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The map label for this gene is lhr [C]

Identifier: 159184341

GI number: 159184341

Start: 480100

End: 482478

Strand: Direct

Name: lhr [C]

Synonym: Atu0494

Alternate gene names: 159184341

Gene position: 480100-482478 (Clockwise)

Preceding gene: 159184338

Following gene: 15887842

Centisome position: 16.9

GC content: 61.92

Gene sequence:

>2379_bases
ATGCTGTTGATCGCGCCAACGGGCGCCGGCAAGACGCTCGGCGGTTTCATGGCGTCGCTCACCGATCTGGCGGAGCGCGG
CAAGGTGCCGCCCGGCTCCGGTTTTGTCGGCGTGCACACGCTCTATATCTCGCCTCTGAAGGCGCTTGCAGTGGATATCG
AGCGCAATCTCACGAGACCCGTTTCCGAAATGGGCCTGCCGATTGTGATCGAAACCCGCACGGGCGATACGCCGCAGGCC
AAACGCCAGCGCCAGAAGGTGAAGCCACCCGATATACTGCTGACAACACCGGAGCAGGTCTCGCTGCTGCTTGCCAATAA
GGAAGCCGAGCGCTTTTTCCGCGATCTGAAATATGTGGTTCTTGACGAACTGCATTCCCTCGTCACTTCCAAACGCGGCC
ACCTGCTGTCGCTGGCGCTCGCACGGGTGCGTCGGCACGCTCCTGACGTGCGCTTCATCGGCCTTTCGGCCACGGTGGCG
GAGCCGATGGATCTGCGTCGTTACCTTGCGCCACAGGGGCAAGGTGAGCCGCCGGCCGGCCTCATCACGGTGGAGGGTGG
AGCAAAACCGGACATTTCCATTTTGCACACGGAAGAACGCATTCCATGGTCTGGCCACTCCGCGCGTTATGCCGGCAAGG
ACTTATACGAGGCGTTGAAGCAGCATCAGACGACACTGGTCTTCGTCAACACGCGCTCACAGGCCGAACGGGTCTTCCAG
GAACTGTGGACCGTCAATGACGACAATCTGCCGATTGCGCTGCATCACGGCTCGCTGGATGCCGGCCAGCGCCGCAGGGT
GGAGGCGGCCATGGCGGAGAACAAGTTGCGCGCCGTCGTTGCCACCTCGACGCTTGATCTCGGCATAGACTGGGGCGATG
TCGACCTCGTCGTGCATGTCGGCGCGCCTAAAGGGGCTAGCCGCCTTGCCCAGCGCATCGGCCGTTCCAATCACCGCATG
GACGAGCCGTCAAAGGCGATCCTCGTTCCCGCCAACCGTTTCGAGGTGATGGAGTGCCGGGCAGCGCTGGATGCCAATTA
CATCGGCGCGCAGGATACCCCGCCTATCGCCGAAGGCGCGCTAGATGTTCTCGCCCAGCATGTGCTCGGTATGGCCTGCG
CCGAACCCTTCGATGCGGATGAACTTTATCGCGAAGTCACCAGCGCCTCGCCCTATGCCAACCTGCCGCGCGCTACCTTC
GACCGGGTGGTGGATTTCACCGCGACAGGCGGTTACGCGCTACGCACCTATGAGCGTTATGCCCGCATCCGCCAGATGAA
GGATGGCCGCTGGCGCGTTTCCAATCCGGCTGTCGCCCAGCAATATCGCCTGAACCTCGGCACCATCGTCGAGGCGGCGG
AACTCAATGTCCGCATGGTCAAGCGCAATGCCAAGGGCACGGTCGGACGCGGCGGCATGTCGCTCGGCAAGGTCGAGGAA
TATTTCTTGGAGCAACTGGTGCAGGGCGATACATTCCTGTTCGCCGGCAAGGTTCTGCGCTTCGAAGGCATCCGCGAGAA
TGAATGCCTGGTGTCGCAAGCCTTTTCCATGGACCCGAAAATACCCTCCTATGCTGGCGGCAAGTTTCCGCTTTCCACCT
ATTTGGCGGATCAGGTGCGCTCCATGCTTGCCGATCCCGCCCGCTGGCAGGCGCTGCCGGATCAGGTCCGCGACTGGCTG
GAAATCCAGAAGGAAAAGTCGATCATTCCCAAGCGCGACGAGTTGCTCGTCGAGACCTTCCCGTTCCGCAAACGCTTCTT
CATGGTCATGTATCCCTTCGAGGGACGGCTGGCGCACCAGACGCTCGGCATGCTTCTGACGCGGCGGCTGGAGCGCGCGG
GCGCAAAACCGATGGGTTTCGTCGCCACCGATTACTCGCTCGCCATATGGGCCATGGAGGATATCGGCATGCGGCTGAAA
TCCCGCCGCCTGTCGCTGGCGGACCTTCTCGACGAGGACATGCTGGGCGACGATCTGGAGGCGTGGCTGGATGAGTCCTT
CATGCTGAAACGCACGTTTCGCAATTGCGCCGTCATCTCTGGCCTCATCGAACGTCGCCATCCGGGCAAGGAAAAGACCG
GCCGGCAGGTCACGGTCTCAGCCGATCTTATTTATGACGTTCTTCGCAGCCATGAGCCGGATCATATCCTGCTGGAAGCG
ACGCGGCGGGATGCGGCGGCGGGACTTTTGGACATTGGCCGTCTTGGCGATATGCTGAAGCGAATCAAGGGCCACACCAC
CCATCGCGCGCTGGAGCATGTCTCGCCGCTTGCCGTTCCGGTGATGCTGGAAATCGGCCGCGAGACGGTGGCAGGTGAAG
CGATGGACGATGTGCTGGCCGAAGCCGCCGACGAGCTGATCGCGGAAGCCATGTCCTGA

Upstream 100 bases:

>100_bases
CACCTTGCCCCTTCCATTCCAGAAATGGTTTGCAGAAAAGGGATGGTCTCCGCGCGCCCATCAGCTGGAACTGATGGCGC
GGGCGCGGGGCGGTGAAAAC

Downstream 100 bases:

>100_bases
AGCATGAAATTGGAATGAAGGAACGACCACACAAGTGCTGAGCCGGCTGACATTGAGCGACAGGTTTTCAAATGGCTTCG
AATGCCTCGGCAGCGAAACC

Product: large atp-dependant helicase-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 792; Mature: 792

Protein sequence:

>792_residues
MLLIAPTGAGKTLGGFMASLTDLAERGKVPPGSGFVGVHTLYISPLKALAVDIERNLTRPVSEMGLPIVIETRTGDTPQA
KRQRQKVKPPDILLTTPEQVSLLLANKEAERFFRDLKYVVLDELHSLVTSKRGHLLSLALARVRRHAPDVRFIGLSATVA
EPMDLRRYLAPQGQGEPPAGLITVEGGAKPDISILHTEERIPWSGHSARYAGKDLYEALKQHQTTLVFVNTRSQAERVFQ
ELWTVNDDNLPIALHHGSLDAGQRRRVEAAMAENKLRAVVATSTLDLGIDWGDVDLVVHVGAPKGASRLAQRIGRSNHRM
DEPSKAILVPANRFEVMECRAALDANYIGAQDTPPIAEGALDVLAQHVLGMACAEPFDADELYREVTSASPYANLPRATF
DRVVDFTATGGYALRTYERYARIRQMKDGRWRVSNPAVAQQYRLNLGTIVEAAELNVRMVKRNAKGTVGRGGMSLGKVEE
YFLEQLVQGDTFLFAGKVLRFEGIRENECLVSQAFSMDPKIPSYAGGKFPLSTYLADQVRSMLADPARWQALPDQVRDWL
EIQKEKSIIPKRDELLVETFPFRKRFFMVMYPFEGRLAHQTLGMLLTRRLERAGAKPMGFVATDYSLAIWAMEDIGMRLK
SRRLSLADLLDEDMLGDDLEAWLDESFMLKRTFRNCAVISGLIERRHPGKEKTGRQVTVSADLIYDVLRSHEPDHILLEA
TRRDAAAGLLDIGRLGDMLKRIKGHTTHRALEHVSPLAVPVMLEIGRETVAGEAMDDVLAEAADELIAEAMS

Sequences:

>Translated_792_residues
MLLIAPTGAGKTLGGFMASLTDLAERGKVPPGSGFVGVHTLYISPLKALAVDIERNLTRPVSEMGLPIVIETRTGDTPQA
KRQRQKVKPPDILLTTPEQVSLLLANKEAERFFRDLKYVVLDELHSLVTSKRGHLLSLALARVRRHAPDVRFIGLSATVA
EPMDLRRYLAPQGQGEPPAGLITVEGGAKPDISILHTEERIPWSGHSARYAGKDLYEALKQHQTTLVFVNTRSQAERVFQ
ELWTVNDDNLPIALHHGSLDAGQRRRVEAAMAENKLRAVVATSTLDLGIDWGDVDLVVHVGAPKGASRLAQRIGRSNHRM
DEPSKAILVPANRFEVMECRAALDANYIGAQDTPPIAEGALDVLAQHVLGMACAEPFDADELYREVTSASPYANLPRATF
DRVVDFTATGGYALRTYERYARIRQMKDGRWRVSNPAVAQQYRLNLGTIVEAAELNVRMVKRNAKGTVGRGGMSLGKVEE
YFLEQLVQGDTFLFAGKVLRFEGIRENECLVSQAFSMDPKIPSYAGGKFPLSTYLADQVRSMLADPARWQALPDQVRDWL
EIQKEKSIIPKRDELLVETFPFRKRFFMVMYPFEGRLAHQTLGMLLTRRLERAGAKPMGFVATDYSLAIWAMEDIGMRLK
SRRLSLADLLDEDMLGDDLEAWLDESFMLKRTFRNCAVISGLIERRHPGKEKTGRQVTVSADLIYDVLRSHEPDHILLEA
TRRDAAAGLLDIGRLGDMLKRIKGHTTHRALEHVSPLAVPVMLEIGRETVAGEAMDDVLAEAADELIAEAMS
>Mature_792_residues
MLLIAPTGAGKTLGGFMASLTDLAERGKVPPGSGFVGVHTLYISPLKALAVDIERNLTRPVSEMGLPIVIETRTGDTPQA
KRQRQKVKPPDILLTTPEQVSLLLANKEAERFFRDLKYVVLDELHSLVTSKRGHLLSLALARVRRHAPDVRFIGLSATVA
EPMDLRRYLAPQGQGEPPAGLITVEGGAKPDISILHTEERIPWSGHSARYAGKDLYEALKQHQTTLVFVNTRSQAERVFQ
ELWTVNDDNLPIALHHGSLDAGQRRRVEAAMAENKLRAVVATSTLDLGIDWGDVDLVVHVGAPKGASRLAQRIGRSNHRM
DEPSKAILVPANRFEVMECRAALDANYIGAQDTPPIAEGALDVLAQHVLGMACAEPFDADELYREVTSASPYANLPRATF
DRVVDFTATGGYALRTYERYARIRQMKDGRWRVSNPAVAQQYRLNLGTIVEAAELNVRMVKRNAKGTVGRGGMSLGKVEE
YFLEQLVQGDTFLFAGKVLRFEGIRENECLVSQAFSMDPKIPSYAGGKFPLSTYLADQVRSMLADPARWQALPDQVRDWL
EIQKEKSIIPKRDELLVETFPFRKRFFMVMYPFEGRLAHQTLGMLLTRRLERAGAKPMGFVATDYSLAIWAMEDIGMRLK
SRRLSLADLLDEDMLGDDLEAWLDESFMLKRTFRNCAVISGLIERRHPGKEKTGRQVTVSADLIYDVLRSHEPDHILLEA
TRRDAAAGLLDIGRLGDMLKRIKGHTTHRALEHVSPLAVPVMLEIGRETVAGEAMDDVLAEAADELIAEAMS

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI40217847, Length=359, Percent_Identity=25.6267409470752, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI169218225, Length=359, Percent_Identity=25.6267409470752, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI76880486, Length=340, Percent_Identity=27.0588235294118, Blast_Score=80, Evalue=6e-15,
Organism=Escherichia coli, GI1787942, Length=829, Percent_Identity=26.5379975874548, Blast_Score=218, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17537519, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320497, Length=413, Percent_Identity=25.181598062954, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321710, Length=355, Percent_Identity=27.0422535211268, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI9755332, Length=320, Percent_Identity=24.6875, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321020, Length=352, Percent_Identity=23.8636363636364, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24647182, Length=373, Percent_Identity=26.0053619302949, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28574898, Length=362, Percent_Identity=26.2430939226519, Blast_Score=78, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 87996; Mature: 87996

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLIAPTGAGKTLGGFMASLTDLAERGKVPPGSGFVGVHTLYISPLKALAVDIERNLTRP
CEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCC
VSEMGLPIVIETRTGDTPQAKRQRQKVKPPDILLTTPEQVSLLLANKEAERFFRDLKYVV
HHHCCCCEEEECCCCCCHHHHHHHHCCCCCCEEEECHHHHEEEEECHHHHHHHHHHHHHH
LDELHSLVTSKRGHLLSLALARVRRHAPDVRFIGLSATVAEPMDLRRYLAPQGQGEPPAG
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCHHHCCHHHHHHHHCCCCCCCCCCE
LITVEGGAKPDISILHTEERIPWSGHSARYAGKDLYEALKQHQTTLVFVNTRSQAERVFQ
EEEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECHHHHHHHHH
ELWTVNDDNLPIALHHGSLDAGQRRRVEAAMAENKLRAVVATSTLDLGIDWGDVDLVVHV
HHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHEEEEEECEEEECCCCCCEEEEEEE
GAPKGASRLAQRIGRSNHRMDEPSKAILVPANRFEVMECRAALDANYIGAQDTPPIAEGA
CCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHH
LDVLAQHVLGMACAEPFDADELYREVTSASPYANLPRATFDRVVDFTATGGYALRTYERY
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHEEECCCCHHHHHHHHH
ARIRQMKDGRWRVSNPAVAQQYRLNLGTIVEAAELNVRMVKRNAKGTVGRGGMSLGKVEE
HHHHHHCCCCEECCCCHHHHHHHCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHH
YFLEQLVQGDTFLFAGKVLRFEGIRENECLVSQAFSMDPKIPSYAGGKFPLSTYLADQVR
HHHHHHHCCCEEEEECHHHEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
SMLADPARWQALPDQVRDWLEIQKEKSIIPKRDELLVETFPFRKRFFMVMYPFEGRLAHQ
HHHCCCHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEEECCCCCHHHH
TLGMLLTRRLERAGAKPMGFVATDYSLAIWAMEDIGMRLKSRRLSLADLLDEDMLGDDLE
HHHHHHHHHHHHCCCCCCCEEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AWLDESFMLKRTFRNCAVISGLIERRHPGKEKTGRQVTVSADLIYDVLRSHEPDHILLEA
HHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHCCCCCEEEEEE
TRRDAAAGLLDIGRLGDMLKRIKGHTTHRALEHVSPLAVPVMLEIGRETVAGEAMDDVLA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHH
EAADELIAEAMS
HHHHHHHHHHCC
>Mature Secondary Structure
MLLIAPTGAGKTLGGFMASLTDLAERGKVPPGSGFVGVHTLYISPLKALAVDIERNLTRP
CEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCC
VSEMGLPIVIETRTGDTPQAKRQRQKVKPPDILLTTPEQVSLLLANKEAERFFRDLKYVV
HHHCCCCEEEECCCCCCHHHHHHHHCCCCCCEEEECHHHHEEEEECHHHHHHHHHHHHHH
LDELHSLVTSKRGHLLSLALARVRRHAPDVRFIGLSATVAEPMDLRRYLAPQGQGEPPAG
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCHHHCCHHHHHHHHCCCCCCCCCCE
LITVEGGAKPDISILHTEERIPWSGHSARYAGKDLYEALKQHQTTLVFVNTRSQAERVFQ
EEEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECHHHHHHHHH
ELWTVNDDNLPIALHHGSLDAGQRRRVEAAMAENKLRAVVATSTLDLGIDWGDVDLVVHV
HHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHEEEEEECEEEECCCCCCEEEEEEE
GAPKGASRLAQRIGRSNHRMDEPSKAILVPANRFEVMECRAALDANYIGAQDTPPIAEGA
CCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHH
LDVLAQHVLGMACAEPFDADELYREVTSASPYANLPRATFDRVVDFTATGGYALRTYERY
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHEEECCCCHHHHHHHHH
ARIRQMKDGRWRVSNPAVAQQYRLNLGTIVEAAELNVRMVKRNAKGTVGRGGMSLGKVEE
HHHHHHCCCCEECCCCHHHHHHHCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHH
YFLEQLVQGDTFLFAGKVLRFEGIRENECLVSQAFSMDPKIPSYAGGKFPLSTYLADQVR
HHHHHHHCCCEEEEECHHHEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
SMLADPARWQALPDQVRDWLEIQKEKSIIPKRDELLVETFPFRKRFFMVMYPFEGRLAHQ
HHHCCCHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEEECCCCCHHHH
TLGMLLTRRLERAGAKPMGFVATDYSLAIWAMEDIGMRLKSRRLSLADLLDEDMLGDDLE
HHHHHHHHHHHHCCCCCCCEEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AWLDESFMLKRTFRNCAVISGLIERRHPGKEKTGRQVTVSADLIYDVLRSHEPDHILLEA
HHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHCCCCCEEEEEE
TRRDAAAGLLDIGRLGDMLKRIKGHTTHRALEHVSPLAVPVMLEIGRETVAGEAMDDVLA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHH
EAADELIAEAMS
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]