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The map label for this gene is tmk2 [H]

Identifier: 15898045

GI number: 15898045

Start: 1035182

End: 1035808

Strand: Reverse

Name: tmk2 [H]

Synonym: SSO1191

Alternate gene names: 15898045

Gene position: 1035808-1035182 (Counterclockwise)

Preceding gene: 15898046

Following gene: 15898044

Centisome position: 34.62

GC content: 34.29

Gene sequence:

>627_bases
GTGAATATATTGATAATAGCCTTTGAGGGAATTGAAGGTTCTGGGAAAACATCTCATCTAGAGGCTACTAAAAAGTATTT
GGAGAAAGAAGGATATGGAGTAGTTACATTTGGGTTACAGATGTCTAAATTAATAGGAGATAGAATAGCACAAGTCAAGA
GGAATATAATATTTGAAAGGAGAACATTGTTTTTAGCTTATGTCACAGACTTGGCTGACCAAATTGAGAATTATGTTAAA
CCATCAATAGATTCTGGATTTATAGCCTTAGCTGATGGTTACACATTAACATTAACTTCTTGGGGATTAACCAGAGGTTT
AGAGAAGGAATGGATAGATGACGTCCTCTCAATGCTTCCTAAACCTTCAATCTCTTTACCACTGATATCAACACCAGATG
AAATAGTAAGAAGGATAATAAAGAAAAGGGGTTATCTGGATCCATTAGAAACCGGAATAGATATATGCATCAAGGAGGAC
ACATTTGAGGCCTACATAGATTATATTAATAGGTTTCAAGAAGCTTTAATGTCAATTTCCTCTAGAGAAAACATAATATA
CACTGACAAGGAATTTGATGAGGTACAGAAGGAGATAGTGAGAAGAATTGACAATATCACAAGTTAA

Upstream 100 bases:

>100_bases
GAGATTTACGATAAAATAGCTAAAGAGGAAAGCAACTTCATAACAATAGACGGAAATAGACCATTAAAGGACGTTCAGAT
TGATATAAGAAAAATTTTAG

Downstream 100 bases:

>100_bases
GGATTACCTTAACCTACAGCTCAAAAAGGCTATCCAAATAAACGGTATTGGCGTTGAGGAAATTCACGATATGAGAGTGG
CTGTGAGAAAGTATTTCGAT

Product: thymidylate kinase related protein

Products: NA

Alternate protein names: dTMP kinase 2 [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MNILIIAFEGIEGSGKTSHLEATKKYLEKEGYGVVTFGLQMSKLIGDRIAQVKRNIIFERRTLFLAYVTDLADQIENYVK
PSIDSGFIALADGYTLTLTSWGLTRGLEKEWIDDVLSMLPKPSISLPLISTPDEIVRRIIKKRGYLDPLETGIDICIKED
TFEAYIDYINRFQEALMSISSRENIIYTDKEFDEVQKEIVRRIDNITS

Sequences:

>Translated_208_residues
MNILIIAFEGIEGSGKTSHLEATKKYLEKEGYGVVTFGLQMSKLIGDRIAQVKRNIIFERRTLFLAYVTDLADQIENYVK
PSIDSGFIALADGYTLTLTSWGLTRGLEKEWIDDVLSMLPKPSISLPLISTPDEIVRRIIKKRGYLDPLETGIDICIKED
TFEAYIDYINRFQEALMSISSRENIIYTDKEFDEVQKEIVRRIDNITS
>Mature_208_residues
MNILIIAFEGIEGSGKTSHLEATKKYLEKEGYGVVTFGLQMSKLIGDRIAQVKRNIIFERRTLFLAYVTDLADQIENYVK
PSIDSGFIALADGYTLTLTSWGLTRGLEKEWIDDVLSMLPKPSISLPLISTPDEIVRRIIKKRGYLDPLETGIDICIKED
TFEAYIDYINRFQEALMSISSRENIIYTDKEFDEVQKEIVRRIDNITS

Specific function: Phosphorylation Of Dtmp To Form Dtdp In Both De Novo And Salvage Pathways Of Dttp Synthesis. [C]

COG id: COG0125

COG function: function code F; Thymidylate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidylate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018094 [H]

Pfam domain/function: PF02223 Thymidylate_kin [H]

EC number: =2.7.4.9 [H]

Molecular weight: Translated: 23769; Mature: 23769

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILIIAFEGIEGSGKTSHLEATKKYLEKEGYGVVTFGLQMSKLIGDRIAQVKRNIIFER
CCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
RTLFLAYVTDLADQIENYVKPSIDSGFIALADGYTLTLTSWGLTRGLEKEWIDDVLSMLP
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEECCHHHCCCHHHHHHHHHHHCC
KPSISLPLISTPDEIVRRIIKKRGYLDPLETGIDICIKEDTFEAYIDYINRFQEALMSIS
CCCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHH
SRENIIYTDKEFDEVQKEIVRRIDNITS
CCCCEEECCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNILIIAFEGIEGSGKTSHLEATKKYLEKEGYGVVTFGLQMSKLIGDRIAQVKRNIIFER
CCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
RTLFLAYVTDLADQIENYVKPSIDSGFIALADGYTLTLTSWGLTRGLEKEWIDDVLSMLP
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEECCHHHCCCHHHHHHHHHHHCC
KPSISLPLISTPDEIVRRIIKKRGYLDPLETGIDICIKEDTFEAYIDYINRFQEALMSIS
CCCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHH
SRENIIYTDKEFDEVQKEIVRRIDNITS
CCCCEEECCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726 [H]