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The map label for this gene is dapA [H]

Identifier: 159184522

GI number: 159184522

Start: 890200

End: 891108

Strand: Direct

Name: dapA [H]

Synonym: Atu0899

Alternate gene names: 159184522

Gene position: 890200-891108 (Clockwise)

Preceding gene: 15888237

Following gene: 15888239

Centisome position: 31.33

GC content: 65.35

Gene sequence:

>909_bases
ATGGCGACACGATTCAAGGGACTTTCGGCTTTTCCGATCACGCCGGCTGACGAGGCCGGGCGAGTCGATATTGAGGCCTT
CTCCGCCCTGATCGCGCGGCTGGACGCGGCGGAGGTCGATTCCGTCGGCATCCTCGGCAGCACCGGCATCTATATGTATC
TCACGCGTGAGGAGAGACGCCGCGCCATCGAGGCAGCCGCCACGATCCTCAGGGGCAGGCGCACGCTGATGGCAGGCATC
GGCGCGTTGCGCACCGATGAAGCCGTGGCGCTGGCGAAAGACGCTGAAGCAGCCGGTGCGGACGCGCTGCTGCTCGCACC
CGTCTCCTACACGCCGCTGACGCAGGAAGAGGCCTATCACCACTTCGCCGCCGTCGCGGGCGCAACGGCCCTGCCGCTCG
CCATCTACAACAACCCGACGACCACCCGCTTCACCTTCAGCGACGAGCTTCTCGTGCGGCTGGCCTATATCCCGAATATC
CGCGCCATCAAGATGCCGCTGCCGGCCGATGCCGATTATGCCGGCGAGCTTGCACGTCTGCGCCCCAAGCTGTCGGACGA
TTTCGCCATTGGTTACAGTGGTGACTGGGGCTGCACTGACGCCACACTTGCCGGCGGTGACACCTGGTACAGCGTGGTTG
CCGGTCTGCTCCCGGTTCCGGCGTTGCAACTGATGCGGGCGGCTCAGGCCGGCAATGCGGAGGAGGCAAAAAGGCTCGAT
GCGACCTTCCAGCCGCTCTGGGCGCTGTTTAAGGAATTCGGCAGTATCCGCGTGATCTATGCCGCCGCCAACATCCTGTC
GCTGACGGTCAGCGAACCACCCCGGCCGATCCTGCCGCTCACCAGCGCGGAGCGCCAGCGGGTGGAAGAGGCGCTGGAGG
CACTATCCGCGCTAGAAACCGCGCCATAA

Upstream 100 bases:

>100_bases
CGAAATTTTCGGCGTCTTGAGGAAGTTTAGCCCCGCTTTTCTTGCCGCTCCGCCAGTGGCTCTGTAACCCTGCTTGCCGA
TCAAAGCGAGGGAGACGGAC

Downstream 100 bases:

>100_bases
TTCGGGCGCTTTGCGGGCGGATTGCCACGGGAATACACTGCATGACACTGCGGAAAATGAAAATGATGCGTCGCCTCCTG
CTTGCTGCCCTGTTTGCCTC

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MATRFKGLSAFPITPADEAGRVDIEAFSALIARLDAAEVDSVGILGSTGIYMYLTREERRRAIEAAATILRGRRTLMAGI
GALRTDEAVALAKDAEAAGADALLLAPVSYTPLTQEEAYHHFAAVAGATALPLAIYNNPTTTRFTFSDELLVRLAYIPNI
RAIKMPLPADADYAGELARLRPKLSDDFAIGYSGDWGCTDATLAGGDTWYSVVAGLLPVPALQLMRAAQAGNAEEAKRLD
ATFQPLWALFKEFGSIRVIYAAANILSLTVSEPPRPILPLTSAERQRVEEALEALSALETAP

Sequences:

>Translated_302_residues
MATRFKGLSAFPITPADEAGRVDIEAFSALIARLDAAEVDSVGILGSTGIYMYLTREERRRAIEAAATILRGRRTLMAGI
GALRTDEAVALAKDAEAAGADALLLAPVSYTPLTQEEAYHHFAAVAGATALPLAIYNNPTTTRFTFSDELLVRLAYIPNI
RAIKMPLPADADYAGELARLRPKLSDDFAIGYSGDWGCTDATLAGGDTWYSVVAGLLPVPALQLMRAAQAGNAEEAKRLD
ATFQPLWALFKEFGSIRVIYAAANILSLTVSEPPRPILPLTSAERQRVEEALEALSALETAP
>Mature_301_residues
ATRFKGLSAFPITPADEAGRVDIEAFSALIARLDAAEVDSVGILGSTGIYMYLTREERRRAIEAAATILRGRRTLMAGIG
ALRTDEAVALAKDAEAAGADALLLAPVSYTPLTQEEAYHHFAAVAGATALPLAIYNNPTTTRFTFSDELLVRLAYIPNIR
AIKMPLPADADYAGELARLRPKLSDDFAIGYSGDWGCTDATLAGGDTWYSVVAGLLPVPALQLMRAAQAGNAEEAKRLDA
TFQPLWALFKEFGSIRVIYAAANILSLTVSEPPRPILPLTSAERQRVEEALEALSALETAP

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Escherichia coli, GI1788823, Length=294, Percent_Identity=29.9319727891156, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789620, Length=279, Percent_Identity=23.6559139784946, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082415, Length=239, Percent_Identity=28.4518828451883, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786463, Length=239, Percent_Identity=25.9414225941423, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32308; Mature: 32177

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRFKGLSAFPITPADEAGRVDIEAFSALIARLDAAEVDSVGILGSTGIYMYLTREERR
CCCCCCCCEECCCCCCCCCCEECHHHHHHHHHHHCHHCCCCCCEEECCCEEEEEEHHHHH
RAIEAAATILRGRRTLMAGIGALRTDEAVALAKDAEAAGADALLLAPVSYTPLTQEEAYH
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCCCCCCCEEEEECCCCCCCCHHHHHH
HFAAVAGATALPLAIYNNPTTTRFTFSDELLVRLAYIPNIRAIKMPLPADADYAGELARL
HHHHHHCCHHCEEEEECCCCCEEEEECHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHH
RPKLSDDFAIGYSGDWGCTDATLAGGDTWYSVVAGLLPVPALQLMRAAQAGNAEEAKRLD
CCCCCCCEEECCCCCCCCCCCEECCCHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHC
ATFQPLWALFKEFGSIRVIYAAANILSLTVSEPPRPILPLTSAERQRVEEALEALSALET
CHHHHHHHHHHHHCCEEEEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
AP
CC
>Mature Secondary Structure 
ATRFKGLSAFPITPADEAGRVDIEAFSALIARLDAAEVDSVGILGSTGIYMYLTREERR
CCCCCCCEECCCCCCCCCCEECHHHHHHHHHHHCHHCCCCCCEEECCCEEEEEEHHHHH
RAIEAAATILRGRRTLMAGIGALRTDEAVALAKDAEAAGADALLLAPVSYTPLTQEEAYH
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCCCCCCCEEEEECCCCCCCCHHHHHH
HFAAVAGATALPLAIYNNPTTTRFTFSDELLVRLAYIPNIRAIKMPLPADADYAGELARL
HHHHHHCCHHCEEEEECCCCCEEEEECHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHH
RPKLSDDFAIGYSGDWGCTDATLAGGDTWYSVVAGLLPVPALQLMRAAQAGNAEEAKRLD
CCCCCCCEEECCCCCCCCCCCEECCCHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHC
ATFQPLWALFKEFGSIRVIYAAANILSLTVSEPPRPILPLTSAERQRVEEALEALSALET
CHHHHHHHHHHHHCCEEEEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
AP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA