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The map label for this gene is tsf

Identifier: 159184737

GI number: 159184737

Start: 1369132

End: 1370058

Strand: Direct

Name: tsf

Synonym: Atu1375

Alternate gene names: 159184737

Gene position: 1369132-1370058 (Clockwise)

Preceding gene: 159184736

Following gene: 159184738

Centisome position: 48.18

GC content: 59.98

Gene sequence:

>927_bases
ATGACCGAAATCACAGCCGCAATGGTGAAGGAACTGCGCGAGAAGTCTGGCGCAGGCATGATGGACTGCAAGAAGGCTCT
TGCTGAAACCAATGGCGACATGGAAGCGGCAATCGACTGGCTGCGCGCCAAGGGCATCGCAAAGGCCGACAAGAAGTCCG
GCCGCACGGCTGCCGAAGGTCTGATCGGCGTTGCCACCATGGGTCACAAGGCTGTTGTTGTCGAACTCAACTCCGAAACC
GACTTCGTTGCCCGTAACGACGCGTTCCAGGACCTCATCCGCGGTATTGCGCAGGTTGCTCTGACAACCGACGGCACCGT
TGACGCTGTTTCCGCTGCGACCTATCCGGCAACCGGCAAGTCTGTTGCCGACAGCATCAAGGACGCGATTGCGACCATCG
GCGAAAACATGACGCTGCGCCGCTCGGCTGCACTCGAAGTGCCGCACGGTGTTGTTGCGACCTACGTCCACAACGCTGCC
GGCGACGGCATCGGCAAGCTCGGCGTTCTGGTTGCCCTGAAGTCGGAAGGCGACAAGGCCGTTCTGAACTCCATCGGCCG
TCAGGTTGCCATGCACATCGCTGCGACCAACCCGCTCGCCATCCGCGCTGAAGAAGTCGACGCCGCTGTTGCTGAACGCG
AGCGCAACGTCTTCATCGAACAGGCCCGCGAATCCGGCAAGCCGGAAGCCATCATCGAAAAGATGGTTGATGGCCGTATG
CGCAAGTTCTTCGAAGAAGTCGCCCTTCTGTCGCAGGCTTTCGTTATCAACCCTGACATCACTGTCGGCGCTGCCATCAA
GGAAGTCGAAAAGGAAGCCGGCGCTTCCATCGAAGTGACGGGCATGGTTCGCCTGCTGCTCGGCGAAGGCGTCGAAAAGG
AAGAAAGCGATTTCGCGGCAGAAGTCGCAGCCGTCGCCAAGGGCTGA

Upstream 100 bases:

>100_bases
TCCGGGTTTCAAAGGGTGTGCGGCCGGGTACAGTCATCACCCAGAACTTCGGCACGGCAAATTCCGCCGACTGACCGATC
GAACCGATAAGAGGCAAACA

Downstream 100 bases:

>100_bases
TTATATTTACCCAATCTTGGGAAAACGGGAGGGCATCGCGTGACAACGCGGTGCCCTTCGTGTATCCGCGTTTCGGTTAC
ATTTCCGAGGAGTCATGATG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTEITAAMVKELREKSGAGMMDCKKALAETNGDMEAAIDWLRAKGIAKADKKSGRTAAEGLIGVATMGHKAVVVELNSET
DFVARNDAFQDLIRGIAQVALTTDGTVDAVSAATYPATGKSVADSIKDAIATIGENMTLRRSAALEVPHGVVATYVHNAA
GDGIGKLGVLVALKSEGDKAVLNSIGRQVAMHIAATNPLAIRAEEVDAAVAERERNVFIEQARESGKPEAIIEKMVDGRM
RKFFEEVALLSQAFVINPDITVGAAIKEVEKEAGASIEVTGMVRLLLGEGVEKEESDFAAEVAAVAKG

Sequences:

>Translated_308_residues
MTEITAAMVKELREKSGAGMMDCKKALAETNGDMEAAIDWLRAKGIAKADKKSGRTAAEGLIGVATMGHKAVVVELNSET
DFVARNDAFQDLIRGIAQVALTTDGTVDAVSAATYPATGKSVADSIKDAIATIGENMTLRRSAALEVPHGVVATYVHNAA
GDGIGKLGVLVALKSEGDKAVLNSIGRQVAMHIAATNPLAIRAEEVDAAVAERERNVFIEQARESGKPEAIIEKMVDGRM
RKFFEEVALLSQAFVINPDITVGAAIKEVEKEAGASIEVTGMVRLLLGEGVEKEESDFAAEVAAVAKG
>Mature_307_residues
TEITAAMVKELREKSGAGMMDCKKALAETNGDMEAAIDWLRAKGIAKADKKSGRTAAEGLIGVATMGHKAVVVELNSETD
FVARNDAFQDLIRGIAQVALTTDGTVDAVSAATYPATGKSVADSIKDAIATIGENMTLRRSAALEVPHGVVATYVHNAAG
DGIGKLGVLVALKSEGDKAVLNSIGRQVAMHIAATNPLAIRAEEVDAAVAERERNVFIEQARESGKPEAIIEKMVDGRMR
KFFEEVALLSQAFVINPDITVGAAIKEVEKEAGASIEVTGMVRLLLGEGVEKEESDFAAEVAAVAKG

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=287, Percent_Identity=30.6620209059233, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI291084500, Length=311, Percent_Identity=29.2604501607717, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI291084502, Length=170, Percent_Identity=32.3529411764706, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI291084498, Length=100, Percent_Identity=45, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1786366, Length=307, Percent_Identity=44.9511400651466, Blast_Score=228, Evalue=5e-61,
Organism=Caenorhabditis elegans, GI17561440, Length=281, Percent_Identity=30.9608540925267, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19921466, Length=308, Percent_Identity=29.2207792207792, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_AGRT5 (Q8UFM2)

Other databases:

- EMBL:   AE007869
- PIR:   AG2745
- PIR:   F97526
- RefSeq:   NP_354382.2
- ProteinModelPortal:   Q8UFM2
- SMR:   Q8UFM2
- STRING:   Q8UFM2
- GeneID:   1133413
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1375
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   Q8UFM2
- ProtClustDB:   PRK09377
- BioCyc:   ATUM176299-1:ATU1375-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 32318; Mature: 32187

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEITAAMVKELREKSGAGMMDCKKALAETNGDMEAAIDWLRAKGIAKADKKSGRTAAEG
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHCCCHHHHH
LIGVATMGHKAVVVELNSETDFVARNDAFQDLIRGIAQVALTTDGTVDAVSAATYPATGK
HHHHEECCCEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCH
SVADSIKDAIATIGENMTLRRSAALEVPHGVVATYVHNAAGDGIGKLGVLVALKSEGDKA
HHHHHHHHHHHHHCCCCEEEHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCHH
VLNSIGRQVAMHIAATNPLAIRAEEVDAAVAERERNVFIEQARESGKPEAIIEKMVDGRM
HHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RKFFEEVALLSQAFVINPDITVGAAIKEVEKEAGASIEVTGMVRLLLGEGVEKEESDFAA
HHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCCCHHHHHHH
EVAAVAKG
HHHHHCCC
>Mature Secondary Structure 
TEITAAMVKELREKSGAGMMDCKKALAETNGDMEAAIDWLRAKGIAKADKKSGRTAAEG
CCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHCCCHHHHH
LIGVATMGHKAVVVELNSETDFVARNDAFQDLIRGIAQVALTTDGTVDAVSAATYPATGK
HHHHEECCCEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCH
SVADSIKDAIATIGENMTLRRSAALEVPHGVVATYVHNAAGDGIGKLGVLVALKSEGDKA
HHHHHHHHHHHHHCCCCEEEHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCHH
VLNSIGRQVAMHIAATNPLAIRAEEVDAAVAERERNVFIEQARESGKPEAIIEKMVDGRM
HHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RKFFEEVALLSQAFVINPDITVGAAIKEVEKEAGASIEVTGMVRLLLGEGVEKEESDFAA
HHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCCCHHHHHHH
EVAAVAKG
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194