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The map label for this gene is thiO [H]

Identifier: 159185270

GI number: 159185270

Start: 2538931

End: 2539905

Strand: Reverse

Name: thiO [H]

Synonym: Atu2568

Alternate gene names: 159185270

Gene position: 2539905-2538931 (Counterclockwise)

Preceding gene: 159185271

Following gene: 15889825

Centisome position: 89.38

GC content: 64.41

Gene sequence:

>975_bases
ATGCGTGTTCTCGTCAAGGGAACGGGGGTCGCCGGTTTGACGGCGGCCTTCGAACTGGTACGGAGTGGCGTCACCGTGGA
GGTTTCGGAGTGCCATGCCAAACCGTCCCGCGGCGCGTCCTTTTTTGCAGGCGGCATGCTGGCGCCCTGGTGTGAGCGTG
AAAGCGCGGAAGAGGCGGTTCTGACACTCGGCCAGGCGGCGCTTGACTGGTGGGATGAAGCGACGCCCGACCTTGTGGTC
CGCAACGGCACGCTGGTGGTCGCGCCCGCCCGTGACAAAGCGGAGCTTTTGCGTTTCGCATCGCGGACCAGCGGCTATCG
CTGGGTGGACGAGGCCGAAATCGCCGATCTGGAGCCCGATCTTGCAGGCCGCTTCCGGTCCGGGCTTTATTTTCCGGATG
AGGGGCATCTCGATCCGCGCCTTGCGCTTGCATCGCTGTATCAACGGCTTTGCAGCATGGGTGTGCGGTTTCATATGGGT
GTACCCGTGGATGAACGGCCGTTCGACCGGGTGGTGGATTGCACCGGGCCTGCGGCAGTGGGCAAGATTCCCCGCCTTCG
TGGTGTGCGGGGAGAGATGCTCTATCTCGCCACGTCGGAGGTTTCTCTCTCCCGTCCCGTCCGGCTGCTGCATCCGCGCA
TTCCGCTCTACGTCGTGCCGCGCGAGCCCGGCCGTTTCATGGTGGGCGCGACGATGATCGAGACGGAGGACGCGGGGGCA
ATTTCCGCCCGTTCGATGATGGAATTCCTCAATGCCGCCTATGCCGTGCACCCGGCCTTCGCGGAAGCGGAGATCATCGA
GACCGGCACGGGCGTGCGTCCCGCCTATCCCGATAATCTGCCCGACGTCACCGAGGACGGGCGGACGATCTTCATCAACG
GCGCGTACCGGCATGGCTTTCTGCTCTCGCCGGCGATGGCGCGAAAGGCGGCCGGCATCGCCTGCCAAACTCTCTCGAAA
GGAACAGGATCATGA

Upstream 100 bases:

>100_bases
GCCGAGGCGCAGAAGGAGGGACTGGAAGCCATGGCCGCCCGCTTCAAGGAGGGTGGTGAGCTTTATATGCCGCTGCCGAC
GCCCGCGAGCGCTGAATAAA

Downstream 100 bases:

>100_bases
AACTTCTTGTCAATGGCGACGAGCTTGATCTCGCTGCCGAGACGCTGGCCGGTCTGCTCGCCAGTCTCGACTACGAAGGC
GAGTGGCTGGCGACAGCGGT

Product: thiamine biosynthesis oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MRVLVKGTGVAGLTAAFELVRSGVTVEVSECHAKPSRGASFFAGGMLAPWCERESAEEAVLTLGQAALDWWDEATPDLVV
RNGTLVVAPARDKAELLRFASRTSGYRWVDEAEIADLEPDLAGRFRSGLYFPDEGHLDPRLALASLYQRLCSMGVRFHMG
VPVDERPFDRVVDCTGPAAVGKIPRLRGVRGEMLYLATSEVSLSRPVRLLHPRIPLYVVPREPGRFMVGATMIETEDAGA
ISARSMMEFLNAAYAVHPAFAEAEIIETGTGVRPAYPDNLPDVTEDGRTIFINGAYRHGFLLSPAMARKAAGIACQTLSK
GTGS

Sequences:

>Translated_324_residues
MRVLVKGTGVAGLTAAFELVRSGVTVEVSECHAKPSRGASFFAGGMLAPWCERESAEEAVLTLGQAALDWWDEATPDLVV
RNGTLVVAPARDKAELLRFASRTSGYRWVDEAEIADLEPDLAGRFRSGLYFPDEGHLDPRLALASLYQRLCSMGVRFHMG
VPVDERPFDRVVDCTGPAAVGKIPRLRGVRGEMLYLATSEVSLSRPVRLLHPRIPLYVVPREPGRFMVGATMIETEDAGA
ISARSMMEFLNAAYAVHPAFAEAEIIETGTGVRPAYPDNLPDVTEDGRTIFINGAYRHGFLLSPAMARKAAGIACQTLSK
GTGS
>Mature_324_residues
MRVLVKGTGVAGLTAAFELVRSGVTVEVSECHAKPSRGASFFAGGMLAPWCERESAEEAVLTLGQAALDWWDEATPDLVV
RNGTLVVAPARDKAELLRFASRTSGYRWVDEAEIADLEPDLAGRFRSGLYFPDEGHLDPRLALASLYQRLCSMGVRFHMG
VPVDERPFDRVVDCTGPAAVGKIPRLRGVRGEMLYLATSEVSLSRPVRLLHPRIPLYVVPREPGRFMVGATMIETEDAGA
ISARSMMEFLNAAYAVHPAFAEAEIIETGTGVRPAYPDNLPDVTEDGRTIFINGAYRHGFLLSPAMARKAAGIACQTLSK
GTGS

Specific function: May have amino acid oxidase activity in the biosynthesis of thiazole when cysteine gives its thiol group to be inserted into the thiazole molecule and the rest of the molecule is deaminated to give pyruvic acid and ammonia [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR012727 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: NA

Molecular weight: Translated: 35079; Mature: 35079

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVKGTGVAGLTAAFELVRSGVTVEVSECHAKPSRGASFFAGGMLAPWCERESAEEAV
CEEEEECCCCHHHHHHHHHHHCCCEEEEHHHCCCCCCCCCCCCCCCCCCHHCCCCHHHHH
LTLGQAALDWWDEATPDLVVRNGTLVVAPARDKAELLRFASRTSGYRWVDEAEIADLEPD
HHHHHHHHHHHCCCCCCEEEECCEEEEECCCCHHHHHHHHHHCCCCEECCCCCCCCCCCH
LAGRFRSGLYFPDEGHLDPRLALASLYQRLCSMGVRFHMGVPVDERPFDRVVDCTGPAAV
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHCCCCCCHHH
GKIPRLRGVRGEMLYLATSEVSLSRPVRLLHPRIPLYVVPREPGRFMVGATMIETEDAGA
CCCCHHCCCCCCEEEEEECCCCCCCCHHHHCCCCCEEEEECCCCCEEEEEEEEECCCCCC
ISARSMMEFLNAAYAVHPAFAEAEIIETGTGVRPAYPDNLPDVTEDGRTIFINGAYRHGF
HHHHHHHHHHHHHHHHCCCHHCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCE
LLSPAMARKAAGIACQTLSKGTGS
EECHHHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure
MRVLVKGTGVAGLTAAFELVRSGVTVEVSECHAKPSRGASFFAGGMLAPWCERESAEEAV
CEEEEECCCCHHHHHHHHHHHCCCEEEEHHHCCCCCCCCCCCCCCCCCCHHCCCCHHHHH
LTLGQAALDWWDEATPDLVVRNGTLVVAPARDKAELLRFASRTSGYRWVDEAEIADLEPD
HHHHHHHHHHHCCCCCCEEEECCEEEEECCCCHHHHHHHHHHCCCCEECCCCCCCCCCCH
LAGRFRSGLYFPDEGHLDPRLALASLYQRLCSMGVRFHMGVPVDERPFDRVVDCTGPAAV
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHCCCCCCHHH
GKIPRLRGVRGEMLYLATSEVSLSRPVRLLHPRIPLYVVPREPGRFMVGATMIETEDAGA
CCCCHHCCCCCCEEEEEECCCCCCCCHHHHCCCCCEEEEECCCCCEEEEEEEEECCCCCC
ISARSMMEFLNAAYAVHPAFAEAEIIETGTGVRPAYPDNLPDVTEDGRTIFINGAYRHGF
HHHHHHHHHHHHHHHHCCCHHCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCE
LLSPAMARKAAGIACQTLSKGTGS
EECHHHHHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371431 [H]