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The map label for this gene is pabA [H]

Identifier: 159897126

GI number: 159897126

Start: 689327

End: 689926

Strand: Direct

Name: pabA [H]

Synonym: Haur_0597

Alternate gene names: 159897126

Gene position: 689327-689926 (Clockwise)

Preceding gene: 159897125

Following gene: 159897127

Centisome position: 10.86

GC content: 50.67

Gene sequence:

>600_bases
ATGGCCGTCTTGCTACTCGATAACTACGATTCCTTTACCTATAATTTGTATCAATATTTCTGCGAACTTGGCGCAGAGGT
GGTGGTCAAGCGCAACGATGAAATTGAAGTCGATGATATTCGCCACATGGAAGCCATTGACCGGATTGTAATTTCGCCTG
GACCATGTACGCCTGCCGAAGCCGGCATTAGCGTGCCGCTGATTCGCGAATTGTGTATGGAATACCCAATTTTAGGCGTT
TGTCTGGGACATCAATCGATTGGGGCCGCCTTTGGCGGGCGAGTGATTCGCGCTCCCCAATTGCGCCACGGCAAAACCTC
ACCGATCACTCACTTGAATGTTGGGATTTTCGCTGGTGTGCCTTCACCCTTCACCGCCACCCGCTATCACTCATTGATTG
TCGAGGAATCCAGCTTGCCTAGTGATCTTGAGGCTACCGCTTGGAGTGATGATGGCTTGATTATGGGTTTGCGCCACCGC
ACCTTGCCAATCGAAGGCGTGCAATTCCACCCCGAATCGATTATGACTGAGCATGGCAAAGTGTTACTTGCTAACTTCTT
GAGCATTGCTAAACCAGAGTTGGCCGAGGTTAGGGGTTAG

Upstream 100 bases:

>100_bases
GCTCGAAGATGTTAGCGCTGAGATCTTGTTTAATAGTCCAATTCCTGTTTTACTTGTCCAAAATACCAGCGATTTCTAAA
CCGCAATCAAGGAGTTTGCT

Downstream 100 bases:

>100_bases
GGGTTAGGGATCAGGGGTCAGAGGTCAGGAATGGATTCCGTGAATCTGTGGCTAAAAACAGCTTTGCGTTTTTTGCGTCC
TTCGCGGTTCCGTGCTTCGT

Product: glutamine amidotransferase of anthranilate synthase

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MAVLLLDNYDSFTYNLYQYFCELGAEVVVKRNDEIEVDDIRHMEAIDRIVISPGPCTPAEAGISVPLIRELCMEYPILGV
CLGHQSIGAAFGGRVIRAPQLRHGKTSPITHLNVGIFAGVPSPFTATRYHSLIVEESSLPSDLEATAWSDDGLIMGLRHR
TLPIEGVQFHPESIMTEHGKVLLANFLSIAKPELAEVRG

Sequences:

>Translated_199_residues
MAVLLLDNYDSFTYNLYQYFCELGAEVVVKRNDEIEVDDIRHMEAIDRIVISPGPCTPAEAGISVPLIRELCMEYPILGV
CLGHQSIGAAFGGRVIRAPQLRHGKTSPITHLNVGIFAGVPSPFTATRYHSLIVEESSLPSDLEATAWSDDGLIMGLRHR
TLPIEGVQFHPESIMTEHGKVLLANFLSIAKPELAEVRG
>Mature_198_residues
AVLLLDNYDSFTYNLYQYFCELGAEVVVKRNDEIEVDDIRHMEAIDRIVISPGPCTPAEAGISVPLIRELCMEYPILGVC
LGHQSIGAAFGGRVIRAPQLRHGKTSPITHLNVGIFAGVPSPFTATRYHSLIVEESSLPSDLEATAWSDDGLIMGLRHRT
LPIEGVQFHPESIMTEHGKVLLANFLSIAKPELAEVRG

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=165, Percent_Identity=29.6969696969697, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=62.1621621621622, Blast_Score=244, Evalue=2e-66,
Organism=Escherichia coli, GI1787517, Length=194, Percent_Identity=41.2371134020619, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1786215, Length=142, Percent_Identity=27.4647887323944, Blast_Score=62, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=189, Percent_Identity=50.2645502645503, Blast_Score=195, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6324361, Length=214, Percent_Identity=33.1775700934579, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 21865; Mature: 21734

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLLLDNYDSFTYNLYQYFCELGAEVVVKRNDEIEVDDIRHMEAIDRIVISPGPCTPAE
CEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHEEECCCCCCCCC
AGISVPLIRELCMEYPILGVCLGHQSIGAAFGGRVIRAPQLRHGKTSPITHLNVGIFAGV
CCCCCHHHHHHHHHCCEEEEEECCHHHHHHHCCCEEECCCCCCCCCCCEEEEEEEEEECC
PSPFTATRYHSLIVEESSLPSDLEATAWSDDGLIMGLRHRTLPIEGVQFHPESIMTEHGK
CCCCCHHHHHEEEEECCCCCCCCCCEEECCCCEEEEEECCCCCCCCCEECCHHHHHHCCH
VLLANFLSIAKPELAEVRG
HHHHHHHHHCCCHHHHCCC
>Mature Secondary Structure 
AVLLLDNYDSFTYNLYQYFCELGAEVVVKRNDEIEVDDIRHMEAIDRIVISPGPCTPAE
EEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHEEECCCCCCCCC
AGISVPLIRELCMEYPILGVCLGHQSIGAAFGGRVIRAPQLRHGKTSPITHLNVGIFAGV
CCCCCHHHHHHHHHCCEEEEEECCHHHHHHHCCCEEECCCCCCCCCCCEEEEEEEEEECC
PSPFTATRYHSLIVEESSLPSDLEATAWSDDGLIMGLRHRTLPIEGVQFHPESIMTEHGK
CCCCCHHHHHEEEEECCCCCCCCCCEEECCCCEEEEEECCCCCCCCCEECCHHHHHHCCH
VLLANFLSIAKPELAEVRG
HHHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3894673 [H]