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The map label for this gene is era

Identifier: 159184589

GI number: 159184589

Start: 1028238

End: 1029179

Strand: Direct

Name: era

Synonym: Atu1036

Alternate gene names: 159184589

Gene position: 1028238-1029179 (Clockwise)

Preceding gene: 159184588

Following gene: 15888379

Centisome position: 36.19

GC content: 59.98

Gene sequence:

>942_bases
ATGACCGATCACGAAAATCCCGCCGTAACGGGCGAAGACAATGCCCTTCCGACCCGTTCCGGTTTCGTCGCCCTCATCGG
CCCGACCAATGCTGGAAAATCGACGCTGGTGAACCGGCTGGTGGGCGCCAAAGTCTCGATCGTCAGCCACAAGGTGCAGA
CGACGCGCGCGGTCATGCGCGGCATCGCCATTCACAAGAATGCGCAGATCGTTTTCATGGACACGCCCGGCATCTTCAAG
CCGCGCCGCAGGCTCGACCGCGCCATGGTCACTTCGGCTTGGGGTGGTGCGAAGGATGCGGATCTCATTCTGCTGCTGAT
CGACAGCGAGCGCGGCCTGAAGGGTGATGCCGAGGCCATTCTCGAAGGGCTGAAGGATGTTCCGCAGAAGAAAATCCTGT
GCCTCAACAAGATCGACCAGGTGAAGCGCGAAGACCTTCTGAAGCTCGCCGCCGCCGCCAACGAAAAGGTCGCGTTTGAT
CGCACCTTCATGATTTCCGCCACCAACGGTTCGGGCTGCGAAGACCTGATGGATTATCTGGTGGAGACCCTGCCGGAAGG
CCCGTGGTATTATCCGGAAGACCAGATTTCCGATCTGCCGATGCGCCAGCTCGCCGCCGAAATCACCCGCGAAAAACTCT
TCCTGCGCCTGCATCAGGAACTTCCCTATGCCTCGCATGTCGAGACGGAAAAGTGGGAAGAGCGCAAGGATGGCTCCGTG
CGCATCGAGCAGGTGATCTATGTCGAGCGCGACAGCCAGAAGAAGATCGCGCTCGGCAAGAACGGCGATGCGATCAAGGC
GATCTCCACCGCCTCGCGCAAGGAGCTGTCAGAAATCCTCGAGCAGCCGGTGCATCTCTTCCTGTTCGTGAAGGTCCGCG
AGAACTGGGGCGACGACCCCGAGCGCTTCCGTGAAATGGGTCTGGAATTCCCGCGGGGTTAA

Upstream 100 bases:

>100_bases
GCCCCACCGGAAACTGAGCACCCGACGACAGGGTGCTGCAACCGAGCGCATGGCGGACCCTTTGGCCGCATGTTGAATAC
CTCTGACCTTGATGGATATC

Downstream 100 bases:

>100_bases
CGCACGCTCGGTTTTCCCCGGCACCTCATTCCTGTGACAAGCGCAGGAATGAGGTGGGAATATCTTCGTCTACCACCGGG
AACCGAACACGTTCGGGCCG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTDHENPAVTGEDNALPTRSGFVALIGPTNAGKSTLVNRLVGAKVSIVSHKVQTTRAVMRGIAIHKNAQIVFMDTPGIFK
PRRRLDRAMVTSAWGGAKDADLILLLIDSERGLKGDAEAILEGLKDVPQKKILCLNKIDQVKREDLLKLAAAANEKVAFD
RTFMISATNGSGCEDLMDYLVETLPEGPWYYPEDQISDLPMRQLAAEITREKLFLRLHQELPYASHVETEKWEERKDGSV
RIEQVIYVERDSQKKIALGKNGDAIKAISTASRKELSEILEQPVHLFLFVKVRENWGDDPERFREMGLEFPRG

Sequences:

>Translated_313_residues
MTDHENPAVTGEDNALPTRSGFVALIGPTNAGKSTLVNRLVGAKVSIVSHKVQTTRAVMRGIAIHKNAQIVFMDTPGIFK
PRRRLDRAMVTSAWGGAKDADLILLLIDSERGLKGDAEAILEGLKDVPQKKILCLNKIDQVKREDLLKLAAAANEKVAFD
RTFMISATNGSGCEDLMDYLVETLPEGPWYYPEDQISDLPMRQLAAEITREKLFLRLHQELPYASHVETEKWEERKDGSV
RIEQVIYVERDSQKKIALGKNGDAIKAISTASRKELSEILEQPVHLFLFVKVRENWGDDPERFREMGLEFPRG
>Mature_312_residues
TDHENPAVTGEDNALPTRSGFVALIGPTNAGKSTLVNRLVGAKVSIVSHKVQTTRAVMRGIAIHKNAQIVFMDTPGIFKP
RRRLDRAMVTSAWGGAKDADLILLLIDSERGLKGDAEAILEGLKDVPQKKILCLNKIDQVKREDLLKLAAAANEKVAFDR
TFMISATNGSGCEDLMDYLVETLPEGPWYYPEDQISDLPMRQLAAEITREKLFLRLHQELPYASHVETEKWEERKDGSVR
IEQVIYVERDSQKKIALGKNGDAIKAISTASRKELSEILEQPVHLFLFVKVRENWGDDPERFREMGLEFPRG

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain

Homologues:

Organism=Homo sapiens, GI24307899, Length=320, Percent_Identity=29.6875, Blast_Score=121, Evalue=7e-28,
Organism=Escherichia coli, GI1788919, Length=292, Percent_Identity=37.3287671232877, Blast_Score=191, Evalue=5e-50,
Organism=Drosophila melanogaster, GI24646434, Length=314, Percent_Identity=27.0700636942675, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERA_AGRT5 (Q8UGK1)

Other databases:

- EMBL:   AE007869
- PIR:   AC2704
- PIR:   C97486
- RefSeq:   NP_354059.2
- ProteinModelPortal:   Q8UGK1
- SMR:   Q8UGK1
- STRING:   Q8UGK1
- GeneID:   1133074
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1036
- eggNOG:   COG1159
- HOGENOM:   HBG561652
- OMA:   ITREQLF
- PhylomeDB:   Q8UGK1
- ProtClustDB:   PRK00089
- BioCyc:   ATUM176299-1:ATU1036-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00367
- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- TIGRFAMs:   TIGR00436
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1; SSF54814 KH_prok

EC number: NA

Molecular weight: Translated: 35105; Mature: 34974

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50823 KH_TYPE_2; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDHENPAVTGEDNALPTRSGFVALIGPTNAGKSTLVNRLVGAKVSIVSHKVQTTRAVMR
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GIAIHKNAQIVFMDTPGIFKPRRRLDRAMVTSAWGGAKDADLILLLIDSERGLKGDAEAI
HHHEECCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHH
LEGLKDVPQKKILCLNKIDQVKREDLLKLAAAANEKVAFDRTFMISATNGSGCEDLMDYL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECEEEEEEECCCCCHHHHHHHH
VETLPEGPWYYPEDQISDLPMRQLAAEITREKLFLRLHQELPYASHVETEKWEERKDGSV
HHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHCCCCCE
RIEQVIYVERDSQKKIALGKNGDAIKAISTASRKELSEILEQPVHLFLFVKVRENWGDDP
EEEEEEEEECCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCH
ERFREMGLEFPRG
HHHHHHCCCCCCC
>Mature Secondary Structure 
TDHENPAVTGEDNALPTRSGFVALIGPTNAGKSTLVNRLVGAKVSIVSHKVQTTRAVMR
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GIAIHKNAQIVFMDTPGIFKPRRRLDRAMVTSAWGGAKDADLILLLIDSERGLKGDAEAI
HHHEECCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHH
LEGLKDVPQKKILCLNKIDQVKREDLLKLAAAANEKVAFDRTFMISATNGSGCEDLMDYL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECEEEEEEECCCCCHHHHHHHH
VETLPEGPWYYPEDQISDLPMRQLAAEITREKLFLRLHQELPYASHVETEKWEERKDGSV
HHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHCCCCCE
RIEQVIYVERDSQKKIALGKNGDAIKAISTASRKELSEILEQPVHLFLFVKVRENWGDDP
EEEEEEEEECCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCH
ERFREMGLEFPRG
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194