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The map label for this gene is cheA [H]

Identifier: 159184352

GI number: 159184352

Start: 506474

End: 508687

Strand: Direct

Name: cheA [H]

Synonym: Atu0517

Alternate gene names: 159184352

Gene position: 506474-508687 (Clockwise)

Preceding gene: 15887864

Following gene: 15887866

Centisome position: 17.82

GC content: 61.83

Gene sequence:

>2214_bases
CTGGAATCGGGGCTTCTTAAATTGAATGACGGGGACCGTGATCCGGAAACCGTCAACGCCGTTTTCCGTGCCGTTCATTC
CATCAAGGGCGGGGCCGGTGCCTTTGGTCTCGATGATCTCGTGGCCTTCGCCCACGTTTTTGAAACGACCCTCGACTGCG
TTCGCTCCAACAAGCTGGAACCGACACAGGACGTTCTAAAAGTCATGCTGCGCTCCGCCGATGTGCTGGCGGATCTGACC
AACGCGGCCAGAGACGGCGGCAGCGTCGATGAAAGCCGCACCCGTGGCCTCGTCAAGGAACTGGAAGCGCTGGCCAATGG
CGAAGCCGTTCCGGCATCCGCGCCGGCTCCTGTCGCTGTTAAGGCGCCGGAACCCGTCAAGGCGCCCGCAGCACCGAAGC
CGACGGATGAAAGCGGTTTCGAGCCGATCCCGTTCTCTTTCTCCGATTTTGCCGACGAGACGACGCCGCTGATGGAGGTG
CCGACCTTCCAGATTACGTTCAAGCCGCACGCCTCGCTTTATTCCAAGGGCAATGAGGCGGCACTTCTGCTACGTGATCT
CTCGCGCATCGGCGACATGAGCGTCAATTGCGACATGTCCGACCTGCCGGCGCTCGACAAGCTCGATCCCGAAGCCTCCT
ATCTCTCCTGGACGGTTTCCATCGCCACCGAAAAGGGTGAGGAAGGAATCCGCAGCGTCTTCGAATTCGCCGAATGGGAT
TGCGATCTCGAAATCACCGCAGTTGTTTCGGACGCGTCCGCGGACGAAGAAGAACTGCCGATGATCCCGGTTCCGTTCGA
TCTGTCTGCTCTCGATGGTGATGCGCAGGACGAACCCGCCGTCGCGACCCCCGCGATGGAAGATGCCTACGTTGCCGCAA
CCGTCGAAGCTGCCGTCGCGACGACGCAGATCGCCCAGAGCGTCAATGCCGCTATCGAAAAGCGCGAGGCGGCGGCAGCG
CCGGCCGCAGCGCAGGCGAACGCCAATGCCGCCGCCAATGCGAGTGCCGGCCAGACCATCCGCGTCGACCTCGATCGCGT
CGACCGCCTGATCAATCTCGTCGGCGAGCTTGTCATCAATCAGGCGATGCTGTCGCAGAGCGTCATCGAAAACGATGCGA
GCGGCACCTCCGCCGTTAATATGGGTCTGGACGAGCTGCAGCAGCTGACGCGCGAAATCCAGGACAGCGTCATGGCCATC
CGCGCGCAGCCGGTGAAGCCCGTCTTCCAGCGCATGTCGCGTATCGTCCGCGAAGTCGCCGACATGATCGGCAAGCAGAT
CCGCCTCGTCACCGAAGGTGAGAACACGGAAGTCGACAAGACGGTCATCGACAAGCTGGCCGAACCCCTGACCCACATGA
TCCGCAATGCCGTCGACCATGGCATCGAGACGCCGGAAAAGCGCGAAGCCGCGGGCAAGAACCCGGAAGGCACCATCAAG
CTTTCGGCCAAGCACCGTTCGGGCCGTATCCTCATCGAGCTTCAGGACGATGGCGCCGGCATCAACCGTGAGCGCGTCCG
CCAGAAGGCGATCGACAACGATCTGATTGCCGCCGATGCGAACCTGACCGACGAGGAGATCGACAATCTGATCTTCGCGC
CGGGCTTCTCGACGGCAGACAAGATTTCCGACATTTCCGGCCGCGGTGTGGGCATGGATGTGGTCAAGCGTTCCATTCAG
GCGCTCGGCGGCCGCATCAGCATCTCGTCGCGTCCGGGCCTCGGCTCGACCTTCACCATGAGCCTGCCGCTGACGCTTGC
CGTTCTCGACGGTATGGTGGTGACCGTGGCCGGTCAGACGCTCGTCGTTCCTCTGACGGCAATCGTCGAAACCCTGCAGC
CGGAAGCGAAGAACATCCACTCCTTCGGTTCCAACCAGCGGCTGATCTCCATCCGCAACTCCTTCTGCCCGCTGGTGGAT
GTCGGTCGTGTCCTGAACTTCCGTCCGACCCAGGCCGATCCTGTCGAAGGTGTGGCGCTTCTGGTGGAATCGGAAGGCGG
CGGCCAACGTGCTCTGATGGTCGATGCGATCCAGGGCCAGCGCCAGGTCGTCATCAAATCTTTGGAAGCCAACTATACCC
ATGTTCCGGGCATCGCCGCCGCCACCATTCTCGGTGACGGACGTGTAGCGCTCATTCTGGATGTCGATGCCATCGTCAGC
GCCTCGCGCGGACAGCCACTGAAACAGGAAATGTCACTCGCGGCGACGGGTTGA

Upstream 100 bases:

>100_bases
GCCATTGAGCGCGTAACCGCCTGATACGGGACATTTCACGATGGATATGAACGAAATCAAGGAAATCTTTTTCCAGGAGT
GCGAGGAACAGCTCGCTGAA

Downstream 100 bases:

>100_bases
AGGCGGATATCCAATGGCAGCACTTAATCTCAGCGATCAGCGACAGTCTCCCGATGACGTTCTTGCCAGCGGCGAATATC
CGCTGACACGGCGCGATTTG

Product: chemotaxis protein histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 737; Mature: 737

Protein sequence:

>737_residues
MESGLLKLNDGDRDPETVNAVFRAVHSIKGGAGAFGLDDLVAFAHVFETTLDCVRSNKLEPTQDVLKVMLRSADVLADLT
NAARDGGSVDESRTRGLVKELEALANGEAVPASAPAPVAVKAPEPVKAPAAPKPTDESGFEPIPFSFSDFADETTPLMEV
PTFQITFKPHASLYSKGNEAALLLRDLSRIGDMSVNCDMSDLPALDKLDPEASYLSWTVSIATEKGEEGIRSVFEFAEWD
CDLEITAVVSDASADEEELPMIPVPFDLSALDGDAQDEPAVATPAMEDAYVAATVEAAVATTQIAQSVNAAIEKREAAAA
PAAAQANANAAANASAGQTIRVDLDRVDRLINLVGELVINQAMLSQSVIENDASGTSAVNMGLDELQQLTREIQDSVMAI
RAQPVKPVFQRMSRIVREVADMIGKQIRLVTEGENTEVDKTVIDKLAEPLTHMIRNAVDHGIETPEKREAAGKNPEGTIK
LSAKHRSGRILIELQDDGAGINRERVRQKAIDNDLIAADANLTDEEIDNLIFAPGFSTADKISDISGRGVGMDVVKRSIQ
ALGGRISISSRPGLGSTFTMSLPLTLAVLDGMVVTVAGQTLVVPLTAIVETLQPEAKNIHSFGSNQRLISIRNSFCPLVD
VGRVLNFRPTQADPVEGVALLVESEGGGQRALMVDAIQGQRQVVIKSLEANYTHVPGIAAATILGDGRVALILDVDAIVS
ASRGQPLKQEMSLAATG

Sequences:

>Translated_737_residues
MESGLLKLNDGDRDPETVNAVFRAVHSIKGGAGAFGLDDLVAFAHVFETTLDCVRSNKLEPTQDVLKVMLRSADVLADLT
NAARDGGSVDESRTRGLVKELEALANGEAVPASAPAPVAVKAPEPVKAPAAPKPTDESGFEPIPFSFSDFADETTPLMEV
PTFQITFKPHASLYSKGNEAALLLRDLSRIGDMSVNCDMSDLPALDKLDPEASYLSWTVSIATEKGEEGIRSVFEFAEWD
CDLEITAVVSDASADEEELPMIPVPFDLSALDGDAQDEPAVATPAMEDAYVAATVEAAVATTQIAQSVNAAIEKREAAAA
PAAAQANANAAANASAGQTIRVDLDRVDRLINLVGELVINQAMLSQSVIENDASGTSAVNMGLDELQQLTREIQDSVMAI
RAQPVKPVFQRMSRIVREVADMIGKQIRLVTEGENTEVDKTVIDKLAEPLTHMIRNAVDHGIETPEKREAAGKNPEGTIK
LSAKHRSGRILIELQDDGAGINRERVRQKAIDNDLIAADANLTDEEIDNLIFAPGFSTADKISDISGRGVGMDVVKRSIQ
ALGGRISISSRPGLGSTFTMSLPLTLAVLDGMVVTVAGQTLVVPLTAIVETLQPEAKNIHSFGSNQRLISIRNSFCPLVD
VGRVLNFRPTQADPVEGVALLVESEGGGQRALMVDAIQGQRQVVIKSLEANYTHVPGIAAATILGDGRVALILDVDAIVS
ASRGQPLKQEMSLAATG
>Mature_737_residues
MESGLLKLNDGDRDPETVNAVFRAVHSIKGGAGAFGLDDLVAFAHVFETTLDCVRSNKLEPTQDVLKVMLRSADVLADLT
NAARDGGSVDESRTRGLVKELEALANGEAVPASAPAPVAVKAPEPVKAPAAPKPTDESGFEPIPFSFSDFADETTPLMEV
PTFQITFKPHASLYSKGNEAALLLRDLSRIGDMSVNCDMSDLPALDKLDPEASYLSWTVSIATEKGEEGIRSVFEFAEWD
CDLEITAVVSDASADEEELPMIPVPFDLSALDGDAQDEPAVATPAMEDAYVAATVEAAVATTQIAQSVNAAIEKREAAAA
PAAAQANANAAANASAGQTIRVDLDRVDRLINLVGELVINQAMLSQSVIENDASGTSAVNMGLDELQQLTREIQDSVMAI
RAQPVKPVFQRMSRIVREVADMIGKQIRLVTEGENTEVDKTVIDKLAEPLTHMIRNAVDHGIETPEKREAAGKNPEGTIK
LSAKHRSGRILIELQDDGAGINRERVRQKAIDNDLIAADANLTDEEIDNLIFAPGFSTADKISDISGRGVGMDVVKRSIQ
ALGGRISISSRPGLGSTFTMSLPLTLAVLDGMVVTVAGQTLVVPLTAIVETLQPEAKNIHSFGSNQRLISIRNSFCPLVD
VGRVLNFRPTQADPVEGVALLVESEGGGQRALMVDAIQGQRQVVIKSLEANYTHVPGIAAATILGDGRVALILDVDAIVS
ASRGQPLKQEMSLAATG

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=389, Percent_Identity=48.8431876606684, Blast_Score=394, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78235; Mature: 78235

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESGLLKLNDGDRDPETVNAVFRAVHSIKGGAGAFGLDDLVAFAHVFETTLDCVRSNKLE
CCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
PTQDVLKVMLRSADVLADLTNAARDGGSVDESRTRGLVKELEALANGEAVPASAPAPVAV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
KAPEPVKAPAAPKPTDESGFEPIPFSFSDFADETTPLMEVPTFQITFKPHASLYSKGNEA
ECCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEECCEEEEEECCCHHHHCCCCCH
ALLLRDLSRIGDMSVNCDMSDLPALDKLDPEASYLSWTVSIATEKGEEGIRSVFEFAEWD
HHHHHHHHHHCCCEECCCHHHCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCC
CDLEITAVVSDASADEEELPMIPVPFDLSALDGDAQDEPAVATPAMEDAYVAATVEAAVA
CCEEEEEEEECCCCCHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
TTQIAQSVNAAIEKREAAAAPAAAQANANAAANASAGQTIRVDLDRVDRLINLVGELVIN
HHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
QAMLSQSVIENDASGTSAVNMGLDELQQLTREIQDSVMAIRAQPVKPVFQRMSRIVREVA
HHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
DMIGKQIRLVTEGENTEVDKTVIDKLAEPLTHMIRNAVDHGIETPEKREAAGKNPEGTIK
HHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEE
LSAKHRSGRILIELQDDGAGINRERVRQKAIDNDLIAADANLTDEEIDNLIFAPGFSTAD
EEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCCEEEECCCCCHHHHCCEEECCCCCCHH
KISDISGRGVGMDVVKRSIQALGGRISISSRPGLGSTFTMSLPLTLAVLDGMVVTVAGQT
HHHCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCHHHHHHCCEEEEECCCC
LVVPLTAIVETLQPEAKNIHSFGSNQRLISIRNSFCPLVDVGRVLNFRPTQADPVEGVAL
HHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCEEE
LVESEGGGQRALMVDAIQGQRQVVIKSLEANYTHVPGIAAATILGDGRVALILDVDAIVS
EEECCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCHHEEEEECCCCEEEEEEHHHHHH
ASRGQPLKQEMSLAATG
CCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MESGLLKLNDGDRDPETVNAVFRAVHSIKGGAGAFGLDDLVAFAHVFETTLDCVRSNKLE
CCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
PTQDVLKVMLRSADVLADLTNAARDGGSVDESRTRGLVKELEALANGEAVPASAPAPVAV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
KAPEPVKAPAAPKPTDESGFEPIPFSFSDFADETTPLMEVPTFQITFKPHASLYSKGNEA
ECCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEECCEEEEEECCCHHHHCCCCCH
ALLLRDLSRIGDMSVNCDMSDLPALDKLDPEASYLSWTVSIATEKGEEGIRSVFEFAEWD
HHHHHHHHHHCCCEECCCHHHCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCC
CDLEITAVVSDASADEEELPMIPVPFDLSALDGDAQDEPAVATPAMEDAYVAATVEAAVA
CCEEEEEEEECCCCCHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
TTQIAQSVNAAIEKREAAAAPAAAQANANAAANASAGQTIRVDLDRVDRLINLVGELVIN
HHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
QAMLSQSVIENDASGTSAVNMGLDELQQLTREIQDSVMAIRAQPVKPVFQRMSRIVREVA
HHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
DMIGKQIRLVTEGENTEVDKTVIDKLAEPLTHMIRNAVDHGIETPEKREAAGKNPEGTIK
HHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEE
LSAKHRSGRILIELQDDGAGINRERVRQKAIDNDLIAADANLTDEEIDNLIFAPGFSTAD
EEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCCEEEECCCCCHHHHCCEEECCCCCCHH
KISDISGRGVGMDVVKRSIQALGGRISISSRPGLGSTFTMSLPLTLAVLDGMVVTVAGQT
HHHCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCHHHHHHCCEEEEECCCC
LVVPLTAIVETLQPEAKNIHSFGSNQRLISIRNSFCPLVDVGRVLNFRPTQADPVEGVAL
HHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCEEE
LVESEGGGQRALMVDAIQGQRQVVIKSLEANYTHVPGIAAATILGDGRVALILDVDAIVS
EEECCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCHHEEEEECCCCEEEEEEHHHHHH
ASRGQPLKQEMSLAATG
CCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]