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The map label for this gene is recG [H]

Identifier: 159184915

GI number: 159184915

Start: 1766494

End: 1768599

Strand: Direct

Name: recG [H]

Synonym: Atu1780

Alternate gene names: 159184915

Gene position: 1766494-1768599 (Clockwise)

Preceding gene: 159184913

Following gene: 15889085

Centisome position: 62.17

GC content: 64.2

Gene sequence:

>2106_bases
ATGCGCCCGGCCATTCTCGATCCGCTGTTTGCTTCCGTCTCCACCCTTGCCGGCGTGGGGCCGAAGCTTGCCGACCTTTT
GGCAAAACTGCTGAGCCGGGAAAGCGCCGACGACACCCGCGTGATCGACCTCCTGTTCCACGCGCCATCAAACGTCATTG
ACCGGCGTAACCGCCCGGGCATCGCGCTTGCCGCCCCCGGCGCCATTGTCACCATTCAGGGACGCGTCGACCGGCACCAA
CCGCCACCCGCAGGCAATCGCTCCGCCCCCTATCGCGTGTTCCTGCATGACGAGACCGGCGAACTGGCGCTGACCTTCTT
CCGCGCCAAGGGCGACTGGCTGTCCAAGGCCCTGCCCGTCGATGAAGAGGTTCTCGTTAGCGGCAAGGTGGACTGGTTCA
ACGGCCGCGCCTCCATGGTACACCCGGATTTCATGGTGAAGCTTTCCGAGGCGGAAAACCTGCCCTTGGTGGAAGCGGTT
TATCCCATGACGGCCGGGCTCTCCCCTAAAGTGCTGCGGCGGGCGATCGAAGGTGGGCTATCGAAGCTGCCGGTCTTCCC
GGAATGGATCGACGAGACGCTCAAGACCCGGCAGGGCTTCGGCGATGTCGCATCGAGCTTCCGCGAGCTGCATGACCCGC
GCGACAGCGCAGATATCGACCCGCAGGCCCCGGCGCGCAGACGGCTCGCCTATGACGAATTCCTCGCCGGGCAGCTATCA
CTGGCGCTGGTGCGCCAAAGACTGCGCAAGGTGGCAGGCCAGCCGATCCGCGCCAGGGGTGATATCGCCGCAAAAATCCT
GTCGCAGCTGCCCTTCTCGCTGACGGCAAGCCAGAGTGCGGCGGTGAAGGACATCCTCACCGATATGGCGGGCGAAGACC
GCATGTTGCGGCTGCTGCAGGGCGACGTCGGCGCCGGCAAGACGCTGGTAGCGCTGATGGCCATGGCGACGGCGGTGGAG
GCCGGCGGACAGGCGGTGCTGATGGCGCCGACTGAAATCCTTGCCCGCCAACACTTCGCCACCATATCTAAACTTGCAAA
GGCCGTAGGGCTTACAGTCGAGGTGCTTACCGGCCGCACCAAGGGCAAGGAACGCCGCGAGATCGAGGAGCGTGTGGCGT
CAGGCGAAGCGCAGATCGTCATCGGCACGCACGCGCTGTTTCAGGACAGCGTGAGTTACAAAAACCTCGTGCTGGCCGTG
GTGGACGAACAGCACCGTTTCGGCGTGCATCAGCGCCTGCGTCTTACTGCCAAGGGCATCACGCCCCATATGCTGGTCAT
GACCGCCACCCCCATTCCGCGCACGCTGGTTCTGGCCGCCTTCGGCGACATGGATGTGTCGAAACTCACCGAAAAACCGG
CTGGCCGCAAACCCATCCAGACCGTGACCATCCCGACTGAGCGCATTGGCGATATTGTCGAGCGTCTGCGTGCGGCGCTG
AAGGACGGTAAGAAGGCCTACTGGATCTGCCCGCTGGTTGAGGAAACGGAAGAGTCCGACCTGATGTCGGCAGAGGAACG
GCATGCGGTTCTGTCGCAGATGCTCGGCGCCAATATAGGCCTCATCCATGGCCGTATGAATGGCCCGGAGAAGGACGCCG
CCATGCTCGCTTTCAAGAGTGGCGAAACCCGGCTGCTGGTGGCAACGACGGTAGTGGAAGTGGGCGTCGACGTTCCGGAT
GCGACGATCATGGTCATCGAACATGCCGAACGTTTCGGCCTTGCCCAGCTGCACCAGCTGCGCGGCCGCGTCGGGCGTGG
CGATGAGGCCTCTACCTGCATCCTGCTCTACAAGGGGCCGCTCAGCGAAAACGGCCGCGCCCGACTTTCCATCCTGCGTG
ACAGCGAGGACGGCTTCCTGATCGCGGAAGAGGATCTGAAGCTGCGCGGAGAAGGCGAACTGCTCGGCACCCGCCAGTCC
GGCACGCCGGGCTTCCGTATCGCCAGCCTCGAAGCCCATGCCGATCTCCTGGAAATCGCCCGCAAGGACGCGGCCTATGT
CATCGAGCGCGACCCCGAATTGACCGGTCCGCGCGGGGAAAGCCTGCGCACCCTGCTCTATCTGCACCGCCGCGACGAAG
CGATCCGCTTCCTGCATGCCGGCTGA

Upstream 100 bases:

>100_bases
TCGAAATAATGCCACGGCGGCTAAAATCTGCCGGTGATAAACCGCGTTTGTCGAGGCCCGCGTCTTGCATAACGCGTCCC
CTTCCCCGATTTTGCTGACC

Downstream 100 bases:

>100_bases
AAGTGAACAACCATGAACATGATCGACCCGCGCCGCCCACCGCCCGCCTTCAGAAAGGGCTACGCGCTCTGCTCACCGCA
AAACGTCCTGCAACCCGACA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 701; Mature: 701

Protein sequence:

>701_residues
MRPAILDPLFASVSTLAGVGPKLADLLAKLLSRESADDTRVIDLLFHAPSNVIDRRNRPGIALAAPGAIVTIQGRVDRHQ
PPPAGNRSAPYRVFLHDETGELALTFFRAKGDWLSKALPVDEEVLVSGKVDWFNGRASMVHPDFMVKLSEAENLPLVEAV
YPMTAGLSPKVLRRAIEGGLSKLPVFPEWIDETLKTRQGFGDVASSFRELHDPRDSADIDPQAPARRRLAYDEFLAGQLS
LALVRQRLRKVAGQPIRARGDIAAKILSQLPFSLTASQSAAVKDILTDMAGEDRMLRLLQGDVGAGKTLVALMAMATAVE
AGGQAVLMAPTEILARQHFATISKLAKAVGLTVEVLTGRTKGKERREIEERVASGEAQIVIGTHALFQDSVSYKNLVLAV
VDEQHRFGVHQRLRLTAKGITPHMLVMTATPIPRTLVLAAFGDMDVSKLTEKPAGRKPIQTVTIPTERIGDIVERLRAAL
KDGKKAYWICPLVEETEESDLMSAEERHAVLSQMLGANIGLIHGRMNGPEKDAAMLAFKSGETRLLVATTVVEVGVDVPD
ATIMVIEHAERFGLAQLHQLRGRVGRGDEASTCILLYKGPLSENGRARLSILRDSEDGFLIAEEDLKLRGEGELLGTRQS
GTPGFRIASLEAHADLLEIARKDAAYVIERDPELTGPRGESLRTLLYLHRRDEAIRFLHAG

Sequences:

>Translated_701_residues
MRPAILDPLFASVSTLAGVGPKLADLLAKLLSRESADDTRVIDLLFHAPSNVIDRRNRPGIALAAPGAIVTIQGRVDRHQ
PPPAGNRSAPYRVFLHDETGELALTFFRAKGDWLSKALPVDEEVLVSGKVDWFNGRASMVHPDFMVKLSEAENLPLVEAV
YPMTAGLSPKVLRRAIEGGLSKLPVFPEWIDETLKTRQGFGDVASSFRELHDPRDSADIDPQAPARRRLAYDEFLAGQLS
LALVRQRLRKVAGQPIRARGDIAAKILSQLPFSLTASQSAAVKDILTDMAGEDRMLRLLQGDVGAGKTLVALMAMATAVE
AGGQAVLMAPTEILARQHFATISKLAKAVGLTVEVLTGRTKGKERREIEERVASGEAQIVIGTHALFQDSVSYKNLVLAV
VDEQHRFGVHQRLRLTAKGITPHMLVMTATPIPRTLVLAAFGDMDVSKLTEKPAGRKPIQTVTIPTERIGDIVERLRAAL
KDGKKAYWICPLVEETEESDLMSAEERHAVLSQMLGANIGLIHGRMNGPEKDAAMLAFKSGETRLLVATTVVEVGVDVPD
ATIMVIEHAERFGLAQLHQLRGRVGRGDEASTCILLYKGPLSENGRARLSILRDSEDGFLIAEEDLKLRGEGELLGTRQS
GTPGFRIASLEAHADLLEIARKDAAYVIERDPELTGPRGESLRTLLYLHRRDEAIRFLHAG
>Mature_701_residues
MRPAILDPLFASVSTLAGVGPKLADLLAKLLSRESADDTRVIDLLFHAPSNVIDRRNRPGIALAAPGAIVTIQGRVDRHQ
PPPAGNRSAPYRVFLHDETGELALTFFRAKGDWLSKALPVDEEVLVSGKVDWFNGRASMVHPDFMVKLSEAENLPLVEAV
YPMTAGLSPKVLRRAIEGGLSKLPVFPEWIDETLKTRQGFGDVASSFRELHDPRDSADIDPQAPARRRLAYDEFLAGQLS
LALVRQRLRKVAGQPIRARGDIAAKILSQLPFSLTASQSAAVKDILTDMAGEDRMLRLLQGDVGAGKTLVALMAMATAVE
AGGQAVLMAPTEILARQHFATISKLAKAVGLTVEVLTGRTKGKERREIEERVASGEAQIVIGTHALFQDSVSYKNLVLAV
VDEQHRFGVHQRLRLTAKGITPHMLVMTATPIPRTLVLAAFGDMDVSKLTEKPAGRKPIQTVTIPTERIGDIVERLRAAL
KDGKKAYWICPLVEETEESDLMSAEERHAVLSQMLGANIGLIHGRMNGPEKDAAMLAFKSGETRLLVATTVVEVGVDVPD
ATIMVIEHAERFGLAQLHQLRGRVGRGDEASTCILLYKGPLSENGRARLSILRDSEDGFLIAEEDLKLRGEGELLGTRQS
GTPGFRIASLEAHADLLEIARKDAAYVIERDPELTGPRGESLRTLLYLHRRDEAIRFLHAG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=675, Percent_Identity=42.6666666666667, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1787357, Length=403, Percent_Identity=37.9652605459057, Blast_Score=231, Evalue=8e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76450; Mature: 76450

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAILDPLFASVSTLAGVGPKLADLLAKLLSRESADDTRVIDLLFHAPSNVIDRRNRPG
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHEEHHHHHCCHHHHHCCCCCC
IALAAPGAIVTIQGRVDRHQPPPAGNRSAPYRVFLHDETGELALTFFRAKGDWLSKALPV
EEEECCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCHHHHCCCC
DEEVLVSGKVDWFNGRASMVHPDFMVKLSEAENLPLVEAVYPMTAGLSPKVLRRAIEGGL
CCCEEEECCEEEECCCCCEECCHHEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCH
SKLPVFPEWIDETLKTRQGFGDVASSFRELHDPRDSADIDPQAPARRRLAYDEFLAGQLS
HCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LALVRQRLRKVAGQPIRARGDIAAKILSQLPFSLTASQSAAVKDILTDMAGEDRMLRLLQ
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCHHHHHHHH
GDVGAGKTLVALMAMATAVEAGGQAVLMAPTEILARQHFATISKLAKAVGLTVEVLTGRT
CCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
KGKERREIEERVASGEAQIVIGTHALFQDSVSYKNLVLAVVDEQHRFGVHQRLRLTAKGI
CCHHHHHHHHHHHCCCEEEEEEEHHHHHCCCCCCEEEEEEECCHHHCCHHHHHEEEECCC
TPHMLVMTATPIPRTLVLAAFGDMDVSKLTEKPAGRKPIQTVTIPTERIGDIVERLRAAL
CCEEEEEECCCCCCEEEEEECCCCCHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHH
KDGKKAYWICPLVEETEESDLMSAEERHAVLSQMLGANIGLIHGRMNGPEKDAAMLAFKS
HCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEEC
GETRLLVATTVVEVGVDVPDATIMVIEHAERFGLAQLHQLRGRVGRGDEASTCILLYKGP
CCCEEEEEEEEHHHCCCCCCCEEEEEECHHHCCHHHHHHHHCCCCCCCCCCEEEEEEECC
LSENGRARLSILRDSEDGFLIAEEDLKLRGEGELLGTRQSGTPGFRIASLEAHADLLEIA
CCCCCCEEEEEEEECCCCEEEECCCCEEECCCCEEEECCCCCCCEEEEEEHHHHHHHHHH
RKDAAYVIERDPELTGPRGESLRTLLYLHRRDEAIRFLHAG
HCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHEECC
>Mature Secondary Structure
MRPAILDPLFASVSTLAGVGPKLADLLAKLLSRESADDTRVIDLLFHAPSNVIDRRNRPG
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHEEHHHHHCCHHHHHCCCCCC
IALAAPGAIVTIQGRVDRHQPPPAGNRSAPYRVFLHDETGELALTFFRAKGDWLSKALPV
EEEECCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCHHHHCCCC
DEEVLVSGKVDWFNGRASMVHPDFMVKLSEAENLPLVEAVYPMTAGLSPKVLRRAIEGGL
CCCEEEECCEEEECCCCCEECCHHEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCH
SKLPVFPEWIDETLKTRQGFGDVASSFRELHDPRDSADIDPQAPARRRLAYDEFLAGQLS
HCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LALVRQRLRKVAGQPIRARGDIAAKILSQLPFSLTASQSAAVKDILTDMAGEDRMLRLLQ
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCHHHHHHHH
GDVGAGKTLVALMAMATAVEAGGQAVLMAPTEILARQHFATISKLAKAVGLTVEVLTGRT
CCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
KGKERREIEERVASGEAQIVIGTHALFQDSVSYKNLVLAVVDEQHRFGVHQRLRLTAKGI
CCHHHHHHHHHHHCCCEEEEEEEHHHHHCCCCCCEEEEEEECCHHHCCHHHHHEEEECCC
TPHMLVMTATPIPRTLVLAAFGDMDVSKLTEKPAGRKPIQTVTIPTERIGDIVERLRAAL
CCEEEEEECCCCCCEEEEEECCCCCHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHH
KDGKKAYWICPLVEETEESDLMSAEERHAVLSQMLGANIGLIHGRMNGPEKDAAMLAFKS
HCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEEC
GETRLLVATTVVEVGVDVPDATIMVIEHAERFGLAQLHQLRGRVGRGDEASTCILLYKGP
CCCEEEEEEEEHHHCCCCCCCEEEEEECHHHCCHHHHHHHHCCCCCCCCCCEEEEEEECC
LSENGRARLSILRDSEDGFLIAEEDLKLRGEGELLGTRQSGTPGFRIASLEAHADLLEIA
CCCCCCEEEEEEEECCCCEEEECCCCEEECCCCEEEECCCCCCCEEEEEEHHHHHHHHHH
RKDAAYVIERDPELTGPRGESLRTLLYLHRRDEAIRFLHAG
HCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]