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The map label for this gene is yajO [H]

Identifier: 159184235

GI number: 159184235

Start: 258027

End: 259028

Strand: Reverse

Name: yajO [H]

Synonym: Atu0260

Alternate gene names: 159184235

Gene position: 259028-258027 (Counterclockwise)

Preceding gene: 15887612

Following gene: 159184232

Centisome position: 9.12

GC content: 59.38

Gene sequence:

>1002_bases
ATGAAAAAAAGAACCCTCGGAAACAACCTTTCCGTTTCGGCGCTTGGCCTGGGCTGCATGGGAATGACCCATGCCTATAG
CCCGACCGGCGATGAAAACAGCGCAATAGCGACGCTGCACCGCGCCGTGGAACTTGGTGTCACCTTTTTTGATACGGCAG
AGGTTTATGGGCCTTACAATAACGAAATTCTCGTCGGCAAAGGTTTGAAGCCCTATCGCGATAAGGTGGTCATCGCCACC
AAGTTCGGTTTCAGGATCGACCCCAGCAAACCCGCAGGCCAGATGATGGTGGGCACCGACAGCCGGCCGGAAAACGTGCG
CGCCGTCGCAGAAGCTTCGCTCAAACGCCTCGGTGTCGATGTCATCGACCTGTTCTACCAGCACCGCGTCGATCCCAATG
TCCCGATCGAGGATACGCTAGGCGCCATGGCCGAGTTGGTCCAACAGGGCAAGGTGAAATATCTCGGCCTGTCGGAAGCG
AGCGCTGAAACTCTTCGCAAAGCGCACGCTGTTCATCCGATTGCGGCCATTCAGAGCGAATATTCGCTGTGGACCCGTGA
CGTGGAGGAAAACGGCGTGCTGGAAACCTGCCGCGAACTCGGCATCGGTTTTGTCCCCTTCAGCCCGCTCGGTCGCGGCG
CTTTGACGGGCGCGCTGAAGTCACTCGACGGCCTTGCCGCCGATGATTTCCGCCGCGGCCTGCCGCGCTTCCAAAGCGAG
AACTTCGACGCCAATCTGGCGCTCATCAAGCTTCTGGAGGACATGGCTGCCGAGAAGGGCGTCACCGCCGGGCAACTGGC
ACTCGCCTGGGTTCTGGCGCAGGGCGACTTCATCGTTCCAATCCCTGGCACCACGAAGATTGCCAACCTGGAAAAGAACG
TGGCTGCAACGGATGTTTCGCTGACGGCGGACGAAGTCGCCAGCCTCGGTGCGTTGCTCTCGCCGGCAAAGGTTGCAGGG
GAACGATATCCCGAACGCATGTCGCAGATGGCCAACCGCTAA

Upstream 100 bases:

>100_bases
ACAACCCAAGCGGATTTGCAGCGATTATTTTTACCGCCATGAGACGCTATTTTCTGATCACGCCCTGATGACGGGCGGTT
CCTTATGGAAGGACGAACAG

Downstream 100 bases:

>100_bases
AAAGAAAAGCCGCGGCAACTGCCGCGGCTTTTTTCATTCTATCATCCGCTCTCAGGCTTTCAGGCGCGTAGAACGCCGCC
CGTCGATTTCTCGACATTGC

Product: aldo-keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKKRTLGNNLSVSALGLGCMGMTHAYSPTGDENSAIATLHRAVELGVTFFDTAEVYGPYNNEILVGKGLKPYRDKVVIAT
KFGFRIDPSKPAGQMMVGTDSRPENVRAVAEASLKRLGVDVIDLFYQHRVDPNVPIEDTLGAMAELVQQGKVKYLGLSEA
SAETLRKAHAVHPIAAIQSEYSLWTRDVEENGVLETCRELGIGFVPFSPLGRGALTGALKSLDGLAADDFRRGLPRFQSE
NFDANLALIKLLEDMAAEKGVTAGQLALAWVLAQGDFIVPIPGTTKIANLEKNVAATDVSLTADEVASLGALLSPAKVAG
ERYPERMSQMANR

Sequences:

>Translated_333_residues
MKKRTLGNNLSVSALGLGCMGMTHAYSPTGDENSAIATLHRAVELGVTFFDTAEVYGPYNNEILVGKGLKPYRDKVVIAT
KFGFRIDPSKPAGQMMVGTDSRPENVRAVAEASLKRLGVDVIDLFYQHRVDPNVPIEDTLGAMAELVQQGKVKYLGLSEA
SAETLRKAHAVHPIAAIQSEYSLWTRDVEENGVLETCRELGIGFVPFSPLGRGALTGALKSLDGLAADDFRRGLPRFQSE
NFDANLALIKLLEDMAAEKGVTAGQLALAWVLAQGDFIVPIPGTTKIANLEKNVAATDVSLTADEVASLGALLSPAKVAG
ERYPERMSQMANR
>Mature_333_residues
MKKRTLGNNLSVSALGLGCMGMTHAYSPTGDENSAIATLHRAVELGVTFFDTAEVYGPYNNEILVGKGLKPYRDKVVIAT
KFGFRIDPSKPAGQMMVGTDSRPENVRAVAEASLKRLGVDVIDLFYQHRVDPNVPIEDTLGAMAELVQQGKVKYLGLSEA
SAETLRKAHAVHPIAAIQSEYSLWTRDVEENGVLETCRELGIGFVPFSPLGRGALTGALKSLDGLAADDFRRGLPRFQSE
NFDANLALIKLLEDMAAEKGVTAGQLALAWVLAQGDFIVPIPGTTKIANLEKNVAATDVSLTADEVASLGALLSPAKVAG
ERYPERMSQMANR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=313, Percent_Identity=29.3929712460064, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI4504825, Length=310, Percent_Identity=29.3548387096774, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI27436971, Length=332, Percent_Identity=30.421686746988, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI27436964, Length=316, Percent_Identity=30.0632911392405, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI27436966, Length=309, Percent_Identity=28.8025889967638, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI27436962, Length=309, Percent_Identity=28.8025889967638, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI223718702, Length=298, Percent_Identity=31.5436241610738, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI41327764, Length=227, Percent_Identity=33.0396475770925, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI41152114, Length=231, Percent_Identity=30.7359307359307, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI223718708, Length=135, Percent_Identity=37.7777777777778, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87081735, Length=336, Percent_Identity=35.1190476190476, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=33.3333333333333, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1788070, Length=318, Percent_Identity=32.0754716981132, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1787674, Length=320, Percent_Identity=30.9375, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1789199, Length=351, Percent_Identity=29.9145299145299, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788081, Length=305, Percent_Identity=28.5245901639344, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI48994888, Length=286, Percent_Identity=26.9230769230769, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325384, Length=347, Percent_Identity=30.5475504322767, Blast_Score=142, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6325169, Length=348, Percent_Identity=28.448275862069, Blast_Score=112, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6323998, Length=326, Percent_Identity=28.5276073619632, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6319958, Length=302, Percent_Identity=28.476821192053, Blast_Score=102, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6319951, Length=325, Percent_Identity=27.6923076923077, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322615, Length=258, Percent_Identity=28.2945736434109, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24640980, Length=329, Percent_Identity=27.0516717325228, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45549126, Length=326, Percent_Identity=27.3006134969325, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646159, Length=295, Percent_Identity=25.0847457627119, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24646155, Length=174, Percent_Identity=31.0344827586207, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35757; Mature: 35757

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRTLGNNLSVSALGLGCMGMTHAYSPTGDENSAIATLHRAVELGVTFFDTAEVYGPYN
CCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEECHHHCCCCC
NEILVGKGLKPYRDKVVIATKFGFRIDPSKPAGQMMVGTDSRPENVRAVAEASLKRLGVD
CEEEEECCCCCCCCCEEEEEECCEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCHH
VIDLFYQHRVDPNVPIEDTLGAMAELVQQGKVKYLGLSEASAETLRKAHAVHPIAAIQSE
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCHHHHHHHH
YSLWTRDVEENGVLETCRELGIGFVPFSPLGRGALTGALKSLDGLAADDFRRGLPRFQSE
HHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCC
NFDANLALIKLLEDMAAEKGVTAGQLALAWVLAQGDFIVPIPGTTKIANLEKNVAATDVS
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCEEEECCCCCEECCCCCCHHHCCCC
LTADEVASLGALLSPAKVAGERYPERMSQMANR
CCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKRTLGNNLSVSALGLGCMGMTHAYSPTGDENSAIATLHRAVELGVTFFDTAEVYGPYN
CCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEECHHHCCCCC
NEILVGKGLKPYRDKVVIATKFGFRIDPSKPAGQMMVGTDSRPENVRAVAEASLKRLGVD
CEEEEECCCCCCCCCEEEEEECCEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCHH
VIDLFYQHRVDPNVPIEDTLGAMAELVQQGKVKYLGLSEASAETLRKAHAVHPIAAIQSE
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCHHHHHHHH
YSLWTRDVEENGVLETCRELGIGFVPFSPLGRGALTGALKSLDGLAADDFRRGLPRFQSE
HHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCC
NFDANLALIKLLEDMAAEKGVTAGQLALAWVLAQGDFIVPIPGTTKIANLEKNVAATDVS
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCEEEECCCCCEECCCCCCHHHCCCC
LTADEVASLGALLSPAKVAGERYPERMSQMANR
CCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]