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The map label for this gene is engD [H]

Identifier: 159185112

GI number: 159185112

Start: 2204639

End: 2205742

Strand: Direct

Name: engD [H]

Synonym: Atu2233

Alternate gene names: 159185112

Gene position: 2204639-2205742 (Clockwise)

Preceding gene: 15889507

Following gene: 159185113

Centisome position: 77.58

GC content: 60.78

Gene sequence:

>1104_bases
ATGGGCTTCAAATGCGGTATCGTTGGATTGCCAAATGTCGGCAAGTCCACCCTCTTCAACGCGCTGACGAAAACGGCCGC
CGCACAGGCTGCCAACTATCCCTTCTGCACCATCGAGCCGAATACCGGCGAAGTTGCCGTGCCGGATCCGCGTATGCAGC
AGCTTGCGGCCATCGCCGGTTCGAAGGAAATCATTCCGACCCGCATTTCCTTCGTGGACATTGCCGGCCTGGTGCGCGGC
GCGTCAAAGGGTGAAGGCCTCGGCAACAAGTTCCTCGCCAACATCCGCGAAGTCGATGCCGTCGTGCATGTGCTGCGCTG
CTTCGAAGACGACGATATCACCCATGTGGAAGGCCGCATCAATCCGGTTGGCGACGCCGAAACGATCGAGACCGAACTGA
TGCTCGCCGACCTCGAAAGCCTGGAGCGCCGTGTCGAGCAGACGCGCAAGCGCGCCACCAGCAAGGACAAGGAATCCCTG
GCTCAACTGCCGGTCATGGAAGCGGTCATCGCGCTGCTCAACGACGGAAAGCCGGCACGCCTGCTGTTGAAGACGCTGGC
GGACGAGGAAATCGAAATCCTCAAAGGCCTCAATCTCCTGACGTCGCACCCGGTGCTGTATGTCTGCAACGTCTCGGAAG
CCGACGCATCGTCCGGCAACGAGCACACCGCAGCCGTCGCAGAGATGGCAAAGCAGCAGGGTGCTGAATGCGTGATCATC
TCGGCGGCGATCGAGGCCGAAGTTGCACAGCTTCCGGCCGATGAAGCCGAGGAATTCCTCTCGGCCCTCGGCCTTAACGA
AGCTGGTCTCGACCGGCTCATCCGTGCCGGTTATCACCTGCTCGACCTCATCACCTATTTCACCGTCGGCCCGAAGGAAA
CGCGCGCCTGGACGATCGTGCGCGGCACCAAAGCCCCCGCCGCCGCCGGCGTCATCCATACCGATTTCGAACGCGGCTTC
ATCCGCGCCTTCACCATCGGTTTTGACGACTACATCGCCTATAAGGGCGAAGTCGGCGCCAAGGAAGCGGGTAAGGGACG
TGACGAAGGCAAGGAATATGTCGTTCAGGACGGCGACGTCATCCACTTCCGCTTTAACACCTGA

Upstream 100 bases:

>100_bases
GGGCTTTGCCGGCACAAATCGGCTCGCGGGCTTGACCTTGCCCTGCCCATTCCGCAAAAGGCTCCTCAACGAATTCTTTC
AAACGGACAGGTTTCAAGCC

Downstream 100 bases:

>100_bases
TCTGGTTTGAACGACGGTTCGAATGAAGCCACCCGGACAATGCGGCACATTTCTTCTCCCCGCCGGGGAGAAGATGTCCG
AAGGGACAGATGAGGGGGCC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MGFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRMQQLAAIAGSKEIIPTRISFVDIAGLVRG
ASKGEGLGNKFLANIREVDAVVHVLRCFEDDDITHVEGRINPVGDAETIETELMLADLESLERRVEQTRKRATSKDKESL
AQLPVMEAVIALLNDGKPARLLLKTLADEEIEILKGLNLLTSHPVLYVCNVSEADASSGNEHTAAVAEMAKQQGAECVII
SAAIEAEVAQLPADEAEEFLSALGLNEAGLDRLIRAGYHLLDLITYFTVGPKETRAWTIVRGTKAPAAAGVIHTDFERGF
IRAFTIGFDDYIAYKGEVGAKEAGKGRDEGKEYVVQDGDVIHFRFNT

Sequences:

>Translated_367_residues
MGFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRMQQLAAIAGSKEIIPTRISFVDIAGLVRG
ASKGEGLGNKFLANIREVDAVVHVLRCFEDDDITHVEGRINPVGDAETIETELMLADLESLERRVEQTRKRATSKDKESL
AQLPVMEAVIALLNDGKPARLLLKTLADEEIEILKGLNLLTSHPVLYVCNVSEADASSGNEHTAAVAEMAKQQGAECVII
SAAIEAEVAQLPADEAEEFLSALGLNEAGLDRLIRAGYHLLDLITYFTVGPKETRAWTIVRGTKAPAAAGVIHTDFERGF
IRAFTIGFDDYIAYKGEVGAKEAGKGRDEGKEYVVQDGDVIHFRFNT
>Mature_366_residues
GFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRMQQLAAIAGSKEIIPTRISFVDIAGLVRGA
SKGEGLGNKFLANIREVDAVVHVLRCFEDDDITHVEGRINPVGDAETIETELMLADLESLERRVEQTRKRATSKDKESLA
QLPVMEAVIALLNDGKPARLLLKTLADEEIEILKGLNLLTSHPVLYVCNVSEADASSGNEHTAAVAEMAKQQGAECVIIS
AAIEAEVAQLPADEAEEFLSALGLNEAGLDRLIRAGYHLLDLITYFTVGPKETRAWTIVRGTKAPAAAGVIHTDFERGFI
RAFTIGFDDYIAYKGEVGAKEAGKGRDEGKEYVVQDGDVIHFRFNT

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=43.6314363143631, Blast_Score=299, Evalue=3e-81,
Organism=Homo sapiens, GI58761502, Length=215, Percent_Identity=39.0697674418605, Blast_Score=156, Evalue=3e-38,
Organism=Escherichia coli, GI1787454, Length=366, Percent_Identity=57.3770491803279, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1789574, Length=130, Percent_Identity=33.0769230769231, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17509631, Length=369, Percent_Identity=43.0894308943089, Blast_Score=286, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6319499, Length=372, Percent_Identity=41.3978494623656, Blast_Score=276, Evalue=5e-75,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=36.6754617414248, Blast_Score=224, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6321649, Length=317, Percent_Identity=27.4447949526814, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640873, Length=369, Percent_Identity=42.0054200542005, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24640877, Length=369, Percent_Identity=42.0054200542005, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24640875, Length=369, Percent_Identity=42.0054200542005, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24640879, Length=329, Percent_Identity=39.5136778115502, Blast_Score=225, Evalue=4e-59,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39565; Mature: 39434

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00626 RCC1_2 ; PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRMQQLAAIAG
CCEEECEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHHHHHHHHCC
SKEIIPTRISFVDIAGLVRGASKGEGLGNKFLANIREVDAVVHVLRCFEDDDITHVEGRI
CCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
NPVGDAETIETELMLADLESLERRVEQTRKRATSKDKESLAQLPVMEAVIALLNDGKPAR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHCCCCHHH
LLLKTLADEEIEILKGLNLLTSHPVLYVCNVSEADASSGNEHTAAVAEMAKQQGAECVII
HHHHHHCCHHHHHHHCCHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
SAAIEAEVAQLPADEAEEFLSALGLNEAGLDRLIRAGYHLLDLITYFTVGPKETRAWTIV
EHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
RGTKAPAAAGVIHTDFERGFIRAFTIGFDDYIAYKGEVGAKEAGKGRDEGKEYVVQDGDV
ECCCCCCCCCCEECCCCCCEEEEEEECCHHHEEECCCCCCCCCCCCCCCCCEEEEECCCE
IHFRFNT
EEEEECC
>Mature Secondary Structure 
GFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRMQQLAAIAG
CEEECEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHHHHHHHHCC
SKEIIPTRISFVDIAGLVRGASKGEGLGNKFLANIREVDAVVHVLRCFEDDDITHVEGRI
CCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
NPVGDAETIETELMLADLESLERRVEQTRKRATSKDKESLAQLPVMEAVIALLNDGKPAR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHCCCCHHH
LLLKTLADEEIEILKGLNLLTSHPVLYVCNVSEADASSGNEHTAAVAEMAKQQGAECVII
HHHHHHCCHHHHHHHCCHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
SAAIEAEVAQLPADEAEEFLSALGLNEAGLDRLIRAGYHLLDLITYFTVGPKETRAWTIV
EHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
RGTKAPAAAGVIHTDFERGFIRAFTIGFDDYIAYKGEVGAKEAGKGRDEGKEYVVQDGDV
ECCCCCCCCCCEECCCCCCEEEEEEECCHHHEEECCCCCCCCCCCCCCCCCEEEEECCCE
IHFRFNT
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA