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The map label for this gene is argS

Identifier: 15921521

GI number: 15921521

Start: 1255757

End: 1257628

Strand: Direct

Name: argS

Synonym: ST1258

Alternate gene names: 15921521

Gene position: 1255757-1257628 (Clockwise)

Preceding gene: 15921518

Following gene: 15921522

Centisome position: 46.6

GC content: 30.02

Gene sequence:

>1872_bases
GTGAATCCTATAAAAGAAGTGAAGCTCGAATTTGCTAAAATTTTATCGGAAAGGCTAAGCATTGATCAAAACAAAATATA
TGAGAATTTTGAGTACCCTCCAAAAGAACAAATGGGGGACGTTTCACTGCCATTACCAACAGTTACTAAGAATAAAGAAT
TGCTTAATATCTCTGATTTTCCCTCTGGTGGAAAACTTATAAGAGAGATTAAAAAAGCTGGTATATACATTAATGGTGTC
ATAAACGAATCTGAGCTCTTTAAACTTATTTTTACTAATTTTCCCGAGGATTATGGTATTGAAAAAATACAAAAACCCCA
AAGGGTAGTGGTAGAGCATACCAGTGCCAATCCTATTCATCCCTTACATGTGGGTCATTTGAGAAATGCAATATTAGGTG
ATGTAATAGCTAGAATGCTAAAAGCTAGAGGGCATGAAGTTAATACAAGGTTTTATGTTAATGATGCTGGGAGGCAAGTT
GCAATCCTTACTTTAGGTTATCTTTTATTAGGGGAACCAAACCCACCTAGAGATGAGAAAATAGATCAATGGATAGGTGT
TATTTATGCTATAACTAACATTCTAATTGAGATAAATCAATTAAAGAAAGAACTTTCTAGTTCTAATGAAGAGGAATATA
GACAAAAAATATCTAAATTAGACGAATTAATTTCACTTGCAGGCAAACATAGAGAAAAATATCCAGAAATATTTGATAAA
CTTGCTGATGAGATAAGTAAGATAGAAAATATAGAAGAAAAAATACAAAACATAATAAAAAATTATGAGAGACATAGTGA
TGAGAAAATTGTGAATGTAATTAGAAAATTAGTAAACTGGACATTAGAAGGTTTTAAAGACAGTTTAAAGATATTAGATA
TTCATTTTGATAATTTTGATTATGAAAGTGATTTATTATGGAGTAAGAGAGTAGATGAGATTGTAAAATTAGCTCTTTCT
TCAAAAAATATAAAGGAGCATAAAGGTACTATAGCCCTCTCACTTGATTTAGATCCAGAGGCAAGGAAAAGACTTAATAT
TCCATTAGGGTTAGAACTTCCTCCCCTTGTTTTAGTTAGATCTGATGGAACAACTCTTTATACTACTAGAGATATAGCTT
ATTCTTTATATAAATTTGAAGTTTTCTATGCAAATAAAGTAATAAATGTTATAGCTGAACAGCAATCAGTTCCACAAATG
CAATTAAGAGCATCATTATATCTTTTAGGTTTCAAAGATATAGCAGAGAATCTTATACACTATTCTTATGGTATGGTGAA
TTTACAAGGAATGAGAATGAGTGGCAGACTAGGTAGGTATATTTCTTTAGATGAAATAATAAATGAGGTAAAAGAAGTTG
CTGAAAATAAAATAAAAGAAAAAGGAGGAGACTTAAATAATTTGCTAGATATTGTTAACTCAGCTATTAGATATGCTATT
CTGTCAGTATCAGCAAATAAGCCTGTTTCTTTTAACATAAAGAATATAGTTGATTTTGATCAAAATAGTGGACCTTATTT
ACAATATACCTATGCTAGAGCATATAATATATTGGCTAAAAATGAAGAAAAATTAGATATTAATAAAGTAGATTTTAGTG
ATATAGTAGATGATAAGAGGCGTCTTTTAATATCAATCGCAAAATTCCCAGAAGTAGCTACTAAAGCTGTTGATGAATTA
AGACCAGAAGATTTGTTAGGATTTATGAGGAGTATAGCAGATATATTTAACAGATGGTATAACTTTGAAAGAGTTTTACA
AGAACCAAACGAAGGAAAAAGAATGCTAAGACTATTTATAGTTAAAGGTGTCGAAAGAATTCTATATAACGGTCTTAGTA
TTGTTGGAATAAAACCGTTAAAGAGGATGTAA

Upstream 100 bases:

>100_bases
TTTCTCCTCTTAAATCTTCTACTATTAATACCTCGGCTCTTTTCATGTTTTATGACTTAAGAGAGGAAAAAGATATAAAG
ATAGTGGCTTATGCTCTGTT

Downstream 100 bases:

>100_bases
AATAGCGGACCCGCCGGGACTTGAACCCGGGACCGCCGGCTCCCTACTTTAAAACCGCAGGCCGGCGCTCTATCCTGGCT
GAGCTACGGGTCCATGTATA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MNPIKEVKLEFAKILSERLSIDQNKIYENFEYPPKEQMGDVSLPLPTVTKNKELLNISDFPSGGKLIREIKKAGIYINGV
INESELFKLIFTNFPEDYGIEKIQKPQRVVVEHTSANPIHPLHVGHLRNAILGDVIARMLKARGHEVNTRFYVNDAGRQV
AILTLGYLLLGEPNPPRDEKIDQWIGVIYAITNILIEINQLKKELSSSNEEEYRQKISKLDELISLAGKHREKYPEIFDK
LADEISKIENIEEKIQNIIKNYERHSDEKIVNVIRKLVNWTLEGFKDSLKILDIHFDNFDYESDLLWSKRVDEIVKLALS
SKNIKEHKGTIALSLDLDPEARKRLNIPLGLELPPLVLVRSDGTTLYTTRDIAYSLYKFEVFYANKVINVIAEQQSVPQM
QLRASLYLLGFKDIAENLIHYSYGMVNLQGMRMSGRLGRYISLDEIINEVKEVAENKIKEKGGDLNNLLDIVNSAIRYAI
LSVSANKPVSFNIKNIVDFDQNSGPYLQYTYARAYNILAKNEEKLDINKVDFSDIVDDKRRLLISIAKFPEVATKAVDEL
RPEDLLGFMRSIADIFNRWYNFERVLQEPNEGKRMLRLFIVKGVERILYNGLSIVGIKPLKRM

Sequences:

>Translated_623_residues
MNPIKEVKLEFAKILSERLSIDQNKIYENFEYPPKEQMGDVSLPLPTVTKNKELLNISDFPSGGKLIREIKKAGIYINGV
INESELFKLIFTNFPEDYGIEKIQKPQRVVVEHTSANPIHPLHVGHLRNAILGDVIARMLKARGHEVNTRFYVNDAGRQV
AILTLGYLLLGEPNPPRDEKIDQWIGVIYAITNILIEINQLKKELSSSNEEEYRQKISKLDELISLAGKHREKYPEIFDK
LADEISKIENIEEKIQNIIKNYERHSDEKIVNVIRKLVNWTLEGFKDSLKILDIHFDNFDYESDLLWSKRVDEIVKLALS
SKNIKEHKGTIALSLDLDPEARKRLNIPLGLELPPLVLVRSDGTTLYTTRDIAYSLYKFEVFYANKVINVIAEQQSVPQM
QLRASLYLLGFKDIAENLIHYSYGMVNLQGMRMSGRLGRYISLDEIINEVKEVAENKIKEKGGDLNNLLDIVNSAIRYAI
LSVSANKPVSFNIKNIVDFDQNSGPYLQYTYARAYNILAKNEEKLDINKVDFSDIVDDKRRLLISIAKFPEVATKAVDEL
RPEDLLGFMRSIADIFNRWYNFERVLQEPNEGKRMLRLFIVKGVERILYNGLSIVGIKPLKRM
>Mature_623_residues
MNPIKEVKLEFAKILSERLSIDQNKIYENFEYPPKEQMGDVSLPLPTVTKNKELLNISDFPSGGKLIREIKKAGIYINGV
INESELFKLIFTNFPEDYGIEKIQKPQRVVVEHTSANPIHPLHVGHLRNAILGDVIARMLKARGHEVNTRFYVNDAGRQV
AILTLGYLLLGEPNPPRDEKIDQWIGVIYAITNILIEINQLKKELSSSNEEEYRQKISKLDELISLAGKHREKYPEIFDK
LADEISKIENIEEKIQNIIKNYERHSDEKIVNVIRKLVNWTLEGFKDSLKILDIHFDNFDYESDLLWSKRVDEIVKLALS
SKNIKEHKGTIALSLDLDPEARKRLNIPLGLELPPLVLVRSDGTTLYTTRDIAYSLYKFEVFYANKVINVIAEQQSVPQM
QLRASLYLLGFKDIAENLIHYSYGMVNLQGMRMSGRLGRYISLDEIINEVKEVAENKIKEKGGDLNNLLDIVNSAIRYAI
LSVSANKPVSFNIKNIVDFDQNSGPYLQYTYARAYNILAKNEEKLDINKVDFSDIVDDKRRLLISIAKFPEVATKAVDEL
RPEDLLGFMRSIADIFNRWYNFERVLQEPNEGKRMLRLFIVKGVERILYNGLSIVGIKPLKRM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=586, Percent_Identity=24.4027303754266, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI15149476, Length=537, Percent_Identity=23.8361266294227, Blast_Score=107, Evalue=4e-23,
Organism=Escherichia coli, GI1788184, Length=528, Percent_Identity=25, Blast_Score=141, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17532153, Length=535, Percent_Identity=22.2429906542056, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71985061, Length=307, Percent_Identity=23.7785016286645, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6320548, Length=632, Percent_Identity=25, Blast_Score=167, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6321883, Length=643, Percent_Identity=24.8833592534992, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28571570, Length=584, Percent_Identity=21.7465753424658, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_SULTO (Q971X1)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_377190.1
- ProteinModelPortal:   Q971X1
- SMR:   Q971X1
- GeneID:   1459256
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST1258
- NMPDR:   fig|273063.1.peg.1358
- HOGENOM:   HBG695395
- OMA:   NDMGRQI
- ProtClustDB:   PRK01611
- BioCyc:   STOK273063:ST1258-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 71694; Mature: 71694

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPIKEVKLEFAKILSERLSIDQNKIYENFEYPPKEQMGDVSLPLPTVTKNKELLNISDF
CCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCEEEECCC
PSGGKLIREIKKAGIYINGVINESELFKLIFTNFPEDYGIEKIQKPQRVVVEHTSANPIH
CCHHHHHHHHHHCCEEEEEEECHHHHHHHHHHCCCCCCCHHHHCCCHHEEEEECCCCCCC
PLHVGHLRNAILGDVIARMLKARGHEVNTRFYVNDAGRQVAILTLGYLLLGEPNPPRDEK
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHHHHHCCCCCCCCHHH
IDQWIGVIYAITNILIEINQLKKELSSSNEEEYRQKISKLDELISLAGKHREKYPEIFDK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LADEISKIENIEEKIQNIIKNYERHSDEKIVNVIRKLVNWTLEGFKDSLKILDIHFDNFD
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCC
YESDLLWSKRVDEIVKLALSSKNIKEHKGTIALSLDLDPEARKRLNIPLGLELPPLVLVR
CCHHHHHHHHHHHHHHHHHCCCCHHHCCCEEEEEECCCHHHHHHCCCCCCCCCCCEEEEE
SDGTTLYTTRDIAYSLYKFEVFYANKVINVIAEQQSVPQMQLRASLYLLGFKDIAENLIH
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEHHHHHHHHHH
YSYGMVNLQGMRMSGRLGRYISLDEIINEVKEVAENKIKEKGGDLNNLLDIVNSAIRYAI
HHCCCEEEECEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LSVSANKPVSFNIKNIVDFDQNSGPYLQYTYARAYNILAKNEEKLDINKVDFSDIVDDKR
HEECCCCCEEEEHHHHEECCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
RLLISIAKFPEVATKAVDELRPEDLLGFMRSIADIFNRWYNFERVLQEPNEGKRMLRLFI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VKGVERILYNGLSIVGIKPLKRM
HHHHHHHHHCCCCEEECCHHCCC
>Mature Secondary Structure
MNPIKEVKLEFAKILSERLSIDQNKIYENFEYPPKEQMGDVSLPLPTVTKNKELLNISDF
CCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCEEEECCC
PSGGKLIREIKKAGIYINGVINESELFKLIFTNFPEDYGIEKIQKPQRVVVEHTSANPIH
CCHHHHHHHHHHCCEEEEEEECHHHHHHHHHHCCCCCCCHHHHCCCHHEEEEECCCCCCC
PLHVGHLRNAILGDVIARMLKARGHEVNTRFYVNDAGRQVAILTLGYLLLGEPNPPRDEK
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHHHHHCCCCCCCCHHH
IDQWIGVIYAITNILIEINQLKKELSSSNEEEYRQKISKLDELISLAGKHREKYPEIFDK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LADEISKIENIEEKIQNIIKNYERHSDEKIVNVIRKLVNWTLEGFKDSLKILDIHFDNFD
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCC
YESDLLWSKRVDEIVKLALSSKNIKEHKGTIALSLDLDPEARKRLNIPLGLELPPLVLVR
CCHHHHHHHHHHHHHHHHHCCCCHHHCCCEEEEEECCCHHHHHHCCCCCCCCCCCEEEEE
SDGTTLYTTRDIAYSLYKFEVFYANKVINVIAEQQSVPQMQLRASLYLLGFKDIAENLIH
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEHHHHHHHHHH
YSYGMVNLQGMRMSGRLGRYISLDEIINEVKEVAENKIKEKGGDLNNLLDIVNSAIRYAI
HHCCCEEEECEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LSVSANKPVSFNIKNIVDFDQNSGPYLQYTYARAYNILAKNEEKLDINKVDFSDIVDDKR
HEECCCCCEEEEHHHHEECCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
RLLISIAKFPEVATKAVDELRPEDLLGFMRSIADIFNRWYNFERVLQEPNEGKRMLRLFI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VKGVERILYNGLSIVGIKPLKRM
HHHHHHHHHCCCCEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479