Click here to switch to the map view.

The map label for this gene is pbuG [H]

Identifier: 15927833

GI number: 15927833

Start: 2309578

End: 2310912

Strand: Reverse

Name: pbuG [H]

Synonym: SA2050

Alternate gene names: 15927833

Gene position: 2310912-2309578 (Counterclockwise)

Preceding gene: 15927834

Following gene: 15927831

Centisome position: 82.1

GC content: 35.43

Gene sequence:

>1335_bases
GTGAAAAACTATTTCCAGTTCGATAAATATGGAACAAACTTTAAAAGAGAAATCTTAGGCGGTATCACAACTTTCTTATC
TATGGCCTATATTTTAGCAGTTAACCCGCAAGTTTTAAGTTTAGCAGGTGTTAAAGGCGTATCAGAAGATATGAAAATGG
ACCAAGGTGCCATTTTTGTAGCGACTGCATTAGCAGCATTTGTAGGCTCGCTATTCATGGGACTAATAGCTAAATATCCA
ATCGCATTAGCACCAGGTATGGGATTAAATGCATTCTTTGCATTTACTGTTGTGTTAACCATGGGTATTCCTTGGCAAGT
TGGTTTAACAGGTGTTTTATTCTCAGGTATATTCTTTGCGATATTAACCGTCACAGGGTTTAGGGAAGTTATTATTAATG
CAATTCCTTATCAAATGAAGATGGCTGTTTCAGCAGGTATAGGATTATTCATTACATTTGTAGGTTTACAAAGTTCGGGT
ATTATAGTTAAAAATGAATCTACATTAGTAACATTGGGACATTTAACTGATCCACCAGTACTTTTGGCGATATTCGGTAT
CGTTATTACAGTTATTTTATATGCAATTAAATTGCCGGGTTCTATCTTTATCGGTATGATCATCACAGCAATCGTTGGTA
TGTTCACTGGATTGATTCAAATGCCATCTGGTATTGTAGGTAAGATTCCAAGTATTGAACCAACGTTCGGTGCTGCATTT
GAAGCGTTTAAAGACCCAAGTCAATTATTAACGATACAGTTCTTAATTGTTATTTTAACGTTCTTATTTATTGATTTCTT
TGATACAGCTGGTACATTAGTAGCTGTTGCTACTCAAGCAGGTATTATGAAAGATAATAAATTACCAAGAGCTGGTAGAG
CATTGTTCTCAGATTCTTTAGCTACGATTGTAGGATCAGTTTTTGGAACAACTACAACAACTTCTTATATCGAATCAACT
TCAGGTGTTGCTGTAGGTGCTAGAACAGGATTTGCTAGTATCGTAACAGGTTGTTGTTTCCTATTAGCGCTGTTCTTTAG
TCCGTTAATCGCTGTTGTAACAAGTGCAGTTACGACACCAGCTTTAGTGGTGGTAGGTGTATTAATGGCTGCAAACTTTG
CTGAGATAAACTGGAAAAGTTTTGAAGTTGCAGTGCCAGCATTCATTACAATCATTATGATGCCTTTATCATACTCAATT
GCAACTGGTATTGCGTGTGGATTTATTTTCTATCCAATTACAATGCTTATCTCTAAAAAACATAAAGAAGTACATCCGAT
AATGTATGTATTAATGGTACTATTCATTCTGTACTTCATATTTGTTCATGGTTAA

Upstream 100 bases:

>100_bases
AAAGTTGAATCAGAAAAACGAAAAGTTCGCTTTTGGTATTGTTTTTTATTAAGAATGATATTAAACTATTAAGGTATTTT
AAAAAAAGGAGCATCCATTC

Downstream 100 bases:

>100_bases
ATCCAGACACAAAAAACGACTGCCAATGATTGGTAGTCGTTTTTTCTTTGAAGTAAGGATAAAATAAGAAGCGAAATAAC
ATAAAGCAATATTATGAATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MKNYFQFDKYGTNFKREILGGITTFLSMAYILAVNPQVLSLAGVKGVSEDMKMDQGAIFVATALAAFVGSLFMGLIAKYP
IALAPGMGLNAFFAFTVVLTMGIPWQVGLTGVLFSGIFFAILTVTGFREVIINAIPYQMKMAVSAGIGLFITFVGLQSSG
IIVKNESTLVTLGHLTDPPVLLAIFGIVITVILYAIKLPGSIFIGMIITAIVGMFTGLIQMPSGIVGKIPSIEPTFGAAF
EAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAVATQAGIMKDNKLPRAGRALFSDSLATIVGSVFGTTTTTSYIEST
SGVAVGARTGFASIVTGCCFLLALFFSPLIAVVTSAVTTPALVVVGVLMAANFAEINWKSFEVAVPAFITIIMMPLSYSI
ATGIACGFIFYPITMLISKKHKEVHPIMYVLMVLFILYFIFVHG

Sequences:

>Translated_444_residues
MKNYFQFDKYGTNFKREILGGITTFLSMAYILAVNPQVLSLAGVKGVSEDMKMDQGAIFVATALAAFVGSLFMGLIAKYP
IALAPGMGLNAFFAFTVVLTMGIPWQVGLTGVLFSGIFFAILTVTGFREVIINAIPYQMKMAVSAGIGLFITFVGLQSSG
IIVKNESTLVTLGHLTDPPVLLAIFGIVITVILYAIKLPGSIFIGMIITAIVGMFTGLIQMPSGIVGKIPSIEPTFGAAF
EAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAVATQAGIMKDNKLPRAGRALFSDSLATIVGSVFGTTTTTSYIEST
SGVAVGARTGFASIVTGCCFLLALFFSPLIAVVTSAVTTPALVVVGVLMAANFAEINWKSFEVAVPAFITIIMMPLSYSI
ATGIACGFIFYPITMLISKKHKEVHPIMYVLMVLFILYFIFVHG
>Mature_444_residues
MKNYFQFDKYGTNFKREILGGITTFLSMAYILAVNPQVLSLAGVKGVSEDMKMDQGAIFVATALAAFVGSLFMGLIAKYP
IALAPGMGLNAFFAFTVVLTMGIPWQVGLTGVLFSGIFFAILTVTGFREVIINAIPYQMKMAVSAGIGLFITFVGLQSSG
IIVKNESTLVTLGHLTDPPVLLAIFGIVITVILYAIKLPGSIFIGMIITAIVGMFTGLIQMPSGIVGKIPSIEPTFGAAF
EAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAVATQAGIMKDNKLPRAGRALFSDSLATIVGSVFGTTTTTSYIEST
SGVAVGARTGFASIVTGCCFLLALFFSPLIAVVTSAVTTPALVVVGVLMAANFAEINWKSFEVAVPAFITIIMMPLSYSI
ATGIACGFIFYPITMLISKKHKEVHPIMYVLMVLFILYFIFVHG

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=444, Percent_Identity=40.3153153153153, Blast_Score=330, Evalue=9e-92,
Organism=Escherichia coli, GI1790150, Length=443, Percent_Identity=40.4063205417607, Blast_Score=320, Evalue=8e-89,
Organism=Escherichia coli, GI1790499, Length=449, Percent_Identity=32.0712694877506, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI48994909, Length=437, Percent_Identity=33.1807780320366, Blast_Score=202, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47396; Mature: 47396

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNYFQFDKYGTNFKREILGGITTFLSMAYILAVNPQVLSLAGVKGVSEDMKMDQGAIFV
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHCCCCHHHH
ATALAAFVGSLFMGLIAKYPIALAPGMGLNAFFAFTVVLTMGIPWQVGLTGVLFSGIFFA
HHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ILTVTGFREVIINAIPYQMKMAVSAGIGLFITFVGLQSSGIIVKNESTLVTLGHLTDPPV
HHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHCCCCCEEEECCCCEEEECCCCCCHH
LLAIFGIVITVILYAIKLPGSIFIGMIITAIVGMFTGLIQMPSGIVGKIPSIEPTFGAAF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
EAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAVATQAGIMKDNKLPRAGRALFSDSL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
ATIVGSVFGTTTTTSYIESTSGVAVGARTGFASIVTGCCFLLALFFSPLIAVVTSAVTTP
HHHHHHHHCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVVVGVLMAANFAEINWKSFEVAVPAFITIIMMPLSYSIATGIACGFIFYPITMLISKK
HHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKEVHPIMYVLMVLFILYFIFVHG
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNYFQFDKYGTNFKREILGGITTFLSMAYILAVNPQVLSLAGVKGVSEDMKMDQGAIFV
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHCCCCHHHH
ATALAAFVGSLFMGLIAKYPIALAPGMGLNAFFAFTVVLTMGIPWQVGLTGVLFSGIFFA
HHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ILTVTGFREVIINAIPYQMKMAVSAGIGLFITFVGLQSSGIIVKNESTLVTLGHLTDPPV
HHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHCCCCCEEEECCCCEEEECCCCCCHH
LLAIFGIVITVILYAIKLPGSIFIGMIITAIVGMFTGLIQMPSGIVGKIPSIEPTFGAAF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
EAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAVATQAGIMKDNKLPRAGRALFSDSL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
ATIVGSVFGTTTTTSYIESTSGVAVGARTGFASIVTGCCFLLALFFSPLIAVVTSAVTTP
HHHHHHHHCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVVVGVLMAANFAEINWKSFEVAVPAFITIIMMPLSYSIATGIACGFIFYPITMLISKK
HHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKEVHPIMYVLMVLFILYFIFVHG
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377; 11591660 [H]