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The map label for this gene is lacC

Identifier: 15925183

GI number: 15925183

Start: 2336622

End: 2337554

Strand: Reverse

Name: lacC

Synonym: SAV2193

Alternate gene names: 15925183

Gene position: 2337554-2336622 (Counterclockwise)

Preceding gene: 15925184

Following gene: 15925182

Centisome position: 81.21

GC content: 35.16

Gene sequence:

>933_bases
ATGATTTTAACTTTAACATTAAATCCATCCGTTGATATTTCATATCCATTAACAGCATTGAAATTAGATGATGTTAATCG
TGTTCAAGAAGTAAGTAAAACAGCTGGTGGTAAAGGTTTAAATGTAACAAGAGTACTTGCGCAAGTAGGCGAGCCAGTCC
TTGCGAGTGGTTTTATTGGCGGTGAATTAGGTCAATTTATTGCTAAAAAATTAGATCATGCCGACATCAAGCATGCATTT
TATAACATTAAGGGTGAAACACGAAACTGCATTGCAATTTTACATGAAGGGCAACAAACAGAAATTTTAGAGCAGGGACC
GGAGATTGATAATCAAGAGGCTGCAGGATTTATTAAACATTTTGAACAATTATTAGAAAAAGTTGAAGCAGTTGCTATTT
CAGGTAGCTTACCTAAAGGATTAAATCAAGATTATTATGCACAAATTATTGAACGATGCCAAAACAAAGGTGTGCCTGTG
ATATTGGACTGCTCGGGTGCAACTTTGCAAACAGTTTTGGAAAATCCATACAAACCAACAGTCATTAAACCAAACATTTC
TGAACTATATCAATTGCTTAACCAGCCACTTGATGAAAGTTTAGAAAGTTTGAAACAGGCAGTGTCACAACCCTTATTCG
AAGGGATTGAGTGGATTATTGTGTCTTTAGGTGCACAAGGTGCATTCGCTAAGCACAATCATACATTCTATAGAGTGAAT
ATTCCGACAATAAACGTATTAAATCCGGTTGGTTCAGGTGATTCTACAGTTGCTGGAATTACTTCAGCAATTCTCAATCA
TGAAAACGACCACGATTTACTAAAAAAAGCTAATACTTTAGGCATGCTGAATGCGCAAGAAGCACAAACAGGATATGTCA
ATTTAAATAATTATGATGAATTATTCAATCAAATTGAAGTTTTAGAGGTGTAA

Upstream 100 bases:

>100_bases
TTTAGAAACAAGCAATGCAGATCAAGCTGATCCACATTTCTTTGATGAATTCTTAGAAAAATGGGACAGAGGCGAATACC
ACGATTAAGGGACGACACAT

Downstream 100 bases:

>100_bases
ATAATGTCAAAATCTAATCAAAAAATCGCATCAATTGAACAATTAAGTAATAACGAAGGTATCATTTCTGCATTAGCATT
TGACCAACGTGGTGCTTTAA

Product: tagatose-6-phosphate kinase

Products: NA

Alternate protein names: Phosphotagatokinase

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MILTLTLNPSVDISYPLTALKLDDVNRVQEVSKTAGGKGLNVTRVLAQVGEPVLASGFIGGELGQFIAKKLDHADIKHAF
YNIKGETRNCIAILHEGQQTEILEQGPEIDNQEAAGFIKHFEQLLEKVEAVAISGSLPKGLNQDYYAQIIERCQNKGVPV
ILDCSGATLQTVLENPYKPTVIKPNISELYQLLNQPLDESLESLKQAVSQPLFEGIEWIIVSLGAQGAFAKHNHTFYRVN
IPTINVLNPVGSGDSTVAGITSAILNHENDHDLLKKANTLGMLNAQEAQTGYVNLNNYDELFNQIEVLEV

Sequences:

>Translated_310_residues
MILTLTLNPSVDISYPLTALKLDDVNRVQEVSKTAGGKGLNVTRVLAQVGEPVLASGFIGGELGQFIAKKLDHADIKHAF
YNIKGETRNCIAILHEGQQTEILEQGPEIDNQEAAGFIKHFEQLLEKVEAVAISGSLPKGLNQDYYAQIIERCQNKGVPV
ILDCSGATLQTVLENPYKPTVIKPNISELYQLLNQPLDESLESLKQAVSQPLFEGIEWIIVSLGAQGAFAKHNHTFYRVN
IPTINVLNPVGSGDSTVAGITSAILNHENDHDLLKKANTLGMLNAQEAQTGYVNLNNYDELFNQIEVLEV
>Mature_310_residues
MILTLTLNPSVDISYPLTALKLDDVNRVQEVSKTAGGKGLNVTRVLAQVGEPVLASGFIGGELGQFIAKKLDHADIKHAF
YNIKGETRNCIAILHEGQQTEILEQGPEIDNQEAAGFIKHFEQLLEKVEAVAISGSLPKGLNQDYYAQIIERCQNKGVPV
ILDCSGATLQTVLENPYKPTVIKPNISELYQLLNQPLDESLESLKQAVSQPLFEGIEWIIVSLGAQGAFAKHNHTFYRVN
IPTINVLNPVGSGDSTVAGITSAILNHENDHDLLKKANTLGMLNAQEAQTGYVNLNNYDELFNQIEVLEV

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family. LacC subfamily

Homologues:

Organism=Escherichia coli, GI1788493, Length=275, Percent_Identity=27.6363636363636, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788017, Length=280, Percent_Identity=28.9285714285714, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LACC_STAA1 (A7X575)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442767.1
- ProteinModelPortal:   A7X575
- SMR:   A7X575
- STRING:   A7X575
- EnsemblBacteria:   EBSTAT00000003735
- GeneID:   5561580
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2177
- eggNOG:   COG1105
- GeneTree:   EBGT00050000023902
- HOGENOM:   HBG670529
- OMA:   HSHAAGK
- ProtClustDB:   PRK13508
- BioCyc:   SAUR418127:SAHV_2177-MONOMER
- HAMAP:   MF_01557
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR005926
- InterPro:   IPR017583
- TIGRFAMs:   TIGR03168
- TIGRFAMs:   TIGR01231

Pfam domain/function: PF00294 PfkB

EC number: =2.7.1.144

Molecular weight: Translated: 33895; Mature: 33895

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00583 PFKB_KINASES_1; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILTLTLNPSVDISYPLTALKLDDVNRVQEVSKTAGGKGLNVTRVLAQVGEPVLASGFIG
CEEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCCCC
GELGQFIAKKLDHADIKHAFYNIKGETRNCIAILHEGQQTEILEQGPEIDNQEAAGFIKH
HHHHHHHHHHHCHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHCCCCCCCHHHHHHHHH
FEQLLEKVEAVAISGSLPKGLNQDYYAQIIERCQNKGVPVILDCSGATLQTVLENPYKPT
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCCC
VIKPNISELYQLLNQPLDESLESLKQAVSQPLFEGIEWIIVSLGAQGAFAKHNHTFYRVN
EECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEEE
IPTINVLNPVGSGDSTVAGITSAILNHENDHDLLKKANTLGMLNAQEAQTGYVNLNNYDE
CCEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCHHH
LFNQIEVLEV
HHHHHHHHCC
>Mature Secondary Structure
MILTLTLNPSVDISYPLTALKLDDVNRVQEVSKTAGGKGLNVTRVLAQVGEPVLASGFIG
CEEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCCCC
GELGQFIAKKLDHADIKHAFYNIKGETRNCIAILHEGQQTEILEQGPEIDNQEAAGFIKH
HHHHHHHHHHHCHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHCCCCCCCHHHHHHHHH
FEQLLEKVEAVAISGSLPKGLNQDYYAQIIERCQNKGVPVILDCSGATLQTVLENPYKPT
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCCC
VIKPNISELYQLLNQPLDESLESLKQAVSQPLFEGIEWIIVSLGAQGAFAKHNHTFYRVN
EECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEEE
IPTINVLNPVGSGDSTVAGITSAILNHENDHDLLKKANTLGMLNAQEAQTGYVNLNNYDE
CCEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCHHH
LFNQIEVLEV
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA