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The map label for this gene is rhtC [H]

Identifier: 159185302

GI number: 159185302

Start: 2617048

End: 2617662

Strand: Reverse

Name: rhtC [H]

Synonym: Atu2633

Alternate gene names: 159185302

Gene position: 2617662-2617048 (Counterclockwise)

Preceding gene: 159185303

Following gene: 15889887

Centisome position: 92.12

GC content: 57.07

Gene sequence:

>615_bases
ATGGCCATTTTCGCTTTCGCAATCGTATCGCCGGGCGCCGATCTTGCGATGGTCATGCGCCAGGCCATGGTGCATGGACG
CAAGCAGGCCATCATCACAAGCTTCGGCGTCGGAACATCGCTGATGTTCCATGTTACCTATACGATCCTTGGACTTGGCC
TCATAATTTCCCAGTCGATCTATCTCTTCAACATCGTCAAATGGCTCGGTGTCGCCTATCTGATCTATATCGGCATCAAG
GCGCTGCGCGCCGGCAAGACCGAATTGCCGACGGCGGAAGGTGGTGAGGACGGCGTTCGAGCCAAAAGCGACCAGACCGG
GCTCAAGGCCTTCACGCTCGGTTTTGCCGCAAACGCGCTCAATCCCAAACCGGTGTTCTTCTTCCTGTCGATCTTTTCGA
CGGTGGTTCACGCGCATACACCTGTTGGCATCAAGTTCGGATATGGGCTCGTCATGGCAAGCTGCCTTATCCTGTGGTTC
GTCGGCGTCAGCCTGTTCATGACGACGCCGCGCATGCGCGCCGCATTTCAGCGCGCCAGCCAATGGATCGACCGTACCAG
CGGCGTGGTCTTCATCGCACTCGGCATAAAACTCGCAACGGAAAAAGCGGCCTGA

Upstream 100 bases:

>100_bases
TCTGGTTGGGTTCAATGCTTGGACTTGCGCTGATGTTTGTTGTGTTGATGTTCTGAGGTCTGATGTGGTGCACCAATATC
TTATCGAACTGACATCGCTG

Downstream 100 bases:

>100_bases
GTTTCAGGTCAAACGGAAGCAGGGCGGTTCAAATCCTGCCCGATATCAATCAGGAACAGAAATATGGCATATGATGTAGT
TGTAATCGGAACGGGTCCCG

Product: RhtB family transporter

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MAIFAFAIVSPGADLAMVMRQAMVHGRKQAIITSFGVGTSLMFHVTYTILGLGLIISQSIYLFNIVKWLGVAYLIYIGIK
ALRAGKTELPTAEGGEDGVRAKSDQTGLKAFTLGFAANALNPKPVFFFLSIFSTVVHAHTPVGIKFGYGLVMASCLILWF
VGVSLFMTTPRMRAAFQRASQWIDRTSGVVFIALGIKLATEKAA

Sequences:

>Translated_204_residues
MAIFAFAIVSPGADLAMVMRQAMVHGRKQAIITSFGVGTSLMFHVTYTILGLGLIISQSIYLFNIVKWLGVAYLIYIGIK
ALRAGKTELPTAEGGEDGVRAKSDQTGLKAFTLGFAANALNPKPVFFFLSIFSTVVHAHTPVGIKFGYGLVMASCLILWF
VGVSLFMTTPRMRAAFQRASQWIDRTSGVVFIALGIKLATEKAA
>Mature_203_residues
AIFAFAIVSPGADLAMVMRQAMVHGRKQAIITSFGVGTSLMFHVTYTILGLGLIISQSIYLFNIVKWLGVAYLIYIGIKA
LRAGKTELPTAEGGEDGVRAKSDQTGLKAFTLGFAANALNPKPVFFFLSIFSTVVHAHTPVGIKFGYGLVMASCLILWFV
GVSLFMTTPRMRAAFQRASQWIDRTSGVVFIALGIKLATEKAA

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=197, Percent_Identity=29.9492385786802, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1786522, Length=201, Percent_Identity=27.363184079602, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI48994979, Length=133, Percent_Identity=30.0751879699248, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22014; Mature: 21883

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIFAFAIVSPGADLAMVMRQAMVHGRKQAIITSFGVGTSLMFHVTYTILGLGLIISQSI
CEEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YLFNIVKWLGVAYLIYIGIKALRAGKTELPTAEGGEDGVRAKSDQTGLKAFTLGFAANAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
NPKPVFFFLSIFSTVVHAHTPVGIKFGYGLVMASCLILWFVGVSLFMTTPRMRAAFQRAS
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
QWIDRTSGVVFIALGIKLATEKAA
HHHHHCCCEEEEEECCCHHCCCCC
>Mature Secondary Structure 
AIFAFAIVSPGADLAMVMRQAMVHGRKQAIITSFGVGTSLMFHVTYTILGLGLIISQSI
EEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YLFNIVKWLGVAYLIYIGIKALRAGKTELPTAEGGEDGVRAKSDQTGLKAFTLGFAANAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
NPKPVFFFLSIFSTVVHAHTPVGIKFGYGLVMASCLILWFVGVSLFMTTPRMRAAFQRAS
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
QWIDRTSGVVFIALGIKLATEKAA
HHHHHCCCEEEEEECCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]