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The map label for this gene is ywlC [H]

Identifier: 159184438

GI number: 159184438

Start: 724192

End: 725169

Strand: Reverse

Name: ywlC [H]

Synonym: Atu0724

Alternate gene names: 159184438

Gene position: 725169-724192 (Counterclockwise)

Preceding gene: 159184439

Following gene: 15888067

Centisome position: 25.52

GC content: 64.21

Gene sequence:

>978_bases
ATGGCGCGTCATATCAACATTGAAACCGAGCGGGAAACAGCCCTGCAGGCATCCGTGGCCGAGCTTGCGGACGGCAGGCC
CATCGCGCTGCCGACGGAAACCGTCTATGGCCTTGCCGCCGACGCCACCAATCCCGCTGCCATCACCCGTATTTACGAGA
CCAAGGGCCGGCCGCAATTCAACCCGCTGATCTGCCATATGGCCGATATCGCCATGGCCGAGCGTTACGCGGTTTTCGAC
CCGATATCGCGGAAACTCGCAGAGGCCTTCTGGCCCGGCCCACTGACATTGGTTCTGCCGCTGAAACCGGAAAGCGACAT
TCATTCGCTGGCGACGGCCGGGCTCGATACCGTCGGCATTCGCGTGCCGCAGGGTTTTGCCAGCGATCTTATCCGCCGGT
TCGGCAAACCGCTCGCCGCCCCCAGCGCCAATAGTTCCGGCAAGATCAGCCCGACAAGTGCGGCCCATGTGGAAGCCGAT
CTCGGGCAGAAGATCAATCTCGTTCTCGATGGCGGTGCCGCCGCCGTGGGTGTCGAATCCACCATCGTCAAGGTGGAGCA
GGATGGCCGGGTGCGGCTGCTTCGCCCCGGCGGCATCGTCACCGAGGAAATCGAGCGCCTAGCCGGCGTCAGGCTCGAAC
GACCGAAAAAAGCCTCCGCCGCCATCGAGGCGCCGGGAATGCTGGCCTCGCATTATGCGCCGGGCGCCACTGTCCGCCTC
GGCGCCACGTCGGTTCTGCCTGATGAAGCGCTGATCCGATTTGGTGGCATCGCCATATCAGGCGAAGAGACCGCGCGCAC
CATTCTCGACCTCAGCCCTTCCGGCGATCTTGCCGAGGCCGCCGCCAACCTCTTCGATTACCTGAAAGCTGCCGATGCGA
GCGGTGCGGACACCATCGCCATCACCGCAATTCCCACCCATGGTCTTGGAGAGGCGATCAACGACCGCCTTTCCCGCGCC
GCCGCGCCGCGAGGCTGA

Upstream 100 bases:

>100_bases
CTCGGCGGAGATGCGCAAGATCATCAGGGCGATATAAAGCGCGATAGCACTTTCCATCCCCGCCTGAAATACGCTATTGA
CCGCCCTGAAAGGCAGCATC

Downstream 100 bases:

>100_bases
CGGCACTCAACCCTTTCGCCCATGTTTCAAAAGACAGCGAGACGCCGCCCATGACGCCCATGACCGCCATCCCCTCCTCC
GATATCCTTGACCGCTTCAC

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MARHINIETERETALQASVAELADGRPIALPTETVYGLAADATNPAAITRIYETKGRPQFNPLICHMADIAMAERYAVFD
PISRKLAEAFWPGPLTLVLPLKPESDIHSLATAGLDTVGIRVPQGFASDLIRRFGKPLAAPSANSSGKISPTSAAHVEAD
LGQKINLVLDGGAAAVGVESTIVKVEQDGRVRLLRPGGIVTEEIERLAGVRLERPKKASAAIEAPGMLASHYAPGATVRL
GATSVLPDEALIRFGGIAISGEETARTILDLSPSGDLAEAAANLFDYLKAADASGADTIAITAIPTHGLGEAINDRLSRA
AAPRG

Sequences:

>Translated_325_residues
MARHINIETERETALQASVAELADGRPIALPTETVYGLAADATNPAAITRIYETKGRPQFNPLICHMADIAMAERYAVFD
PISRKLAEAFWPGPLTLVLPLKPESDIHSLATAGLDTVGIRVPQGFASDLIRRFGKPLAAPSANSSGKISPTSAAHVEAD
LGQKINLVLDGGAAAVGVESTIVKVEQDGRVRLLRPGGIVTEEIERLAGVRLERPKKASAAIEAPGMLASHYAPGATVRL
GATSVLPDEALIRFGGIAISGEETARTILDLSPSGDLAEAAANLFDYLKAADASGADTIAITAIPTHGLGEAINDRLSRA
AAPRG
>Mature_324_residues
ARHINIETERETALQASVAELADGRPIALPTETVYGLAADATNPAAITRIYETKGRPQFNPLICHMADIAMAERYAVFDP
ISRKLAEAFWPGPLTLVLPLKPESDIHSLATAGLDTVGIRVPQGFASDLIRRFGKPLAAPSANSSGKISPTSAAHVEADL
GQKINLVLDGGAAAVGVESTIVKVEQDGRVRLLRPGGIVTEEIERLAGVRLERPKKASAAIEAPGMLASHYAPGATVRLG
ATSVLPDEALIRFGGIAISGEETARTILDLSPSGDLAEAAANLFDYLKAADASGADTIAITAIPTHGLGEAINDRLSRAA
APRG

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=193, Percent_Identity=35.7512953367876, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI2367210, Length=168, Percent_Identity=30.952380952381, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17537239, Length=209, Percent_Identity=33.4928229665072, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321269, Length=360, Percent_Identity=34.7222222222222, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI78707274, Length=192, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 33911; Mature: 33780

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARHINIETERETALQASVAELADGRPIALPTETVYGLAADATNPAAITRIYETKGRPQF
CCCEECCCCHHHHHHHHHHHHHCCCCCEEECCHHHHEEECCCCCCHHHEEEHHCCCCCCC
NPLICHMADIAMAERYAVFDPISRKLAEAFWPGPLTLVLPLKPESDIHSLATAGLDTVGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCEEE
RVPQGFASDLIRRFGKPLAAPSANSSGKISPTSAAHVEADLGQKINLVLDGGAAAVGVES
ECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHEECCCCCEEEEEEECCCEEEECCE
TIVKVEQDGRVRLLRPGGIVTEEIERLAGVRLERPKKASAAIEAPGMLASHYAPGATVRL
EEEEEECCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHCCCCCCHHHHCCCCCEEEE
GATSVLPDEALIRFGGIAISGEETARTILDLSPSGDLAEAAANLFDYLKAADASGADTIA
CCCCCCCCHHHHHCCCEEECCCHHHHEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
ITAIPTHGLGEAINDRLSRAAAPRG
EEEECCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ARHINIETERETALQASVAELADGRPIALPTETVYGLAADATNPAAITRIYETKGRPQF
CCEECCCCHHHHHHHHHHHHHCCCCCEEECCHHHHEEECCCCCCHHHEEEHHCCCCCCC
NPLICHMADIAMAERYAVFDPISRKLAEAFWPGPLTLVLPLKPESDIHSLATAGLDTVGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCEEE
RVPQGFASDLIRRFGKPLAAPSANSSGKISPTSAAHVEADLGQKINLVLDGGAAAVGVES
ECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHEECCCCCEEEEEEECCCEEEECCE
TIVKVEQDGRVRLLRPGGIVTEEIERLAGVRLERPKKASAAIEAPGMLASHYAPGATVRL
EEEEEECCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHCCCCCCHHHHCCCCCEEEE
GATSVLPDEALIRFGGIAISGEETARTILDLSPSGDLAEAAANLFDYLKAADASGADTIA
CCCCCCCCHHHHHCCCEEECCCHHHHEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
ITAIPTHGLGEAINDRLSRAAAPRG
EEEECCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]