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The map label for this gene is crp [C]

Identifier: 159185274

GI number: 159185274

Start: 2552801

End: 2553256

Strand: Direct

Name: crp [C]

Synonym: Atu2578

Alternate gene names: 159185274

Gene position: 2552801-2553256 (Clockwise)

Preceding gene: 15889834

Following gene: 159185275

Centisome position: 89.84

GC content: 53.95

Gene sequence:

>456_bases
ATGCTGTTTAAAGACGAAATTCAGATGTTGAAAAGGGTTCCGTTTTTCTCGGAAATGGAACCATCCAAACTCAAGCTGCT
CGCATTCGCATCCGACCGGGTGTCCTATCATGCTGGCGATACACTTTTTCGGCAGGGAGATGTCGGCGATGCGGCCTATG
TTCTCCTGACTGGAAAAGTGGATGTTCTGGTCGATTCCCCATCGGGCACGCTGAAAGTGGCGGAAATGACCGGCAACGCC
ATCGTCGGTGAAATCGCCATTCTCTGTGACAGCGTCAGAACCGCGACCATTCGTGCCTCCACCAATGTGGAAGCCCTGCG
CATCGGCAAGGAACAGTTCTTCAAGCTCATGTCCGATTTCCCCGACATTACCATAAAGGTCATGCGCGTTCTCGCCGAAC
GCCTTACCCAGACGACGGCGGAACTGAGCAAAGCGCGCGCAGGCGCCAAGACATAA

Upstream 100 bases:

>100_bases
AGTTACGAGACTCTCGCCGAGGAAAACGGTACATTCAAGGACATGGTCGCGACATAAATCCAAGAATGTGACCGAGGTGG
AACAAGAACAGGGTAAGGCA

Downstream 100 bases:

>100_bases
ACGACAATTCCTTGCTACCTTGAATGGCGATATTGGAAAAATAAATGTCGTACTATTGCAATATAAATGAAATGCTGACT
GAATAAGGGGTAAAGGGGCC

Product: cAMP-dependent protein kinase regulatory subunit

Products: NA

Alternate protein names: CAMP-Dependent Protein Kinase Regulatory Subunit; Transcriptional Regulator; ABC Transporter Permease Protein; Crp/Fnr Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; Transcriptional Regulator Crp; Catabolite Gene Activator; Transcriptional Regulator Protein; CAMP-Dependent Kinase Protein; Stage II Sporulation Protein E; CAMP-Dependent Protein Kinase

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MLFKDEIQMLKRVPFFSEMEPSKLKLLAFASDRVSYHAGDTLFRQGDVGDAAYVLLTGKVDVLVDSPSGTLKVAEMTGNA
IVGEIAILCDSVRTATIRASTNVEALRIGKEQFFKLMSDFPDITIKVMRVLAERLTQTTAELSKARAGAKT

Sequences:

>Translated_151_residues
MLFKDEIQMLKRVPFFSEMEPSKLKLLAFASDRVSYHAGDTLFRQGDVGDAAYVLLTGKVDVLVDSPSGTLKVAEMTGNA
IVGEIAILCDSVRTATIRASTNVEALRIGKEQFFKLMSDFPDITIKVMRVLAERLTQTTAELSKARAGAKT
>Mature_151_residues
MLFKDEIQMLKRVPFFSEMEPSKLKLLAFASDRVSYHAGDTLFRQGDVGDAAYVLLTGKVDVLVDSPSGTLKVAEMTGNA
IVGEIAILCDSVRTATIRASTNVEALRIGKEQFFKLMSDFPDITIKVMRVLAERLTQTTAELSKARAGAKT

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 16546; Mature: 16546

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFKDEIQMLKRVPFFSEMEPSKLKLLAFASDRVSYHAGDTLFRQGDVGDAAYVLLTGKV
CCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEECCCCCEEECCCCCCEEEEEEECCE
DVLVDSPSGTLKVAEMTGNAIVGEIAILCDSVRTATIRASTNVEALRIGKEQFFKLMSDF
EEEEECCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCHHHHCCHHHHHHHHHCC
PDITIKVMRVLAERLTQTTAELSKARAGAKT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLFKDEIQMLKRVPFFSEMEPSKLKLLAFASDRVSYHAGDTLFRQGDVGDAAYVLLTGKV
CCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEECCCCCEEECCCCCCEEEEEEECCE
DVLVDSPSGTLKVAEMTGNAIVGEIAILCDSVRTATIRASTNVEALRIGKEQFFKLMSDF
EEEEECCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCHHHHCCHHHHHHHHHCC
PDITIKVMRVLAERLTQTTAELSKARAGAKT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA