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The map label for this gene is coxL [H]

Identifier: 15920224

GI number: 15920224

Start: 62961

End: 64643

Strand: Reverse

Name: coxL [H]

Synonym: ST0047

Alternate gene names: 15920224

Gene position: 64643-62961 (Counterclockwise)

Preceding gene: 15920225

Following gene: 15920223

Centisome position: 2.4

GC content: 34.34

Gene sequence:

>1683_bases
ATGATATTTAAAGAGGGGTTTCGATTTGTAAAGGGAGAAGGTTCGTATATTGATGACGTATTAACTAAAGAAATAAAAGG
TTATTTTTCTGTTTCTATAGTTAGATCTCCTTATGCTCATGCAAAAATAATAAGAATCAACAAAGATGATGCAGAGAAAT
TAAACGGGGTAGTAAAAGTAATAACATATAACGATTTAAGGAATTTTTTAGACCCCTTTCCACTATCACTTGACATAAAT
TTAGAATATTATCCGATAGCTAGAGATAAAACAATGTATTATGGTGAACCGGTTGCAGTAATAGTAGCAAAAGATGATTA
CATAGCAGAAGATGCAAAAGAACTAGTGCAAGTAGATTACGAACCATTGGATGCAGTTGTAAGTATATCTGATGCAATTT
CCAAGCCACCAATTCATCCTAATCTAAAATCAAATATAGTACTAGATAAAACTTTTATTTACGGAAAATATATGGACGAA
ATTAAGAAAGCAAATATAATAGTTGAGGAAAAGATAAAATTTCCAAGATATACTGCATCTCCGCTGGAAACATATGAAGT
TTATGCCAAATATAACGGAGAAGAGTACGAGATTTTTTCTAATTTTCAAGGACCATTTACCATTCATTATCTCTTAAGTA
AAGCATTAAAATCTAAATTAGTTATAAGAGGACCAAGAGACATAGGAGGATCATTTGGCATTAAGAGCGCAATTTATCCA
TACATGGCTTTAATTGCAGCATCTTCAAGACTAGTAAACAGACCATTAAAATGGATAGAAACTAGAAACGAACACTTAAC
TTCAAGTTCCGTTGGAGCTGAAAGAGAATCGATTATAAGAATATATGGAGATAAGGAGGGAAAAATCCACGCTATAGACA
TGGAACTCACAGATAACTTAGGAGCATATCCTAGACCTCCAGAGCCCGGAAATTTGCTTAGAAACCACGGAAATTTAACT
GGTCCTTATGATGTACAAGCATTAAAATTAACGTATAGAGCAGTCCTAACTAACACAGTACCCACTGGGTTAAATAGGGG
TTATGGAGGACCGCATTTGTATTTAGCATTAGAGAGTGCAATAGATGAATTTGCAAGAGAAATAGGTATGGATCCCATGG
AGGTTAGGATAAAAAATGTGATAAAAACTACACAATACGAGACAGTTACTGGAGGCAAATACTACGGATTCAGCTGTTAT
AATGTAGTAAAAAGGATGAAAGAGTTGTACGATAAGCTTAAGGTAGAGGTTAATGAGGAAAGAAAAAGAGGAAAGAGGGT
TGCAATAGGTACCTCACTAGTAGTAGAGCCATCCGGTACTAATATAGGATATTTAGACTTAGCTAGAGAAAGTAAGGACT
ATTTACCTAAATCTTCAGCTCAAGATATGGTAATTGTGCAAATAGATCCATATTCGAAAGTTAAAGTAATAGTGAATGGG
ACTAATGAGGGACAAGGTCATGAGACTGTAATCTCCGAAATAGTGTCCAAAAGATTAGGAGTAAACCCAGAGGATGTAGA
TGTAATATACAGTGTTGATACAAATAGACCATGGGTTATATCCTCTGGCAGTTATTCCAGTAGATTTACTCCGATAGTTT
TACCAGCACTAAATAATGCATTAGACCAATTAGAGAATAGGGACTGTTCTCAAACAGTCATCAAATTCGATAAGTGTTTG
TAA

Upstream 100 bases:

>100_bases
AAAGGAAAACTTTCGGCTTACTTAGATATAGTGAAGACTTCAGAGAAGGCGTAGAGTCCTTCTTAAATAAGAGGAAGCCT
AATTTTAACGGTAGGTAAGT

Downstream 100 bases:

>100_bases
AAATATTATGATGTTCATAAAAATAGTTTTTTCTAATGTGACTCACTAAGAAGAGCTAGAAGTGTAAAGAGTAAAAATTG
TTTTAGAAAAATTTATGTGC

Product: dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MIFKEGFRFVKGEGSYIDDVLTKEIKGYFSVSIVRSPYAHAKIIRINKDDAEKLNGVVKVITYNDLRNFLDPFPLSLDIN
LEYYPIARDKTMYYGEPVAVIVAKDDYIAEDAKELVQVDYEPLDAVVSISDAISKPPIHPNLKSNIVLDKTFIYGKYMDE
IKKANIIVEEKIKFPRYTASPLETYEVYAKYNGEEYEIFSNFQGPFTIHYLLSKALKSKLVIRGPRDIGGSFGIKSAIYP
YMALIAASSRLVNRPLKWIETRNEHLTSSSVGAERESIIRIYGDKEGKIHAIDMELTDNLGAYPRPPEPGNLLRNHGNLT
GPYDVQALKLTYRAVLTNTVPTGLNRGYGGPHLYLALESAIDEFAREIGMDPMEVRIKNVIKTTQYETVTGGKYYGFSCY
NVVKRMKELYDKLKVEVNEERKRGKRVAIGTSLVVEPSGTNIGYLDLARESKDYLPKSSAQDMVIVQIDPYSKVKVIVNG
TNEGQGHETVISEIVSKRLGVNPEDVDVIYSVDTNRPWVISSGSYSSRFTPIVLPALNNALDQLENRDCSQTVIKFDKCL

Sequences:

>Translated_560_residues
MIFKEGFRFVKGEGSYIDDVLTKEIKGYFSVSIVRSPYAHAKIIRINKDDAEKLNGVVKVITYNDLRNFLDPFPLSLDIN
LEYYPIARDKTMYYGEPVAVIVAKDDYIAEDAKELVQVDYEPLDAVVSISDAISKPPIHPNLKSNIVLDKTFIYGKYMDE
IKKANIIVEEKIKFPRYTASPLETYEVYAKYNGEEYEIFSNFQGPFTIHYLLSKALKSKLVIRGPRDIGGSFGIKSAIYP
YMALIAASSRLVNRPLKWIETRNEHLTSSSVGAERESIIRIYGDKEGKIHAIDMELTDNLGAYPRPPEPGNLLRNHGNLT
GPYDVQALKLTYRAVLTNTVPTGLNRGYGGPHLYLALESAIDEFAREIGMDPMEVRIKNVIKTTQYETVTGGKYYGFSCY
NVVKRMKELYDKLKVEVNEERKRGKRVAIGTSLVVEPSGTNIGYLDLARESKDYLPKSSAQDMVIVQIDPYSKVKVIVNG
TNEGQGHETVISEIVSKRLGVNPEDVDVIYSVDTNRPWVISSGSYSSRFTPIVLPALNNALDQLENRDCSQTVIKFDKCL
>Mature_560_residues
MIFKEGFRFVKGEGSYIDDVLTKEIKGYFSVSIVRSPYAHAKIIRINKDDAEKLNGVVKVITYNDLRNFLDPFPLSLDIN
LEYYPIARDKTMYYGEPVAVIVAKDDYIAEDAKELVQVDYEPLDAVVSISDAISKPPIHPNLKSNIVLDKTFIYGKYMDE
IKKANIIVEEKIKFPRYTASPLETYEVYAKYNGEEYEIFSNFQGPFTIHYLLSKALKSKLVIRGPRDIGGSFGIKSAIYP
YMALIAASSRLVNRPLKWIETRNEHLTSSSVGAERESIIRIYGDKEGKIHAIDMELTDNLGAYPRPPEPGNLLRNHGNLT
GPYDVQALKLTYRAVLTNTVPTGLNRGYGGPHLYLALESAIDEFAREIGMDPMEVRIKNVIKTTQYETVTGGKYYGFSCY
NVVKRMKELYDKLKVEVNEERKRGKRVAIGTSLVVEPSGTNIGYLDLARESKDYLPKSSAQDMVIVQIDPYSKVKVIVNG
TNEGQGHETVISEIVSKRLGVNPEDVDVIYSVDTNRPWVISSGSYSSRFTPIVLPALNNALDQLENRDCSQTVIKFDKCL

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=569, Percent_Identity=24.6045694200351, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI91823271, Length=503, Percent_Identity=25.2485089463221, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1789230, Length=569, Percent_Identity=23.725834797891, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI1789246, Length=583, Percent_Identity=22.8130360205832, Blast_Score=115, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=529, Percent_Identity=24.3856332703214, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17539860, Length=517, Percent_Identity=22.0502901353965, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17737937, Length=518, Percent_Identity=24.1312741312741, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 63109; Mature: 63109

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFKEGFRFVKGEGSYIDDVLTKEIKGYFSVSIVRSPYAHAKIIRINKDDAEKLNGVVKV
CCCCCCCEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCHHHHCCCEEEE
ITYNDLRNFLDPFPLSLDINLEYYPIARDKTMYYGEPVAVIVAKDDYIAEDAKELVQVDY
EEHHHHHHHHCCCCCEEEEEEEEEECCCCCEEEECCCEEEEEECCCHHHHHHHHHHHCCC
EPLDAVVSISDAISKPPIHPNLKSNIVLDKTFIYGKYMDEIKKANIIVEEKIKFPRYTAS
CHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHEEHHHHHHHHHHCCEEEEECCCCCCCCCC
PLETYEVYAKYNGEEYEIFSNFQGPFTIHYLLSKALKSKLVIRGPRDIGGSFGIKSAIYP
CCCEEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHCCEEEECCHHCCCCCCHHHHHHH
YMALIAASSRLVNRPLKWIETRNEHLTSSSVGAERESIIRIYGDKEGKIHAIDMELTDNL
HHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCC
GAYPRPPEPGNLLRNHGNLTGPYDVQALKLTYRAVLTNTVPTGLNRGYGGPHLYLALESA
CCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHH
IDEFAREIGMDPMEVRIKNVIKTTQYETVTGGKYYGFSCYNVVKRMKELYDKLKVEVNEE
HHHHHHHHCCCHHHHHHHHHHHHCCEEEECCCCEECCHHHHHHHHHHHHHHHHEEEECHH
RKRGKRVAIGTSLVVEPSGTNIGYLDLARESKDYLPKSSAQDMVIVQIDPYSKVKVIVNG
HHCCCEEEEEEEEEEECCCCCEEEEEECCCCHHCCCCCCCCCEEEEEECCCCEEEEEEEC
TNEGQGHETVISEIVSKRLGVNPEDVDVIYSVDTNRPWVISSGSYSSRFTPIVLPALNNA
CCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEECCCCCCCCCEEEHHHHHHH
LDQLENRDCSQTVIKFDKCL
HHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MIFKEGFRFVKGEGSYIDDVLTKEIKGYFSVSIVRSPYAHAKIIRINKDDAEKLNGVVKV
CCCCCCCEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCHHHHCCCEEEE
ITYNDLRNFLDPFPLSLDINLEYYPIARDKTMYYGEPVAVIVAKDDYIAEDAKELVQVDY
EEHHHHHHHHCCCCCEEEEEEEEEECCCCCEEEECCCEEEEEECCCHHHHHHHHHHHCCC
EPLDAVVSISDAISKPPIHPNLKSNIVLDKTFIYGKYMDEIKKANIIVEEKIKFPRYTAS
CHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHEEHHHHHHHHHHCCEEEEECCCCCCCCCC
PLETYEVYAKYNGEEYEIFSNFQGPFTIHYLLSKALKSKLVIRGPRDIGGSFGIKSAIYP
CCCEEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHCCEEEECCHHCCCCCCHHHHHHH
YMALIAASSRLVNRPLKWIETRNEHLTSSSVGAERESIIRIYGDKEGKIHAIDMELTDNL
HHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCC
GAYPRPPEPGNLLRNHGNLTGPYDVQALKLTYRAVLTNTVPTGLNRGYGGPHLYLALESA
CCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHH
IDEFAREIGMDPMEVRIKNVIKTTQYETVTGGKYYGFSCYNVVKRMKELYDKLKVEVNEE
HHHHHHHHCCCHHHHHHHHHHHHCCEEEECCCCEECCHHHHHHHHHHHHHHHHEEEECHH
RKRGKRVAIGTSLVVEPSGTNIGYLDLARESKDYLPKSSAQDMVIVQIDPYSKVKVIVNG
HHCCCEEEEEEEEEEECCCCCEEEEEECCCCHHCCCCCCCCCEEEEEECCCCEEEEEEEC
TNEGQGHETVISEIVSKRLGVNPEDVDVIYSVDTNRPWVISSGSYSSRFTPIVLPALNNA
CCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEECCCCCCCCCEEEHHHHHHH
LDQLENRDCSQTVIKFDKCL
HHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 12515558; 10430865; 12475995 [H]