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The map label for this gene is dapD

Identifier: 159184277

GI number: 159184277

Start: 364949

End: 365803

Strand: Reverse

Name: dapD

Synonym: Atu0371

Alternate gene names: 159184277

Gene position: 365803-364949 (Counterclockwise)

Preceding gene: 159184279

Following gene: 15887721

Centisome position: 12.87

GC content: 60.47

Gene sequence:

>855_bases
ATGAGCCTTACGGATCTTACCTCCCTCGAAACCATCATCGAAACCGCCTTCGACAACCGCGATGGTGTGAACGTATCGAC
GAAGGGCGAGGTTCGCGACGCGGTGAACACATCTCTTCAACTTCTCGACAGCGGCAAGGTTCGCGTCGCCGAGAAGCAGG
CGGACGGGAACTGGAAGGTGAATCAATGGCTGAAAAAGGCCGTGCTTCTATCCTTCCGGCTGAACGACATGGAAATCGTC
ACCGGTGGCCCCGGTGAATCGACTTGGTGGGACAAGGTGCCATCGAAGTTCGAGAACTGGGGTGAAAACCAGTTTCGCGC
CGCCGGCTTCCGCGCCGTGCCGAACGCCGTCGTGCGCCGCTCGGCTTACGTGGCCAAGAACGTCGTTCTGATGCCTTCCT
TCGTCAACCTCGGTGCCTATGTCGATGAAGGCACGATGGTCGACACCTGGGCAACCGTCGGCTCCTGCGCGCAGATCGGC
AAGAACGTGCATCTGTCCGGTGGCGTCGGCATCGGCGGCGTTCTGGAGCCGCTTCAGGCTGGCCCGACCATCATCGAGGA
TAATTGCTTCATCGGCGCCCGTTCAGAAGTCGTCGAAGGCTGCATCGTGCGTGAAGGCGCCGTTCTCGGCATGGGCGTGT
TCATCGGCAAGTCGACCAAGATCGTCGATCGCGCCACCGGCGAGATCACCTATGGCGAAGTGCCGCCCTATTCCGTCGTT
GTTGCCGGCACCATGCCGGGCAAACCTTTCCCGAACGGTGAACCGGGCCCGAGCCTTTATTGCGCCGTCATCGTCAAGCG
CGTCGATGAAAAGACCCGCTCCAAGACCGGCATCAACGAGCTTCTGCGCGACTGA

Upstream 100 bases:

>100_bases
TTGACGCCTTTCCAACACTCCCTTAGATCAAATGGCCAGAGCCTTCCAGCGGCGCGGGCCTTCCGTGACCGGACCACACG
CGACATTCAAGGAATTTTCC

Downstream 100 bases:

>100_bases
TAAAAGCTGATACCATGACCACGACCGATCCCGTTGCCAATCTCGCCGCCCTCATCCGTTGCCCGTCGGTAACGCCTGCG
GAAGGCGGCGCGCTTTCCCT

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSLTDLTSLETIIETAFDNRDGVNVSTKGEVRDAVNTSLQLLDSGKVRVAEKQADGNWKVNQWLKKAVLLSFRLNDMEIV
TGGPGESTWWDKVPSKFENWGENQFRAAGFRAVPNAVVRRSAYVAKNVVLMPSFVNLGAYVDEGTMVDTWATVGSCAQIG
KNVHLSGGVGIGGVLEPLQAGPTIIEDNCFIGARSEVVEGCIVREGAVLGMGVFIGKSTKIVDRATGEITYGEVPPYSVV
VAGTMPGKPFPNGEPGPSLYCAVIVKRVDEKTRSKTGINELLRD

Sequences:

>Translated_284_residues
MSLTDLTSLETIIETAFDNRDGVNVSTKGEVRDAVNTSLQLLDSGKVRVAEKQADGNWKVNQWLKKAVLLSFRLNDMEIV
TGGPGESTWWDKVPSKFENWGENQFRAAGFRAVPNAVVRRSAYVAKNVVLMPSFVNLGAYVDEGTMVDTWATVGSCAQIG
KNVHLSGGVGIGGVLEPLQAGPTIIEDNCFIGARSEVVEGCIVREGAVLGMGVFIGKSTKIVDRATGEITYGEVPPYSVV
VAGTMPGKPFPNGEPGPSLYCAVIVKRVDEKTRSKTGINELLRD
>Mature_283_residues
SLTDLTSLETIIETAFDNRDGVNVSTKGEVRDAVNTSLQLLDSGKVRVAEKQADGNWKVNQWLKKAVLLSFRLNDMEIVT
GGPGESTWWDKVPSKFENWGENQFRAAGFRAVPNAVVRRSAYVAKNVVLMPSFVNLGAYVDEGTMVDTWATVGSCAQIGK
NVHLSGGVGIGGVLEPLQAGPTIIEDNCFIGARSEVVEGCIVREGAVLGMGVFIGKSTKIVDRATGEITYGEVPPYSVVV
AGTMPGKPFPNGEPGPSLYCAVIVKRVDEKTRSKTGINELLRD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=279, Percent_Identity=65.5913978494624, Blast_Score=338, Evalue=2e-94,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_AGRT5 (Q8UIC6)

Other databases:

- EMBL:   AE007869
- PIR:   AC2622
- PIR:   C97404
- RefSeq:   NP_353403.2
- ProteinModelPortal:   Q8UIC6
- SMR:   Q8UIC6
- STRING:   Q8UIC6
- GeneID:   1132409
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0371
- eggNOG:   COG2171
- HOGENOM:   HBG704071
- OMA:   IMPSFIN
- PhylomeDB:   Q8UIC6
- ProtClustDB:   PRK11830
- BioCyc:   ATUM176299-1:ATU0371-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 30508; Mature: 30377

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 111-111 BINDING 148-148

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTDLTSLETIIETAFDNRDGVNVSTKGEVRDAVNTSLQLLDSGKVRVAEKQADGNWKV
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHEECCCCEEEEEECCCCCCHH
NQWLKKAVLLSFRLNDMEIVTGGPGESTWWDKVPSKFENWGENQFRAAGFRAVPNAVVRR
HHHHHHHHHHHEECCCEEEEECCCCCCCHHHHCCHHHHHCCCCCHHHCCCHHHHHHHHHH
SAYVAKNVVLMPSFVNLGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQA
HHHHHHCEEEECCHHCCCEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHC
GPTIIEDNCFIGARSEVVEGCIVREGAVLGMGVFIGKSTKIVDRATGEITYGEVPPYSVV
CCCEEECCCEECCHHHHHHHHHHCCCCEEEEEEEECCCCEEEECCCCCEEECCCCCEEEE
VAGTMPGKPFPNGEPGPSLYCAVIVKRVDEKTRSKTGINELLRD
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure 
SLTDLTSLETIIETAFDNRDGVNVSTKGEVRDAVNTSLQLLDSGKVRVAEKQADGNWKV
CCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHEECCCCEEEEEECCCCCCHH
NQWLKKAVLLSFRLNDMEIVTGGPGESTWWDKVPSKFENWGENQFRAAGFRAVPNAVVRR
HHHHHHHHHHHEECCCEEEEECCCCCCCHHHHCCHHHHHCCCCCHHHCCCHHHHHHHHHH
SAYVAKNVVLMPSFVNLGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQA
HHHHHHCEEEECCHHCCCEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHC
GPTIIEDNCFIGARSEVVEGCIVREGAVLGMGVFIGKSTKIVDRATGEITYGEVPPYSVV
CCCEEECCCEECCHHHHHHHHHHCCCCEEEEEEEECCCCEEEECCCCCEEECCCCCEEEE
VAGTMPGKPFPNGEPGPSLYCAVIVKRVDEKTRSKTGINELLRD
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194