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The map label for this gene is vat [H]

Identifier: 159184434

GI number: 159184434

Start: 719044

End: 719679

Strand: Direct

Name: vat [H]

Synonym: Atu0719

Alternate gene names: 159184434

Gene position: 719044-719679 (Clockwise)

Preceding gene: 159184433

Following gene: 159184437

Centisome position: 25.3

GC content: 51.73

Gene sequence:

>636_bases
ATGGCTCTTCTCGACAGGAATGCGGTTTATCCGATTACTTTACCCGACGGTTGCTTGTATCGGGATACGGTATATCTGAA
GAACGTTGTGGATCATCCACGCATGGAGATAGGTGATTTCACCTATTACACGCATTCTGGAAGACTAGAAGATACAGCGG
TGATCCTTGCGCCTTATCTGGGGCATAGCGTTCGCGAGCGATTGGTGATCGGCAAATTTGTCCAAATCGCGAGAGGCAGT
TACTTCATAACGAGTTCGGCAAACCATCCGATGACTGGCTTCACGACCTATCCGTTTCGCATCTTCAAACCAGAGACCTT
TGGTTACAAAGACCTGCCCGTTAAGGACACGATTGTTGATCACGATGTATGGATTGGCCAGAACGCGGCAATCATGCCGG
GGGTTCGCATAGGCCACGGTGCGATTGTCGCCGCTGCATCGGTTGTTGCTCGCGATGTTCCACCCTACGCAGTCGTCGGA
GGAAACCCGGCATCCATCATCCGAATGCGTTACTCCAGCGAAGTTGTCAGCGAACTACTTCATCTTGCCTGGTGGGACTG
GCCGATCGATAAAATCGAGGCCAATCTAGGGGCGCTTGATAGCGGCGATATTGCCGCGCTCAGATTGGTTCAATAG

Upstream 100 bases:

>100_bases
CTGTGTGACATTAGTCTCGTCGCAACACAGTCGCCCGCAGGGTTTTGCAGAATGCTGCATCTCATCAGCCTAGCTAGCGA
TGCACTTAAAAAGGTTCATC

Downstream 100 bases:

>100_bases
AAACGCAACATTTTTAACTACCCGCTTTGAAAGCGGAGAAGATTAAAAGTCCCGTATTCGCCGCTCAATCCCGCTTCAGC
GGCCGAAAGCTCATCCGGTG

Product: transacetylase

Products: CoA; acetylmaltose [C]

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MALLDRNAVYPITLPDGCLYRDTVYLKNVVDHPRMEIGDFTYYTHSGRLEDTAVILAPYLGHSVRERLVIGKFVQIARGS
YFITSSANHPMTGFTTYPFRIFKPETFGYKDLPVKDTIVDHDVWIGQNAAIMPGVRIGHGAIVAAASVVARDVPPYAVVG
GNPASIIRMRYSSEVVSELLHLAWWDWPIDKIEANLGALDSGDIAALRLVQ

Sequences:

>Translated_211_residues
MALLDRNAVYPITLPDGCLYRDTVYLKNVVDHPRMEIGDFTYYTHSGRLEDTAVILAPYLGHSVRERLVIGKFVQIARGS
YFITSSANHPMTGFTTYPFRIFKPETFGYKDLPVKDTIVDHDVWIGQNAAIMPGVRIGHGAIVAAASVVARDVPPYAVVG
GNPASIIRMRYSSEVVSELLHLAWWDWPIDKIEANLGALDSGDIAALRLVQ
>Mature_210_residues
ALLDRNAVYPITLPDGCLYRDTVYLKNVVDHPRMEIGDFTYYTHSGRLEDTAVILAPYLGHSVRERLVIGKFVQIARGSY
FITSSANHPMTGFTTYPFRIFKPETFGYKDLPVKDTIVDHDVWIGQNAAIMPGVRIGHGAIVAAASVVARDVPPYAVVGG
NPASIIRMRYSSEVVSELLHLAWWDWPIDKIEANLGALDSGDIAALRLVQ

Specific function: Inactivates the A compounds of virginiamycin-like antibiotics, thus providing resistance to these antibiotics [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: 2.3.1.79 [C]

Molecular weight: Translated: 23402; Mature: 23271

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLDRNAVYPITLPDGCLYRDTVYLKNVVDHPRMEIGDFTYYTHSGRLEDTAVILAPYL
CCEECCCCEEEEECCCCCEEHHHHHHHHHHCCCCCEECCEEEEECCCCCCCCEEEEEHHH
GHSVRERLVIGKFVQIARGSYFITSSANHPMTGFTTYPFRIFKPETFGYKDLPVKDTIVD
CHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEECCEEEECCCCCCCCCCCCCCEEEC
HDVWIGQNAAIMPGVRIGHGAIVAAASVVARDVPPYAVVGGNPASIIRMRYSSEVVSELL
CCEEECCCCEECCCCEECCHHHHHHHHHHHHCCCCEEEECCCHHHEEEEEHHHHHHHHHH
HLAWWDWPIDKIEANLGALDSGDIAALRLVQ
HHHHCCCCHHHHHHCCCCCCCCCEEEEEEEC
>Mature Secondary Structure 
ALLDRNAVYPITLPDGCLYRDTVYLKNVVDHPRMEIGDFTYYTHSGRLEDTAVILAPYL
CEECCCCEEEEECCCCCEEHHHHHHHHHHCCCCCEECCEEEEECCCCCCCCEEEEEHHH
GHSVRERLVIGKFVQIARGSYFITSSANHPMTGFTTYPFRIFKPETFGYKDLPVKDTIVD
CHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEECCEEEECCCCCCCCCCCCCCEEEC
HDVWIGQNAAIMPGVRIGHGAIVAAASVVARDVPPYAVVGGNPASIIRMRYSSEVVSELL
CCEEECCCCEECCCCEECCHHHHHHHHHHHHCCCCEEEECCCHHHEEEEEHHHHHHHHHH
HLAWWDWPIDKIEANLGALDSGDIAALRLVQ
HHHHCCCCHHHHHHCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: 0.20 {glucose} 0.11 {maltose}

Km value (mM): 0.018 {acetyl-CoA}} 62 {glucose}} 40 {triethanolamine}} 90 {maltose}} [C]

Substrates: Acetyl-CoA; maltose [C]

Specific reaction: Acetyl-CoA + maltose = CoA + acetylmaltose [C]

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8344533; 3149758 [H]