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The map label for this gene is clpB [H]

Identifier: 159897035

GI number: 159897035

Start: 585112

End: 587625

Strand: Direct

Name: clpB [H]

Synonym: Haur_0503

Alternate gene names: 159897035

Gene position: 585112-587625 (Clockwise)

Preceding gene: 159897034

Following gene: 159897037

Centisome position: 9.22

GC content: 51.27

Gene sequence:

>2514_bases
ATGGGTGCATACGACAAAATGAGCCGCCGCGCTAAGCAAGTGATGAGCTTTGCCCAAGAAGAGGCGCGAGCGTTTAATCA
TCCTTACATCGGCACCGAGCATTTATTGCTGGGCTTGATTTTGGAAGGTGAAGGGGTCGCCGCTCGTGTGTTGGCTGAAC
TTGGTGTGACCATCACAAAAGCCCGCAATGCTGTTGAATTTATTGTTGGCCACGGCGATGGTCCACGCTCGACTGCCGAG
ATTGATTTAACCGCCCGCGCCAAAAAAGTTTTTGAGTATGCAATCGATGAAGCTCGCAAACTCAACCATACCTATATCAG
CACCGAACATATTTTGCTGGGTTTGGTGCGCAATGCCGAAGGTGTTGCAACGGGTGTGCTCGAAATTATGAATGTTGGGC
TGGATCAGGTTCGCACCCAAGTGATGCGCATGATGCGTCAAGGGGTTGGCGGCAGCAGCACGCCTAGCCCAAGCGCTGGG
GGCGAACGCCAAGCCAAACAAAGCAAAACGCCCTATCTCGATGCGCTTTCAACCGATTTGACCGAGTTGGCCGAAGCTGG
CCGACTTGATCCAGTGGTTGGTCGCAAAGATGAAATTGAGCGCGTGATTCAGATTTTGTCACGCCGCACCAAAAATAATC
CGGCCCTGATTGGCGAGCCTGGGGTTGGTAAAACTGCGATCGCTGAGGGTTTGGCGCAACGAATTGTCGCTGATGATGTT
CCAGATTCACTCAAAGGCAAGCGTTTGGTAACGCTTGATATGGGGGCTTTGGTGGCTGGAACCAAATATCGCGGCCAATT
CGAGGAACGCCTCAAACGGGTCGTTGACGAAATTAAAGAAAGCCGTTGTATTTTATTTATCGATGAATTCCACACGATTA
TTGGCGCTGGTGGAGCCGAAGGCACACTCGATGCCGCCAATATTTTGAAACCAGCCCTTTCACGCGGCGAATTGCAATGT
ATTGGCGCAACGACGCTTGATGAGTTCCGCAAATATATCGAAAAAGATGCAGCACTCGAACGGCGTTTTCAACCAGTGAT
GGTCGATGAACCAACCATTGAAGAAACGATCGAGATTTTGCGCGGCATCAAAACTCGCTACGAAGATTTCCATCAATTGC
AAATTGAGGACGAAGCGATTACTGCCGCTGCCGTGCTAAGTGCTCGCTATGTGCCCGATCGTTTCTTGCCTGATAAAGCG
ATTGACTTGATCGACGAAGCCTCCTCGCGGGTGCGCATGTATCGCTCAGCCACGCCATCGGCCTTACGCGATGCCTTGCG
TGGGCTTGATGCGATTCGCAAAGAAAAAGATGCAGCCTTGGAAGAAGGCCAATTCGAAGTCGTGCAAGATCTACGGGTTC
GCGAAGAGCGTATGCTCCAGCGCATCACCGATCTTGAAGACGAAGAAGAAAAGACCCGTGGCTCGGAGCAACGCAAAGGC
AAGCCGTATGTAACCCAAGAAGATATTGCCGAAGTTGTGGCAATGTGGACAGGGATTCCCGTCATGCGCTTGGCCAGCGA
AGAAACCGAACGACTCATGAAGATGGAAGACTATTTGCATGAGCGGGTAATCGGCCAAGAGGAACCAATTTCGACGATTG
CTCGGGCTGTGCGGCGTGCCCGCGCTGGCCTGAAAGATCCTAAGCGCCCAATTGGCTCGTTCATTTTCTTGGGCCCAACT
GGGGTTGGTAAAACCTTGCTGGCCAAGGCCTTGGCTGAGTTTATGTTTGGCTCAGAAGATGCCTTGATCAAAATCGATAT
GTCGGAGTTCCAAGAGCGTTTCAATACCTCGCGCTTGGTTGGCTCGCCTCCAGGTTATGTTGGCTATGGTGAGGGCGGTC
AATTGACTGACGCTGTACGCCGTCGCCCCTATAGCGTGGTGCTGTTCGACGAAATCGAAAAAGCTCACCCCGATACCTTC
AACTTGTTGTTGCAAGTGTTGGAAGATGGCAACTTGACCGATGGCAAGGGCCGACGCGTCGATTTCCGCAATACCGTGAT
TATCATGACTTCGAATGTTGGCACCGAACAAATTCGGCGTGGTTCGCGGATTGGCTTCGGTGGCAATCGCAACACGATCG
ATGTTGAGGATACCCGCAAGAAGGTTGATGATGAACTGAAGCGCATGTTCCGACCAGAGTTTCTCAACCGGATCGATGGA
ACAATCATTTTCCATCCATTGACCGATATCGAGATTCGCAACATTGCCCGCTTGGAAGTCAATCGCGTGCGCAAGCAATT
GGTCGATCATCAAATTGATCTGTTGGTAACTGATGAAACCCTTGATCTGTTGGCCAAACGTGGTTACGATCCAACCTACG
GCGCTCGTCCATTGCGCCGCGTCATCACCAATATGATCGAAGATGGCTTGGCTGAAGGCTTGCTACAAGGTCGCTTCAAA
GACGGCGATAAGATTCATATCGAGCTTGAGGATAACGAAGTGGTGTTACGTTCAGAGCGTGAAGCTGCCGAGTTGGAAAA
TCCCAGTGTCGAGCCTGAAGCCGAATTAGTCTAA

Upstream 100 bases:

>100_bases
TCCGCCTATCGGCACTCAGCAGCATCGACTATTTGTCATAGATAACACGCCGAGGCCCAATCTTACTCATCCTAAGGTTG
CCTCGCTTTGGAGCAAACAT

Downstream 100 bases:

>100_bases
ACCTCAAAAAAACGCCCTGATCGCAATGATCAGGGCGTTTTTGCATTTCCTCGCCAATTGTTGTTATTGGGCGACTGCGG
TAGCAACCAAATCCAAGGTC

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 837; Mature: 836

Protein sequence:

>837_residues
MGAYDKMSRRAKQVMSFAQEEARAFNHPYIGTEHLLLGLILEGEGVAARVLAELGVTITKARNAVEFIVGHGDGPRSTAE
IDLTARAKKVFEYAIDEARKLNHTYISTEHILLGLVRNAEGVATGVLEIMNVGLDQVRTQVMRMMRQGVGGSSTPSPSAG
GERQAKQSKTPYLDALSTDLTELAEAGRLDPVVGRKDEIERVIQILSRRTKNNPALIGEPGVGKTAIAEGLAQRIVADDV
PDSLKGKRLVTLDMGALVAGTKYRGQFEERLKRVVDEIKESRCILFIDEFHTIIGAGGAEGTLDAANILKPALSRGELQC
IGATTLDEFRKYIEKDAALERRFQPVMVDEPTIEETIEILRGIKTRYEDFHQLQIEDEAITAAAVLSARYVPDRFLPDKA
IDLIDEASSRVRMYRSATPSALRDALRGLDAIRKEKDAALEEGQFEVVQDLRVREERMLQRITDLEDEEEKTRGSEQRKG
KPYVTQEDIAEVVAMWTGIPVMRLASEETERLMKMEDYLHERVIGQEEPISTIARAVRRARAGLKDPKRPIGSFIFLGPT
GVGKTLLAKALAEFMFGSEDALIKIDMSEFQERFNTSRLVGSPPGYVGYGEGGQLTDAVRRRPYSVVLFDEIEKAHPDTF
NLLLQVLEDGNLTDGKGRRVDFRNTVIIMTSNVGTEQIRRGSRIGFGGNRNTIDVEDTRKKVDDELKRMFRPEFLNRIDG
TIIFHPLTDIEIRNIARLEVNRVRKQLVDHQIDLLVTDETLDLLAKRGYDPTYGARPLRRVITNMIEDGLAEGLLQGRFK
DGDKIHIELEDNEVVLRSEREAAELENPSVEPEAELV

Sequences:

>Translated_837_residues
MGAYDKMSRRAKQVMSFAQEEARAFNHPYIGTEHLLLGLILEGEGVAARVLAELGVTITKARNAVEFIVGHGDGPRSTAE
IDLTARAKKVFEYAIDEARKLNHTYISTEHILLGLVRNAEGVATGVLEIMNVGLDQVRTQVMRMMRQGVGGSSTPSPSAG
GERQAKQSKTPYLDALSTDLTELAEAGRLDPVVGRKDEIERVIQILSRRTKNNPALIGEPGVGKTAIAEGLAQRIVADDV
PDSLKGKRLVTLDMGALVAGTKYRGQFEERLKRVVDEIKESRCILFIDEFHTIIGAGGAEGTLDAANILKPALSRGELQC
IGATTLDEFRKYIEKDAALERRFQPVMVDEPTIEETIEILRGIKTRYEDFHQLQIEDEAITAAAVLSARYVPDRFLPDKA
IDLIDEASSRVRMYRSATPSALRDALRGLDAIRKEKDAALEEGQFEVVQDLRVREERMLQRITDLEDEEEKTRGSEQRKG
KPYVTQEDIAEVVAMWTGIPVMRLASEETERLMKMEDYLHERVIGQEEPISTIARAVRRARAGLKDPKRPIGSFIFLGPT
GVGKTLLAKALAEFMFGSEDALIKIDMSEFQERFNTSRLVGSPPGYVGYGEGGQLTDAVRRRPYSVVLFDEIEKAHPDTF
NLLLQVLEDGNLTDGKGRRVDFRNTVIIMTSNVGTEQIRRGSRIGFGGNRNTIDVEDTRKKVDDELKRMFRPEFLNRIDG
TIIFHPLTDIEIRNIARLEVNRVRKQLVDHQIDLLVTDETLDLLAKRGYDPTYGARPLRRVITNMIEDGLAEGLLQGRFK
DGDKIHIELEDNEVVLRSEREAAELENPSVEPEAELV
>Mature_836_residues
GAYDKMSRRAKQVMSFAQEEARAFNHPYIGTEHLLLGLILEGEGVAARVLAELGVTITKARNAVEFIVGHGDGPRSTAEI
DLTARAKKVFEYAIDEARKLNHTYISTEHILLGLVRNAEGVATGVLEIMNVGLDQVRTQVMRMMRQGVGGSSTPSPSAGG
ERQAKQSKTPYLDALSTDLTELAEAGRLDPVVGRKDEIERVIQILSRRTKNNPALIGEPGVGKTAIAEGLAQRIVADDVP
DSLKGKRLVTLDMGALVAGTKYRGQFEERLKRVVDEIKESRCILFIDEFHTIIGAGGAEGTLDAANILKPALSRGELQCI
GATTLDEFRKYIEKDAALERRFQPVMVDEPTIEETIEILRGIKTRYEDFHQLQIEDEAITAAAVLSARYVPDRFLPDKAI
DLIDEASSRVRMYRSATPSALRDALRGLDAIRKEKDAALEEGQFEVVQDLRVREERMLQRITDLEDEEEKTRGSEQRKGK
PYVTQEDIAEVVAMWTGIPVMRLASEETERLMKMEDYLHERVIGQEEPISTIARAVRRARAGLKDPKRPIGSFIFLGPTG
VGKTLLAKALAEFMFGSEDALIKIDMSEFQERFNTSRLVGSPPGYVGYGEGGQLTDAVRRRPYSVVLFDEIEKAHPDTFN
LLLQVLEDGNLTDGKGRRVDFRNTVIIMTSNVGTEQIRRGSRIGFGGNRNTIDVEDTRKKVDDELKRMFRPEFLNRIDGT
IIFHPLTDIEIRNIARLEVNRVRKQLVDHQIDLLVTDETLDLLAKRGYDPTYGARPLRRVITNMIEDGLAEGLLQGRFKD
GDKIHIELEDNEVVLRSEREAAELENPSVEPEAELV

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=339, Percent_Identity=35.9882005899705, Blast_Score=206, Evalue=6e-53,
Organism=Escherichia coli, GI1788943, Length=877, Percent_Identity=46.0661345496009, Blast_Score=721, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=813, Percent_Identity=36.7773677736777, Blast_Score=465, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6320464, Length=712, Percent_Identity=46.9101123595506, Blast_Score=627, Evalue=1e-180,
Organism=Saccharomyces cerevisiae, GI6323002, Length=893, Percent_Identity=36.8421052631579, Blast_Score=533, Evalue=1e-152,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 93564; Mature: 93433

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00870 CLPAB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAYDKMSRRAKQVMSFAQEEARAFNHPYIGTEHLLLGLILEGEGVAARVLAELGVTITK
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEEEECCCCHHHHHHHHHCCHHHH
ARNAVEFIVGHGDGPRSTAEIDLTARAKKVFEYAIDEARKLNHTYISTEHILLGLVRNAE
HCCCEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHCCC
GVATGVLEIMNVGLDQVRTQVMRMMRQGVGGSSTPSPSAGGERQAKQSKTPYLDALSTDL
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHH
TELAEAGRLDPVVGRKDEIERVIQILSRRTKNNPALIGEPGVGKTAIAEGLAQRIVADDV
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHCCC
PDSLKGKRLVTLDMGALVAGTKYRGQFEERLKRVVDEIKESRCILFIDEFHTIIGAGGAE
CCCCCCCEEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCC
GTLDAANILKPALSRGELQCIGATTLDEFRKYIEKDAALERRFQPVMVDEPTIEETIEIL
CCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
RGIKTRYEDFHQLQIEDEAITAAAVLSARYVPDRFLPDKAIDLIDEASSRVRMYRSATPS
HHHHHHHHHHHHEEECHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHH
ALRDALRGLDAIRKEKDAALEEGQFEVVQDLRVREERMLQRITDLEDEEEKTRGSEQRKG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHCC
KPYVTQEDIAEVVAMWTGIPVMRLASEETERLMKMEDYLHERVIGQEEPISTIARAVRRA
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RAGLKDPKRPIGSFIFLGPTGVGKTLLAKALAEFMFGSEDALIKIDMSEFQERFNTSRLV
HCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCC
GSPPGYVGYGEGGQLTDAVRRRPYSVVLFDEIEKAHPDTFNLLLQVLEDGNLTDGKGRRV
CCCCCCCCCCCCCCHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEE
DFRNTVIIMTSNVGTEQIRRGSRIGFGGNRNTIDVEDTRKKVDDELKRMFRPEFLNRIDG
EECCEEEEEECCCCHHHHHCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHCHHHHHHCCC
TIIFHPLTDIEIRNIARLEVNRVRKQLVDHQIDLLVTDETLDLLAKRGYDPTYGARPLRR
EEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHCCCCCCCCCHHHHH
VITNMIEDGLAEGLLQGRFKDGDKIHIELEDNEVVLRSEREAAELENPSVEPEAELV
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
GAYDKMSRRAKQVMSFAQEEARAFNHPYIGTEHLLLGLILEGEGVAARVLAELGVTITK
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEEEECCCCHHHHHHHHHCCHHHH
ARNAVEFIVGHGDGPRSTAEIDLTARAKKVFEYAIDEARKLNHTYISTEHILLGLVRNAE
HCCCEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHCCC
GVATGVLEIMNVGLDQVRTQVMRMMRQGVGGSSTPSPSAGGERQAKQSKTPYLDALSTDL
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHH
TELAEAGRLDPVVGRKDEIERVIQILSRRTKNNPALIGEPGVGKTAIAEGLAQRIVADDV
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHCCC
PDSLKGKRLVTLDMGALVAGTKYRGQFEERLKRVVDEIKESRCILFIDEFHTIIGAGGAE
CCCCCCCEEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCC
GTLDAANILKPALSRGELQCIGATTLDEFRKYIEKDAALERRFQPVMVDEPTIEETIEIL
CCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
RGIKTRYEDFHQLQIEDEAITAAAVLSARYVPDRFLPDKAIDLIDEASSRVRMYRSATPS
HHHHHHHHHHHHEEECHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHH
ALRDALRGLDAIRKEKDAALEEGQFEVVQDLRVREERMLQRITDLEDEEEKTRGSEQRKG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHCC
KPYVTQEDIAEVVAMWTGIPVMRLASEETERLMKMEDYLHERVIGQEEPISTIARAVRRA
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RAGLKDPKRPIGSFIFLGPTGVGKTLLAKALAEFMFGSEDALIKIDMSEFQERFNTSRLV
HCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCC
GSPPGYVGYGEGGQLTDAVRRRPYSVVLFDEIEKAHPDTFNLLLQVLEDGNLTDGKGRRV
CCCCCCCCCCCCCCHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEE
DFRNTVIIMTSNVGTEQIRRGSRIGFGGNRNTIDVEDTRKKVDDELKRMFRPEFLNRIDG
EECCEEEEEECCCCHHHHHCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHCHHHHHHCCC
TIIFHPLTDIEIRNIARLEVNRVRKQLVDHQIDLLVTDETLDLLAKRGYDPTYGARPLRR
EEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHCCCCCCCCCHHHHH
VITNMIEDGLAEGLLQGRFKDGDKIHIELEDNEVVLRSEREAAELENPSVEPEAELV
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]