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The map label for this gene is yfkJ [H]

Identifier: 159185323

GI number: 159185323

Start: 2660325

End: 2660804

Strand: Direct

Name: yfkJ [H]

Synonym: Atu2677

Alternate gene names: 159185323

Gene position: 2660325-2660804 (Clockwise)

Preceding gene: 159185318

Following gene: 15889935

Centisome position: 93.62

GC content: 58.13

Gene sequence:

>480_bases
ATGAAACATATCACCGTTCTTTTCGTCTGCATGGGCAATATCTGCCGCTCGCCGCTTGCCGAAGGGGTTTTGACTGACCT
TGCCGATGGTGAAGGCGTGTCCGACCGGATCACCGTTGATTCCGCCGGCACCGGCGGCTGGCATACGGGCGACGCACCCG
ATCCGCGATCTATCGCCATGGCGCGGCGACACGGCATCGATATTTCCCGACAACGGGCAAGACAGGTGACGCGGGCTGAT
TTTGAGGCCTTCGACCTCATCCTCGCCATGGACGAAAACAATCTGGCGAACCTGCTTCAACTGAGCCCGGAAAAATACCG
GCACAAAATCCATCTCTTCATGGATTATGCCGCAGGCCACCCGGAGAACGTCCCCGATCCCTATTACGGGGCCGAGGACG
GGTTCCTTGATGTCTACAACATGCTCTTGGCGGGATGCAGATCGTTGCTCGAAAAGATGGAGCTGGACCGCGCCTCGTGA

Upstream 100 bases:

>100_bases
GCCTGCCGGATGGCGTCCGGTTCGAGTCTGGGATATTTCATGAATCTTGCCTCCGTTTGATAACCACTAACGCCTCAACG
ACCGGATCGACGCATCGTTC

Downstream 100 bases:

>100_bases
AGCGGGAAAGCCTCCTCGACGACATACGGCCCGCCGCCCACCGATTCCTTCGACGACATCAGCACGAAACGGCCGACCGT
GAAGGGCGAGGTGCGGAAGT

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MKHITVLFVCMGNICRSPLAEGVLTDLADGEGVSDRITVDSAGTGGWHTGDAPDPRSIAMARRHGIDISRQRARQVTRAD
FEAFDLILAMDENNLANLLQLSPEKYRHKIHLFMDYAAGHPENVPDPYYGAEDGFLDVYNMLLAGCRSLLEKMELDRAS

Sequences:

>Translated_159_residues
MKHITVLFVCMGNICRSPLAEGVLTDLADGEGVSDRITVDSAGTGGWHTGDAPDPRSIAMARRHGIDISRQRARQVTRAD
FEAFDLILAMDENNLANLLQLSPEKYRHKIHLFMDYAAGHPENVPDPYYGAEDGFLDVYNMLLAGCRSLLEKMELDRAS
>Mature_159_residues
MKHITVLFVCMGNICRSPLAEGVLTDLADGEGVSDRITVDSAGTGGWHTGDAPDPRSIAMARRHGIDISRQRARQVTRAD
FEAFDLILAMDENNLANLLQLSPEKYRHKIHLFMDYAAGHPENVPDPYYGAEDGFLDVYNMLLAGCRSLLEKMELDRAS

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=150, Percent_Identity=42, Blast_Score=130, Evalue=3e-31,
Organism=Homo sapiens, GI4757714, Length=150, Percent_Identity=44, Blast_Score=127, Evalue=4e-30,
Organism=Homo sapiens, GI96304457, Length=78, Percent_Identity=47.4358974358974, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788375, Length=141, Percent_Identity=36.1702127659575, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI87081812, Length=142, Percent_Identity=33.8028169014084, Blast_Score=74, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6325330, Length=153, Percent_Identity=32.0261437908497, Blast_Score=107, Evalue=6e-25,
Organism=Drosophila melanogaster, GI78706766, Length=150, Percent_Identity=38, Blast_Score=115, Evalue=9e-27,
Organism=Drosophila melanogaster, GI78706768, Length=150, Percent_Identity=38, Blast_Score=115, Evalue=9e-27,
Organism=Drosophila melanogaster, GI78706764, Length=125, Percent_Identity=40, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI78706770, Length=155, Percent_Identity=36.7741935483871, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI78706772, Length=155, Percent_Identity=36.7741935483871, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI78711846, Length=159, Percent_Identity=35.2201257861635, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648069, Length=99, Percent_Identity=42.4242424242424, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17635; Mature: 17635

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHITVLFVCMGNICRSPLAEGVLTDLADGEGVSDRITVDSAGTGGWHTGDAPDPRSIAM
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHH
ARRHGIDISRQRARQVTRADFEAFDLILAMDENNLANLLQLSPEKYRHKIHLFMDYAAGH
HHHHCCCHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHCCHHHHHHHHHEEEECCCCC
PENVPDPYYGAEDGFLDVYNMLLAGCRSLLEKMELDRAS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKHITVLFVCMGNICRSPLAEGVLTDLADGEGVSDRITVDSAGTGGWHTGDAPDPRSIAM
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHH
ARRHGIDISRQRARQVTRADFEAFDLILAMDENNLANLLQLSPEKYRHKIHLFMDYAAGH
HHHHCCCHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHCCHHHHHHHHHEEEECCCCC
PENVPDPYYGAEDGFLDVYNMLLAGCRSLLEKMELDRAS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]