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The map label for this gene is kdgR [H]

Identifier: 159184427

GI number: 159184427

Start: 706036

End: 706875

Strand: Direct

Name: kdgR [H]

Synonym: Atu0706

Alternate gene names: 159184427

Gene position: 706036-706875 (Clockwise)

Preceding gene: 15888045

Following gene: 159184428

Centisome position: 24.85

GC content: 61.9

Gene sequence:

>840_bases
ATGCCTGATGATAAAAAAGCCAATGGCGGAAAGCCCGATGCGGTTCCGCCCTCACACCAGAAAACCGAAAACGCCACCGG
CACGCTCGGCAAGGTCGTCTCGCTGCTGGAACTGATCGCCCTTGCCGAAAAGCCGATGCGTTTTACCGATGTCGTCGAGG
CAAGCGGTCAGCCTCGCGGCACGGTTCACCGCCAGCTCGCGCATCTGGTTGCCGAGGGCCTGGTGGATCATGCCGCCGAT
CAGACCTATGCGGTGGGGCTGAGGCTCCTGCAACTGGCGGCGAAGGCCTGGAGCGGCAATGATCTGCGCAACGTCGCAGC
ACCTCATCTTTCGGCCTTGCAGGAAGCGACGCAGGAATCCGTGCATCTCGCCGTTCTGAACGGCGGGCAGGTCACCTATC
TCGACAAGATGGAGGGTCGCCATACATTGCGCATGCATTCGCAGGTCGGCAAAACCTCGCCGGCCTATTGCACGGGGGTG
GGCAAGGCGGCGCTGTCGCTGCTGCCCGTCGATGAGCTGGCGGAACTTGCCGCAGGAATGGAGTTTCACCGTTTCACGGA
GGCGACGCTGATAACGCCGGAAGCCCTGATGGCCGATGTCGCCGCCATCTGCGACAATGGTTACGGTTTCGATCTTCAGG
AACATGAAATCGGAATTCATTGCGTCGCCGCACCGGTCCGGGCGCGGGGCCGCAATTTTGTGGCGGCGATCTCGGTCACC
GGTCCCGCCTACCGGGTGGATGCGGAACAGCTGCGCAACTGGGCGCCGCTGGTGCGCGAAACGGCCGATAAAATCTCTGC
GGAACTCGCCTGCAGATTATCCCCGGTTGCGGATGATTGA

Upstream 100 bases:

>100_bases
GAAAGGCTTGATTGTTCCATTATTTGGAACTAAATTTTACTAAGTGGAATTATTCTCTTGGCGTCTCGATGATGTCAAGA
CCGATGACGGTGGATGGCGC

Downstream 100 bases:

>100_bases
GAGAAAAACGGCGCGCCCCGTCGGGTTTCTCCGCCAGAATTGGCCGTGAGGACACTCATACATGTGTGTTAGTAATTATT
TTCGACTATTCGGAATTAAA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MPDDKKANGGKPDAVPPSHQKTENATGTLGKVVSLLELIALAEKPMRFTDVVEASGQPRGTVHRQLAHLVAEGLVDHAAD
QTYAVGLRLLQLAAKAWSGNDLRNVAAPHLSALQEATQESVHLAVLNGGQVTYLDKMEGRHTLRMHSQVGKTSPAYCTGV
GKAALSLLPVDELAELAAGMEFHRFTEATLITPEALMADVAAICDNGYGFDLQEHEIGIHCVAAPVRARGRNFVAAISVT
GPAYRVDAEQLRNWAPLVRETADKISAELACRLSPVADD

Sequences:

>Translated_279_residues
MPDDKKANGGKPDAVPPSHQKTENATGTLGKVVSLLELIALAEKPMRFTDVVEASGQPRGTVHRQLAHLVAEGLVDHAAD
QTYAVGLRLLQLAAKAWSGNDLRNVAAPHLSALQEATQESVHLAVLNGGQVTYLDKMEGRHTLRMHSQVGKTSPAYCTGV
GKAALSLLPVDELAELAAGMEFHRFTEATLITPEALMADVAAICDNGYGFDLQEHEIGIHCVAAPVRARGRNFVAAISVT
GPAYRVDAEQLRNWAPLVRETADKISAELACRLSPVADD
>Mature_278_residues
PDDKKANGGKPDAVPPSHQKTENATGTLGKVVSLLELIALAEKPMRFTDVVEASGQPRGTVHRQLAHLVAEGLVDHAADQ
TYAVGLRLLQLAAKAWSGNDLRNVAAPHLSALQEATQESVHLAVLNGGQVTYLDKMEGRHTLRMHSQVGKTSPAYCTGVG
KAALSLLPVDELAELAAGMEFHRFTEATLITPEALMADVAAICDNGYGFDLQEHEIGIHCVAAPVRARGRNFVAAISVTG
PAYRVDAEQLRNWAPLVRETADKISAELACRLSPVADD

Specific function: Transcriptional Regulator Of The Kdgk Gene For The Kdg Kinase And The Kdgt Gene For The Kdg Permease. [C]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=256, Percent_Identity=29.296875, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1786468, Length=225, Percent_Identity=30.2222222222222, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87082359, Length=251, Percent_Identity=29.0836653386454, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1786715, Length=267, Percent_Identity=27.3408239700375, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788581, Length=221, Percent_Identity=28.5067873303167, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789999, Length=256, Percent_Identity=27.34375, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29776; Mature: 29645

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDDKKANGGKPDAVPPSHQKTENATGTLGKVVSLLELIALAEKPMRFTDVVEASGQPRG
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCH
TVHRQLAHLVAEGLVDHAADQTYAVGLRLLQLAAKAWSGNDLRNVAAPHLSALQEATQES
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
VHLAVLNGGQVTYLDKMEGRHTLRMHSQVGKTSPAYCTGVGKAALSLLPVDELAELAAGM
EEEEEEECCEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCC
EFHRFTEATLITPEALMADVAAICDNGYGFDLQEHEIGIHCVAAPVRARGRNFVAAISVT
HHHHHHHHHEECHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHCCCCEEEEEEEC
GPAYRVDAEQLRNWAPLVRETADKISAELACRLSPVADD
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PDDKKANGGKPDAVPPSHQKTENATGTLGKVVSLLELIALAEKPMRFTDVVEASGQPRG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCH
TVHRQLAHLVAEGLVDHAADQTYAVGLRLLQLAAKAWSGNDLRNVAAPHLSALQEATQES
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
VHLAVLNGGQVTYLDKMEGRHTLRMHSQVGKTSPAYCTGVGKAALSLLPVDELAELAAGM
EEEEEEECCEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCC
EFHRFTEATLITPEALMADVAAICDNGYGFDLQEHEIGIHCVAAPVRARGRNFVAAISVT
HHHHHHHHHEECHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHCCCCEEEEEEEC
GPAYRVDAEQLRNWAPLVRETADKISAELACRLSPVADD
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]