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The map label for this gene is gmr [H]

Identifier: 159184564

GI number: 159184564

Start: 984866

End: 985771

Strand: Direct

Name: gmr [H]

Synonym: Atu0989

Alternate gene names: 159184564

Gene position: 984866-985771 (Clockwise)

Preceding gene: 159184562

Following gene: 15888334

Centisome position: 34.66

GC content: 59.38

Gene sequence:

>906_bases
ATGGACGTTTTCATCCACCAGCTCATGACACTCATGGAGGCGTCGCAACAAGGCTACGCGCTATTTGATGGTAATGATGA
GCTTCGTTTCGCCAACAGCGCATTCCGCGCCGCGCTCGGCATAGGACGCCATGAATTCCCCAGCTGGGTGGATATGATGC
GCAGCGGCTATCGTACCACCACCGGCACGAGCATAGAGACTTCGGATTTCGAATTGTGGCTGCGCTCGGCAAAGACGCGG
CGTGGCAAATTGCCGTTTCGCACCATCGAAACCAGCCTGAAGGACGGTCGGTGGATGCTGACGACCGAAACGACGTTGCC
GGGCGGCTGGATGCTGTGCGTCATCACCGACGTGTCTGAACTCGGCATCGAATTGCGCGATCTGCGCCAGGAGCGGGACC
GGGCGCTCAAATCCGCGCTGAGTGACGAACTGACGGGGCTTGGAAACCGCCGTTATGCGATGGATACGCTCAACCATCTG
CTGGGACCGAACAAGGCGCAGGCGCTCGCCGTCATCATCATGGATATCGACCACTTCAAGAGTGTCAACGACCGCTTCGG
CCATGCCTATGGCGATCTCGTGCTGAAAGATTTTGCGGCCCGGCTCTCCGCCACCGCCGGCCGTGATGATCTTCTTGGCA
GGATCGGCGGAGAAGAGTTTCTGCTGGTCCTCAGCGGGTCACGGATGCACAGCGCCGATAGTCTGATGCGGCAGCTTTTG
TCATCGCTGGCGCAGGCTTCGCCTCTTGGGGACAGGCCGGATTTCCGTTACAGTTGCTCTGCCGGCATCGCCTATGCCAA
TCCCGGCGAAAGCGCCAGCGAGGTGCTGCGCCACGCCGATACCGCGCTTTATGAAGCCAAGAATACGGGGCGAAACCGTT
ACGTGATCTACGCAACGGTTCCTTGA

Upstream 100 bases:

>100_bases
CTGTCGTTTTCGTAGCCGTGGAAATTCGATGCCCTACAAGATCAGCCAATACGTATTGGACGACGCGACGCCTGACGACA
GCGGTATCGTTCAGGGTGAT

Downstream 100 bases:

>100_bases
TCGGCCTTGAGGCGGAAGCCTTTAATTCGACTTCGCGGCGCCGCCGTCTACCCGCAGCATCGTGCCGGTAATATAGCTCG
CCGGCACCGAGCAGAGGAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MDVFIHQLMTLMEASQQGYALFDGNDELRFANSAFRAALGIGRHEFPSWVDMMRSGYRTTTGTSIETSDFELWLRSAKTR
RGKLPFRTIETSLKDGRWMLTTETTLPGGWMLCVITDVSELGIELRDLRQERDRALKSALSDELTGLGNRRYAMDTLNHL
LGPNKAQALAVIIMDIDHFKSVNDRFGHAYGDLVLKDFAARLSATAGRDDLLGRIGGEEFLLVLSGSRMHSADSLMRQLL
SSLAQASPLGDRPDFRYSCSAGIAYANPGESASEVLRHADTALYEAKNTGRNRYVIYATVP

Sequences:

>Translated_301_residues
MDVFIHQLMTLMEASQQGYALFDGNDELRFANSAFRAALGIGRHEFPSWVDMMRSGYRTTTGTSIETSDFELWLRSAKTR
RGKLPFRTIETSLKDGRWMLTTETTLPGGWMLCVITDVSELGIELRDLRQERDRALKSALSDELTGLGNRRYAMDTLNHL
LGPNKAQALAVIIMDIDHFKSVNDRFGHAYGDLVLKDFAARLSATAGRDDLLGRIGGEEFLLVLSGSRMHSADSLMRQLL
SSLAQASPLGDRPDFRYSCSAGIAYANPGESASEVLRHADTALYEAKNTGRNRYVIYATVP
>Mature_301_residues
MDVFIHQLMTLMEASQQGYALFDGNDELRFANSAFRAALGIGRHEFPSWVDMMRSGYRTTTGTSIETSDFELWLRSAKTR
RGKLPFRTIETSLKDGRWMLTTETTLPGGWMLCVITDVSELGIELRDLRQERDRALKSALSDELTGLGNRRYAMDTLNHL
LGPNKAQALAVIIMDIDHFKSVNDRFGHAYGDLVLKDFAARLSATAGRDDLLGRIGGEEFLLVLSGSRMHSADSLMRQLL
SSLAQASPLGDRPDFRYSCSAGIAYANPGESASEVLRHADTALYEAKNTGRNRYVIYATVP

Specific function: Part of a 2 protein system that seems to be dedicated to transcription of csgD. This protein decreases csgD transcription and thus decreases expression of adhesive curli fimbriae genes csgEFG, csgBAC/ymaD and adrA (yaic). Activity of this protein is antag

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=230, Percent_Identity=31.7391304347826, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI87081881, Length=189, Percent_Identity=37.5661375661376, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1787262, Length=160, Percent_Identity=36.25, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786584, Length=174, Percent_Identity=34.4827586206897, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1788381, Length=213, Percent_Identity=32.8638497652582, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787816, Length=152, Percent_Identity=32.8947368421053, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87081977, Length=166, Percent_Identity=31.9277108433735, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082007, Length=160, Percent_Identity=36.25, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788085, Length=177, Percent_Identity=30.5084745762712, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788956, Length=173, Percent_Identity=34.1040462427746, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI145693134, Length=195, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787802, Length=137, Percent_Identity=32.8467153284672, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787056, Length=155, Percent_Identity=29.6774193548387, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF00989 PAS [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 33496; Mature: 33496

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVFIHQLMTLMEASQQGYALFDGNDELRFANSAFRAALGIGRHEFPSWVDMMRSGYRTT
CHHHHHHHHHHHHHCCCCCEEECCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCC
TGTSIETSDFELWLRSAKTRRGKLPFRTIETSLKDGRWMLTTETTLPGGWMLCVITDVSE
CCCCEECHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECHHH
LGIELRDLRQERDRALKSALSDELTGLGNRRYAMDTLNHLLGPNKAQALAVIIMDIDHFK
HCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHEEEEEEEEHHHHH
SVNDRFGHAYGDLVLKDFAARLSATAGRDDLLGRIGGEEFLLVLSGSRMHSADSLMRQLL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHH
SSLAQASPLGDRPDFRYSCSAGIAYANPGESASEVLRHADTALYEAKNTGRNRYVIYATV
HHHHHCCCCCCCCCCEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
P
C
>Mature Secondary Structure
MDVFIHQLMTLMEASQQGYALFDGNDELRFANSAFRAALGIGRHEFPSWVDMMRSGYRTT
CHHHHHHHHHHHHHCCCCCEEECCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCC
TGTSIETSDFELWLRSAKTRRGKLPFRTIETSLKDGRWMLTTETTLPGGWMLCVITDVSE
CCCCEECHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECHHH
LGIELRDLRQERDRALKSALSDELTGLGNRRYAMDTLNHLLGPNKAQALAVIIMDIDHFK
HCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHEEEEEEEEHHHHH
SVNDRFGHAYGDLVLKDFAARLSATAGRDDLLGRIGGEEFLLVLSGSRMHSADSLMRQLL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHH
SSLAQASPLGDRPDFRYSCSAGIAYANPGESASEVLRHADTALYEAKNTGRNRYVIYATV
HHHHHCCCCCCCCCCEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]