSLGKEVNLITEGETTEADRKVIELMADPLVHLVRNALDHGIESPDERVKAHKPAEASLRLEARSLGGTIEIIISDDGR
GIDPAVIRATAIKRGIIEADTAARLRDEEALELIWQPGFSTSAIITDVSGRGVGMDVVRAAVTEVGGRVDVHSVLGQGTT
FTLILPITLLTTRVLLFDVAGTTYALPSTACLGGRRVAGGQIQTVEGRPTVRVDERSVSIVALAPLLEQRGPLPQPSDIS
NLVILGPANRPLALLVDKLVDEREVVVKSLGALLHEQRLCTGAIALPDGRLVLVLNPLAIAARAREWGKPVALPAPTKLQ
PAKLLVAEDSFTTRELLRSMLQSAGYVVETAINGQDALDKLNHNSYDLLVSDVEMPLLTGFELTRRVRAHDRLRQLPIII
ITSLARDSDRREGLLAGAQAYIVKSQFDQSNLLETIHQLLGR

Sequences:

>Translated_762_residues
MGGFDLSAFFGQFREETEENVRALTTGLLALESNPGDREAIDTIFRAAHTIKGSARMLGQVDMGRLAHTMESLLSALRSG
MLAMNSSINDVLLASVDVLLVLNSQVNEPPPTDPNVDRLVEQLNALAAGESLPAAPIVAPVTEPEPEPEPVVLEQPKPEP
AVAKPAAPAKPKKSASAEAPKSVSSTRSTVRVPISRLDRLLNTAGELVVTRQLHLEHVADLEALDKLLTKSERLSQQLSE
RLTGQRVTFQQRREASELASQLQNLAQSTRNQLRLLTERWSSHSAASEALVDELEAEVMATRLQPVAGLFAPIPRAVREL
ARSLGKEVNLITEGETTEADRKVIELMADPLVHLVRNALDHGIESPDERVKAHKPAEASLRLEARSLGGTIEIIISDDGR
GIDPAVIRATAIKRGIIEADTAARLRDEEALELIWQPGFSTSAIITDVSGRGVGMDVVRAAVTEVGGRVDVHSVLGQGTT
FTLILPITLLTTRVLLFDVAGTTYALPSTACLGGRRVAGGQIQTVEGRPTVRVDERSVSIVALAPLLEQRGPLPQPSDIS
NLVILGPANRPLALLVDKLVDEREVVVKSLGALLHEQRLCTGAIALPDGRLVLVLNPLAIAARAREWGKPVALPAPTKLQ
PAKLLVAEDSFTTRELLRSMLQSAGYVVETAINGQDALDKLNHNSYDLLVSDVEMPLLTGFELTRRVRAHDRLRQLPIII
ITSLARDSDRREGLLAGAQAYIVKSQFDQSNLLETIHQLLGR
>Mature_761_residues
GGFDLSAFFGQFREETEENVRALTTGLLALESNPGDREAIDTIFRAAHTIKGSARMLGQVDMGRLAHTMESLLSALRSGM
LAMNSSINDVLLASVDVLLVLNSQVNEPPPTDPNVDRLVEQLNALAAGESLPAAPIVAPVTEPEPEPEPVVLEQPKPEPA
VAKPAAPAKPKKSASAEAPKSVSSTRSTVRVPISRLDRLLNTAGELVVTRQLHLEHVADLEALDKLLTKSERLSQQLSER
LTGQRVTFQQRREASELASQLQNLAQSTRNQLRLLTERWSSHSAASEALVDELEAEVMATRLQPVAGLFAPIPRAVRELA
RSLGKEVNLITEGETTEADRKVIELMADPLVHLVRNALDHGIESPDERVKAHKPAEASLRLEARSLGGTIEIIISDDGRG
IDPAVIRATAIKRGIIEADTAARLRDEEALELIWQPGFSTSAIITDVSGRGVGMDVVRAAVTEVGGRVDVHSVLGQGTTF
TLILPITLLTTRVLLFDVAGTTYALPSTACLGGRRVAGGQIQTVEGRPTVRVDERSVSIVALAPLLEQRGPLPQPSDISN
LVILGPANRPLALLVDKLVDEREVVVKSLGALLHEQRLCTGAIALPDGRLVLVLNPLAIAARAREWGKPVALPAPTKLQP
AKLLVAEDSFTTRELLRSMLQSAGYVVETAINGQDALDKLNHNSYDLLVSDVEMPLLTGFELTRRVRAHDRLRQLPIIII
TSLARDSDRREGLLAGAQAYIVKSQFDQSNLLETIHQLLGR

Specific function: FrzE is involved in a sensory transduction pathway that controls the frequency at which cells reverse their gliding direction. FrzE seems to be capable of autophosphorylating itself on an histidine residue and then to transfer that group to an aspartate r

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=469, Percent_Identity=32.1961620469083, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI1788713, Length=116, Percent_Identity=37.9310344827586, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=34.453781512605, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786784, Length=120, Percent_Identity=35, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR005467
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF02518 HATPase_c; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82367; Mature: 82235

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGFDLSAFFGQFREETEENVRALTTGLLALESNPGDREAIDTIFRAAHTIKGSARMLGQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCHHHHHHH
VDMGRLAHTMESLLSALRSGMLAMNSSINDVLLASVDVLLVLNSQVNEPPPTDPNVDRLV
HHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHH
EQLNALAAGESLPAAPIVAPVTEPEPEPEPVVLEQPKPEPAVAKPAAPAKPKKSASAEAP
HHHHHHHCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
KSVSSTRSTVRVPISRLDRLLNTAGELVVTRQLHLEHVADLEALDKLLTKSERLSQQLSE
CHHHHHHHHEECCHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLTGQRVTFQQRREASELASQLQNLAQSTRNQLRLLTERWSSHSAASEALVDELEAEVMA
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TRLQPVAGLFAPIPRAVRELARSLGKEVNLITEGETTEADRKVIELMADPLVHLVRNALD
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
HGIESPDERVKAHKPAEASLRLEARSLGGTIEIIISDDGRGIDPAVIRATAIKRGIIEAD
CCCCCCHHHHHCCCCCCHHEEEEHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCC
TAARLRDEEALELIWQPGFSTSAIITDVSGRGVGMDVVRAAVTEVGGRVDVHSVLGQGTT
HHHHHCCHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEHHHHHCCCCE
FTLILPITLLTTRVLLFDVAGTTYALPSTACLGGRRVAGGQIQTVEGRPTVRVDERSVSI
EEEHHHHHHHHHHHHHHHCCCCCEECCCHHHCCCCEECCCEEEEECCCCCEEECCCCEEE
VALAPLLEQRGPLPQPSDISNLVILGPANRPLALLVDKLVDEREVVVKSLGALLHEQRLC
HHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGAIALPDGRLVLVLNPLAIAARAREWGKPVALPAPTKLQPAKLLVAEDSFTTRELLRSM
HCEEECCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHH
LQSAGYVVETAINGQDALDKLNHNSYDLLVSDVEMPLLTGFELTRRVRAHDRLRQLPIII
HHHCCEEEEEECCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHE
ITSLARDSDRREGLLAGAQAYIVKSQFDQSNLLETIHQLLGR
EEHHHCCCCHHHHHHHCHHHHEEHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
GGFDLSAFFGQFREETEENVRALTTGLLALESNPGDREAIDTIFRAAHTIKGSARMLGQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCHHHHHHH
VDMGRLAHTMESLLSALRSGMLAMNSSINDVLLASVDVLLVLNSQVNEPPPTDPNVDRLV
HHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHH
EQLNALAAGESLPAAPIVAPVTEPEPEPEPVVLEQPKPEPAVAKPAAPAKPKKSASAEAP
HHHHHHHCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
KSVSSTRSTVRVPISRLDRLLNTAGELVVTRQLHLEHVADLEALDKLLTKSERLSQQLSE
CHHHHHHHHEECCHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLTGQRVTFQQRREASELASQLQNLAQSTRNQLRLLTERWSSHSAASEALVDELEAEVMA
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TRLQPVAGLFAPIPRAVRELARSLGKEVNLITEGETTEADRKVIELMADPLVHLVRNALD
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
HGIESPDERVKAHKPAEASLRLEARSLGGTIEIIISDDGRGIDPAVIRATAIKRGIIEAD
CCCCCCHHHHHCCCCCCHHEEEEHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCC
TAARLRDEEALELIWQPGFSTSAIITDVSGRGVGMDVVRAAVTEVGGRVDVHSVLGQGTT
HHHHHCCHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEHHHHHCCCCE
FTLILPITLLTTRVLLFDVAGTTYALPSTACLGGRRVAGGQIQTVEGRPTVRVDERSVSI
EEEHHHHHHHHHHHHHHHCCCCCEECCCHHHCCCCEECCCEEEEECCCCCEEECCCCEEE
VALAPLLEQRGPLPQPSDISNLVILGPANRPLALLVDKLVDEREVVVKSLGALLHEQRLC
HHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGAIALPDGRLVLVLNPLAIAARAREWGKPVALPAPTKLQPAKLLVAEDSFTTRELLRSM
HCEEECCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHH
LQSAGYVVETAINGQDALDKLNHNSYDLLVSDVEMPLLTGFELTRRVRAHDRLRQLPIII
HHHCCEEEEEECCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHE
ITSLARDSDRREGLLAGAQAYIVKSQFDQSNLLETIHQLLGR
EEHHHCCCCHHHHHHHCHHHHEEHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2165608; 2123853 [H]