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The map label for this gene is dppA [H]

Identifier: 159185251

GI number: 159185251

Start: 2486546

End: 2488141

Strand: Reverse

Name: dppA [H]

Synonym: Atu2518

Alternate gene names: 159185251

Gene position: 2488141-2486546 (Counterclockwise)

Preceding gene: 15889785

Following gene: 15889782

Centisome position: 87.56

GC content: 58.77

Gene sequence:

>1596_bases
ATGATTTCAAGACGCAACCTGCTGATTGCCGGCGCTGCCGTTCCGTTCCTGTCCTATGCGCGCATTCCGGCCTTTGCCGC
GACGCCCAAGGATATTCTGGTCGTTGCCCAGCAGCTGGACAATATGACGAGCCTTGACCCGCATGAAGGTTTCGAGGCCG
TGGGCGGTGAAATCATCTCCAACATGTATCAGAAGCTGGTGCGTGCCAACCGCGAGGATTCCACCAAGGTTGATCCGGTC
ATCGCCAAGTCCTGGGAAGCCGATGCGGACAGCAAGGTGTTCACCTTCGTGATCGGGGACGAAGCGACCTTCGCGAGCGG
CGCCAAGGTCACGGCGGAAGACGTCGCCTTCTCGCTGCAGCGCGCCATCAAGATGAACAAGAGCCCGGCCTTCATCATCA
GCCAGTTCGGCTTCACGCCTGACAATGCCGAAACGACCATCGTTGCCGCCGACGACAAGACGGTGAAGCTGACGACGGCA
AAGCCGACCGCCATCTCCTTCCTGCTTTATTGCCTTTCCGCCAATATCGGCGCCATCGTTGAAAAGAAGGCGGTTCTCGC
CAATGCTGCCGGTGAAGACCTCGGCAATGGCTGGCTGCAGAAGAACAGCGCCGGTTCCGGCGATTTCATGCTGCAGGCCT
GGAAGCCGAGCGAAAGCGTCGCGCTGATAGTCAATCCGAACGGTCCCTACAAGGGCAATATCAAGCGCATCGTGCTGCGC
CACGTTACCGATCCGTCTTCCCAGCTTTTGATGCTGCAGAAGGGCGATATCGACATTGCCCGCGACCTGACTTCCGAGCA
GCTGCGCACCGTCAAGGATGACGCCAACATCGAGTTGGAGCGCAAGTCCATCGCCTCGCTGGTTCTGATCTCGCTCAATC
AGGGCAACGAGAACCTTGCCAAGCCGCAGGTCTGGCAGGCGATCAAGTGGGCGCTGGACTACAAGGGCATGCAGGAAAAC
ATCGTGCCGCTGACGCACGAAATCCACCAGAGCTTCGAGCCGAAGGGCTTCCCGGGCGCCGTCAACGATATCCCGTACCA
GCGCGATGTCGAGAAGGCCAAAGCGCTGATGGCCGAAGCCGGTCTAGCCGATGGTTTCGAAATCAGCATGGATCACTATT
CGGCCCAGCCCTATCCTGATCTGGCGCAGGCCATCCAGGCGAACCTTGCCGATATCGGCATCAAGGTGCGTCTGCAATCG
GCTGAAAACCGTCAGGTTCTGACCAAGATGCGTGCCCGCGAGCACCAGATGGCGCTTTCCGCATGGGGCACGGATTACTT
CGATCCGCATTCCAATGCCGATGTCTTCAACATCAACAAGGACAATGGCGACGACGTGAAGTCGAAGCCCTTCCTGTGGC
GTTCACGTTTCAAGAACGACGATTTCGCCGCCAAGGCGGAAGCCGCCCGCGATGAGCGTGATCCGGCAAAGCGCATCGAG
CTTTATGAAGCCCTGCAGCGCGAGCACATGGAAAACAGCCCGTTCGTCTTCATGTTCCAGACCACGAAGACGGCTGCCTT
CCGCAAGGGCGTCTCCGGCTTTGAACTCGGCGTTCTCTCCGAGGGCAATTCCTACCACGATGCGAAGAAAGCGTGA

Upstream 100 bases:

>100_bases
TCGTTTGCTCGTGTTAATCGCGGGAAAACATAAAAAAAATGACTGGATTGGGGCAAACCCACACCGTTTCCGAAAAATAA
GGTCCGAAAGGGGATTTTCG

Downstream 100 bases:

>100_bases
CATTGAACAAGCGCGTCAAAAGCATATCGTCGATACTGGGCAGCGTCATCCTGACGCTGTTCGGTTTGATGATCATCACC
TTCATGATCGGGCGCGTCAT

Product: ABC transporter, substrate binding protein (dipeptide)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MISRRNLLIAGAAVPFLSYARIPAFAATPKDILVVAQQLDNMTSLDPHEGFEAVGGEIISNMYQKLVRANREDSTKVDPV
IAKSWEADADSKVFTFVIGDEATFASGAKVTAEDVAFSLQRAIKMNKSPAFIISQFGFTPDNAETTIVAADDKTVKLTTA
KPTAISFLLYCLSANIGAIVEKKAVLANAAGEDLGNGWLQKNSAGSGDFMLQAWKPSESVALIVNPNGPYKGNIKRIVLR
HVTDPSSQLLMLQKGDIDIARDLTSEQLRTVKDDANIELERKSIASLVLISLNQGNENLAKPQVWQAIKWALDYKGMQEN
IVPLTHEIHQSFEPKGFPGAVNDIPYQRDVEKAKALMAEAGLADGFEISMDHYSAQPYPDLAQAIQANLADIGIKVRLQS
AENRQVLTKMRAREHQMALSAWGTDYFDPHSNADVFNINKDNGDDVKSKPFLWRSRFKNDDFAAKAEAARDERDPAKRIE
LYEALQREHMENSPFVFMFQTTKTAAFRKGVSGFELGVLSEGNSYHDAKKA

Sequences:

>Translated_531_residues
MISRRNLLIAGAAVPFLSYARIPAFAATPKDILVVAQQLDNMTSLDPHEGFEAVGGEIISNMYQKLVRANREDSTKVDPV
IAKSWEADADSKVFTFVIGDEATFASGAKVTAEDVAFSLQRAIKMNKSPAFIISQFGFTPDNAETTIVAADDKTVKLTTA
KPTAISFLLYCLSANIGAIVEKKAVLANAAGEDLGNGWLQKNSAGSGDFMLQAWKPSESVALIVNPNGPYKGNIKRIVLR
HVTDPSSQLLMLQKGDIDIARDLTSEQLRTVKDDANIELERKSIASLVLISLNQGNENLAKPQVWQAIKWALDYKGMQEN
IVPLTHEIHQSFEPKGFPGAVNDIPYQRDVEKAKALMAEAGLADGFEISMDHYSAQPYPDLAQAIQANLADIGIKVRLQS
AENRQVLTKMRAREHQMALSAWGTDYFDPHSNADVFNINKDNGDDVKSKPFLWRSRFKNDDFAAKAEAARDERDPAKRIE
LYEALQREHMENSPFVFMFQTTKTAAFRKGVSGFELGVLSEGNSYHDAKKA
>Mature_531_residues
MISRRNLLIAGAAVPFLSYARIPAFAATPKDILVVAQQLDNMTSLDPHEGFEAVGGEIISNMYQKLVRANREDSTKVDPV
IAKSWEADADSKVFTFVIGDEATFASGAKVTAEDVAFSLQRAIKMNKSPAFIISQFGFTPDNAETTIVAADDKTVKLTTA
KPTAISFLLYCLSANIGAIVEKKAVLANAAGEDLGNGWLQKNSAGSGDFMLQAWKPSESVALIVNPNGPYKGNIKRIVLR
HVTDPSSQLLMLQKGDIDIARDLTSEQLRTVKDDANIELERKSIASLVLISLNQGNENLAKPQVWQAIKWALDYKGMQEN
IVPLTHEIHQSFEPKGFPGAVNDIPYQRDVEKAKALMAEAGLADGFEISMDHYSAQPYPDLAQAIQANLADIGIKVRLQS
AENRQVLTKMRAREHQMALSAWGTDYFDPHSNADVFNINKDNGDDVKSKPFLWRSRFKNDDFAAKAEAARDERDPAKRIE
LYEALQREHMENSPFVFMFQTTKTAAFRKGVSGFELGVLSEGNSYHDAKKA

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=506, Percent_Identity=30.6324110671937, Blast_Score=191, Evalue=8e-50,
Organism=Escherichia coli, GI1787052, Length=552, Percent_Identity=24.2753623188406, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1789966, Length=487, Percent_Identity=25.6673511293634, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87081878, Length=530, Percent_Identity=21.8867924528302, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1787495, Length=545, Percent_Identity=22.0183486238532, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 58530; Mature: 58530

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISRRNLLIAGAAVPFLSYARIPAFAATPKDILVVAQQLDNMTSLDPHEGFEAVGGEIIS
CCCCCCEEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
NMYQKLVRANREDSTKVDPVIAKSWEADADSKVFTFVIGDEATFASGAKVTAEDVAFSLQ
HHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEHHHHHHHHH
RAIKMNKSPAFIISQFGFTPDNAETTIVAADDKTVKLTTAKPTAISFLLYCLSANIGAIV
HHHHCCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCHHHHHHHHHHHHCCCCHHH
EKKAVLANAAGEDLGNGWLQKNSAGSGDFMLQAWKPSESVALIVNPNGPYKGNIKRIVLR
HHHHHHHHCCCCHHCCCCEECCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCHHEEEEE
HVTDPSSQLLMLQKGDIDIARDLTSEQLRTVKDDANIELERKSIASLVLISLNQGNENLA
CCCCCCHHEEEEECCCCHHHHHCCHHHHHHHCCCCCEEEEHHHHEEEEEEEECCCCCCCC
KPQVWQAIKWALDYKGMQENIVPLTHEIHQSFEPKGFPGAVNDIPYQRDVEKAKALMAEA
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GLADGFEISMDHYSAQPYPDLAQAIQANLADIGIKVRLQSAENRQVLTKMRAREHQMALS
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHHHHHH
AWGTDYFDPHSNADVFNINKDNGDDVKSKPFLWRSRFKNDDFAAKAEAARDERDPAKRIE
HCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHCCCCHHHHHH
LYEALQREHMENSPFVFMFQTTKTAAFRKGVSGFELGVLSEGNSYHDAKKA
HHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MISRRNLLIAGAAVPFLSYARIPAFAATPKDILVVAQQLDNMTSLDPHEGFEAVGGEIIS
CCCCCCEEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
NMYQKLVRANREDSTKVDPVIAKSWEADADSKVFTFVIGDEATFASGAKVTAEDVAFSLQ
HHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEHHHHHHHHH
RAIKMNKSPAFIISQFGFTPDNAETTIVAADDKTVKLTTAKPTAISFLLYCLSANIGAIV
HHHHCCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCHHHHHHHHHHHHCCCCHHH
EKKAVLANAAGEDLGNGWLQKNSAGSGDFMLQAWKPSESVALIVNPNGPYKGNIKRIVLR
HHHHHHHHCCCCHHCCCCEECCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCHHEEEEE
HVTDPSSQLLMLQKGDIDIARDLTSEQLRTVKDDANIELERKSIASLVLISLNQGNENLA
CCCCCCHHEEEEECCCCHHHHHCCHHHHHHHCCCCCEEEEHHHHEEEEEEEECCCCCCCC
KPQVWQAIKWALDYKGMQENIVPLTHEIHQSFEPKGFPGAVNDIPYQRDVEKAKALMAEA
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GLADGFEISMDHYSAQPYPDLAQAIQANLADIGIKVRLQSAENRQVLTKMRAREHQMALS
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHHHHHH
AWGTDYFDPHSNADVFNINKDNGDDVKSKPFLWRSRFKNDDFAAKAEAARDERDPAKRIE
HCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHCCCCHHHHHH
LYEALQREHMENSPFVFMFQTTKTAAFRKGVSGFELGVLSEGNSYHDAKKA
HHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]