Click here to switch to the map view.

The map label for this gene is adh [H]

Identifier: 15920230

GI number: 15920230

Start: 69875

End: 70909

Strand: Reverse

Name: adh [H]

Synonym: ST0053

Alternate gene names: 15920230

Gene position: 70909-69875 (Counterclockwise)

Preceding gene: 15920231

Following gene: 15920229

Centisome position: 2.63

GC content: 34.4

Gene sequence:

>1035_bases
ATGAAAGCTATGTTGATTAAGGAATTTGGAAAGCCGTTAAAATTAGAAGATGTTGATGTTCCTAAGCTTAAGCAAAATCA
AGTTCTCATTAGAGTAAGAAGTGCGGGCGTATGTCATACTGATGTATCAGTAAGAAGTGGTACAATATATAAGAGAGTAT
CTGTAAATCCGCCTAAACTACCCTTTATTCCTGGACATGAAATAGCAGGAATAATAGAAGATGTTGGAGATGAGGTTATA
GGATTTACAAAAGGAGATAAGGTTATAGTAAATCCTTGGCAAGGAGAGGGGAATTGCTACTACTGTAAGATAGGAGAAGA
ACAATATTGTGATTTTCCTACATGGTTAGGAATAAGTACTAATGGTGGTTATGCTGAATATGTAGTTTCTAACTTTAACT
ATGTATATAAAGTAAATAAGTTATCAGTAGAGGAGGCTTCACCTTTAGCTTGTGCGGGAGTTACGGCTTATAGGGCTGCT
AGACTAGCCAATTTAACTCCATCTAAATATGTTATGGTTATAGGTGCGGGAGGCGGATTAGGAAGTTTCGGAGTTCAAAT
AGTTAAAGCATTATATGGTTCTACTGTGATAGCAGTAGACATCAATGAAGAGGGATTAAAATTAGCGTCAAGATTAGGAT
CTGACTATGTCATGAATGCTAAAGATCAAAGTTTACTTCAAGAAATATTGAGGATAACTGAGGGAAGAGGAGTTGATGCA
ATATTAGACTTTGTGGGATCTGAGAGTACTACAAAAAACTATTATACAATATTAGCAAAATTAGGTAGATACATTAAAGT
TGGTACTTTTGGTGGAGGTTTGCCACAAGAAGCTGGGTTAAAGTTACACTCAATGGGTTGGGAATTTATTGGTACTCTAA
CTGGTAATAGAAGAGATTTTCTAGAAATTATAAAATTGGCTGAAAGTGGAAAGATAAGAATTGTTATAACCAAATTATCG
TTAGAAGAAGCTAATGAAGCTTTAAATAATTTAGAATCTAATAAAGTAACGGGAAGGCAAGTATTAATACCTTAA

Upstream 100 bases:

>100_bases
TAGTGATTGTAGGGGTAATCCTATTAATATCCTCAATTATAACTAATGATACAAAGGGTAATATTTTAAAGGAAATTGAA
TCAGTTGAAAAGGGAGCTAT

Downstream 100 bases:

>100_bases
ATATGGTAGAGTAGAATATGGAAATTAGAAAGTTTATTGAAGAGGTTAGAAGATTAAACCTTTTGAGGGAGATTAAGGGA
GCAAACTGGAATTTAGAAAT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKAMLIKEFGKPLKLEDVDVPKLKQNQVLIRVRSAGVCHTDVSVRSGTIYKRVSVNPPKLPFIPGHEIAGIIEDVGDEVI
GFTKGDKVIVNPWQGEGNCYYCKIGEEQYCDFPTWLGISTNGGYAEYVVSNFNYVYKVNKLSVEEASPLACAGVTAYRAA
RLANLTPSKYVMVIGAGGGLGSFGVQIVKALYGSTVIAVDINEEGLKLASRLGSDYVMNAKDQSLLQEILRITEGRGVDA
ILDFVGSESTTKNYYTILAKLGRYIKVGTFGGGLPQEAGLKLHSMGWEFIGTLTGNRRDFLEIIKLAESGKIRIVITKLS
LEEANEALNNLESNKVTGRQVLIP

Sequences:

>Translated_344_residues
MKAMLIKEFGKPLKLEDVDVPKLKQNQVLIRVRSAGVCHTDVSVRSGTIYKRVSVNPPKLPFIPGHEIAGIIEDVGDEVI
GFTKGDKVIVNPWQGEGNCYYCKIGEEQYCDFPTWLGISTNGGYAEYVVSNFNYVYKVNKLSVEEASPLACAGVTAYRAA
RLANLTPSKYVMVIGAGGGLGSFGVQIVKALYGSTVIAVDINEEGLKLASRLGSDYVMNAKDQSLLQEILRITEGRGVDA
ILDFVGSESTTKNYYTILAKLGRYIKVGTFGGGLPQEAGLKLHSMGWEFIGTLTGNRRDFLEIIKLAESGKIRIVITKLS
LEEANEALNNLESNKVTGRQVLIP
>Mature_344_residues
MKAMLIKEFGKPLKLEDVDVPKLKQNQVLIRVRSAGVCHTDVSVRSGTIYKRVSVNPPKLPFIPGHEIAGIIEDVGDEVI
GFTKGDKVIVNPWQGEGNCYYCKIGEEQYCDFPTWLGISTNGGYAEYVVSNFNYVYKVNKLSVEEASPLACAGVTAYRAA
RLANLTPSKYVMVIGAGGGLGSFGVQIVKALYGSTVIAVDINEEGLKLASRLGSDYVMNAKDQSLLQEILRITEGRGVDA
ILDFVGSESTTKNYYTILAKLGRYIKVGTFGGGLPQEAGLKLHSMGWEFIGTLTGNRRDFLEIIKLAESGKIRIVITKLS
LEEANEALNNLESNKVTGRQVLIP

Specific function: Preferred Specificity Is Towards 1-Propanol. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=276, Percent_Identity=32.2463768115942, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI13236495, Length=276, Percent_Identity=32.2463768115942, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI4501929, Length=372, Percent_Identity=29.8387096774194, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI34577061, Length=372, Percent_Identity=30.3763440860215, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI4501933, Length=372, Percent_Identity=29.3010752688172, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI194239676, Length=257, Percent_Identity=32.6848249027237, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI24308257, Length=277, Percent_Identity=30.3249097472924, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI71565154, Length=371, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI156627571, Length=250, Percent_Identity=28.4, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI156523966, Length=375, Percent_Identity=27.7333333333333, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI4501939, Length=367, Percent_Identity=27.7929155313352, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI71743840, Length=273, Percent_Identity=26.007326007326, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI262073058, Length=273, Percent_Identity=26.007326007326, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI47519420, Length=383, Percent_Identity=25.3263707571802, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI22538446, Length=277, Percent_Identity=24.9097472924188, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI22538444, Length=277, Percent_Identity=24.9097472924188, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI87081918, Length=326, Percent_Identity=30.0613496932515, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1788073, Length=267, Percent_Identity=29.5880149812734, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI87082125, Length=283, Percent_Identity=30.7420494699647, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786518, Length=362, Percent_Identity=28.7292817679558, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787863, Length=270, Percent_Identity=28.5185185185185, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790045, Length=269, Percent_Identity=26.3940520446097, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI226510992, Length=312, Percent_Identity=25.3205128205128, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788407, Length=351, Percent_Identity=27.3504273504274, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI87082401, Length=347, Percent_Identity=24.207492795389, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788075, Length=355, Percent_Identity=23.3802816901408, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786552, Length=362, Percent_Identity=26.5193370165746, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790718, Length=317, Percent_Identity=24.2902208201893, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994910, Length=366, Percent_Identity=24.5901639344262, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562584, Length=349, Percent_Identity=29.7994269340974, Blast_Score=137, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71988145, Length=348, Percent_Identity=26.7241379310345, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17562582, Length=351, Percent_Identity=27.9202279202279, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17562876, Length=266, Percent_Identity=28.9473684210526, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17562878, Length=210, Percent_Identity=31.9047619047619, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17507255, Length=272, Percent_Identity=28.6764705882353, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25146526, Length=271, Percent_Identity=26.1992619926199, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323961, Length=344, Percent_Identity=28.4883720930233, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6319621, Length=344, Percent_Identity=27.6162790697674, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6324486, Length=344, Percent_Identity=27.906976744186, Blast_Score=138, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6323729, Length=349, Percent_Identity=29.2263610315186, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320033, Length=365, Percent_Identity=27.3972602739726, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319520, Length=360, Percent_Identity=26.3888888888889, Blast_Score=92, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6319257, Length=318, Percent_Identity=25.7861635220126, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323099, Length=354, Percent_Identity=22.5988700564972, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319258, Length=298, Percent_Identity=23.1543624161074, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322619, Length=342, Percent_Identity=23.0994152046784, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319955, Length=342, Percent_Identity=23.0994152046784, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17737895, Length=368, Percent_Identity=28.2608695652174, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17137530, Length=247, Percent_Identity=25.1012145748988, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17737897, Length=245, Percent_Identity=25.7142857142857, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 37478; Mature: 37478

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAMLIKEFGKPLKLEDVDVPKLKQNQVLIRVRSAGVCHTDVSVRSGTIYKRVSVNPPKL
CCCEEEHHCCCCCEECCCCCCCCCCCEEEEEEECCCEEEECCEECCCEEEEEEECCCCCC
PFIPGHEIAGIIEDVGDEVIGFTKGDKVIVNPWQGEGNCYYCKIGEEQYCDFPTWLGIST
CCCCCHHHHHHHHHCCCHHEEECCCCEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEC
NGGYAEYVVSNFNYVYKVNKLSVEEASPLACAGVTAYRAARLANLTPSKYVMVIGAGGGL
CCCEEEEEEECCEEEEEEEEEECCCCCCCEEHHHHHHHHHHHCCCCCCCEEEEEECCCCC
GSFGVQIVKALYGSTVIAVDINEEGLKLASRLGSDYVMNAKDQSLLQEILRITEGRGVDA
HHHHHHHHHHHHCCEEEEEEECHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHCCCCHHH
ILDFVGSESTTKNYYTILAKLGRYIKVGTFGGGLPQEAGLKLHSMGWEFIGTLTGNRRDF
HHHHHCCCCCCHHHHHHHHHHCCEEEEECCCCCCCHHHCCEEECCCCEEEEEECCCHHHH
LEIIKLAESGKIRIVITKLSLEEANEALNNLESNKVTGRQVLIP
HHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCEEECC
>Mature Secondary Structure
MKAMLIKEFGKPLKLEDVDVPKLKQNQVLIRVRSAGVCHTDVSVRSGTIYKRVSVNPPKL
CCCEEEHHCCCCCEECCCCCCCCCCCEEEEEEECCCEEEECCEECCCEEEEEEECCCCCC
PFIPGHEIAGIIEDVGDEVIGFTKGDKVIVNPWQGEGNCYYCKIGEEQYCDFPTWLGIST
CCCCCHHHHHHHHHCCCHHEEECCCCEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEC
NGGYAEYVVSNFNYVYKVNKLSVEEASPLACAGVTAYRAARLANLTPSKYVMVIGAGGGL
CCCEEEEEEECCEEEEEEEEEECCCCCCCEEHHHHHHHHHHHCCCCCCCEEEEEECCCCC
GSFGVQIVKALYGSTVIAVDINEEGLKLASRLGSDYVMNAKDQSLLQEILRITEGRGVDA
HHHHHHHHHHHHCCEEEEEEECHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHCCCCHHH
ILDFVGSESTTKNYYTILAKLGRYIKVGTFGGGLPQEAGLKLHSMGWEFIGTLTGNRRDF
HHHHHCCCCCCHHHHHHHHHHCCEEEEECCCCCCCHHHCCEEECCCCEEEEEECCCHHHH
LEIIKLAESGKIRIVITKLSLEEANEALNNLESNKVTGRQVLIP
HHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA