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The map label for this gene is spoIIIE

Identifier: 15926859

GI number: 15926859

Start: 1270705

End: 1273071

Strand: Direct

Name: spoIIIE

Synonym: SA1119

Alternate gene names: 15926859

Gene position: 1270705-1273071 (Clockwise)

Preceding gene: 15926858

Following gene: 15926860

Centisome position: 45.14

GC content: 33.54

Gene sequence:

>2367_bases
TTGGCACAAGCAAAAAAGAAATCGACAGCTAAGAAAAAAACAGCATCAAAAAAAAGAACAAATTCAAGGAAAAAGAAGAA
TGATAATCCGATACGTTATGTCATAGCTATTTTAGTAGTTGTATTAATGGTGTTGGGTGTTTTCCAATTAGGAATAATCG
GTCGTCTAATTGACAGCTTCTTTAATTATTTATTTGGGTACAGTAGATATTTAACATATATTTTAGTACTCTTAGCAACT
GGTTTTATTACATACTCTAAACGTATTCCTAAAACTAGACGAACGGCTGGTTCGATTGTATTGCAAATTGCATTGCTATT
TGTATCACAGTTAGTTTTTCATTTTAATAGTGGTATCAAAGCTGAAAGAGAACCTGTACTTTCTTATGTATATCAGTCAT
ACCAACACAGTCATTTTCCAAATTTTGGTGGCGGTGTATTAGGTTTTTATTTATTAGAGTTAAGCGTACCTTTAATTTCA
TTATTTGGTGTATGTATTATTACTATTTTATTATTATGCTCAAGTGTTATTTTATTAACAAACCATCAACATCGTGATGT
TGCAAAAGTTGCACTGGAAAATATAAAAGCTTGGTTTGGTTCATTTAATGAAAAAATGTCGGAAAGAAACCAAGAAAAAC
AATTGAAGCGTGAAGAAAAAGCGAGACTTAAAGAAGAACAAAAGGCACGTCAAAATGAACAGCCACAAATAAAAGATGTG
AGTGATTTTACGGAAGTGCCTCAAGAAAGAGATATTCCAATTTATGGGCATACTGAAAATGAAAGTAAAAGCCAGTGTCA
ACCAAGTCGAAAAAAACGAGTGTTTGATGCAGAGAATAGTTCGAATAACATCGTAAATCATCAAGCAGATCAGCAAGAGC
AATTAACAGAACAAACTCATAACAGTGTTGAAAGTGAAAACACTATTGAAGAAGCTGGTGAAGTTACGAATGTATCGTAT
GTTGTTCCACCGTTAACTTTACTTAATCAACCTGCAAAACAAAAAGCAACATCTAAAGCTGAAGTACAACGTAAAGGACA
AGTACTAGAGAATACATTAAAAGATTTTGGGGTAAATGCAAAAGTGACACAAATTAAAATTGGTCCTGCAGTAACTCAAT
ATGAAATTCAACCAGCTCAAGGGGTTAAAGTGAGTAAAATTGTAAACTTGCATAATGATATTGCATTAGCTTTAGCAGCA
AAAGATGTTAGAATCGAAGCACCAATACCTGGTCGCTCTGCAGTAGGTATTGAAGTGCCAAATGAGAAAATTTCATTAGT
TTCACTAAAAGAAGTTTTAGATGAAAAATTCCCGTCTAATAATAAACTAGAAGTTGGATTAGGAAGAGATATATCAGGTG
ATCCAATTACTGTTCCACTAAATGAAATGCCACACTTATTGGTGGCAGGATCGACGGGTAGTGGTAAATCTGTTTGTATA
AATGGTATTATTACAAGTATTTTATTAAATGCTAAGCCGCATGAAGTTAAACTTATGTTAATCGATCCGAAAATGGTTGA
ACTAAATGTTTATAACGGAATTCCACATTTATTAATTCCGGTTGTTACAAATCCTCATAAAGCTGCTCAAGCTTTAGAAA
AAATTGTAGCTGAGATGGAAAGACGTTATGATTTATTCCAACATTCATCAACTAGAAATATTAAAGGTTATAACGAATTA
ATCCGTAAGCAAAATCAAGAATTAGATGAGAAGCAACCAGAATTACCTTATATCGTTGTTATTGTAGATGAGCTTGCAGA
TTTAATGATGGTAGCTGGTAAAGAAGTTGAAAATGCGATTCAACGTATCACACAAATGGCACGTGCAGCAGGTATACATT
TGATTGTAGCAACACAAAGACCTTCTGTGGATGTAATTACAGGTATCATTAAAAATAACATTCCATCTAGAATTGCTTTT
GCTGTGAGTTCTCAAACAGATTCAAGAACTATTATTGGTACTGGCGGTGCAGAAAAGTTACTTGGTAAAGGTGACATGTT
ATACGTTGGAAATGGTGATTCATCACAAACACGTATTCAAGGGGCGTTTTTAAGTGACCAAGAGGTGCAAGATGTTGTAA
ATTATGTAGTAGAACAACAACAGGCAAATTATGTAAAAGAAATGGAACCAGATGCACCAGTGGATAAATCGGAAATGAAA
AGTGAAGATGCTTTATATGATGAAGCGTATTTGTTTGTTGTTGAACAACAAAAGGCAAGTACATCATTGTTACAACGCCA
ATTTAGAATTGGTTATAATAGAGCATCTAGGTTGATGGATGATTTAGAACGCAATCAGGTAATCGGTCCACAAAAAGGAA
GCAAGCCTAGACAAGTTTTAATAGATCTTAATAATGACGAGGTGTAA

Upstream 100 bases:

>100_bases
CTCTTTCATCGTCTGTTTGGACTACATATTCTAAACATCAAATAGGAAATTATATATAATAACGTCGTTTTAACTAAGGC
AACATAAGGAGGTGCGTCAA

Downstream 100 bases:

>100_bases
AAAAATGTCAGAAATGAATGCGGTATATAACGTTAAACAATACATTTTAAATTTGATTATGCAAAATAAATTGGAATATG
GTGACCAACTTCCAAGTAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 788; Mature: 787

Protein sequence:

>788_residues
MAQAKKKSTAKKKTASKKRTNSRKKKNDNPIRYVIAILVVVLMVLGVFQLGIIGRLIDSFFNYLFGYSRYLTYILVLLAT
GFITYSKRIPKTRRTAGSIVLQIALLFVSQLVFHFNSGIKAEREPVLSYVYQSYQHSHFPNFGGGVLGFYLLELSVPLIS
LFGVCIITILLLCSSVILLTNHQHRDVAKVALENIKAWFGSFNEKMSERNQEKQLKREEKARLKEEQKARQNEQPQIKDV
SDFTEVPQERDIPIYGHTENESKSQCQPSRKKRVFDAENSSNNIVNHQADQQEQLTEQTHNSVESENTIEEAGEVTNVSY
VVPPLTLLNQPAKQKATSKAEVQRKGQVLENTLKDFGVNAKVTQIKIGPAVTQYEIQPAQGVKVSKIVNLHNDIALALAA
KDVRIEAPIPGRSAVGIEVPNEKISLVSLKEVLDEKFPSNNKLEVGLGRDISGDPITVPLNEMPHLLVAGSTGSGKSVCI
NGIITSILLNAKPHEVKLMLIDPKMVELNVYNGIPHLLIPVVTNPHKAAQALEKIVAEMERRYDLFQHSSTRNIKGYNEL
IRKQNQELDEKQPELPYIVVIVDELADLMMVAGKEVENAIQRITQMARAAGIHLIVATQRPSVDVITGIIKNNIPSRIAF
AVSSQTDSRTIIGTGGAEKLLGKGDMLYVGNGDSSQTRIQGAFLSDQEVQDVVNYVVEQQQANYVKEMEPDAPVDKSEMK
SEDALYDEAYLFVVEQQKASTSLLQRQFRIGYNRASRLMDDLERNQVIGPQKGSKPRQVLIDLNNDEV

Sequences:

>Translated_788_residues
MAQAKKKSTAKKKTASKKRTNSRKKKNDNPIRYVIAILVVVLMVLGVFQLGIIGRLIDSFFNYLFGYSRYLTYILVLLAT
GFITYSKRIPKTRRTAGSIVLQIALLFVSQLVFHFNSGIKAEREPVLSYVYQSYQHSHFPNFGGGVLGFYLLELSVPLIS
LFGVCIITILLLCSSVILLTNHQHRDVAKVALENIKAWFGSFNEKMSERNQEKQLKREEKARLKEEQKARQNEQPQIKDV
SDFTEVPQERDIPIYGHTENESKSQCQPSRKKRVFDAENSSNNIVNHQADQQEQLTEQTHNSVESENTIEEAGEVTNVSY
VVPPLTLLNQPAKQKATSKAEVQRKGQVLENTLKDFGVNAKVTQIKIGPAVTQYEIQPAQGVKVSKIVNLHNDIALALAA
KDVRIEAPIPGRSAVGIEVPNEKISLVSLKEVLDEKFPSNNKLEVGLGRDISGDPITVPLNEMPHLLVAGSTGSGKSVCI
NGIITSILLNAKPHEVKLMLIDPKMVELNVYNGIPHLLIPVVTNPHKAAQALEKIVAEMERRYDLFQHSSTRNIKGYNEL
IRKQNQELDEKQPELPYIVVIVDELADLMMVAGKEVENAIQRITQMARAAGIHLIVATQRPSVDVITGIIKNNIPSRIAF
AVSSQTDSRTIIGTGGAEKLLGKGDMLYVGNGDSSQTRIQGAFLSDQEVQDVVNYVVEQQQANYVKEMEPDAPVDKSEMK
SEDALYDEAYLFVVEQQKASTSLLQRQFRIGYNRASRLMDDLERNQVIGPQKGSKPRQVLIDLNNDEV
>Mature_787_residues
AQAKKKSTAKKKTASKKRTNSRKKKNDNPIRYVIAILVVVLMVLGVFQLGIIGRLIDSFFNYLFGYSRYLTYILVLLATG
FITYSKRIPKTRRTAGSIVLQIALLFVSQLVFHFNSGIKAEREPVLSYVYQSYQHSHFPNFGGGVLGFYLLELSVPLISL
FGVCIITILLLCSSVILLTNHQHRDVAKVALENIKAWFGSFNEKMSERNQEKQLKREEKARLKEEQKARQNEQPQIKDVS
DFTEVPQERDIPIYGHTENESKSQCQPSRKKRVFDAENSSNNIVNHQADQQEQLTEQTHNSVESENTIEEAGEVTNVSYV
VPPLTLLNQPAKQKATSKAEVQRKGQVLENTLKDFGVNAKVTQIKIGPAVTQYEIQPAQGVKVSKIVNLHNDIALALAAK
DVRIEAPIPGRSAVGIEVPNEKISLVSLKEVLDEKFPSNNKLEVGLGRDISGDPITVPLNEMPHLLVAGSTGSGKSVCIN
GIITSILLNAKPHEVKLMLIDPKMVELNVYNGIPHLLIPVVTNPHKAAQALEKIVAEMERRYDLFQHSSTRNIKGYNELI
RKQNQELDEKQPELPYIVVIVDELADLMMVAGKEVENAIQRITQMARAAGIHLIVATQRPSVDVITGIIKNNIPSRIAFA
VSSQTDSRTIIGTGGAEKLLGKGDMLYVGNGDSSQTRIQGAFLSDQEVQDVVNYVVEQQQANYVKEMEPDAPVDKSEMKS
EDALYDEAYLFVVEQQKASTSLLQRQFRIGYNRASRLMDDLERNQVIGPQKGSKPRQVLIDLNNDEV

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=484, Percent_Identity=46.900826446281, Blast_Score=407, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 88009; Mature: 87878

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EECCCCCC
>Mature Secondary Structure 
AQAKKKSTAKKKTASKKRTNSRKKKNDNPIRYVIAILVVVLMVLGVFQLGIIGRLIDSF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNYLFGYSRYLTYILVLLATGFITYSKRIPKTRRTAGSIVLQIALLFVSQLVFHFNSGIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AEREPVLSYVYQSYQHSHFPNFGGGVLGFYLLELSVPLISLFGVCIITILLLCSSVILLT
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NHQHRDVAKVALENIKAWFGSFNEKMSERNQEKQLKREEKARLKEEQKARQNEQPQIKDV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SDFTEVPQERDIPIYGHTENESKSQCQPSRKKRVFDAENSSNNIVNHQADQQEQLTEQTH
HHHHHCCCCCCCCEECCCCCCCHHHCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
NSVESENTIEEAGEVTNVSYVVPPLTLLNQPAKQKATSKAEVQRKGQVLENTLKDFGVNA
HCCCCHHHHHHCCCCCCCEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KVTQIKIGPAVTQYEIQPAQGVKVSKIVNLHNDIALALAAKDVRIEAPIPGRSAVGIEVP
EEEEEEECCCEEEEEECCCCCCCHHHHHHHCCCEEEEEEECCEEEECCCCCCCEEEEECC
NEKISLVSLKEVLDEKFPSNNKLEVGLGRDISGDPITVPLNEMPHLLVAGSTGSGKSVCI
CCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEECCCCCCEEEECCCCCCCHHHH
NGIITSILLNAKPHEVKLMLIDPKMVELNVYNGIPHLLIPVVTNPHKAAQALEKIVAEME
HHHHHHHHHCCCCCEEEEEEECCEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHH
RRYDLFQHSSTRNIKGYNELIRKQNQELDEKQPELPYIVVIVDELADLMMVAGKEVENAI
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHCHHHHHHH
QRITQMARAAGIHLIVATQRPSVDVITGIIKNNIPSRIAFAVSSQTDSRTIIGTGGAEKL
HHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEECCCHHHH
LGKGDMLYVGNGDSSQTRIQGAFLSDQEVQDVVNYVVEQQQANYVKEMEPDAPVDKSEMK
HCCCCEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHC
SEDALYDEAYLFVVEQQKASTSLLQRQFRIGYNRASRLMDDLERNQVIGPQKGSKPRQVL
CHHHHHCCEEEEEEECHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
IDLNNDEV
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA