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The map label for this gene is fmt [C]

Identifier: 159184903

GI number: 159184903

Start: 1747392

End: 1748168

Strand: Direct

Name: fmt [C]

Synonym: Atu1763

Alternate gene names: 159184903

Gene position: 1747392-1748168 (Clockwise)

Preceding gene: 159185435

Following gene: 159184904

Centisome position: 61.49

GC content: 60.36

Gene sequence:

>777_bases
ATGACTGACATCAACAATCGGCTTCTCGTGATGACGGCAGGTGGCGCAAACCCCAATGTCATGATCAATGCATTGGCCGC
CCGTTTTCCGGATATCCACGTCTTCATGGAGCAGCCGGAAAGCAAGTCGGCCATTCTCAAACGCCGGGCACGGCGGCTCG
GCTGGTTTGCCGCCGCGGGCCAGATGGCGACAATGGTTGCATCCCGCCTTGGCAAACGCTTCACGGCCCGAAGAAGCCAT
GAAATCATCGCCGAACACGGTCTGTCTGCCGATCTCCACCACGGTCTTCCCATCACGCAATTTACCTCACTGAACGACGA
AGAATGCCAGAAGGCCGCCAATCTGCTGAAACCGGCGGTAATCTTCACCATTTCCTGCCGCCTGTTAACGCCGGCGACGC
TGCGGACCCTGCAATGTCCGGTCATCAATTTCCACGCCGGTATCAATCCCGCCTATCGCGGCCAGATGGGCGGTTATTGG
GCGCTGGTGGAAAAGGACCGCGGCAATTTCGGCGCGACCGTGCATCTGGTCGACAAGGGCGTGGATACCGGCGCCACGCT
TTATGAAAAACGGCTGAAACCCTCGCCCTCCGACACCATCGCCACCTATCCGCTGCTTTTGACCGCCGCCTCGGTGGATA
TCGCCGTCAGCGCCATCGAGGACGCCCTGTCCGGCAGCCTCGCGCCGCAGCCGCCCTCGCCCGGAAAATCGGTGCTGCGC
TTTCCGCCACCGATCTGGACATGGTTGTGGAACGGCCTGACGAAACGGATCTGGTAA

Upstream 100 bases:

>100_bases
GCATTTCAAAAAATCCTGTCGATGAAAATTAACAGGGTTTTGAAGTTCCCAAGAGAAACTAGGTGCCAGGATCGTGGCTT
AGGAAATTTCCGTGGGTGAT

Downstream 100 bases:

>100_bases
AACCGCGCGCAAGCACCTGCAACCAAGCCTCGTCGCAGATGCAAGCCTGTCTTGCCGCAACAGACACAGACTTCGGCGGA
AAAACGGTGCATGGTAACAA

Product: hypothetical protein

Products: tetrahydrofolate; N-formylmethionyl-tRNA [C]

Alternate protein names: Formyl Transferase Domain Protein; Formyl Transferase-Like Protein; Formyltransferase Protein

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MTDINNRLLVMTAGGANPNVMINALAARFPDIHVFMEQPESKSAILKRRARRLGWFAAAGQMATMVASRLGKRFTARRSH
EIIAEHGLSADLHHGLPITQFTSLNDEECQKAANLLKPAVIFTISCRLLTPATLRTLQCPVINFHAGINPAYRGQMGGYW
ALVEKDRGNFGATVHLVDKGVDTGATLYEKRLKPSPSDTIATYPLLLTAASVDIAVSAIEDALSGSLAPQPPSPGKSVLR
FPPPIWTWLWNGLTKRIW

Sequences:

>Translated_258_residues
MTDINNRLLVMTAGGANPNVMINALAARFPDIHVFMEQPESKSAILKRRARRLGWFAAAGQMATMVASRLGKRFTARRSH
EIIAEHGLSADLHHGLPITQFTSLNDEECQKAANLLKPAVIFTISCRLLTPATLRTLQCPVINFHAGINPAYRGQMGGYW
ALVEKDRGNFGATVHLVDKGVDTGATLYEKRLKPSPSDTIATYPLLLTAASVDIAVSAIEDALSGSLAPQPPSPGKSVLR
FPPPIWTWLWNGLTKRIW
>Mature_257_residues
TDINNRLLVMTAGGANPNVMINALAARFPDIHVFMEQPESKSAILKRRARRLGWFAAAGQMATMVASRLGKRFTARRSHE
IIAEHGLSADLHHGLPITQFTSLNDEECQKAANLLKPAVIFTISCRLLTPATLRTLQCPVINFHAGINPAYRGQMGGYWA
LVEKDRGNFGATVHLVDKGVDTGATLYEKRLKPSPSDTIATYPLLLTAASVDIAVSAIEDALSGSLAPQPPSPGKSVLRF
PPPIWTWLWNGLTKRIW

Specific function: Modifies The Free Amino Group Of The Aminoacyl Moiety Of Methionyl-Trna(Fmet). The Formyl Group Appears To Play A Dual Role In The Initiator Identity Of N-Formylmethionyl-Trna By: (I) Promoting Its Recognition By If2 And (II) Impairing Its Binding To Eftu

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.2.9 [C]

Molecular weight: Translated: 28203; Mature: 28072

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDINNRLLVMTAGGANPNVMINALAARFPDIHVFMEQPESKSAILKRRARRLGWFAAAG
CCCCCCEEEEEEECCCCCCCEEEEHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
QMATMVASRLGKRFTARRSHEIIAEHGLSADLHHGLPITQFTSLNDEECQKAANLLKPAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHCCCCCHHHHHHHHHHHCCEE
IFTISCRLLTPATLRTLQCPVINFHAGINPAYRGQMGGYWALVEKDRGNFGATVHLVDKG
EEEEEEEEECCHHHHHEECCEEEEECCCCHHHCCCCCCEEEEEEECCCCCCCEEEEEECC
VDTGATLYEKRLKPSPSDTIATYPLLLTAASVDIAVSAIEDALSGSLAPQPPSPGKSVLR
CCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
FPPPIWTWLWNGLTKRIW
CCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDINNRLLVMTAGGANPNVMINALAARFPDIHVFMEQPESKSAILKRRARRLGWFAAAG
CCCCCEEEEEEECCCCCCCEEEEHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
QMATMVASRLGKRFTARRSHEIIAEHGLSADLHHGLPITQFTSLNDEECQKAANLLKPAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHCCCCCHHHHHHHHHHHCCEE
IFTISCRLLTPATLRTLQCPVINFHAGINPAYRGQMGGYWALVEKDRGNFGATVHLVDKG
EEEEEEEEECCHHHHHEECCEEEEECCCCHHHCCCCCCEEEEEEECCCCCCCEEEEEECC
VDTGATLYEKRLKPSPSDTIATYPLLLTAASVDIAVSAIEDALSGSLAPQPPSPGKSVLR
CCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
FPPPIWTWLWNGLTKRIW
CCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Ca2+; K+; Mg2+; Na+; NH4+ [C]

Kcat value (1/min): 1200 [C]

Specific activity: 1.14

Km value (mM): 0.013 {10-formyltetrahydrofolate}} 0.0013 {phenylalanyl-tRNAfMet}} 0.0006 {methionyl-tRNAfMet}} 0.00035 {methionyl-tRNAfMet}} 0.0014 {valyl-tRNAfMet}} [C]

Substrates: Formyltetrahydrofolate; L-methionyl-tRNA; H2O [C]

Specific reaction: Formyltetrahydrofolate + L-methionyl-tRNA + H2O =tetrahydrofolate + N-formylmethionyl-tRNA [C]

General reaction: Formyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA