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The map label for this gene is aspB [H]

Identifier: 159184355

GI number: 159184355

Start: 522122

End: 523288

Strand: Direct

Name: aspB [H]

Synonym: Atu0529

Alternate gene names: 159184355

Gene position: 522122-523288 (Clockwise)

Preceding gene: 15887877

Following gene: 15887879

Centisome position: 18.37

GC content: 60.58

Gene sequence:

>1167_bases
ATGTCCATTTTGAACAGTCTGAGTGCGCGCTCTCTGGCAGCGCCCGAGAGCGGTATTGTCGAAGTCGTGAATTATGCCCG
GGGGCGGGACAATCTCCTGCCGCTCTGGGTTGGTGAAGGCGATCTGCCGAGCCCCGACTTCATCAATCAGGCCGCCATCG
ATGGGCTGAACAATGGTGAAACCTTCTATACCTGGCAGCGCGGCATTCCGGAATTGCGGCAGGCGCTGAGCCACTATTAC
GAGCGGCATTTCGCGGCGTCGCTGCCGCCGGAGCATTTTTACGCCACCGGTTCCGGCATGCAGGCGATCGTGCTTGCCGT
GCAGGCACTGACCTCGCCGGGTGACGAGATGGTGTATCTTTCGCCTACATGGCCCAATATCGTCGCAGCCATCGGTGTGG
CCGGCGCAAAGGCGGTTCCGGTCGGCATCGATTTCCGCGATGGTCGTTGGGATCTCGATATCAACAGGCTGGAAAGCGCG
ATTACCGGCAAGACGAAGGCGCTCTTCATCAACACGCCCTCCAACCCCACCGGATGGACGGCAACACGCGACAATCTTCG
TGACGTTCTGGCGCTCGCCCGCAAACACGATCTGTGGATCGTCGCGGACGAAATCTATGCGCTTTATCACTATGCCGGCA
GCCGCGCGCCGTCCTTCCTGGATGTGATGGAGCCGGACGACAAGATCGTCTTTGCCAACTCCTTCTCGAAGAACTGGTCG
ATGACCGGCTGGCGCGTCGGCTGGCTTGTTGCACCGCCGGCCATCGGTCAGGTGATCGAAAACCTCATTCAATATTCAAC
GTCAGGCGTGGCGCAGTTCATGCAGCGCGGTGCCGTCGCCGCCCTTGATCACGGTGATGGTTTCATCCGCGAGAACTACG
AACGCGCTTTGACCTCCCGCGACATTCTCTGTGATGCGCTGATCGCCACCAACCGTGTGGAAACCCTGAAACCGGATGGC
GCCCTTTATGCCTTCCTCAAGATCGACGGCGTCACCGACAGCCGCGCCACCGCGCTCGATATCGTCGACAAGACCGGCGT
TGGCCTTGCGCCCGGCACGGCCTTCGGCCCAGGCGGAGAACTGTTCCTGCGCGCCTGCTTCCTGCGCAACCCCAGGCAGA
TAGAAGATGCGGCCGATCGGCTGGCATCTTACATTCTCGGCAGGTAA

Upstream 100 bases:

>100_bases
GCCGGGGATGATCCATAAAGAAAATCCATGATCGCCTCACGGAATATCATGCACATGGCTGGTCCGATGCGATAAGAAGG
CACCAAACGGAGTGTCTTTA

Downstream 100 bases:

>100_bases
GCCTCGATCGTCCCTGCAACGGGTTTCCCCTGACGGGCAGGGCATCGCGCCGAAGTAGGGAAATCGGCAACAAAATCACA
GTAGAGACCTGAAACTGCAA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSILNSLSARSLAAPESGIVEVVNYARGRDNLLPLWVGEGDLPSPDFINQAAIDGLNNGETFYTWQRGIPELRQALSHYY
ERHFAASLPPEHFYATGSGMQAIVLAVQALTSPGDEMVYLSPTWPNIVAAIGVAGAKAVPVGIDFRDGRWDLDINRLESA
ITGKTKALFINTPSNPTGWTATRDNLRDVLALARKHDLWIVADEIYALYHYAGSRAPSFLDVMEPDDKIVFANSFSKNWS
MTGWRVGWLVAPPAIGQVIENLIQYSTSGVAQFMQRGAVAALDHGDGFIRENYERALTSRDILCDALIATNRVETLKPDG
ALYAFLKIDGVTDSRATALDIVDKTGVGLAPGTAFGPGGELFLRACFLRNPRQIEDAADRLASYILGR

Sequences:

>Translated_388_residues
MSILNSLSARSLAAPESGIVEVVNYARGRDNLLPLWVGEGDLPSPDFINQAAIDGLNNGETFYTWQRGIPELRQALSHYY
ERHFAASLPPEHFYATGSGMQAIVLAVQALTSPGDEMVYLSPTWPNIVAAIGVAGAKAVPVGIDFRDGRWDLDINRLESA
ITGKTKALFINTPSNPTGWTATRDNLRDVLALARKHDLWIVADEIYALYHYAGSRAPSFLDVMEPDDKIVFANSFSKNWS
MTGWRVGWLVAPPAIGQVIENLIQYSTSGVAQFMQRGAVAALDHGDGFIRENYERALTSRDILCDALIATNRVETLKPDG
ALYAFLKIDGVTDSRATALDIVDKTGVGLAPGTAFGPGGELFLRACFLRNPRQIEDAADRLASYILGR
>Mature_387_residues
SILNSLSARSLAAPESGIVEVVNYARGRDNLLPLWVGEGDLPSPDFINQAAIDGLNNGETFYTWQRGIPELRQALSHYYE
RHFAASLPPEHFYATGSGMQAIVLAVQALTSPGDEMVYLSPTWPNIVAAIGVAGAKAVPVGIDFRDGRWDLDINRLESAI
TGKTKALFINTPSNPTGWTATRDNLRDVLALARKHDLWIVADEIYALYHYAGSRAPSFLDVMEPDDKIVFANSFSKNWSM
TGWRVGWLVAPPAIGQVIENLIQYSTSGVAQFMQRGAVAALDHGDGFIRENYERALTSRDILCDALIATNRVETLKPDGA
LYAFLKIDGVTDSRATALDIVDKTGVGLAPGTAFGPGGELFLRACFLRNPRQIEDAADRLASYILGR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=262, Percent_Identity=28.2442748091603, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI95147551, Length=343, Percent_Identity=26.8221574344023, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI169881279, Length=343, Percent_Identity=26.8221574344023, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI56713256, Length=262, Percent_Identity=28.2442748091603, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI7705897, Length=403, Percent_Identity=26.5508684863524, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI33469970, Length=403, Percent_Identity=26.5508684863524, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI4507369, Length=304, Percent_Identity=26.3157894736842, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI169881281, Length=195, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1788722, Length=363, Percent_Identity=27.5482093663912, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788627, Length=359, Percent_Identity=28.4122562674095, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1786816, Length=356, Percent_Identity=23.876404494382, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787710, Length=299, Percent_Identity=26.0869565217391, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17567369, Length=389, Percent_Identity=21.8508997429306, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=241, Percent_Identity=26.5560165975104, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994476, Length=241, Percent_Identity=26.5560165975104, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17567663, Length=297, Percent_Identity=25.5892255892256, Blast_Score=95, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6322401, Length=200, Percent_Identity=30, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320317, Length=388, Percent_Identity=19.5876288659794, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28573069, Length=389, Percent_Identity=23.6503856041131, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646114, Length=389, Percent_Identity=23.6503856041131, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573067, Length=389, Percent_Identity=23.6503856041131, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573065, Length=389, Percent_Identity=23.6503856041131, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI18859735, Length=387, Percent_Identity=23.2558139534884, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42330; Mature: 42199

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILNSLSARSLAAPESGIVEVVNYARGRDNLLPLWVGEGDLPSPDFINQAAIDGLNNGE
CCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCC
TFYTWQRGIPELRQALSHYYERHFAASLPPEHFYATGSGMQAIVLAVQALTSPGDEMVYL
EEEEHHCCCHHHHHHHHHHHHHHHHCCCCHHHEEECCCCHHHHHHHHHHHCCCCCCEEEE
SPTWPNIVAAIGVAGAKAVPVGIDFRDGRWDLDINRLESAITGKTKALFINTPSNPTGWT
CCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCC
ATRDNLRDVLALARKHDLWIVADEIYALYHYAGSRAPSFLDVMEPDDKIVFANSFSKNWS
CCHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEECCCCCCC
MTGWRVGWLVAPPAIGQVIENLIQYSTSGVAQFMQRGAVAALDHGDGFIRENYERALTSR
CCCEEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
DILCDALIATNRVETLKPDGALYAFLKIDGVTDSRATALDIVDKTGVGLAPGTAFGPGGE
HHHHHHHHHCCCHHEECCCCCEEEEEEEECCCCCCCCEEEEHHCCCCCCCCCCCCCCCHH
LFLRACFLRNPRQIEDAADRLASYILGR
HHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILNSLSARSLAAPESGIVEVVNYARGRDNLLPLWVGEGDLPSPDFINQAAIDGLNNGE
CHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCC
TFYTWQRGIPELRQALSHYYERHFAASLPPEHFYATGSGMQAIVLAVQALTSPGDEMVYL
EEEEHHCCCHHHHHHHHHHHHHHHHCCCCHHHEEECCCCHHHHHHHHHHHCCCCCCEEEE
SPTWPNIVAAIGVAGAKAVPVGIDFRDGRWDLDINRLESAITGKTKALFINTPSNPTGWT
CCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCC
ATRDNLRDVLALARKHDLWIVADEIYALYHYAGSRAPSFLDVMEPDDKIVFANSFSKNWS
CCHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEECCCCCCC
MTGWRVGWLVAPPAIGQVIENLIQYSTSGVAQFMQRGAVAALDHGDGFIRENYERALTSR
CCCEEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
DILCDALIATNRVETLKPDGALYAFLKIDGVTDSRATALDIVDKTGVGLAPGTAFGPGGE
HHHHHHHHHCCCHHEECCCCCEEEEEEEECCCCCCCCEEEEHHCCCCCCCCCCCCCCCHH
LFLRACFLRNPRQIEDAADRLASYILGR
HHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]