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The map label for this gene is lig [H]

Identifier: 159184490

GI number: 159184490

Start: 838736

End: 839731

Strand: Direct

Name: lig [H]

Synonym: Atu0839

Alternate gene names: 159184490

Gene position: 838736-839731 (Clockwise)

Preceding gene: 159184489

Following gene: 159184491

Centisome position: 29.52

GC content: 61.55

Gene sequence:

>996_bases
TTGTTGAATTCCACGCCGAAGGGGCTTTATTGCCCGGCGGGCGATTTTTACATCGATCCCGTGCGCCCCGTAGCGCGGGC
GCTCATCACCCATGGCCATTCCGATCACGCCCGCGCCGGCCATGGCGCGGTGCTGGCCACGCGCCAGACGCTCGATATCA
TGCGTATTCGTTACGGCGAGGATTTCTGCGGCAGCGAGCAGGCGGTCGGCTTCGGTGAGACGGTGGAGGTGAACGGCGTG
ATCGTCGGTTTCCACCCCGCAGGCCATGTGCTGGGTTCGGCGCAAATCTCCGTGGAAATGAATGGCCTGCGCATCGTCGC
ATCCGGTGATTACAAACGCGGTATCGACCCCACCTGCGCGCCCTTCGAAACAGTGCCGTGTGATGTCTTCATCACAGAAG
CCACTTTCGGCCTGCCGGTGTTTCATCATCCACTGCCGCGTGTGGAAATCGGCAAGCTGCTGACGTCCATCAAACAGTTT
CCCGACCGCACCCATCTCGTCGGCGCTTATTCGCTCGGCAAGGCGCAACGCGTTATCCGGTTATTGCGCGATAATGGTTA
TGCCGATCCCATCTATATTCACGGCGCGCTGGCGCGGCTTTGTGATTATTACGTCTCGCAGGGCATCGATCTTGGTGATC
TCAGGCCCGCGACGCTGGAAAAAAGCAACCCCGCCGCCTTTAAGGGTGCCATCGTTGTTGGTCCGCCCTCGGCCTTTCAG
GAGCGCTGGGCGCGGCGTTTCAACGAGCCGCTGATCGCCTTCGCCTCCGGCTGGATGATGGTGCGGCAGCGCGCGAAGCA
GGGCGGTGTGGAACTACCGCTGGTCATATCTGACCATTGCGACTGGCCGGAACTGCTGGAAACCATCACGGAAATCGGCC
CGCAGGCCGTCTGGGTCACCCATGGCCGCGAGGAGGCGCTGGTACGCTGGTGCGAATTGCAGGGCATTGCCGCCAAGCCG
CTGCATCTCGTCGGTTACGAGGATGAGGGGGACTGA

Upstream 100 bases:

>100_bases
AACACCCCTGCGGGAAATTTAACGCCCGTTCCGCGTTATGCTCGCAGCACTTTACATTCGCGCGGGCGGCCCTATCTCAA
TGAATATGAAGCCGGAACAG

Downstream 100 bases:

>100_bases
AATGAAAGCCTTCGCCACCCTTCTCGACCGCCTTGTCCTCACGCCGTCGCGCAACGGCAAGCTGAAGCTGCTCACCGATT
ATTTCCGCGATACGCCCGAT

Product: hypothetical protein

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MLNSTPKGLYCPAGDFYIDPVRPVARALITHGHSDHARAGHGAVLATRQTLDIMRIRYGEDFCGSEQAVGFGETVEVNGV
IVGFHPAGHVLGSAQISVEMNGLRIVASGDYKRGIDPTCAPFETVPCDVFITEATFGLPVFHHPLPRVEIGKLLTSIKQF
PDRTHLVGAYSLGKAQRVIRLLRDNGYADPIYIHGALARLCDYYVSQGIDLGDLRPATLEKSNPAAFKGAIVVGPPSAFQ
ERWARRFNEPLIAFASGWMMVRQRAKQGGVELPLVISDHCDWPELLETITEIGPQAVWVTHGREEALVRWCELQGIAAKP
LHLVGYEDEGD

Sequences:

>Translated_331_residues
MLNSTPKGLYCPAGDFYIDPVRPVARALITHGHSDHARAGHGAVLATRQTLDIMRIRYGEDFCGSEQAVGFGETVEVNGV
IVGFHPAGHVLGSAQISVEMNGLRIVASGDYKRGIDPTCAPFETVPCDVFITEATFGLPVFHHPLPRVEIGKLLTSIKQF
PDRTHLVGAYSLGKAQRVIRLLRDNGYADPIYIHGALARLCDYYVSQGIDLGDLRPATLEKSNPAAFKGAIVVGPPSAFQ
ERWARRFNEPLIAFASGWMMVRQRAKQGGVELPLVISDHCDWPELLETITEIGPQAVWVTHGREEALVRWCELQGIAAKP
LHLVGYEDEGD
>Mature_331_residues
MLNSTPKGLYCPAGDFYIDPVRPVARALITHGHSDHARAGHGAVLATRQTLDIMRIRYGEDFCGSEQAVGFGETVEVNGV
IVGFHPAGHVLGSAQISVEMNGLRIVASGDYKRGIDPTCAPFETVPCDVFITEATFGLPVFHHPLPRVEIGKLLTSIKQF
PDRTHLVGAYSLGKAQRVIRLLRDNGYADPIYIHGALARLCDYYVSQGIDLGDLRPATLEKSNPAAFKGAIVVGPPSAFQ
ERWARRFNEPLIAFASGWMMVRQRAKQGGVELPLVISDHCDWPELLETITEIGPQAVWVTHGREEALVRWCELQGIAAKP
LHLVGYEDEGD

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323307, Length=193, Percent_Identity=31.6062176165803, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 36256; Mature: 36256

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSTPKGLYCPAGDFYIDPVRPVARALITHGHSDHARAGHGAVLATRQTLDIMRIRYGE
CCCCCCCCEECCCCCEEECCHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHEEHHEECCC
DFCGSEQAVGFGETVEVNGVIVGFHPAGHVLGSAQISVEMNGLRIVASGDYKRGIDPTCA
CCCCCCCCCCCCCEEEECEEEEEECCCCCEECCEEEEEEECCEEEEECCCCCCCCCCCCC
PFETVPCDVFITEATFGLPVFHHPLPRVEIGKLLTSIKQFPDRTHLVGAYSLGKAQRVIR
CCCCCCCEEEEECCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
LLRDNGYADPIYIHGALARLCDYYVSQGIDLGDLRPATLEKSNPAAFKGAIVVGPPSAFQ
HHHCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECEEEECCCHHHH
ERWARRFNEPLIAFASGWMMVRQRAKQGGVELPLVISDHCDWPELLETITEIGPQAVWVT
HHHHHHHCCCEEEHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEE
HGREEALVRWCELQGIAAKPLHLVGYEDEGD
CCCHHHHHHHHHHCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MLNSTPKGLYCPAGDFYIDPVRPVARALITHGHSDHARAGHGAVLATRQTLDIMRIRYGE
CCCCCCCCEECCCCCEEECCHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHEEHHEECCC
DFCGSEQAVGFGETVEVNGVIVGFHPAGHVLGSAQISVEMNGLRIVASGDYKRGIDPTCA
CCCCCCCCCCCCCEEEECEEEEEECCCCCEECCEEEEEEECCEEEEECCCCCCCCCCCCC
PFETVPCDVFITEATFGLPVFHHPLPRVEIGKLLTSIKQFPDRTHLVGAYSLGKAQRVIR
CCCCCCCEEEEECCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
LLRDNGYADPIYIHGALARLCDYYVSQGIDLGDLRPATLEKSNPAAFKGAIVVGPPSAFQ
HHHCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECEEEECCCHHHH
ERWARRFNEPLIAFASGWMMVRQRAKQGGVELPLVISDHCDWPELLETITEIGPQAVWVT
HHHHHHHCCCEEEHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEE
HGREEALVRWCELQGIAAKPLHLVGYEDEGD
CCCHHHHHHHHHHCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA