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The map label for this gene is degQ [H]

Identifier: 159184977

GI number: 159184977

Start: 1892100

End: 1893506

Strand: Reverse

Name: degQ [H]

Synonym: Atu1915

Alternate gene names: 159184977

Gene position: 1893506-1892100 (Counterclockwise)

Preceding gene: 15889211

Following gene: 15889208

Centisome position: 66.64

GC content: 62.12

Gene sequence:

>1407_bases
ATGCGAGGCGTGTTGAAGTATCTGTCCACCGGCTTTCTTGCTGCGCTCGTTCTCCTGCCCGTGGGCGCAAGAGCGCAGGA
CAACAAGACCGTGCCGGCAAGCCACACGGAAATGCAGCTCTCCTTCGCGCCGCTGGTGAAGCGCACCGCAGGTGCTGTGG
TGAATGTCTATGCCGAGCGCGTCGTGCAGCGGCGTGTTTCCCCTTTTGCCGGTGATCCCTTCTTCGAGCAGTTTTTCGGC
CAGCAAATGCCGAACCGTACGGAAAAGCAGTCATCGCTCGGTTCGGGCGTGATCGTAACGGCGGGCGGCCTCGTGGTGAC
GAACAATCACGTCATCGACGGCGCTGATGACATCAAGGTGGCGCTGGCGGATGGTCGCGAGTTTTCCTCCAAGGTGCTGA
TGAAGGACGATCGGGTTGATCTCGCCGTGTTGCAGATTGACGCCAAGGAGCAATTCCCCGTGCTGTCGCTCGGCGATTCC
GACAAGATCGAGGTTGGTGATCTGGTGCTCGCCATCGGCAACCCCTTCGGGGTCGGCCAGACGGTGACGAGCGGCATCGT
CTCCGGTCTAGCGCGCAACCAGGTGACGCAGGGTGATTTCGGCTTCTTCATCCAGACCGACGCCTCCATCAACCCCGGCA
ATTCCGGCGGTGCGCTGATGAACATGGCGGGCGAGCTGGTCGGCATCAATACCGCGATCTTTTCCAAGGGCGGCGGGTCG
AACGGCATCGGTTTTGCCATTCCCGCCAATCTGGTTCGGGTTTTCGTAGCGGCCGCGGAGCGCGGCGACGCTAACTTCCA
GAGGCCCTATATCGGTGCAACGTTCGATCCGGTGACGTCAGATGTCGCGGAAGCGCTCGGCTTGCATCGCGCGCGCGGCG
CGCTCGTCGTCGGCGTCACCAAGGGTGGTCCGGCGGAGAAGGCTGGTATCGAGCCCGGACAGGTGGTGACTGCGGTCAAT
GGCCTGGAAGTGGAGCATCCCGATGCGCTGGGTTATCGCCTGACGACGGCCGGCATCGGCAAATCGGCCGAATTGACGGT
GGTGGAAAAGGGCAAAGAAAAGAAGCTGACCATCGCTCTCAATACGGCACCCGAAACCGCGCCGCGTGACGAGCGGCTGC
TCGAAGGCCGCAATCCCTTCGCAGGTGCTACCGTCGCCAACCTCTCGCCGAAGCTTGCGGATGAATTGCGCATGCCTTCG
CAGGTGACGGGCGTCGTCATCACCGATGTGAAGCGTGGCTCACCGGCCTATCGCGTCGGTTTCCAGCCGAAGGATGTCAT
CCTGTCGCTGAATGGTGCGGATATCGGCTCCACCGCTGCGGTTGAAAAGGCGCTGGACGACAATCCCGGCTTCTGGCGGG
TGGAAATCCTGCGCGACGGGCAGCGTATCCGGCAGTTCCTGCGATGA

Upstream 100 bases:

>100_bases
CCGATCTCTGCCGGGATAAGTGTGGCCATCATCTTGCCGCTCTTTGCTTTACAGGCTTTGGCGTTATAACTCCATCATAC
TGATGACGATGAGGAATCAC

Downstream 100 bases:

>100_bases
GCGACGATCTCTTTGCCCCGCAAGTGCCTGTGGAGGTCGCCAACCGGCGGCCTCTGGCCGATCGTCTGCGTCCGAAAACG
CTGTCGGAGGTGAGTGGGCA

Product: htrA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MRGVLKYLSTGFLAALVLLPVGARAQDNKTVPASHTEMQLSFAPLVKRTAGAVVNVYAERVVQRRVSPFAGDPFFEQFFG
QQMPNRTEKQSSLGSGVIVTAGGLVVTNNHVIDGADDIKVALADGREFSSKVLMKDDRVDLAVLQIDAKEQFPVLSLGDS
DKIEVGDLVLAIGNPFGVGQTVTSGIVSGLARNQVTQGDFGFFIQTDASINPGNSGGALMNMAGELVGINTAIFSKGGGS
NGIGFAIPANLVRVFVAAAERGDANFQRPYIGATFDPVTSDVAEALGLHRARGALVVGVTKGGPAEKAGIEPGQVVTAVN
GLEVEHPDALGYRLTTAGIGKSAELTVVEKGKEKKLTIALNTAPETAPRDERLLEGRNPFAGATVANLSPKLADELRMPS
QVTGVVITDVKRGSPAYRVGFQPKDVILSLNGADIGSTAAVEKALDDNPGFWRVEILRDGQRIRQFLR

Sequences:

>Translated_468_residues
MRGVLKYLSTGFLAALVLLPVGARAQDNKTVPASHTEMQLSFAPLVKRTAGAVVNVYAERVVQRRVSPFAGDPFFEQFFG
QQMPNRTEKQSSLGSGVIVTAGGLVVTNNHVIDGADDIKVALADGREFSSKVLMKDDRVDLAVLQIDAKEQFPVLSLGDS
DKIEVGDLVLAIGNPFGVGQTVTSGIVSGLARNQVTQGDFGFFIQTDASINPGNSGGALMNMAGELVGINTAIFSKGGGS
NGIGFAIPANLVRVFVAAAERGDANFQRPYIGATFDPVTSDVAEALGLHRARGALVVGVTKGGPAEKAGIEPGQVVTAVN
GLEVEHPDALGYRLTTAGIGKSAELTVVEKGKEKKLTIALNTAPETAPRDERLLEGRNPFAGATVANLSPKLADELRMPS
QVTGVVITDVKRGSPAYRVGFQPKDVILSLNGADIGSTAAVEKALDDNPGFWRVEILRDGQRIRQFLR
>Mature_468_residues
MRGVLKYLSTGFLAALVLLPVGARAQDNKTVPASHTEMQLSFAPLVKRTAGAVVNVYAERVVQRRVSPFAGDPFFEQFFG
QQMPNRTEKQSSLGSGVIVTAGGLVVTNNHVIDGADDIKVALADGREFSSKVLMKDDRVDLAVLQIDAKEQFPVLSLGDS
DKIEVGDLVLAIGNPFGVGQTVTSGIVSGLARNQVTQGDFGFFIQTDASINPGNSGGALMNMAGELVGINTAIFSKGGGS
NGIGFAIPANLVRVFVAAAERGDANFQRPYIGATFDPVTSDVAEALGLHRARGALVVGVTKGGPAEKAGIEPGQVVTAVN
GLEVEHPDALGYRLTTAGIGKSAELTVVEKGKEKKLTIALNTAPETAPRDERLLEGRNPFAGATVANLSPKLADELRMPS
QVTGVVITDVKRGSPAYRVGFQPKDVILSLNGADIGSTAAVEKALDDNPGFWRVEILRDGQRIRQFLR

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=245, Percent_Identity=38.3673469387755, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI7019477, Length=346, Percent_Identity=33.5260115606936, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI24308541, Length=241, Percent_Identity=34.8547717842324, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI22129776, Length=305, Percent_Identity=32.4590163934426, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1789629, Length=468, Percent_Identity=37.6068376068376, Blast_Score=259, Evalue=4e-70,
Organism=Escherichia coli, GI1786356, Length=472, Percent_Identity=36.0169491525424, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1789630, Length=324, Percent_Identity=37.037037037037, Blast_Score=162, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24646839, Length=309, Percent_Identity=32.0388349514563, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 49271; Mature: 49271

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGVLKYLSTGFLAALVLLPVGARAQDNKTVPASHTEMQLSFAPLVKRTAGAVVNVYAER
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
VVQRRVSPFAGDPFFEQFFGQQMPNRTEKQSSLGSGVIVTAGGLVVTNNHVIDGADDIKV
HHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCEEEECCEEECCCCCEEE
ALADGREFSSKVLMKDDRVDLAVLQIDAKEQFPVLSLGDSDKIEVGDLVLAIGNPFGVGQ
EEECCCCCCCEEEEECCCCEEEEEEECCCCCCCEEECCCCCCEEECEEEEEECCCCCCCH
TVTSGIVSGLARNQVTQGDFGFFIQTDASINPGNSGGALMNMAGELVGINTAIFSKGGGS
HHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHCCCEEECEEEEEECCCCC
NGIGFAIPANLVRVFVAAAERGDANFQRPYIGATFDPVTSDVAEALGLHRARGALVVGVT
CCCCEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEE
KGGPAEKAGIEPGQVVTAVNGLEVEHPDALGYRLTTAGIGKSAELTVVEKGKEKKLTIAL
CCCCCHHCCCCCCCEEEEECCCEECCCCCCCEEEEECCCCCCCEEEEEECCCCCEEEEEE
NTAPETAPRDERLLEGRNPFAGATVANLSPKLADELRMPSQVTGVVITDVKRGSPAYRVG
ECCCCCCCCHHHHHCCCCCCCCCCHHCCCHHHHHHHCCCCHHCEEEEEEECCCCCCEEEC
FQPKDVILSLNGADIGSTAAVEKALDDNPGFWRVEILRDGQRIRQFLR
CCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEECCCHHHHHHHC
>Mature Secondary Structure
MRGVLKYLSTGFLAALVLLPVGARAQDNKTVPASHTEMQLSFAPLVKRTAGAVVNVYAER
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
VVQRRVSPFAGDPFFEQFFGQQMPNRTEKQSSLGSGVIVTAGGLVVTNNHVIDGADDIKV
HHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCEEEECCEEECCCCCEEE
ALADGREFSSKVLMKDDRVDLAVLQIDAKEQFPVLSLGDSDKIEVGDLVLAIGNPFGVGQ
EEECCCCCCCEEEEECCCCEEEEEEECCCCCCCEEECCCCCCEEECEEEEEECCCCCCCH
TVTSGIVSGLARNQVTQGDFGFFIQTDASINPGNSGGALMNMAGELVGINTAIFSKGGGS
HHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHCCCEEECEEEEEECCCCC
NGIGFAIPANLVRVFVAAAERGDANFQRPYIGATFDPVTSDVAEALGLHRARGALVVGVT
CCCCEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEE
KGGPAEKAGIEPGQVVTAVNGLEVEHPDALGYRLTTAGIGKSAELTVVEKGKEKKLTIAL
CCCCCHHCCCCCCCEEEEECCCEECCCCCCCEEEEECCCCCCCEEEEEECCCCCEEEEEE
NTAPETAPRDERLLEGRNPFAGATVANLSPKLADELRMPSQVTGVVITDVKRGSPAYRVG
ECCCCCCCCHHHHHCCCCCCCCCCHHCCCHHHHHHHCCCCHHCEEEEEEECCCCCCEEEC
FQPKDVILSLNGADIGSTAAVEKALDDNPGFWRVEILRDGQRIRQFLR
CCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEECCCHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]