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The map label for this gene is nusA

Identifier: 15926849

GI number: 15926849

Start: 1258966

End: 1260141

Strand: Direct

Name: nusA

Synonym: SA1109

Alternate gene names: 15926849

Gene position: 1258966-1260141 (Clockwise)

Preceding gene: 15926848

Following gene: 15926850

Centisome position: 44.73

GC content: 35.46

Gene sequence:

>1176_bases
GTGTCAAGTAATGAATTATTATTAGCTACTGAGTATTTAGAAAAAGAAAAGAAGATTCCTAGAGCAGTATTAATTGATGC
TATTGAAGCAGCTTTAATTACTGCATACAAAAAGAATTATGATAGTGCAAGAAATGTCCGTGTGGAATTAAATATGGATC
AAGGTACTTTCAAAGTTATCGCTCGTAAAGATGTTGTTGAAGAAGTATTTGACGACAGAGATGAAGTGGATTTAAGTACA
GCGCTTGTTAAAAACCCTGCATATGAAATTGGTGATATATACGAAGAAGATGTAACACCTAAAGATTTTGGTCGTGTAGG
TGCTCAAGCAGCGAAACAAGCAGTAATGCAACGTCTTCGTGATGCTGAACGTGAAATTTTATTTGAAGAATTTATAGACA
AAGAAGAAGACATACTTACTGGAATTATTGACCGTGTTGACCATCGTTATGTATATGTGAATTTAGGTCGTATCGAAGCT
GTTTTATCTGAAGCAGAAAGAAGTCCTAACGAAAAATATATTCCTAACGAACGTATCAAAGTATATGTTAACAAAGTGGA
ACAAACGACAAAAGGTCCTCAAATCTATGTTTCTCGTAGCCATCCAGGTTTATTAAAACGTTTATTTGAACAAGAAGTTC
CAGAAATTTACGATGGTACTGTAATTGTTAAATCAGTAGCACGTGAAGCTGGCGATCGCTCTAAAATTAGTGTCTTCTCT
GAAAACAATGATATAGATGCTGTTGGTGCATGTGTTGGTGCTAAAGGCGCACGTGTTGAAGCTGTTGTTGAAGAGCTAGG
TGGCGAAAAAATCGACATCGTTCAATGGAATGAAGATCCAAAAGTATTTGTAAAAAATGCTTTAAGCCCTTCTCAAGTTT
TAGAAGTTATTGTTGATGAAACAAATCAATCTACAGTAGTTGTTGTTCCTGATTATCAATTGTCATTAGCGATTGGTAAA
AGAGGACAAAACGCACGTCTAGCTGCTAAATTAACCGGCTGGAAAATTGATATTAAATCAGAAACAGATGCGCGTGAAGC
GGGTATCTATCCAGTAGTTGAAGCTGAAAAAGTAACTGAAGAAGATATTGCTTTAGAAGATGCTGACACAACAGAATCAA
CCGAAGAGGTAAATGATGTTTCAGTTGAAACAAATGTAGAGAAAGAATCTGAATAA

Upstream 100 bases:

>100_bases
TTAAAATCAAAGCAAGAACGAAAGATATAGAGATACCGAGAGACAAAATAGCAAAAGCACGTCACGCAGTTATGATTTAA
CGTGATGAGGAGGAAAAAAC

Downstream 100 bases:

>100_bases
TAGGTTGGAGTGAAGTATCTATGAAAAAGAAAAAAATTCCGATGCGAAAATGTATTCTTTCAAATGAAATGCATCCCAAA
AAAGATATGATTCGTGTTGT

Product: transcription elongation factor NusA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSSNELLLATEYLEKEKKIPRAVLIDAIEAALITAYKKNYDSARNVRVELNMDQGTFKVIARKDVVEEVFDDRDEVDLST
ALVKNPAYEIGDIYEEDVTPKDFGRVGAQAAKQAVMQRLRDAEREILFEEFIDKEEDILTGIIDRVDHRYVYVNLGRIEA
VLSEAERSPNEKYIPNERIKVYVNKVEQTTKGPQIYVSRSHPGLLKRLFEQEVPEIYDGTVIVKSVAREAGDRSKISVFS
ENNDIDAVGACVGAKGARVEAVVEELGGEKIDIVQWNEDPKVFVKNALSPSQVLEVIVDETNQSTVVVVPDYQLSLAIGK
RGQNARLAAKLTGWKIDIKSETDAREAGIYPVVEAEKVTEEDIALEDADTTESTEEVNDVSVETNVEKESE

Sequences:

>Translated_391_residues
MSSNELLLATEYLEKEKKIPRAVLIDAIEAALITAYKKNYDSARNVRVELNMDQGTFKVIARKDVVEEVFDDRDEVDLST
ALVKNPAYEIGDIYEEDVTPKDFGRVGAQAAKQAVMQRLRDAEREILFEEFIDKEEDILTGIIDRVDHRYVYVNLGRIEA
VLSEAERSPNEKYIPNERIKVYVNKVEQTTKGPQIYVSRSHPGLLKRLFEQEVPEIYDGTVIVKSVAREAGDRSKISVFS
ENNDIDAVGACVGAKGARVEAVVEELGGEKIDIVQWNEDPKVFVKNALSPSQVLEVIVDETNQSTVVVVPDYQLSLAIGK
RGQNARLAAKLTGWKIDIKSETDAREAGIYPVVEAEKVTEEDIALEDADTTESTEEVNDVSVETNVEKESE
>Mature_390_residues
SSNELLLATEYLEKEKKIPRAVLIDAIEAALITAYKKNYDSARNVRVELNMDQGTFKVIARKDVVEEVFDDRDEVDLSTA
LVKNPAYEIGDIYEEDVTPKDFGRVGAQAAKQAVMQRLRDAEREILFEEFIDKEEDILTGIIDRVDHRYVYVNLGRIEAV
LSEAERSPNEKYIPNERIKVYVNKVEQTTKGPQIYVSRSHPGLLKRLFEQEVPEIYDGTVIVKSVAREAGDRSKISVFSE
NNDIDAVGACVGAKGARVEAVVEELGGEKIDIVQWNEDPKVFVKNALSPSQVLEVIVDETNQSTVVVVPDYQLSLAIGKR
GQNARLAAKLTGWKIDIKSETDAREAGIYPVVEAEKVTEEDIALEDADTTESTEEVNDVSVETNVEKESE

Specific function: Participates in both the termination and antitermination of transcription. Interacts with RNA polymerase and binds RNA [H]

COG id: COG0195

COG function: function code K; Transcription elongation factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI1789560, Length=342, Percent_Identity=38.0116959064327, Blast_Score=252, Evalue=3e-68,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1612 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004087
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004088
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013735
- InterPro:   IPR010213 [H]

Pfam domain/function: PF08529 NusA_N; PF00575 S1 [H]

EC number: NA

Molecular weight: Translated: 43755; Mature: 43624

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS50084 KH_TYPE_1 ; PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNELLLATEYLEKEKKIPRAVLIDAIEAALITAYKKNYDSARNVRVELNMDQGTFKVI
CCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEH
ARKDVVEEVFDDRDEVDLSTALVKNPAYEIGDIYEEDVTPKDFGRVGAQAAKQAVMQRLR
HHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DAEREILFEEFIDKEEDILTGIIDRVDHRYVYVNLGRIEAVLSEAERSPNEKYIPNERIK
HHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCEE
VYVNKVEQTTKGPQIYVSRSHPGLLKRLFEQEVPEIYDGTVIVKSVAREAGDRSKISVFS
EEEEHHHHCCCCCEEEEECCCCHHHHHHHHHHCCHHHCCHHHHHHHHHHCCCCCEEEEEE
ENNDIDAVGACVGAKGARVEAVVEELGGEKIDIVQWNEDPKVFVKNALSPSQVLEVIVDE
CCCCCCHHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHCCCCHHHHHHHHHCC
TNQSTVVVVPDYQLSLAIGKRGQNARLAAKLTGWKIDIKSETDAREAGIYPVVEAEKVTE
CCCCEEEEECCCEEEEEECCCCCCCEEEEEEECEEEEECCCCCHHHCCCCCEEEHHHCCH
EDIALEDADTTESTEEVNDVSVETNVEKESE
HHCEECCCCCCCCHHHHCCEEEECCCCCCCC
>Mature Secondary Structure 
SSNELLLATEYLEKEKKIPRAVLIDAIEAALITAYKKNYDSARNVRVELNMDQGTFKVI
CCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEH
ARKDVVEEVFDDRDEVDLSTALVKNPAYEIGDIYEEDVTPKDFGRVGAQAAKQAVMQRLR
HHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DAEREILFEEFIDKEEDILTGIIDRVDHRYVYVNLGRIEAVLSEAERSPNEKYIPNERIK
HHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCEE
VYVNKVEQTTKGPQIYVSRSHPGLLKRLFEQEVPEIYDGTVIVKSVAREAGDRSKISVFS
EEEEHHHHCCCCCEEEEECCCCHHHHHHHHHHCCHHHCCHHHHHHHHHHCCCCCEEEEEE
ENNDIDAVGACVGAKGARVEAVVEELGGEKIDIVQWNEDPKVFVKNALSPSQVLEVIVDE
CCCCCCHHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHCCCCHHHHHHHHHCC
TNQSTVVVVPDYQLSLAIGKRGQNARLAAKLTGWKIDIKSETDAREAGIYPVVEAEKVTE
CCCCEEEEECCCEEEEEECCCCCCCEEEEEEECEEEEECCCCCHHHCCCCCEEEHHHCCH
EDIALEDADTTESTEEVNDVSVETNVEKESE
HHCEECCCCCCCCHHHHCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8491709; 9384377 [H]