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The map label for this gene is dnaJ [H]

Identifier: 159184453

GI number: 159184453

Start: 755159

End: 756274

Strand: Reverse

Name: dnaJ [H]

Synonym: Atu0758

Alternate gene names: 159184453

Gene position: 756274-755159 (Counterclockwise)

Preceding gene: 15888102

Following gene: 15888100

Centisome position: 26.61

GC content: 63.35

Gene sequence:

>1116_bases
ATGCGCGATCCTTATTCTATCCTCGGTGTGAAACGTGACGCCCGTCACGAGGACATCAAGGCCGCCTGGCGCACGAAGGC
GAAAACCGTCCATCCGGACGCCAATCGCGACGATCCCGATGCTTCGGCGCGATTCGCCGAGATCGGACAGGCCTACGATC
TTCTGAAAGATTCGAAAAAGCGCGATCTCTACGATCAGGCCCGACAGGCGGCTGAGAAGAAAAAGCGCGGCGAAACCATC
ATGCAGCAGCGGGAAGCCGCGCGTGAAGCGGCAGAGCGCGCCAAGGCCGCCGAAAAGCTGATGGAAGAACTGGCCCGCGC
GGATGCCCGCAACCGGGCGCAGACCGGCCAGAAAACCGACGCCAAGCCGGAAACCGCCGAAGATATCGTCGAGCGGATCT
TTGGGGCGGACGCCCAGAACGACCCTAAGGTGCAGCAGGCTGCGGAAGCGGCGAAGGCTGCGGCAAGTGCCGCGAAAGGC
GACATACCCGCCGCCGGTGACACTGCCCAGTCTGCCGCCGGCGATGACAGGACCGCGCCCGCCTCACTGGCCGTCAATCT
CTTCAACGCCCTCGTGCGCCGTTTCCGCCCCGCGCAGCCGGCCGCGGAAAAGGTGCCCGATATCACGGCGGAAGCCACCG
TTACGGTCGCCGATCTTCTGGAACACAAGTGGGTCACCCTGCAGCTTGCCGACGAACGCGAAATCCGCTTCCAGCTCGAG
GCCGGCATGGCGGATGGGCATATCGTGCGGCTGAAGGGACAGGGACTGAAGCTTCCCAACCTGGCGCGCGGCGATCTTGC
CGTGACATTGCTGGCCGCCCGGGATGACGCCTTTTCCCTGCGTGGCTTCGACATCCATACGACCTTGCCGATCTCGCTCA
GCGACGCGGTTCTCGGCTGCGAAGCGAAAGTCGCGACACCGCTCGGCGAAGAAAATATCACCATTCCGGCATGGTCCGGC
TCGGACCGCGTGCTGAGGCTTGCCGGCAAAGGCCTTGCCGATGGCAAGGGCGGTTCGGGCGATCTGGTCATAGAATTGCG
CATCGTCCTGCTCGAAAAGCCGGACGAGAAGGTAACCGACCTGATGCGTCACATGCGCGAAGGCCTGTATTTGTGA

Upstream 100 bases:

>100_bases
CGTGCAGGCGAATGATCGCAGGCATCCCTTTTCGGAGGGGTTAGTTTCAGGATTGCGCCATGAGCGGCGGCAGACTGAGC
CAACGTAACTGGTGTTTCGC

Downstream 100 bases:

>100_bases
AAGTTTTGCGAATAGCCGGGACAAAGCACCCTTTGTTACGCTCCCTAACAGTTGATGATCTTTGGCAATCTTGAACAGGA
TTGCAGCCTATGCCATAGGC

Product: DnaJ family molecular chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MRDPYSILGVKRDARHEDIKAAWRTKAKTVHPDANRDDPDASARFAEIGQAYDLLKDSKKRDLYDQARQAAEKKKRGETI
MQQREAAREAAERAKAAEKLMEELARADARNRAQTGQKTDAKPETAEDIVERIFGADAQNDPKVQQAAEAAKAAASAAKG
DIPAAGDTAQSAAGDDRTAPASLAVNLFNALVRRFRPAQPAAEKVPDITAEATVTVADLLEHKWVTLQLADEREIRFQLE
AGMADGHIVRLKGQGLKLPNLARGDLAVTLLAARDDAFSLRGFDIHTTLPISLSDAVLGCEAKVATPLGEENITIPAWSG
SDRVLRLAGKGLADGKGGSGDLVIELRIVLLEKPDEKVTDLMRHMREGLYL

Sequences:

>Translated_371_residues
MRDPYSILGVKRDARHEDIKAAWRTKAKTVHPDANRDDPDASARFAEIGQAYDLLKDSKKRDLYDQARQAAEKKKRGETI
MQQREAAREAAERAKAAEKLMEELARADARNRAQTGQKTDAKPETAEDIVERIFGADAQNDPKVQQAAEAAKAAASAAKG
DIPAAGDTAQSAAGDDRTAPASLAVNLFNALVRRFRPAQPAAEKVPDITAEATVTVADLLEHKWVTLQLADEREIRFQLE
AGMADGHIVRLKGQGLKLPNLARGDLAVTLLAARDDAFSLRGFDIHTTLPISLSDAVLGCEAKVATPLGEENITIPAWSG
SDRVLRLAGKGLADGKGGSGDLVIELRIVLLEKPDEKVTDLMRHMREGLYL
>Mature_371_residues
MRDPYSILGVKRDARHEDIKAAWRTKAKTVHPDANRDDPDASARFAEIGQAYDLLKDSKKRDLYDQARQAAEKKKRGETI
MQQREAAREAAERAKAAEKLMEELARADARNRAQTGQKTDAKPETAEDIVERIFGADAQNDPKVQQAAEAAKAAASAAKG
DIPAAGDTAQSAAGDDRTAPASLAVNLFNALVRRFRPAQPAAEKVPDITAEATVTVADLLEHKWVTLQLADEREIRFQLE
AGMADGHIVRLKGQGLKLPNLARGDLAVTLLAARDDAFSLRGFDIHTTLPISLSDAVLGCEAKVATPLGEENITIPAWSG
SDRVLRLAGKGLADGKGGSGDLVIELRIVLLEKPDEKVTDLMRHMREGLYL

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG2214

COG function: function code O; DnaJ-class molecular chaperone

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI7706495, Length=64, Percent_Identity=53.125, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI205360838, Length=63, Percent_Identity=47.6190476190476, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI205360840, Length=63, Percent_Identity=47.6190476190476, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI6631085, Length=65, Percent_Identity=47.6923076923077, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI201862587, Length=65, Percent_Identity=49.2307692307692, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI201862518, Length=65, Percent_Identity=49.2307692307692, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI56549115, Length=65, Percent_Identity=49.2307692307692, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787235, Length=369, Percent_Identity=26.5582655826558, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1786197, Length=70, Percent_Identity=45.7142857142857, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI212645553, Length=64, Percent_Identity=46.875, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507263, Length=62, Percent_Identity=48.3870967741936, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6320888, Length=62, Percent_Identity=50, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323870, Length=65, Percent_Identity=43.0769230769231, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19920464, Length=74, Percent_Identity=45.945945945946, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45549272, Length=75, Percent_Identity=45.3333333333333, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45552813, Length=71, Percent_Identity=46.4788732394366, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45552811, Length=71, Percent_Identity=46.4788732394366, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 40247; Mature: 40247

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDPYSILGVKRDARHEDIKAAWRTKAKTVHPDANRDDPDASARFAEIGQAYDLLKDSKK
CCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
RDLYDQARQAAEKKKRGETIMQQREAAREAAERAKAAEKLMEELARADARNRAQTGQKTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AKPETAEDIVERIFGADAQNDPKVQQAAEAAKAAASAAKGDIPAAGDTAQSAAGDDRTAP
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCH
ASLAVNLFNALVRRFRPAQPAAEKVPDITAEATVTVADLLEHKWVTLQLADEREIRFQLE
HHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCCCCEEEEEE
AGMADGHIVRLKGQGLKLPNLARGDLAVTLLAARDDAFSLRGFDIHTTLPISLSDAVLGC
CCCCCCEEEEEECCCCCCCCCCCCCEEEEEEEECCCCCEECCEEEEEECCCCCCCHHHCC
EAKVATPLGEENITIPAWSGSDRVLRLAGKGLADGKGGSGDLVIELRIVLLEKPDEKVTD
CCHHCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCHHHHH
LMRHMREGLYL
HHHHHHHCCCC
>Mature Secondary Structure
MRDPYSILGVKRDARHEDIKAAWRTKAKTVHPDANRDDPDASARFAEIGQAYDLLKDSKK
CCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
RDLYDQARQAAEKKKRGETIMQQREAAREAAERAKAAEKLMEELARADARNRAQTGQKTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AKPETAEDIVERIFGADAQNDPKVQQAAEAAKAAASAAKGDIPAAGDTAQSAAGDDRTAP
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCH
ASLAVNLFNALVRRFRPAQPAAEKVPDITAEATVTVADLLEHKWVTLQLADEREIRFQLE
HHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCCCCEEEEEE
AGMADGHIVRLKGQGLKLPNLARGDLAVTLLAARDDAFSLRGFDIHTTLPISLSDAVLGC
CCCCCCEEEEEECCCCCCCCCCCCCEEEEEEEECCCCCEECCEEEEEECCCCCCCHHHCC
EAKVATPLGEENITIPAWSGSDRVLRLAGKGLADGKGGSGDLVIELRIVLLEKPDEKVTD
CCHHCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCHHHHH
LMRHMREGLYL
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA