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The map label for this gene is yggV [C]

Identifier: 15926735

GI number: 15926735

Start: 1131655

End: 1132242

Strand: Direct

Name: yggV [C]

Synonym: SA0998

Alternate gene names: 15926735

Gene position: 1131655-1132242 (Clockwise)

Preceding gene: 15926734

Following gene: 15926736

Centisome position: 40.2

GC content: 32.82

Gene sequence:

>588_bases
ATGAAAGAGATTGTTATTGCATCGAATAATCAAGGGAAAATAAATGACTTTAAAGTAATATTTCCAGATTACCACGTAAT
AGGTATTTCAGAACTAATACCAGATTTTGATGTGGAAGAAACAGGATCAACATTTGAAGAAAATGCTATATTAAAATCAG
AAGCTGCTGCAAAAGCATTGAATAAAACTGTCATAGCTGATGACAGTGGACTAGAAGTTTTTGCATTAAATGGTGAGCCA
GGTATATACTCTGCACGTTATGCTGGTGAAAATAAAAGCGATGAAGCAAATATTGAAAAATTATTAAATAAGCTTGGTAA
TACAACTGATCGTCGTGCGCAATTTGTTTGTGTCATAAGTATGAGTGGCCCTGATATGGAAACAAAAGTATTTAAAGGTA
CTGTTTCAGGTGAAATTGCAGATGGAAAATATGGCGAAAATGGTTTCGGATATGATCCGATATTTTATGTACCGAAATTA
GATAAAACCATGGCTCAACTTTCAAAAGAACAAAAAGGGCAAATTAGTCATAGACGAAATGCGATTAATTTACTTCAAGC
TTTTCTTGAAGGTGAAAAAAATGTCTAA

Upstream 100 bases:

>100_bases
CAACAGGTGATCCTACTCACATTACTAACATTATCAAAGAGTGGTTAAATTTATCTGTCAATGTGGAACGTATATCAGTG
AATGACTAGGAGGATTTTTA

Downstream 100 bases:

>100_bases
ATGGATTATTGTGAGTGATAACCATACTGAATCAGGCGTTTTATATCAAATTTATGAAATGCACCCAGATGCAGATGTAT
ATTTACATTTAGGAGATTCA

Product: nucleoside-triphosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKALNKTVIADDSGLEVFALNGEP
GIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKL
DKTMAQLSKEQKGQISHRRNAINLLQAFLEGEKNV

Sequences:

>Translated_195_residues
MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKALNKTVIADDSGLEVFALNGEP
GIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKL
DKTMAQLSKEQKGQISHRRNAINLLQAFLEGEKNV
>Mature_195_residues
MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKALNKTVIADDSGLEVFALNGEP
GIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKL
DKTMAQLSKEQKGQISHRRNAINLLQAFLEGEKNV

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=191, Percent_Identity=27.7486910994764, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789324, Length=191, Percent_Identity=43.979057591623, Blast_Score=149, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17556833, Length=191, Percent_Identity=27.2251308900524, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920712, Length=191, Percent_Identity=32.4607329842932, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21417; Mature: 21417

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKAL
CCEEEEEECCCCCCCEEEEECCCEEEEEHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHH
NKTVIADDSGLEVFALNGEPGIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVIS
CCEEEECCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEE
MSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKLDKTMAQLSKEQKGQISHRRN
CCCCCCCCEEEECCCCCEECCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHH
AINLLQAFLEGEKNV
HHHHHHHHHCCCCCC
>Mature Secondary Structure
MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKAL
CCEEEEEECCCCCCCEEEEECCCEEEEEHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHH
NKTVIADDSGLEVFALNGEPGIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVIS
CCEEEECCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEE
MSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKLDKTMAQLSKEQKGQISHRRN
CCCCCCCCEEEECCCCCEECCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHH
AINLLQAFLEGEKNV
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA