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The map label for this gene is ccrM [H]

Identifier: 159184467

GI number: 159184467

Start: 790755

End: 791900

Strand: Direct

Name: ccrM [H]

Synonym: Atu0794

Alternate gene names: 159184467

Gene position: 790755-791900 (Clockwise)

Preceding gene: 159184466

Following gene: 15888142

Centisome position: 27.83

GC content: 60.91

Gene sequence:

>1146_bases
ATGGCAGCAGTTTTTCCGCTGGCCGATTTTCGGCGTGCCGGTTTTGATCGTGCGGGCGAGAGTGACGCCTGGAAAGACAG
CATCATCAAAGGTGATTGTGTCGCTGCCTTGGATGCCCTCCCGAGCCAGTCGGTGGATGCGATTTTCGCCGATCCGCCCT
ATAATCTCCAGCTTGGCGGCACGCTGCACCGGCCCGATCAGTCGCTGGTCGATGCCGTTGATGACGAATGGGACCAGTTC
GCCTCCTTCGACGCCTATGACGCCTTCACCCGCGCCTGGCTGCTCGCCTGCCGCCGTGTGCTGAAACCGAACGGCACCAT
CTGGGTCATCGGCTCCTATCACAATATCTTCCGCGTCGGCGCCATGCTCCAGAACCTCGATTTCTGGATCCTCAACGATA
TCGTCTGGCGCAAGACCAACCCCATGCCCAATTTCAAGGGCCGCCGTTTCCAGAACGCCCATGAGACGATGATCTGGGCA
AGTCGCGATCCGAAAGCCAAGAGCTATACCTTCAACTACGACGCGCTGAAGGCCTCCAACGACGATGTCCAGATGCGCTC
GGACTGGCTGTTCCCGATTTGCAGCGGCCATGAGCGGCTGAAAGGCGACGACGGCAAGAAGGTGCATCCCACACAGAAGC
CGGAAGCCCTGCTGGCGCGCATCATCATGGCATCGACCAAGCCGGGCGATATCGTGCTTGACCCGTTCTTCGGTTCCGGC
ACCACGGGTGCCGTTGCAAAACGCCTTGGCCGCCATTTCGTCGGCATCGAGCGCGAACAGGATTATATCGATGCGGCATC
CGCCCGCATCACCGCCGTCGAGCCGCTCGGCAAGGCGGAACTGACCGTCATGACCGGCAAGAAGGCCGAGCCGCGCGTGG
CCTTTAACACGCTGGTGGAAAGCGGCCTCGTCCGCCCCGGCCAGGTGCTGACGGATGCACGACGTCGCTATAGCGCCATT
ATTCGTGCCGATGGTACGCTCGCATCCGGCGGGACCGCCGGCTCCATTCACCGCCTCGGCGCGAAGGTGCAGGGTCTCGA
TGCATGCAATGGATGGACGTTCTGGCATTTCGAGGACGGCGACGCGCTGAAGCCGATCGATGATCTCAGAACCATCATCC
GCAGTGAAATGGCAAAGGCTGAATAG

Upstream 100 bases:

>100_bases
AGCCATTTATTTCGCATTTTCCGTGACTTGTTCAGGCTTTGATAACCATCTTCGGTAACCATAAGCGTCAGTAGAGAGTA
AGCGTATGGAGCGAGTACCA

Downstream 100 bases:

>100_bases
TCGAGAGCCGTAGAGGCTGGAGACGGACGATCCACCGCCCGCCCTTGTCAGAATACGTCTCTGTCCGGTTTAGTACCTTC
AGTCCCGGATAGAGAAACGA

Product: cell cycle regulated site-specific DNA-methyltransferase protein

Products: NA

Alternate protein names: M.SmeI; Adenine-specific methyltransferase SmeIP; M.CcrMI ortholog; Modification methylase SmeIP; M.SmeIP [H]

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MAAVFPLADFRRAGFDRAGESDAWKDSIIKGDCVAALDALPSQSVDAIFADPPYNLQLGGTLHRPDQSLVDAVDDEWDQF
ASFDAYDAFTRAWLLACRRVLKPNGTIWVIGSYHNIFRVGAMLQNLDFWILNDIVWRKTNPMPNFKGRRFQNAHETMIWA
SRDPKAKSYTFNYDALKASNDDVQMRSDWLFPICSGHERLKGDDGKKVHPTQKPEALLARIIMASTKPGDIVLDPFFGSG
TTGAVAKRLGRHFVGIEREQDYIDAASARITAVEPLGKAELTVMTGKKAEPRVAFNTLVESGLVRPGQVLTDARRRYSAI
IRADGTLASGGTAGSIHRLGAKVQGLDACNGWTFWHFEDGDALKPIDDLRTIIRSEMAKAE

Sequences:

>Translated_381_residues
MAAVFPLADFRRAGFDRAGESDAWKDSIIKGDCVAALDALPSQSVDAIFADPPYNLQLGGTLHRPDQSLVDAVDDEWDQF
ASFDAYDAFTRAWLLACRRVLKPNGTIWVIGSYHNIFRVGAMLQNLDFWILNDIVWRKTNPMPNFKGRRFQNAHETMIWA
SRDPKAKSYTFNYDALKASNDDVQMRSDWLFPICSGHERLKGDDGKKVHPTQKPEALLARIIMASTKPGDIVLDPFFGSG
TTGAVAKRLGRHFVGIEREQDYIDAASARITAVEPLGKAELTVMTGKKAEPRVAFNTLVESGLVRPGQVLTDARRRYSAI
IRADGTLASGGTAGSIHRLGAKVQGLDACNGWTFWHFEDGDALKPIDDLRTIIRSEMAKAE
>Mature_380_residues
AAVFPLADFRRAGFDRAGESDAWKDSIIKGDCVAALDALPSQSVDAIFADPPYNLQLGGTLHRPDQSLVDAVDDEWDQFA
SFDAYDAFTRAWLLACRRVLKPNGTIWVIGSYHNIFRVGAMLQNLDFWILNDIVWRKTNPMPNFKGRRFQNAHETMIWAS
RDPKAKSYTFNYDALKASNDDVQMRSDWLFPICSGHERLKGDDGKKVHPTQKPEALLARIIMASTKPGDIVLDPFFGSGT
TGAVAKRLGRHFVGIEREQDYIDAASARITAVEPLGKAELTVMTGKKAEPRVAFNTLVESGLVRPGQVLTDARRRYSAII
RADGTLASGGTAGSIHRLGAKVQGLDACNGWTFWHFEDGDALKPIDDLRTIIRSEMAKAE

Specific function: This methylase recognizes the double-stranded sequence GANTC and causes specific methylation on A-2 on both strands. Ccrm-mediated methylation has important cellular functions. Appears to contribute to the accurate cell-cycle control of DNA replication an

COG id: COG0863

COG function: function code L; DNA modification methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI87082238, Length=278, Percent_Identity=34.1726618705036, Blast_Score=138, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002941
- InterPro:   IPR002052
- InterPro:   IPR001091 [H]

Pfam domain/function: PF01555 N6_N4_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 42216; Mature: 42085

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVFPLADFRRAGFDRAGESDAWKDSIIKGDCVAALDALPSQSVDAIFADPPYNLQLGG
CCCCCCCHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHCCCCCCCEEECCCCCCEEECC
TLHRPDQSLVDAVDDEWDQFASFDAYDAFTRAWLLACRRVLKPNGTIWVIGSYHNIFRVG
EECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHH
AMLQNLDFWILNDIVWRKTNPMPNFKGRRFQNAHETMIWASRDPKAKSYTFNYDALKASN
HHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCHHEECCC
DDVQMRSDWLFPICSGHERLKGDDGKKVHPTQKPEALLARIIMASTKPGDIVLDPFFGSG
CCCEECCCCCCEECCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCC
TTGAVAKRLGRHFVGIEREQDYIDAASARITAVEPLGKAELTVMTGKKAEPRVAFNTLVE
CHHHHHHHHHHHHCCCCCCHHHHHHHCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHH
SGLVRPGQVLTDARRRYSAIIRADGTLASGGTAGSIHRLGAKVQGLDACNGWTFWHFEDG
HCCCCCHHHHHHHHHHHHHHEEECCCEECCCCCCHHHHHCCCCCCCCCCCCEEEEEECCC
DALKPIDDLRTIIRSEMAKAE
CCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AAVFPLADFRRAGFDRAGESDAWKDSIIKGDCVAALDALPSQSVDAIFADPPYNLQLGG
CCCCCCHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHCCCCCCCEEECCCCCCEEECC
TLHRPDQSLVDAVDDEWDQFASFDAYDAFTRAWLLACRRVLKPNGTIWVIGSYHNIFRVG
EECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHH
AMLQNLDFWILNDIVWRKTNPMPNFKGRRFQNAHETMIWASRDPKAKSYTFNYDALKASN
HHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCHHEECCC
DDVQMRSDWLFPICSGHERLKGDDGKKVHPTQKPEALLARIIMASTKPGDIVLDPFFGSG
CCCEECCCCCCEECCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCC
TTGAVAKRLGRHFVGIEREQDYIDAASARITAVEPLGKAELTVMTGKKAEPRVAFNTLVE
CHHHHHHHHHHHHCCCCCCHHHHHHHCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHH
SGLVRPGQVLTDARRRYSAIIRADGTLASGGTAGSIHRLGAKVQGLDACNGWTFWHFEDG
HCCCCCHHHHHHHHHHHHHHEEECCCEECCCCCCHHHHHCCCCCCCCCCCCEEEEEECCC
DALKPIDDLRTIIRSEMAKAE
CCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9294447; 11481430 [H]