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The map label for this gene is glpD

Identifier: 15926884

GI number: 15926884

Start: 1299244

End: 1300965

Strand: Direct

Name: glpD

Synonym: SA1142

Alternate gene names: 15926884

Gene position: 1299244-1300965 (Clockwise)

Preceding gene: 15926883

Following gene: 15926885

Centisome position: 46.16

GC content: 34.32

Gene sequence:

>1722_bases
ATGTGGGACAAGTCTCTCGTTTTTACATTTTTTAGGAGGCGTTTTGGAATGGCATTGTCTACTTTTAAGAGAGAACATAT
TAAAAAGAATTTAAGAAATGATGAATATGATTTAGTAATTATTGGTGGCGGTATTACAGGTGCAGGTATTGCACTAGACG
CGAGTGAAAGAGGAATGAAAGTTGCATTAGTTGAAATGCAAGACTTTGCACAAGGAACAAGCTCAAGATCTACAAAATTA
GTCCATGGTGGTTTACGTTACTTAAAACAATTCCAAATTGGAGTAGTTGCCGAAACTGGTAAAGAACGTGCGATTGTTTA
TGAAAATGGGCCTCATGTTACGACTCCAGAGTGGATGCTTTTACCAATGCATAAAGGTGGAACATTTGGTAAATTCTCAA
CATCAATTGGTTTAGGAATGTATGATCGTTTAGCAGGTGTTAAGAAGTCTGAACGTAAAAAAATGTTATCTAAAAAAGAA
ACTTTAGCTAAAGAACCATTAGTTAAAAAAGAAGGTCTAAAAGGCGGCGGTTACTATGTTGAATATCGTACTGACGATGC
GCGTTTAACTATTGAAGTTATGAAGCGTGCTGCTGAAAAAGGCGCAGAAATTATCAACTATACTAAATCTGAACACTTCA
CTTATGATAAAAATCAACAAGTAAATGGTGTTAAAGTTATAGATAAATTAACTAATGAAAATTATACAATTAAGGCTAAA
AAAGTGGTTAATGCAGCAGGCCCATGGGTTGATGATGTTAGAAGTGGTGATTATGCACGCAATAATAAAAAATTACGTTT
AACTAAAGGTGTACATGTTGTTATTGATCAATCAAAATTCCCATTAGGTCAAGCAGTATACTTTGATACTGAAAAAGATG
GAAGAATGATTTTTGCAATTCCACGTGAAGGAAAAGCGTATGTAGGTACTACAGATACATTCTATGACAATATCAAATCT
TCACCATTAACTACACAAGAAGACAGAGACTATTTAATCGATGCGATTAATTACATGTTCCCTAGTGTTAATGTTACAGA
TGAAGATATTGAATCAACATGGGCAGGAATTAGACCATTAATTTACGAAGAAGGCAAAGACCCTTCTGAAATCTCTCGTA
AGGATGAAATTTGGGAAGGTAAATCAGGTTTATTAACTATTGCAGGTGGTAAATTAACAGGCTATCGTCACATGGCTCAA
GACATTGTTGATTTAGTATCTAAACGCTTGAAAAAAGACTACGGTTTAACATTTAGTCCATGTAATACAAAAGGTCTGGC
AATTTCAGGTGGCGATGTAGGTGGTAGCAAGAACTTTGATGCGTTTGTAGAGCAAAAAGTAGATGTAGCTAAAGGATTCG
GCATTGATGAAGATGTTGCAAGACGTTTAGCATCTAAATATGGTTCAAATGTTGATGAATTGTTCAACATTGCGCAAACA
TCTCAATACCATGATAGCAAGTTACCATTAGAAATTTATGTAGAACTTGTTTATAGTATTCAACAAGAAATGGTATACAA
ACCTAACGATTTCTTAGTTCGTCGTTCTGGTAAAATGTATTTCAATATTAAAGATGTATTAGATTATAAAGATGCTGTCA
TCGATATTATGGCAGATATGCTTGATTACTCTCCAGCTCAAATTGAAGCATATACTGAAGAAGTTGAGCAAGCAATTAAA
GAAGCGCAACATGGAAATAATCAACCAGCAGTTAAAGAATAA

Upstream 100 bases:

>100_bases
TTAGACTTTTGTATAAACATTGTGATACAATCAATTTAAGTTAATATTTGAATCGAGAAACGAGAGATTTGTTCGAACAT
GTACAATTGAAGGATTGTTT

Downstream 100 bases:

>100_bases
TTAATTTGTACAATCATAAACTGGTGTCCTGTTTTAAGGGCATCAGTTTTTTTATACGAGATACATTAGTCAATTGAAAC
TATGCATCACTAAATGTATG

Product: aerobic glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MWDKSLVFTFFRRRFGMALSTFKREHIKKNLRNDEYDLVIIGGGITGAGIALDASERGMKVALVEMQDFAQGTSSRSTKL
VHGGLRYLKQFQIGVVAETGKERAIVYENGPHVTTPEWMLLPMHKGGTFGKFSTSIGLGMYDRLAGVKKSERKKMLSKKE
TLAKEPLVKKEGLKGGGYYVEYRTDDARLTIEVMKRAAEKGAEIINYTKSEHFTYDKNQQVNGVKVIDKLTNENYTIKAK
KVVNAAGPWVDDVRSGDYARNNKKLRLTKGVHVVIDQSKFPLGQAVYFDTEKDGRMIFAIPREGKAYVGTTDTFYDNIKS
SPLTTQEDRDYLIDAINYMFPSVNVTDEDIESTWAGIRPLIYEEGKDPSEISRKDEIWEGKSGLLTIAGGKLTGYRHMAQ
DIVDLVSKRLKKDYGLTFSPCNTKGLAISGGDVGGSKNFDAFVEQKVDVAKGFGIDEDVARRLASKYGSNVDELFNIAQT
SQYHDSKLPLEIYVELVYSIQQEMVYKPNDFLVRRSGKMYFNIKDVLDYKDAVIDIMADMLDYSPAQIEAYTEEVEQAIK
EAQHGNNQPAVKE

Sequences:

>Translated_573_residues
MWDKSLVFTFFRRRFGMALSTFKREHIKKNLRNDEYDLVIIGGGITGAGIALDASERGMKVALVEMQDFAQGTSSRSTKL
VHGGLRYLKQFQIGVVAETGKERAIVYENGPHVTTPEWMLLPMHKGGTFGKFSTSIGLGMYDRLAGVKKSERKKMLSKKE
TLAKEPLVKKEGLKGGGYYVEYRTDDARLTIEVMKRAAEKGAEIINYTKSEHFTYDKNQQVNGVKVIDKLTNENYTIKAK
KVVNAAGPWVDDVRSGDYARNNKKLRLTKGVHVVIDQSKFPLGQAVYFDTEKDGRMIFAIPREGKAYVGTTDTFYDNIKS
SPLTTQEDRDYLIDAINYMFPSVNVTDEDIESTWAGIRPLIYEEGKDPSEISRKDEIWEGKSGLLTIAGGKLTGYRHMAQ
DIVDLVSKRLKKDYGLTFSPCNTKGLAISGGDVGGSKNFDAFVEQKVDVAKGFGIDEDVARRLASKYGSNVDELFNIAQT
SQYHDSKLPLEIYVELVYSIQQEMVYKPNDFLVRRSGKMYFNIKDVLDYKDAVIDIMADMLDYSPAQIEAYTEEVEQAIK
EAQHGNNQPAVKE
>Mature_573_residues
MWDKSLVFTFFRRRFGMALSTFKREHIKKNLRNDEYDLVIIGGGITGAGIALDASERGMKVALVEMQDFAQGTSSRSTKL
VHGGLRYLKQFQIGVVAETGKERAIVYENGPHVTTPEWMLLPMHKGGTFGKFSTSIGLGMYDRLAGVKKSERKKMLSKKE
TLAKEPLVKKEGLKGGGYYVEYRTDDARLTIEVMKRAAEKGAEIINYTKSEHFTYDKNQQVNGVKVIDKLTNENYTIKAK
KVVNAAGPWVDDVRSGDYARNNKKLRLTKGVHVVIDQSKFPLGQAVYFDTEKDGRMIFAIPREGKAYVGTTDTFYDNIKS
SPLTTQEDRDYLIDAINYMFPSVNVTDEDIESTWAGIRPLIYEEGKDPSEISRKDEIWEGKSGLLTIAGGKLTGYRHMAQ
DIVDLVSKRLKKDYGLTFSPCNTKGLAISGGDVGGSKNFDAFVEQKVDVAKGFGIDEDVARRLASKYGSNVDELFNIAQT
SQYHDSKLPLEIYVELVYSIQQEMVYKPNDFLVRRSGKMYFNIKDVLDYKDAVIDIMADMLDYSPAQIEAYTEEVEQAIK
EAQHGNNQPAVKE

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=545, Percent_Identity=32.1100917431193, Blast_Score=266, Evalue=4e-71,
Organism=Homo sapiens, GI285002231, Length=545, Percent_Identity=32.1100917431193, Blast_Score=266, Evalue=4e-71,
Organism=Escherichia coli, GI2367226, Length=481, Percent_Identity=29.9376299376299, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1788574, Length=398, Percent_Identity=27.1356783919598, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17509253, Length=571, Percent_Identity=32.9246935201401, Blast_Score=253, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI115534726, Length=571, Percent_Identity=32.0490367775832, Blast_Score=248, Evalue=8e-66,
Organism=Saccharomyces cerevisiae, GI6322036, Length=592, Percent_Identity=30.5743243243243, Blast_Score=229, Evalue=1e-60,
Organism=Drosophila melanogaster, GI161077125, Length=565, Percent_Identity=32.7433628318584, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24653942, Length=565, Percent_Identity=32.7433628318584, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24653944, Length=565, Percent_Identity=32.7433628318584, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI20130025, Length=565, Percent_Identity=32.7433628318584, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24586295, Length=553, Percent_Identity=29.6564195298373, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI19921278, Length=553, Percent_Identity=28.2097649186257, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI45550977, Length=392, Percent_Identity=26.7857142857143, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 64464; Mature: 64464

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWDKSLVFTFFRRRFGMALSTFKREHIKKNLRNDEYDLVIIGGGITGAGIALDASERGMK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCCCCE
VALVEMQDFAQGTSSRSTKLVHGGLRYLKQFQIGVVAETGKERAIVYENGPHVTTPEWML
EEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCEEEEEECCCCCCCCCEEE
LPMHKGGTFGKFSTSIGLGMYDRLAGVKKSERKKMLSKKETLAKEPLVKKEGLKGGGYYV
EEECCCCCCCCCHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEE
EYRTDDARLTIEVMKRAAEKGAEIINYTKSEHFTYDKNQQVNGVKVIDKLTNENYTIKAK
EEECCCCEEHHHHHHHHHHCCCHHHCCCCCCCEECCCCCCCCHHHHHHHHCCCCEEEEEH
KVVNAAGPWVDDVRSGDYARNNKKLRLTKGVHVVIDQSKFPLGQAVYFDTEKDGRMIFAI
HHHCCCCCCHHHHCCCCCCCCCCEEEEECCEEEEEECCCCCCCCEEEEECCCCCEEEEEE
PREGKAYVGTTDTFYDNIKSSPLTTQEDRDYLIDAINYMFPSVNVTDEDIESTWAGIRPL
CCCCCEEECCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCC
IYEEGKDPSEISRKDEIWEGKSGLLTIAGGKLTGYRHMAQDIVDLVSKRLKKDYGLTFSP
EECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEECC
CNTKGLAISGGDVGGSKNFDAFVEQKVDVAKGFGIDEDVARRLASKYGSNVDELFNIAQT
CCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
SQYHDSKLPLEIYVELVYSIQQEMVYKPNDFLVRRSGKMYFNIKDVLDYKDAVIDIMADM
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHH
LDYSPAQIEAYTEEVEQAIKEAQHGNNQPAVKE
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MWDKSLVFTFFRRRFGMALSTFKREHIKKNLRNDEYDLVIIGGGITGAGIALDASERGMK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCCCCE
VALVEMQDFAQGTSSRSTKLVHGGLRYLKQFQIGVVAETGKERAIVYENGPHVTTPEWML
EEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCEEEEEECCCCCCCCCEEE
LPMHKGGTFGKFSTSIGLGMYDRLAGVKKSERKKMLSKKETLAKEPLVKKEGLKGGGYYV
EEECCCCCCCCCHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEE
EYRTDDARLTIEVMKRAAEKGAEIINYTKSEHFTYDKNQQVNGVKVIDKLTNENYTIKAK
EEECCCCEEHHHHHHHHHHCCCHHHCCCCCCCEECCCCCCCCHHHHHHHHCCCCEEEEEH
KVVNAAGPWVDDVRSGDYARNNKKLRLTKGVHVVIDQSKFPLGQAVYFDTEKDGRMIFAI
HHHCCCCCCHHHHCCCCCCCCCCEEEEECCEEEEEECCCCCCCCEEEEECCCCCEEEEEE
PREGKAYVGTTDTFYDNIKSSPLTTQEDRDYLIDAINYMFPSVNVTDEDIESTWAGIRPL
CCCCCEEECCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCC
IYEEGKDPSEISRKDEIWEGKSGLLTIAGGKLTGYRHMAQDIVDLVSKRLKKDYGLTFSP
EECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEECC
CNTKGLAISGGDVGGSKNFDAFVEQKVDVAKGFGIDEDVARRLASKYGSNVDELFNIAQT
CCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
SQYHDSKLPLEIYVELVYSIQQEMVYKPNDFLVRRSGKMYFNIKDVLDYKDAVIDIMADM
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHH
LDYSPAQIEAYTEEVEQAIKEAQHGNNQPAVKE
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA